Click here to switch to the map view.

The map label for this gene is lepB [H]

Identifier: 170078044

GI number: 170078044

Start: 1507076

End: 1507702

Strand: Direct

Name: lepB [H]

Synonym: SYNPCC7002_A1435

Alternate gene names: 170078044

Gene position: 1507076-1507702 (Clockwise)

Preceding gene: 170078043

Following gene: 170078045

Centisome position: 50.1

GC content: 50.4

Gene sequence:

>627_bases
ATGCCCGAAAACTCTCAATTTCCCGTTGAACCGACCCAGAAACCCAGTGGCACGGAGCAACAGCATGAAGAAAATCCCTG
GGTAGAGACCATCAAGACCCTTGTGACCGCTGGTATTTTGGCCATTGGGATCCGCACCTTCGTCGCCGAGGCCCGCTACA
TTCCTTCCGAGTCGATGCTGCCGACCCTAGAAGTGAACGATCGCCTAATCATTGAAAAAATTAGCTATCACTTCAAAAAT
CCCCAACGGGGCGATGTGGTGGTCTTTAACCCGACAGAAATTCTCCAGCAGCAAAACTATCGGGATGCTTTTATTAAACG
GGTGATCGGGATTCCTGGTGATACCGTACAAGTCAGCGGCGGCACCGTTTTTATCAATGGGGAAGCCCTCGAAGAAGACT
ATATCAACGAAGCCCCAGAATATGACTACGGCCCCGTGACGATTCCAGAAGATCACTACCTCGTCCTTGGCGATAACCGC
AACAATAGCTATGACTCCCACTATTGGGGTTTTGTCCCCCGTGAAAAGCTTGTGGGGAAAGCCTTTATTCGTTTTTGGCC
CTTTAATCGTGTGGGCATCCTCAACGAAGAGCCGCAATTTGCCGACGAAGAACCGATTACACCCTAG

Upstream 100 bases:

>100_bases
AGCATCAGCACTTTTTCTCAGGCAGGCACAATTGTCGTCACCATCACGTCGTGCATTCTGCCGCACAATTTTCTTTTAGT
CACTTCTGCGCGAACCGATA

Downstream 100 bases:

>100_bases
CGTCCCATCCCAGAGACCGCTAGGATATAGGGCGACTCCCTATCCCGGCAACCATGAGTGAACCATCCCCTTTGCTGCAA
GCATCAGGTCTCCATAAAAG

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I-2; Leader peptidase I-2 [H]

Number of amino acids: Translated: 208; Mature: 207

Protein sequence:

>208_residues
MPENSQFPVEPTQKPSGTEQQHEENPWVETIKTLVTAGILAIGIRTFVAEARYIPSESMLPTLEVNDRLIIEKISYHFKN
PQRGDVVVFNPTEILQQQNYRDAFIKRVIGIPGDTVQVSGGTVFINGEALEEDYINEAPEYDYGPVTIPEDHYLVLGDNR
NNSYDSHYWGFVPREKLVGKAFIRFWPFNRVGILNEEPQFADEEPITP

Sequences:

>Translated_208_residues
MPENSQFPVEPTQKPSGTEQQHEENPWVETIKTLVTAGILAIGIRTFVAEARYIPSESMLPTLEVNDRLIIEKISYHFKN
PQRGDVVVFNPTEILQQQNYRDAFIKRVIGIPGDTVQVSGGTVFINGEALEEDYINEAPEYDYGPVTIPEDHYLVLGDNR
NNSYDSHYWGFVPREKLVGKAFIRFWPFNRVGILNEEPQFADEEPITP
>Mature_207_residues
PENSQFPVEPTQKPSGTEQQHEENPWVETIKTLVTAGILAIGIRTFVAEARYIPSESMLPTLEVNDRLIIEKISYHFKNP
QRGDVVVFNPTEILQQQNYRDAFIKRVIGIPGDTVQVSGGTVFINGEALEEDYINEAPEYDYGPVTIPEDHYLVLGDNRN
NSYDSHYWGFVPREKLVGKAFIRFWPFNRVGILNEEPQFADEEPITP

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

Organism=Homo sapiens, GI21450679, Length=169, Percent_Identity=26.6272189349112, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1788921, Length=102, Percent_Identity=34.3137254901961, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 23754; Mature: 23623

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: PS00501 SPASE_I_1 ; PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPENSQFPVEPTQKPSGTEQQHEENPWVETIKTLVTAGILAIGIRTFVAEARYIPSESML
CCCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PTLEVNDRLIIEKISYHFKNPQRGDVVVFNPTEILQQQNYRDAFIKRVIGIPGDTVQVSG
CEEECCCEEEEEEHHHHCCCCCCCCEEEECHHHHHHCCCHHHHHHHHHHCCCCCEEEECC
GTVFINGEALEEDYINEAPEYDYGPVTIPEDHYLVLGDNRNNSYDSHYWGFVPREKLVGK
CEEEEECCHHHHHHHCCCCCCCCCCEECCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHH
AFIRFWPFNRVGILNEEPQFADEEPITP
HHHHHCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PENSQFPVEPTQKPSGTEQQHEENPWVETIKTLVTAGILAIGIRTFVAEARYIPSESML
CCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PTLEVNDRLIIEKISYHFKNPQRGDVVVFNPTEILQQQNYRDAFIKRVIGIPGDTVQVSG
CEEECCCEEEEEEHHHHCCCCCCCCEEEECHHHHHHCCCHHHHHHHHHHCCCCCEEEECC
GTVFINGEALEEDYINEAPEYDYGPVTIPEDHYLVLGDNRNNSYDSHYWGFVPREKLVGK
CEEEEECCHHHHHHHCCCCCCCCCCEECCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHH
AFIRFWPFNRVGILNEEPQFADEEPITP
HHHHHCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]