BacMap

Definition	Synechococcus sp. PCC 7002 chromosome, complete genome.
Accession	NC_010475
Length	3,008,047

Click here to switch to the map view.

The map label for this gene is ppiB [C]

Identifier: 170078234

GI number: 170078234

Start: 1706085

End: 1706609

Strand: Direct

Name: ppiB [C]

Synonym: SYNPCC7002_A1626

Alternate gene names: 170078234

Gene position: 1706085-1706609 (Clockwise)

Preceding gene: 170078231

Following gene: 170078235

Centisome position: 56.72

GC content: 52.0

Gene sequence:

>525_bases
GTGAGCGAACAGCCCAACCCCAAAGTTTTTTTTGACATCACCATCGGCGGCGAAAGTGCCGGACGCATTGTTTTTGAACT
ACGGGCCGACGTTGCCCCCAAAACCGCTGAAAATTTCCGCGCCCTCTGCACTGGTGAAAAAGGCATCGGCAAACGGGGCA
AACCCCTCCATTTCAAAGGCTCTAAATTCCACCGGGTGATCCCTGAATTCATGTGCCAAGGGGGAGACTTTACCAACGGT
AACGGCACCGGCGGTGAATCCATTTATGGAGATACTTTTGAAGACGAAAGCTTTGAACTGCGCCACAATGTCCCAGGTTT
GCTGAGTATGGCGAACCGTGGCCCCAATACCAATGGCTCCCAATTCTTCATCACCACGACCTTAACCCCTTGGCTCAACG
GTAAGCACGTGGTCTTCGGTAAGGTTATCGAAGGGATGGATGTAGTCAAAGCTATGGAAGCCCAAGGTTCTGGTAGTGGT
GCCCCGAAACAGGAAATTGCGATCGCCGATTGTGGTGAGCTCTAA

Upstream 100 bases:

>100_bases
ATGAAGAATGTACTTCTTGATTTCTTTACGGGCGATCGCCCCTGACCACCCTTGCAGTACCATTTGGTTAAAGAGACGAC
ATTTTTTAGGACAAGTAATC

Downstream 100 bases:

>100_bases
ATCTGGCAGCACGGGACGCATTTAAAAAAATACTGCTGTTTTTGTTACGAAATGGGGGGAGAATTCCTGTCTATGATTAG
GGAACCAATATTCCCCCTTT

Product: peptidyl-prolyl cis-trans isomerase, cyclophilin-type

Products: NA

Alternate protein names: PPIase slr1251; Rotamase slr1251 [H]

Number of amino acids: Translated: 174; Mature: 173

Protein sequence:

>174_residues
MSEQPNPKVFFDITIGGESAGRIVFELRADVAPKTAENFRALCTGEKGIGKRGKPLHFKGSKFHRVIPEFMCQGGDFTNG
NGTGGESIYGDTFEDESFELRHNVPGLLSMANRGPNTNGSQFFITTTLTPWLNGKHVVFGKVIEGMDVVKAMEAQGSGSG
APKQEIAIADCGEL

Sequences:

>Translated_174_residues
MSEQPNPKVFFDITIGGESAGRIVFELRADVAPKTAENFRALCTGEKGIGKRGKPLHFKGSKFHRVIPEFMCQGGDFTNG
NGTGGESIYGDTFEDESFELRHNVPGLLSMANRGPNTNGSQFFITTTLTPWLNGKHVVFGKVIEGMDVVKAMEAQGSGSG
APKQEIAIADCGEL
>Mature_173_residues
SEQPNPKVFFDITIGGESAGRIVFELRADVAPKTAENFRALCTGEKGIGKRGKPLHFKGSKFHRVIPEFMCQGGDFTNGN
GTGGESIYGDTFEDESFELRHNVPGLLSMANRGPNTNGSQFFITTTLTPWLNGKHVVFGKVIEGMDVVKAMEAQGSGSGA
PKQEIAIADCGEL

Specific function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides [H]

COG id: COG0652

COG function: function code O; Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase cyclophilin-type domain [H]

Homologues:

Organism=Homo sapiens, GI5174637, Length=170, Percent_Identity=65.8823529411765, Blast_Score=234, Evalue=2e-62,
Organism=Homo sapiens, GI4826932, Length=174, Percent_Identity=65.5172413793103, Blast_Score=229, Evalue=7e-61,
Organism=Homo sapiens, GI5031987, Length=169, Percent_Identity=65.6804733727811, Blast_Score=226, Evalue=7e-60,
Organism=Homo sapiens, GI10863927, Length=169, Percent_Identity=66.8639053254438, Blast_Score=225, Evalue=1e-59,
Organism=Homo sapiens, GI42560244, Length=170, Percent_Identity=62.3529411764706, Blast_Score=210, Evalue=6e-55,
Organism=Homo sapiens, GI45439316, Length=152, Percent_Identity=65.1315789473684, Blast_Score=207, Evalue=3e-54,
Organism=Homo sapiens, GI169164185, Length=169, Percent_Identity=60.9467455621302, Blast_Score=207, Evalue=5e-54,
Organism=Homo sapiens, GI169163623, Length=169, Percent_Identity=60.9467455621302, Blast_Score=207, Evalue=5e-54,
Organism=Homo sapiens, GI169163387, Length=169, Percent_Identity=60.9467455621302, Blast_Score=206, Evalue=8e-54,
Organism=Homo sapiens, GI310129267, Length=167, Percent_Identity=61.0778443113772, Blast_Score=206, Evalue=9e-54,
Organism=Homo sapiens, GI310120620, Length=167, Percent_Identity=61.0778443113772, Blast_Score=206, Evalue=9e-54,
Organism=Homo sapiens, GI303305009, Length=151, Percent_Identity=64.9006622516556, Blast_Score=206, Evalue=1e-53,
Organism=Homo sapiens, GI5454154, Length=174, Percent_Identity=58.0459770114943, Blast_Score=202, Evalue=9e-53,
Organism=Homo sapiens, GI310110104, Length=167, Percent_Identity=59.8802395209581, Blast_Score=201, Evalue=2e-52,
Organism=Homo sapiens, GI150418007, Length=174, Percent_Identity=56.8965517241379, Blast_Score=201, Evalue=2e-52,
Organism=Homo sapiens, GI4758950, Length=168, Percent_Identity=57.7380952380952, Blast_Score=198, Evalue=2e-51,
Organism=Homo sapiens, GI310132444, Length=174, Percent_Identity=58.0459770114943, Blast_Score=197, Evalue=6e-51,
Organism=Homo sapiens, GI310113152, Length=174, Percent_Identity=58.0459770114943, Blast_Score=197, Evalue=6e-51,
Organism=Homo sapiens, GI178057341, Length=169, Percent_Identity=57.396449704142, Blast_Score=192, Evalue=1e-49,
Organism=Homo sapiens, GI310127646, Length=169, Percent_Identity=56.8047337278106, Blast_Score=191, Evalue=3e-49,
Organism=Homo sapiens, GI310114371, Length=169, Percent_Identity=56.8047337278106, Blast_Score=191, Evalue=3e-49,
Organism=Homo sapiens, GI310119221, Length=169, Percent_Identity=56.8047337278106, Blast_Score=191, Evalue=3e-49,
Organism=Homo sapiens, GI6631100, Length=176, Percent_Identity=54.5454545454545, Blast_Score=191, Evalue=3e-49,
Organism=Homo sapiens, GI209417936, Length=169, Percent_Identity=57.396449704142, Blast_Score=191, Evalue=4e-49,
Organism=Homo sapiens, GI30102944, Length=169, Percent_Identity=57.396449704142, Blast_Score=191, Evalue=4e-49,
Organism=Homo sapiens, GI219842199, Length=169, Percent_Identity=57.396449704142, Blast_Score=191, Evalue=4e-49,
Organism=Homo sapiens, GI169214050, Length=174, Percent_Identity=56.8965517241379, Blast_Score=189, Evalue=1e-48,
Organism=Homo sapiens, GI239751853, Length=169, Percent_Identity=57.9881656804734, Blast_Score=187, Evalue=4e-48,
Organism=Homo sapiens, GI113428306, Length=169, Percent_Identity=57.9881656804734, Blast_Score=187, Evalue=4e-48,
Organism=Homo sapiens, GI256017253, Length=169, Percent_Identity=56.8047337278106, Blast_Score=186, Evalue=7e-48,
Organism=Homo sapiens, GI221139811, Length=169, Percent_Identity=56.8047337278106, Blast_Score=186, Evalue=7e-48,
Organism=Homo sapiens, GI256017251, Length=169, Percent_Identity=56.8047337278106, Blast_Score=186, Evalue=7e-48,
Organism=Homo sapiens, GI4505991, Length=168, Percent_Identity=58.3333333333333, Blast_Score=186, Evalue=1e-47,
Organism=Homo sapiens, GI310127745, Length=167, Percent_Identity=56.8862275449102, Blast_Score=179, Evalue=1e-45,
Organism=Homo sapiens, GI310119290, Length=167, Percent_Identity=56.8862275449102, Blast_Score=179, Evalue=1e-45,
Organism=Homo sapiens, GI310114540, Length=167, Percent_Identity=56.8862275449102, Blast_Score=179, Evalue=2e-45,
Organism=Homo sapiens, GI27735045, Length=165, Percent_Identity=49.0909090909091, Blast_Score=167, Evalue=3e-42,
Organism=Homo sapiens, GI289803023, Length=191, Percent_Identity=42.4083769633508, Blast_Score=154, Evalue=5e-38,
Organism=Homo sapiens, GI7706339, Length=149, Percent_Identity=48.3221476510067, Blast_Score=121, Evalue=3e-28,
Organism=Homo sapiens, GI310132372, Length=169, Percent_Identity=44.3786982248521, Blast_Score=119, Evalue=2e-27,
Organism=Homo sapiens, GI310113085, Length=169, Percent_Identity=44.3786982248521, Blast_Score=119, Evalue=2e-27,
Organism=Homo sapiens, GI310123632, Length=169, Percent_Identity=44.3786982248521, Blast_Score=119, Evalue=2e-27,
Organism=Homo sapiens, GI24308049, Length=167, Percent_Identity=44.311377245509, Blast_Score=118, Evalue=3e-27,
Organism=Homo sapiens, GI19557636, Length=155, Percent_Identity=45.1612903225806, Blast_Score=117, Evalue=6e-27,
Organism=Homo sapiens, GI64276486, Length=125, Percent_Identity=47.2, Blast_Score=100, Evalue=9e-22,
Organism=Homo sapiens, GI22547212, Length=151, Percent_Identity=46.3576158940397, Blast_Score=99, Evalue=2e-21,
Organism=Homo sapiens, GI7657473, Length=151, Percent_Identity=46.3576158940397, Blast_Score=99, Evalue=2e-21,
Organism=Homo sapiens, GI22547215, Length=151, Percent_Identity=46.3576158940397, Blast_Score=97, Evalue=9e-21,
Organism=Homo sapiens, GI14277126, Length=160, Percent_Identity=38.125, Blast_Score=86, Evalue=1e-17,
Organism=Homo sapiens, GI20911035, Length=160, Percent_Identity=35.625, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17566266, Length=168, Percent_Identity=72.0238095238095, Blast_Score=259, Evalue=4e-70,
Organism=Caenorhabditis elegans, GI17559074, Length=167, Percent_Identity=73.0538922155689, Blast_Score=256, Evalue=3e-69,
Organism=Caenorhabditis elegans, GI17565860, Length=168, Percent_Identity=71.4285714285714, Blast_Score=253, Evalue=4e-68,
Organism=Caenorhabditis elegans, GI17552782, Length=171, Percent_Identity=72.5146198830409, Blast_Score=237, Evalue=2e-63,
Organism=Caenorhabditis elegans, GI17539498, Length=168, Percent_Identity=59.5238095238095, Blast_Score=210, Evalue=3e-55,
Organism=Caenorhabditis elegans, GI17551282, Length=171, Percent_Identity=58.4795321637427, Blast_Score=192, Evalue=8e-50,
Organism=Caenorhabditis elegans, GI17551284, Length=171, Percent_Identity=58.4795321637427, Blast_Score=192, Evalue=8e-50,
Organism=Caenorhabditis elegans, GI17552780, Length=168, Percent_Identity=57.1428571428571, Blast_Score=186, Evalue=7e-48,
Organism=Caenorhabditis elegans, GI17506307, Length=168, Percent_Identity=56.547619047619, Blast_Score=182, Evalue=8e-47,
Organism=Caenorhabditis elegans, GI17532643, Length=170, Percent_Identity=55.2941176470588, Blast_Score=181, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI17552784, Length=169, Percent_Identity=52.0710059171598, Blast_Score=180, Evalue=4e-46,
Organism=Caenorhabditis elegans, GI115533296, Length=175, Percent_Identity=44.5714285714286, Blast_Score=134, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17539496, Length=164, Percent_Identity=47.5609756097561, Blast_Score=127, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17506311, Length=165, Percent_Identity=46.6666666666667, Blast_Score=114, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71980594, Length=136, Percent_Identity=45.5882352941176, Blast_Score=110, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI71980590, Length=137, Percent_Identity=45.2554744525547, Blast_Score=110, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17532641, Length=151, Percent_Identity=40.3973509933775, Blast_Score=102, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI71996029, Length=168, Percent_Identity=36.3095238095238, Blast_Score=95, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71997782, Length=127, Percent_Identity=44.0944881889764, Blast_Score=91, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI32563659, Length=161, Percent_Identity=31.055900621118, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6320359, Length=167, Percent_Identity=63.4730538922156, Blast_Score=217, Evalue=7e-58,
Organism=Saccharomyces cerevisiae, GI6323246, Length=172, Percent_Identity=59.8837209302326, Blast_Score=208, Evalue=4e-55,
Organism=Saccharomyces cerevisiae, GI6323562, Length=167, Percent_Identity=62.2754491017964, Blast_Score=208, Evalue=5e-55,
Organism=Saccharomyces cerevisiae, GI6321848, Length=173, Percent_Identity=56.6473988439306, Blast_Score=179, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6320510, Length=168, Percent_Identity=52.9761904761905, Blast_Score=174, Evalue=5e-45,
Organism=Saccharomyces cerevisiae, GI6322492, Length=192, Percent_Identity=43.75, Blast_Score=132, Evalue=3e-32,
Organism=Saccharomyces cerevisiae, GI6319914, Length=166, Percent_Identity=34.3373493975904, Blast_Score=89, Evalue=3e-19,
Organism=Drosophila melanogaster, GI17647301, Length=173, Percent_Identity=67.0520231213873, Blast_Score=233, Evalue=6e-62,
Organism=Drosophila melanogaster, GI24664125, Length=168, Percent_Identity=66.0714285714286, Blast_Score=229, Evalue=9e-61,
Organism=Drosophila melanogaster, GI21357783, Length=168, Percent_Identity=66.0714285714286, Blast_Score=229, Evalue=9e-61,
Organism=Drosophila melanogaster, GI45549139, Length=168, Percent_Identity=65.4761904761905, Blast_Score=227, Evalue=3e-60,
Organism=Drosophila melanogaster, GI24650807, Length=170, Percent_Identity=64.7058823529412, Blast_Score=212, Evalue=1e-55,
Organism=Drosophila melanogaster, GI24661775, Length=170, Percent_Identity=55.8823529411765, Blast_Score=197, Evalue=3e-51,
Organism=Drosophila melanogaster, GI21355237, Length=170, Percent_Identity=55.8823529411765, Blast_Score=197, Evalue=3e-51,
Organism=Drosophila melanogaster, GI24661771, Length=170, Percent_Identity=55.8823529411765, Blast_Score=197, Evalue=3e-51,
Organism=Drosophila melanogaster, GI24586038, Length=170, Percent_Identity=53.5294117647059, Blast_Score=186, Evalue=9e-48,
Organism=Drosophila melanogaster, GI20130249, Length=168, Percent_Identity=55.952380952381, Blast_Score=185, Evalue=2e-47,
Organism=Drosophila melanogaster, GI17136360, Length=177, Percent_Identity=45.1977401129944, Blast_Score=159, Evalue=1e-39,
Organism=Drosophila melanogaster, GI17986117, Length=135, Percent_Identity=51.1111111111111, Blast_Score=120, Evalue=5e-28,
Organism=Drosophila melanogaster, GI19922376, Length=150, Percent_Identity=42.6666666666667, Blast_Score=106, Evalue=6e-24,
Organism=Drosophila melanogaster, GI24652460, Length=136, Percent_Identity=41.9117647058824, Blast_Score=101, Evalue=3e-22,
Organism=Drosophila melanogaster, GI19922912, Length=141, Percent_Identity=47.5177304964539, Blast_Score=98, Evalue=3e-21,
Organism=Drosophila melanogaster, GI21357249, Length=136, Percent_Identity=44.1176470588235, Blast_Score=97, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24650101, Length=179, Percent_Identity=31.8435754189944, Blast_Score=81, Evalue=3e-16,

Paralogues:

None

Copy number: 780 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015891
- InterPro:   IPR020892
- InterPro:   IPR002130 [H]

Pfam domain/function: PF00160 Pro_isomerase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 18698; Mature: 18567

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS00170 CSA_PPIASE_1 ; PS50072 CSA_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEQPNPKVFFDITIGGESAGRIVFELRADVAPKTAENFRALCTGEKGIGKRGKPLHFKG
CCCCCCCCEEEEEEECCCCCCEEEEEEECCCCCCCCHHHHEEECCCCCCCCCCCEEEECC
SKFHRVIPEFMCQGGDFTNGNGTGGESIYGDTFEDESFELRHNVPGLLSMANRGPNTNGS
CHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHCCCCCCCCC
QFFITTTLTPWLNGKHVVFGKVIEGMDVVKAMEAQGSGSGAPKQEIAIADCGEL
EEEEEEEECCCCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCC
>Mature Secondary Structure 
SEQPNPKVFFDITIGGESAGRIVFELRADVAPKTAENFRALCTGEKGIGKRGKPLHFKG
CCCCCCCEEEEEEECCCCCCEEEEEEECCCCCCCCHHHHEEECCCCCCCCCCCEEEECC
SKFHRVIPEFMCQGGDFTNGNGTGGESIYGDTFEDESFELRHNVPGLLSMANRGPNTNGS
CHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHCCCCCCCCC
QFFITTTLTPWLNGKHVVFGKVIEGMDVVKAMEAQGSGSGAPKQEIAIADCGEL
EEEEEEEECCCCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]