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The map label for this gene is rfbM [H]

Identifier: 170078163

GI number: 170078163

Start: 1640168

End: 1641196

Strand: Direct

Name: rfbM [H]

Synonym: SYNPCC7002_A1554

Alternate gene names: 170078163

Gene position: 1640168-1641196 (Clockwise)

Preceding gene: 170078162

Following gene: 170078164

Centisome position: 54.53

GC content: 52.48

Gene sequence:

>1029_bases
ATGACTTTCATTCCCGTAATTTTGGCTGGTGGCAAGGGCGAACGTTTTTGGCCCCTCAGTCGTCAAGACCGCCCGAAACA
GTTCCTCAGCCTCGATGGGTCTGGGGTGAGTTTGCTGCAAGCGACAGCAAATCGTTTAGTTTCCCAGGACAATTGGACAG
ATCTCTGGGTGATTACGGCGGCGCAAATTGCGGATCTGGTGCGGGAACAACTGCCCCAACTGCCCCAGCGTAATATTTTG
GTAGAACCGGAACGGCGGGATACGGCCGCGGCGATCGCCTGGACTTGTTTAGAGTTGGCGCAATACTACCCAGAGGATAC
GGTCGTTGCTTTTTTCCCCGCGGATCATTGGATTGGCGACCCAGATAGATTCCGGGCAACCCTCGACCAGGCGGCGAATT
TTGTCAAAGATAAATTGGCGATCGCCACCATCGGCATCAAACCGGACTATCCCGCCACGGGTTACGGCTACATCGAGCAG
GGGGAAGCGGTTGAAACGGGCATTTTTAAGGTGAATCAGTTCTACGAAAAACCCGGTACGGCTGTGGCAAAATCCTTTTT
AGAAACGGGCAAATTTAGCTGGAATAGCGGGATTTTTCTCTTTTCGATCCGCACCGTCCTCCAGGAACTCGCCAGCTACG
CCCCGGAAATTCTGGAACCGCTCCAAAATGAAGGGATCGACGCTTACAATAGCTTGCCGAAAATTAGTATCGACTACGCT
CTAATGGAAAAAACCGAGCACGCCTATGTATTGCCCGCAGAATTCGGTTGGGATGATCTGGGGGATTGGCGATCGCTCGA
AAGATTGTTGCCCCCCGATGCGGTGACCAATGTGTGTGTGGGGAATCACCATGCCTTTGAGACGGAACGGGCGATTGTCT
ACAGTGACAACCCCGACGAAACAGTGGTAACTCTAGGAGTTGCAGACGTGGTGGTGGTGCGCCAGGGAGATGTGACCCTG
ATTGTGGATAAGCACCGCACCCAGGACATTAAAAAAATCCTCGGCTATCTCCCGAAAAATCTTTTGTAA

Upstream 100 bases:

>100_bases
TGGTTTGGCTTTTTATTTTTCTTGATCCCCTTTACCATTGCTGCTGTAACCTGGATTCGCGCTTCGGCGAAGGCCTACCG
TAATTAAGCACTCCCAACCT

Downstream 100 bases:

>100_bases
TGACTGGAGTTTGGCACTATATTCCGCCCATCGAAGCGTCTGGGGAAACCCAAATGGCGATTGATGCGTGGCTTTTGGAT
CAGCATCTCCAGGGCAAAAT

Product: mannose-1-phosphate guanylyltransferase

Products: NA

Alternate protein names: GDP-mannose pyrophosphorylase; GMP; GMPP; GTP--mannose-1-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MTFIPVILAGGKGERFWPLSRQDRPKQFLSLDGSGVSLLQATANRLVSQDNWTDLWVITAAQIADLVREQLPQLPQRNIL
VEPERRDTAAAIAWTCLELAQYYPEDTVVAFFPADHWIGDPDRFRATLDQAANFVKDKLAIATIGIKPDYPATGYGYIEQ
GEAVETGIFKVNQFYEKPGTAVAKSFLETGKFSWNSGIFLFSIRTVLQELASYAPEILEPLQNEGIDAYNSLPKISIDYA
LMEKTEHAYVLPAEFGWDDLGDWRSLERLLPPDAVTNVCVGNHHAFETERAIVYSDNPDETVVTLGVADVVVVRQGDVTL
IVDKHRTQDIKKILGYLPKNLL

Sequences:

>Translated_342_residues
MTFIPVILAGGKGERFWPLSRQDRPKQFLSLDGSGVSLLQATANRLVSQDNWTDLWVITAAQIADLVREQLPQLPQRNIL
VEPERRDTAAAIAWTCLELAQYYPEDTVVAFFPADHWIGDPDRFRATLDQAANFVKDKLAIATIGIKPDYPATGYGYIEQ
GEAVETGIFKVNQFYEKPGTAVAKSFLETGKFSWNSGIFLFSIRTVLQELASYAPEILEPLQNEGIDAYNSLPKISIDYA
LMEKTEHAYVLPAEFGWDDLGDWRSLERLLPPDAVTNVCVGNHHAFETERAIVYSDNPDETVVTLGVADVVVVRQGDVTL
IVDKHRTQDIKKILGYLPKNLL
>Mature_341_residues
TFIPVILAGGKGERFWPLSRQDRPKQFLSLDGSGVSLLQATANRLVSQDNWTDLWVITAAQIADLVREQLPQLPQRNILV
EPERRDTAAAIAWTCLELAQYYPEDTVVAFFPADHWIGDPDRFRATLDQAANFVKDKLAIATIGIKPDYPATGYGYIEQG
EAVETGIFKVNQFYEKPGTAVAKSFLETGKFSWNSGIFLFSIRTVLQELASYAPEILEPLQNEGIDAYNSLPKISIDYAL
MEKTEHAYVLPAEFGWDDLGDWRSLERLLPPDAVTNVCVGNHHAFETERAIVYSDNPDETVVTLGVADVVVVRQGDVTLI
VDKHRTQDIKKILGYLPKNLL

Specific function: Involved in GDP-mannose biosynthesis which serves as the activated sugar nucleotide precursor for mannose residues in cell surface polysaccharides. This enzyme participates in synthesis of the LPS group C2 O antigen [H]

COG id: COG0836

COG function: function code M; Mannose-1-phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannose-6-phosphate isomerase type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1788362, Length=351, Percent_Identity=40.1709401709402, Blast_Score=218, Evalue=4e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR006375
- InterPro:   IPR001538
- InterPro:   IPR005835
- InterPro:   IPR014710 [H]

Pfam domain/function: PF01050 MannoseP_isomer; PF00483 NTP_transferase [H]

EC number: =2.7.7.13 [H]

Molecular weight: Translated: 38271; Mature: 38140

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFIPVILAGGKGERFWPLSRQDRPKQFLSLDGSGVSLLQATANRLVSQDNWTDLWVITA
CCEEEEEEECCCCCEECCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEEEEHH
AQIADLVREQLPQLPQRNILVEPERRDTAAAIAWTCLELAQYYPEDTVVAFFPADHWIGD
HHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCC
PDRFRATLDQAANFVKDKLAIATIGIKPDYPATGYGYIEQGEAVETGIFKVNQFYEKPGT
HHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCH
AVAKSFLETGKFSWNSGIFLFSIRTVLQELASYAPEILEPLQNEGIDAYNSLPKISIDYA
HHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCEEEHHH
LMEKTEHAYVLPAEFGWDDLGDWRSLERLLPPDAVTNVCVGNHHAFETERAIVYSDNPDE
HHHCCCCCEEEECCCCCCCCCHHHHHHHHCCCHHHHHHHCCCCCCCCCCCEEEECCCCCC
TVVTLGVADVVVVRQGDVTLIVDKHRTQDIKKILGYLPKNLL
EEEEEEEEEEEEEECCCEEEEEECCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TFIPVILAGGKGERFWPLSRQDRPKQFLSLDGSGVSLLQATANRLVSQDNWTDLWVITA
CEEEEEEECCCCCEECCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEEEEHH
AQIADLVREQLPQLPQRNILVEPERRDTAAAIAWTCLELAQYYPEDTVVAFFPADHWIGD
HHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCC
PDRFRATLDQAANFVKDKLAIATIGIKPDYPATGYGYIEQGEAVETGIFKVNQFYEKPGT
HHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCH
AVAKSFLETGKFSWNSGIFLFSIRTVLQELASYAPEILEPLQNEGIDAYNSLPKISIDYA
HHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCEEEHHH
LMEKTEHAYVLPAEFGWDDLGDWRSLERLLPPDAVTNVCVGNHHAFETERAIVYSDNPDE
HHHCCCCCEEEECCCCCCCCCHHHHHHHHCCCHHHHHHHCCCCCCCCCCCEEEECCCCCC
TVVTLGVADVVVVRQGDVTLIVDKHRTQDIKKILGYLPKNLL
EEEEEEEEEEEEEECCCEEEEEECCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1379320 [H]