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The map label for this gene is pgk

Identifier: 170078194

GI number: 170078194

Start: 1667323

End: 1668519

Strand: Reverse

Name: pgk

Synonym: SYNPCC7002_A1585

Alternate gene names: 170078194

Gene position: 1668519-1667323 (Counterclockwise)

Preceding gene: 170078198

Following gene: 170078188

Centisome position: 55.47

GC content: 51.8

Gene sequence:

>1197_bases
GTGGCTAAGAAATCAGTTGCAAATTTAACAGAGGCAGATTTAAGCGGTAAGCGCGTGTTTGTCCGGGTTGATTTTAATGT
ACCCCTCAATGAGAGTGGTGTAATCACTGACGATACCCGGATTCGGGCAGCACTCCCCACCATCAAATATTTGACTGAGA
AAGGTGCCAAGGTAATTCTTGGGAGCCACATGGGTCGTCCGAAGGGTCAGGTGGTTGATTCGATGCGCTTAACGCCTGTG
GCCGCTCGTTTGTCTGAATTGTTGGGCCAATCTGTCACCAAGTGTGATGATTGCGTTGGAGATGCTGTGAACCAGGCGAT
CGCCAACCTCGGCAATGGTCAAGTGGCGTTACTAGAAAACCTCCGCTTTAACCCCGGCGAGGAAAAGAATGATCCCGAAT
TTGCCAAGCAACTCGCGGCCAATGCAGACATCTATGTCAACGATGCGTTCGGGACGGCTCACCGTGCCCATGGTTCCACC
GAAGGCGTAACCCACCACGTTGATACTTCCGTTGCGGGTCTTTTGATCGAAAAAGAACTCCAGTTCCTCAAGGGCGCCAT
CGAAGCCCCCAAACGTCCCCTCGTGGCGATTGTTGGCGGTTCTAAAGTATCCAGCAAAATTGGCGTCATCGAAACCCTCC
TCGAAAAGTGCGACAAGCTCTTGATCGGCGGCGGGATGATCTTTACGTTCTATAAAGCTCAAGGGAAATCCGTCGGTGGT
TCCCTCGTCGAAGACGACAAAATTGATTTGGCAAAGAGCTTAATGGAAAAGGCCCAGGGGAAAATTTTGCTGCCCACTGA
CGTGATTGTCGCAGACAAGTTTGCCCCCGATGCTGAAGCTAAAACTGTCAGCGTTGACGCAATTCCCGACGGCTGGATGG
GTCTCGACATTGGTGCTGATTCTGTGAAGGTCTTCCAAGAAGCTCTTGATGGCTGTGGTACAGCGATCTGGAATGGCCCA
ATGGGGGTATTCGAGTTCGATAAATTTGCCGTGGGTACCGAGGCGATCGCCAAGACCCTTGCTGGTGCGACTGAAACTGG
TACGGTCACGATTATTGGGGGTGGAGACTCCGTTGCGGCCGTCGAAAAAGTTGGTGTTGCAGACAAAATGAGTCACATTT
CCACAGGTGGTGGTGCCAGCCTCGAACTGCTCGAAGGAAAAGAGCTTCCCGGTATTGTTGCCCTCGATGATGCCTAA

Upstream 100 bases:

>100_bases
GATTTGGAACTTCTAGTTCAATTTTCTCGGAAAAATGGTCTTCTTCTGATGACAAGATGACAGAACTTTATAAAAAGCAA
GCATTTGGAGGATCCTAATT

Downstream 100 bases:

>100_bases
ACTTTTAACCGTTCTTTTGCTCTAACAAATACCCCCCTAGCTCAATTTAGGGGGGCTTTTTTACAAAGAATTTTCCGAGA
ATGTTAAGCCTGTGGGACAT

Product: phosphoglycerate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MAKKSVANLTEADLSGKRVFVRVDFNVPLNESGVITDDTRIRAALPTIKYLTEKGAKVILGSHMGRPKGQVVDSMRLTPV
AARLSELLGQSVTKCDDCVGDAVNQAIANLGNGQVALLENLRFNPGEEKNDPEFAKQLAANADIYVNDAFGTAHRAHGST
EGVTHHVDTSVAGLLIEKELQFLKGAIEAPKRPLVAIVGGSKVSSKIGVIETLLEKCDKLLIGGGMIFTFYKAQGKSVGG
SLVEDDKIDLAKSLMEKAQGKILLPTDVIVADKFAPDAEAKTVSVDAIPDGWMGLDIGADSVKVFQEALDGCGTAIWNGP
MGVFEFDKFAVGTEAIAKTLAGATETGTVTIIGGGDSVAAVEKVGVADKMSHISTGGGASLELLEGKELPGIVALDDA

Sequences:

>Translated_398_residues
MAKKSVANLTEADLSGKRVFVRVDFNVPLNESGVITDDTRIRAALPTIKYLTEKGAKVILGSHMGRPKGQVVDSMRLTPV
AARLSELLGQSVTKCDDCVGDAVNQAIANLGNGQVALLENLRFNPGEEKNDPEFAKQLAANADIYVNDAFGTAHRAHGST
EGVTHHVDTSVAGLLIEKELQFLKGAIEAPKRPLVAIVGGSKVSSKIGVIETLLEKCDKLLIGGGMIFTFYKAQGKSVGG
SLVEDDKIDLAKSLMEKAQGKILLPTDVIVADKFAPDAEAKTVSVDAIPDGWMGLDIGADSVKVFQEALDGCGTAIWNGP
MGVFEFDKFAVGTEAIAKTLAGATETGTVTIIGGGDSVAAVEKVGVADKMSHISTGGGASLELLEGKELPGIVALDDA
>Mature_397_residues
AKKSVANLTEADLSGKRVFVRVDFNVPLNESGVITDDTRIRAALPTIKYLTEKGAKVILGSHMGRPKGQVVDSMRLTPVA
ARLSELLGQSVTKCDDCVGDAVNQAIANLGNGQVALLENLRFNPGEEKNDPEFAKQLAANADIYVNDAFGTAHRAHGSTE
GVTHHVDTSVAGLLIEKELQFLKGAIEAPKRPLVAIVGGSKVSSKIGVIETLLEKCDKLLIGGGMIFTFYKAQGKSVGGS
LVEDDKIDLAKSLMEKAQGKILLPTDVIVADKFAPDAEAKTVSVDAIPDGWMGLDIGADSVKVFQEALDGCGTAIWNGPM
GVFEFDKFAVGTEAIAKTLAGATETGTVTIIGGGDSVAAVEKVGVADKMSHISTGGGASLELLEGKELPGIVALDDA

Specific function: Second phase of glycolysis; second step. [C]

COG id: COG0126

COG function: function code G; 3-phosphoglycerate kinase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate kinase family

Homologues:

Organism=Homo sapiens, GI4505763, Length=411, Percent_Identity=46.7153284671533, Blast_Score=342, Evalue=3e-94,
Organism=Homo sapiens, GI31543397, Length=411, Percent_Identity=45.0121654501217, Blast_Score=331, Evalue=6e-91,
Organism=Escherichia coli, GI1789294, Length=394, Percent_Identity=45.4314720812183, Blast_Score=315, Evalue=4e-87,
Organism=Caenorhabditis elegans, GI17508823, Length=411, Percent_Identity=48.9051094890511, Blast_Score=365, Evalue=1e-101,
Organism=Saccharomyces cerevisiae, GI6319857, Length=417, Percent_Identity=47.0023980815348, Blast_Score=355, Evalue=5e-99,
Organism=Drosophila melanogaster, GI17136394, Length=417, Percent_Identity=47.0023980815348, Blast_Score=332, Evalue=3e-91,
Organism=Drosophila melanogaster, GI24581203, Length=413, Percent_Identity=45.0363196125908, Blast_Score=327, Evalue=1e-89,

Paralogues:

None

Copy number: 2990 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1460 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): PGK_SYNP2 (B1XNQ1)

Other databases:

- EMBL:   CP000951
- RefSeq:   YP_001734832.1
- ProteinModelPortal:   B1XNQ1
- SMR:   B1XNQ1
- GeneID:   6055077
- GenomeReviews:   CP000951_GR
- KEGG:   syp:SYNPCC7002_A1585
- HOGENOM:   HBG453500
- OMA:   DCIGDEV
- ProtClustDB:   PRK00073
- GO:   GO:0005737
- GO:   GO:0006096
- HAMAP:   MF_00145
- InterPro:   IPR001576
- InterPro:   IPR015901
- InterPro:   IPR015911
- InterPro:   IPR015824
- Gene3D:   G3DSA:3.40.50.1270
- Gene3D:   G3DSA:3.40.50.1260
- PANTHER:   PTHR11406
- PIRSF:   PIRSF000724
- PRINTS:   PR00477

Pfam domain/function: PF00162 PGK; SSF53748 PGK

EC number: =2.7.2.3

Molecular weight: Translated: 41554; Mature: 41423

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS00111 PGLYCERATE_KINASE

Important sites: BINDING 40-40 BINDING 122-122 BINDING 155-155 BINDING 206-206 BINDING 294-294 BINDING 325-325

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKKSVANLTEADLSGKRVFVRVDFNVPLNESGVITDDTRIRAALPTIKYLTEKGAKVIL
CCCCHHHCHHHCCCCCCEEEEEEECCCCCCCCCEEECCCHHHHHHHHHHHHHHCCCEEEE
GSHMGRPKGQVVDSMRLTPVAARLSELLGQSVTKCDDCVGDAVNQAIANLGNGQVALLEN
ECCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
LRFNPGEEKNDPEFAKQLAANADIYVNDAFGTAHRAHGSTEGVTHHVDTSVAGLLIEKEL
CCCCCCCCCCCHHHHHHHHCCCCEEEECCCCCHHHCCCCCCCCEEECCHHHHHHHHHHHH
QFLKGAIEAPKRPLVAIVGGSKVSSKIGVIETLLEKCDKLLIGGGMIFTFYKAQGKSVGG
HHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHEECCCEEEEEEECCCCCCCC
SLVEDDKIDLAKSLMEKAQGKILLPTDVIVADKFAPDAEAKTVSVDAIPDGWMGLDIGAD
CCCCCHHHHHHHHHHHHHCCCEECCCCEEEECCCCCCCCCCEEEEECCCCCCEEEECCCH
SVKVFQEALDGCGTAIWNGPMGVFEFDKFAVGTEAIAKTLAGATETGTVTIIGGGDSVAA
HHHHHHHHHHHCCHHHCCCCCCCEECHHHHCCHHHHHHHHCCCCCCCEEEEEECCCCCHH
VEKVGVADKMSHISTGGGASLELLEGKELPGIVALDDA
HHHHCCHHHHHHCCCCCCCEEEEECCCCCCCEEEECCC
>Mature Secondary Structure 
AKKSVANLTEADLSGKRVFVRVDFNVPLNESGVITDDTRIRAALPTIKYLTEKGAKVIL
CCCHHHCHHHCCCCCCEEEEEEECCCCCCCCCEEECCCHHHHHHHHHHHHHHCCCEEEE
GSHMGRPKGQVVDSMRLTPVAARLSELLGQSVTKCDDCVGDAVNQAIANLGNGQVALLEN
ECCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEC
LRFNPGEEKNDPEFAKQLAANADIYVNDAFGTAHRAHGSTEGVTHHVDTSVAGLLIEKEL
CCCCCCCCCCCHHHHHHHHCCCCEEEECCCCCHHHCCCCCCCCEEECCHHHHHHHHHHHH
QFLKGAIEAPKRPLVAIVGGSKVSSKIGVIETLLEKCDKLLIGGGMIFTFYKAQGKSVGG
HHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHEECCCEEEEEEECCCCCCCC
SLVEDDKIDLAKSLMEKAQGKILLPTDVIVADKFAPDAEAKTVSVDAIPDGWMGLDIGAD
CCCCCHHHHHHHHHHHHHCCCEECCCCEEEECCCCCCCCCCEEEEECCCCCCEEEECCCH
SVKVFQEALDGCGTAIWNGPMGVFEFDKFAVGTEAIAKTLAGATETGTVTIIGGGDSVAA
HHHHHHHHHHHCCHHHCCCCCCCEECHHHHCCHHHHHHHHCCCCCCCEEEEEECCCCCHH
VEKVGVADKMSHISTGGGASLELLEGKELPGIVALDDA
HHHHCCHHHHHHCCCCCCCEEEEECCCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA