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The map label for this gene is cofG [H]

Identifier: 170078026

GI number: 170078026

Start: 1488776

End: 1489792

Strand: Reverse

Name: cofG [H]

Synonym: SYNPCC7002_A1417

Alternate gene names: 170078026

Gene position: 1489792-1488776 (Counterclockwise)

Preceding gene: 170078032

Following gene: 170078024

Centisome position: 49.53

GC content: 52.02

Gene sequence:

>1017_bases
ATGCTGGATCTGTCAAGGGTTGATCGCCCGGTAGGCGGCGGCAGTAACCAGGCAAACGCTGTTGTGACCTACAGTCCAGC
TTTCACCTTGGTGCCAACTTACGAATGTTTCAATCGCTGTTCATATTGCAATTTTCGTGTTGATCCAGGTCAGGATCGTT
GGTTGACCCTAGCGACTGCCCAAGCTCGTCTAGAAAATCTCTGGGGGCAAGGCGTCCGAGAAATTTTGATTTTGAGTGGA
GAGGTGCATCCGGCTTCAGGGCGGCGATCGCCTTTGATCCAGCTCATCTATGATTTGTGTCAGTTGGCCTTAGATTACGG
TTTTATTCCCCACACCAATGCTGGCCCCCTGAGTCGTACTGAAATGGAATTGTTAAGGGATGTAAATGGTTCCATGGGGC
TGATGTTAGAACAAATGCGTCCGGATCTCCCCGTCCATCGTCGCGCCCCCAGCAAAGATCCCCAGGTGCGCCTACAACAA
TTGGTTCTAGCCGGAGAATTGAAAATCCCATTTACAACAGGGCTGCTGTTGGGAATCGGTGAAACGCCCCAGGATTGGCA
GGATACATTAGAGGCGATCGCCAAAATTCAGCATCAGTATGGTCACATCCAAGAGGTGATTTTGCAGCCCCACCGTCCTG
GGCAAACCCAGGACTATTTAGGTGAAGCCTTTTTGCCTGAGCAACTCCCAGCGGTTATTCAATTGGCCCGTGACATTTTG
CCACCGGAGATCACGATCCAAATTCCTCCTAATCTTGTGGCCGATCCCCAATGGCTTTTAGGTTGTCTCCAGGCTGGGGC
GAGGGATCTCGGCGGTATTGTCCCCAAGGATGAAGTCAATCCCGACTATTCCCATCTCCACCTCGATCAATTGCAACTCC
TCCTCGCTGATCAAGGCTGGCAATTACAACCCCGGCTCGCCGTTTATCCGGCCTATGATGGATGGCTAGCTTCCCAGGTG
AAACAGGTCGTTGAGCGCCATCGTCGAGCATTAACAGAGACCGAAGCCTTGTCCTGA

Upstream 100 bases:

>100_bases
CTATGAAATTATCAAGGTGCTTAACCTTAGTAGCTATATTAATGAAACTATTGCTTTTTGTAAAGTGTTTTAAGGAAATG
TTTTGATTTGCGGAGGGGCC

Downstream 100 bases:

>100_bases
AAAAAATCAGAAGAAAATTAGTCTGAAGTACGTTGTGGCCAGGGAATCGTCGAAACTTTAGCTAGTTCTTGGGCCACTTG
CGCCGCACCAAACTGATTGA

Product: FO synthase subunit 1

Products: NA

Alternate protein names: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit 1 [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MLDLSRVDRPVGGGSNQANAVVTYSPAFTLVPTYECFNRCSYCNFRVDPGQDRWLTLATAQARLENLWGQGVREILILSG
EVHPASGRRSPLIQLIYDLCQLALDYGFIPHTNAGPLSRTEMELLRDVNGSMGLMLEQMRPDLPVHRRAPSKDPQVRLQQ
LVLAGELKIPFTTGLLLGIGETPQDWQDTLEAIAKIQHQYGHIQEVILQPHRPGQTQDYLGEAFLPEQLPAVIQLARDIL
PPEITIQIPPNLVADPQWLLGCLQAGARDLGGIVPKDEVNPDYSHLHLDQLQLLLADQGWQLQPRLAVYPAYDGWLASQV
KQVVERHRRALTETEALS

Sequences:

>Translated_338_residues
MLDLSRVDRPVGGGSNQANAVVTYSPAFTLVPTYECFNRCSYCNFRVDPGQDRWLTLATAQARLENLWGQGVREILILSG
EVHPASGRRSPLIQLIYDLCQLALDYGFIPHTNAGPLSRTEMELLRDVNGSMGLMLEQMRPDLPVHRRAPSKDPQVRLQQ
LVLAGELKIPFTTGLLLGIGETPQDWQDTLEAIAKIQHQYGHIQEVILQPHRPGQTQDYLGEAFLPEQLPAVIQLARDIL
PPEITIQIPPNLVADPQWLLGCLQAGARDLGGIVPKDEVNPDYSHLHLDQLQLLLADQGWQLQPRLAVYPAYDGWLASQV
KQVVERHRRALTETEALS
>Mature_338_residues
MLDLSRVDRPVGGGSNQANAVVTYSPAFTLVPTYECFNRCSYCNFRVDPGQDRWLTLATAQARLENLWGQGVREILILSG
EVHPASGRRSPLIQLIYDLCQLALDYGFIPHTNAGPLSRTEMELLRDVNGSMGLMLEQMRPDLPVHRRAPSKDPQVRLQQ
LVLAGELKIPFTTGLLLGIGETPQDWQDTLEAIAKIQHQYGHIQEVILQPHRPGQTQDYLGEAFLPEQLPAVIQLARDIL
PPEITIQIPPNLVADPQWLLGCLQAGARDLGGIVPKDEVNPDYSHLHLDQLQLLLADQGWQLQPRLAVYPAYDGWLASQV
KQVVERHRRALTETEALS

Specific function: Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) [H]

COG id: COG1060

COG function: function code HR; Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. CofG family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006638
- InterPro:   IPR019939
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 37768; Mature: 37768

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDLSRVDRPVGGGSNQANAVVTYSPAFTLVPTYECFNRCSYCNFRVDPGQDRWLTLATA
CCCHHHHCCCCCCCCCCCCEEEEECCCEEEEECHHHHCCCCCCEEEECCCCCCEEEHHHH
QARLENLWGQGVREILILSGEVHPASGRRSPLIQLIYDLCQLALDYGFIPHTNAGPLSRT
HHHHHHHHHHHHHHHEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
EMELLRDVNGSMGLMLEQMRPDLPVHRRAPSKDPQVRLQQLVLAGELKIPFTTGLLLGIG
HHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHEEECC
ETPQDWQDTLEAIAKIQHQYGHIQEVILQPHRPGQTQDYLGEAFLPEQLPAVIQLARDIL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHCC
PPEITIQIPPNLVADPQWLLGCLQAGARDLGGIVPKDEVNPDYSHLHLDQLQLLLADQGW
CCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCC
QLQPRLAVYPAYDGWLASQVKQVVERHRRALTETEALS
CCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLDLSRVDRPVGGGSNQANAVVTYSPAFTLVPTYECFNRCSYCNFRVDPGQDRWLTLATA
CCCHHHHCCCCCCCCCCCCEEEEECCCEEEEECHHHHCCCCCCEEEECCCCCCEEEHHHH
QARLENLWGQGVREILILSGEVHPASGRRSPLIQLIYDLCQLALDYGFIPHTNAGPLSRT
HHHHHHHHHHHHHHHEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
EMELLRDVNGSMGLMLEQMRPDLPVHRRAPSKDPQVRLQQLVLAGELKIPFTTGLLLGIG
HHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHEEECC
ETPQDWQDTLEAIAKIQHQYGHIQEVILQPHRPGQTQDYLGEAFLPEQLPAVIQLARDIL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHCC
PPEITIQIPPNLVADPQWLLGCLQAGARDLGGIVPKDEVNPDYSHLHLDQLQLLLADQGW
CCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCC
QLQPRLAVYPAYDGWLASQVKQVVERHRRALTETEALS
CCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA