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The map label for this gene is 170078034

Identifier: 170078034

GI number: 170078034

Start: 1498139

End: 1499617

Strand: Direct

Name: 170078034

Synonym: SYNPCC7002_A1425

Alternate gene names: NA

Gene position: 1498139-1499617 (Clockwise)

Preceding gene: 170078033

Following gene: 170078038

Centisome position: 49.8

GC content: 48.41

Gene sequence:

>1479_bases
ATGACTTCCATCTTTCCAAACAAAACGAAATCTTACAATCAAGCCGCGTGGCAAAAAGGCTATGAATCCCAGCGACAGGA
ACTTGCCTATGAAGTCACAGATATTGACGGCGAGATCCCTGTCGAATTGATGGGAACCTTGTTTCGTAACGGGCCTGGGC
TCTTAGACATTGGTGGCATGCCGATTAAGCATCCTTTCGATGGTGATGGAATGGTCTGCTCAGTCAGCTTTCAGGAAGGG
CGGGCCTATTTCCAGAATCGCTTTGTGCAGACAGCAGGGTTTGTGGCGGAACAAAAAGCTGGTCAACCTATTTATCGAGG
CGTATTTGGAACGCAAAAACCGGGCGGTATTTTCAATAATATGTTTGACTTGCGGTTGAAAAATATCGCAAACACAAACG
TGATCTATTGGGGGAAAAAACTGTTAGCCCTCTGGGAAGCGGCAGAACCCCACAGTTTAAATCCTGAAAATTTGGAAACG
CGCGGCCTGGATTATTTAGGGGAAACGCTCAAGCCTGGGGATAGTTTTTCGGCCCATCCACGTATTGATCCGGCGAGTAT
TTGGGATGGGGGCGAACCTTGTTTGGTGAATTTTGCGGTAAAACCAGGTCTTCCGACGCGCTTGGTGATCTATGAAATTA
GTCCGGCAGGCAAATTACTGCGCTATCGAGAACATGAAGCTAAAGGCTTTGCATTTATCCATGATTTCGTGATTACGCCC
AATTACGTCATTTTTTTCCAAGCGTCGGTGAAATTTAATCCTTTGCCCTATGTTTTGGGGTTTAAGGGGGCCGGTGAATG
TGTGAAGTTTGAGGCGGATAAACCGACGCAGATGATCGTCATTCCGAGGGATCCGGCACGGGATGATGTACAAACGTTAG
AGGCGGAGGCGGGTTTTGTGTTTCACCATGCCAATGCCTTTGAGCAGGATAAACGAATTATCGTGGATTCGGTCTGCTAT
CAGTCAATCCCCCAGGTGCAGGCAGATGTGGATTATAAAAATGTTGATTTTGAGACTTTAGATCCGGGGCAGTTATGGCG
CTTTACTCTAGATTTAGAGACAAAAAAGGTGACGCGAGAACTATTGGCTACCCGCTGTTGTGAATTCCCGGTGGTGCATC
CAGAGCGTGTGGGACGGGACTATCGTTATGCCTACATCGGGGCGACCCACGCCAAAACAGGCAATGCACCGTTGCAGGCG
GTGTGGAAGGTGGATCACCAAGGGGAGGATTCTCAAGTTTATTCCTTTGCGCCAGACGGATTTACGGGGGAGCCGATTTT
TGTACCCCGTCCAGGAGCTACGGCAGAGGATGAAGGCTGGGTTCTCTTGATGGTCTATGATTCGGCCCAGCATCGCTCGG
ATGTGGTGATTTTTGATGCGCAAAATTTTGCTCAACCTTTGGCAACCCTACATTTAAAGCAGCATATTCCCTATGGCCTG
CATGGTAGTTGGACGCCGGAAGTGTTTGTGAATTTCTAG

Upstream 100 bases:

>100_bases
ACTGGATTTCTAAAGAGCTAAACTAGCCTTACCTGCATTATTTGATTAGTGTTAGACTTAGAATGAACTTAATAAAAGTT
AATAAAACCTGTTCTAGGGT

Downstream 100 bases:

>100_bases
TCGACCGATTCTTTGGGGTCAGGCGATCGCCAAATCCACCAGGCCCCTAAACACAGGGTGCAGTTACCCAGGAGAGTGAG
GGCGGCTTGGATCGTGACGA

Product: lignostilbene-alpha,beta-dioxygenase

Products: NA

Alternate protein names: ACO; 8'-apo-beta-carotenal 15,15'-oxygenase; Diox1 [H]

Number of amino acids: Translated: 492; Mature: 491

Protein sequence:

>492_residues
MTSIFPNKTKSYNQAAWQKGYESQRQELAYEVTDIDGEIPVELMGTLFRNGPGLLDIGGMPIKHPFDGDGMVCSVSFQEG
RAYFQNRFVQTAGFVAEQKAGQPIYRGVFGTQKPGGIFNNMFDLRLKNIANTNVIYWGKKLLALWEAAEPHSLNPENLET
RGLDYLGETLKPGDSFSAHPRIDPASIWDGGEPCLVNFAVKPGLPTRLVIYEISPAGKLLRYREHEAKGFAFIHDFVITP
NYVIFFQASVKFNPLPYVLGFKGAGECVKFEADKPTQMIVIPRDPARDDVQTLEAEAGFVFHHANAFEQDKRIIVDSVCY
QSIPQVQADVDYKNVDFETLDPGQLWRFTLDLETKKVTRELLATRCCEFPVVHPERVGRDYRYAYIGATHAKTGNAPLQA
VWKVDHQGEDSQVYSFAPDGFTGEPIFVPRPGATAEDEGWVLLMVYDSAQHRSDVVIFDAQNFAQPLATLHLKQHIPYGL
HGSWTPEVFVNF

Sequences:

>Translated_492_residues
MTSIFPNKTKSYNQAAWQKGYESQRQELAYEVTDIDGEIPVELMGTLFRNGPGLLDIGGMPIKHPFDGDGMVCSVSFQEG
RAYFQNRFVQTAGFVAEQKAGQPIYRGVFGTQKPGGIFNNMFDLRLKNIANTNVIYWGKKLLALWEAAEPHSLNPENLET
RGLDYLGETLKPGDSFSAHPRIDPASIWDGGEPCLVNFAVKPGLPTRLVIYEISPAGKLLRYREHEAKGFAFIHDFVITP
NYVIFFQASVKFNPLPYVLGFKGAGECVKFEADKPTQMIVIPRDPARDDVQTLEAEAGFVFHHANAFEQDKRIIVDSVCY
QSIPQVQADVDYKNVDFETLDPGQLWRFTLDLETKKVTRELLATRCCEFPVVHPERVGRDYRYAYIGATHAKTGNAPLQA
VWKVDHQGEDSQVYSFAPDGFTGEPIFVPRPGATAEDEGWVLLMVYDSAQHRSDVVIFDAQNFAQPLATLHLKQHIPYGL
HGSWTPEVFVNF
>Mature_491_residues
TSIFPNKTKSYNQAAWQKGYESQRQELAYEVTDIDGEIPVELMGTLFRNGPGLLDIGGMPIKHPFDGDGMVCSVSFQEGR
AYFQNRFVQTAGFVAEQKAGQPIYRGVFGTQKPGGIFNNMFDLRLKNIANTNVIYWGKKLLALWEAAEPHSLNPENLETR
GLDYLGETLKPGDSFSAHPRIDPASIWDGGEPCLVNFAVKPGLPTRLVIYEISPAGKLLRYREHEAKGFAFIHDFVITPN
YVIFFQASVKFNPLPYVLGFKGAGECVKFEADKPTQMIVIPRDPARDDVQTLEAEAGFVFHHANAFEQDKRIIVDSVCYQ
SIPQVQADVDYKNVDFETLDPGQLWRFTLDLETKKVTRELLATRCCEFPVVHPERVGRDYRYAYIGATHAKTGNAPLQAV
WKVDHQGEDSQVYSFAPDGFTGEPIFVPRPGATAEDEGWVLLMVYDSAQHRSDVVIFDAQNFAQPLATLHLKQHIPYGLH
GSWTPEVFVNF

Specific function: Cleaves a number of carotenals and carotenols in the all-trans configuration at the 15-15' double bond producing retinal or retinol, respectively. Also shows activity toward lycopenals and the corresponding alcohols. Does not cleave beta- carotene or lyco

COG id: COG3670

COG function: function code Q; Lignostilbene-alpha,beta-dioxygenase and related enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carotenoid oxygenase family [H]

Homologues:

Organism=Homo sapiens, GI4506591, Length=529, Percent_Identity=24.3856332703214, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI74027270, Length=526, Percent_Identity=25.0950570342205, Blast_Score=119, Evalue=8e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004294 [H]

Pfam domain/function: PF03055 RPE65 [H]

EC number: =1.14.99.41 [H]

Molecular weight: Translated: 55281; Mature: 55150

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS00082 EXTRADIOL_DIOXYGENAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSIFPNKTKSYNQAAWQKGYESQRQELAYEVTDIDGEIPVELMGTLFRNGPGLLDIGGM
CCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHCCCCEEEECCC
PIKHPFDGDGMVCSVSFQEGRAYFQNRFVQTAGFVAEQKAGQPIYRGVFGTQKPGGIFNN
CCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCHHHH
MFDLRLKNIANTNVIYWGKKLLALWEAAEPHSLNPENLETRGLDYLGETLKPGDSFSAHP
HHHHHHHCCCCCCEEEECHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCC
RIDPASIWDGGEPCLVNFAVKPGLPTRLVIYEISPAGKLLRYREHEAKGFAFIHDFVITP
CCCHHHCCCCCCCEEEEEEECCCCCCEEEEEEECCCHHHHHHHHHCCCCEEEEEEEEECC
NYVIFFQASVKFNPLPYVLGFKGAGECVKFEADKPTQMIVIPRDPARDDVQTLEAEAGFV
CEEEEEEEEEEECCCCEEEEECCCCCEEEEECCCCEEEEEECCCCCCHHHHHHHHCCCEE
FHHANAFEQDKRIIVDSVCYQSIPQVQADVDYKNVDFETLDPGQLWRFTLDLETKKVTRE
EEECCCCCCCCEEEHHHHHHHCCCCCCCCCCCCCCCCEECCCCCEEEEEEECCHHHHHHH
LLATRCCEFPVVHPERVGRDYRYAYIGATHAKTGNAPLQAVWKVDHQGEDSQVYSFAPDG
HHHHHHCCCCCCCHHHCCCCEEEEEEEEECCCCCCCCEEEEEEECCCCCCCEEEEECCCC
FTGEPIFVPRPGATAEDEGWVLLMVYDSAQHRSDVVIFDAQNFAQPLATLHLKQHIPYGL
CCCCEEEEECCCCCCCCCCEEEEEEECCCCCCCCEEEEECHHHHHHHHHHHHHHCCCCCC
HGSWTPEVFVNF
CCCCCCCEEEEC
>Mature Secondary Structure 
TSIFPNKTKSYNQAAWQKGYESQRQELAYEVTDIDGEIPVELMGTLFRNGPGLLDIGGM
CCCCCCCCCCCHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHCCCCEEEECCC
PIKHPFDGDGMVCSVSFQEGRAYFQNRFVQTAGFVAEQKAGQPIYRGVFGTQKPGGIFNN
CCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCHHHH
MFDLRLKNIANTNVIYWGKKLLALWEAAEPHSLNPENLETRGLDYLGETLKPGDSFSAHP
HHHHHHHCCCCCCEEEECHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCC
RIDPASIWDGGEPCLVNFAVKPGLPTRLVIYEISPAGKLLRYREHEAKGFAFIHDFVITP
CCCHHHCCCCCCCEEEEEEECCCCCCEEEEEEECCCHHHHHHHHHCCCCEEEEEEEEECC
NYVIFFQASVKFNPLPYVLGFKGAGECVKFEADKPTQMIVIPRDPARDDVQTLEAEAGFV
CEEEEEEEEEEECCCCEEEEECCCCCEEEEECCCCEEEEEECCCCCCHHHHHHHHCCCEE
FHHANAFEQDKRIIVDSVCYQSIPQVQADVDYKNVDFETLDPGQLWRFTLDLETKKVTRE
EEECCCCCCCCEEEHHHHHHHCCCCCCCCCCCCCCCCEECCCCCEEEEEEECCHHHHHHH
LLATRCCEFPVVHPERVGRDYRYAYIGATHAKTGNAPLQAVWKVDHQGEDSQVYSFAPDG
HHHHHHCCCCCCCHHHCCCCEEEEEEEEECCCCCCCCEEEEEEECCCCCCCEEEEECCCC
FTGEPIFVPRPGATAEDEGWVLLMVYDSAQHRSDVVIFDAQNFAQPLATLHLKQHIPYGL
CCCCEEEEECCCCCCCCCCEEEEEEECCCCCCCCEEEEECHHHHHHHHHHHHHHCCCCCC
HGSWTPEVFVNF
CCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]