Click here to switch to the map view.

The map label for this gene is ruvB

Identifier: 170078004

GI number: 170078004

Start: 1455533

End: 1456624

Strand: Direct

Name: ruvB

Synonym: SYNPCC7002_A1390

Alternate gene names: 170078004

Gene position: 1455533-1456624 (Clockwise)

Preceding gene: 170078002

Following gene: 170078005

Centisome position: 48.39

GC content: 53.48

Gene sequence:

>1092_bases
ATGGCGATTAAACGCAACCAAGGCCATGGTCTCCCGCCTAAACGTGATCCGGCTTTGGGTAGAGATGCCCTCACCACGAG
TCAAGCCCTGCCCGAAGACCAGGAACAATCGGCCAATGAGGATCGCATTCGTCCCCAACGTCTGGGAGATTACCTGGGTC
AAAAGGATCTCAAGGAAGTATTGGGTATTGCGATCGCCGCTGCCAAAGCCCGCCGCGAACCCCTCGATCACATGTTGCTG
TATGGCCCCCCTGGGTTAGGGAAGACAACCATGTCCTTGATTTTAGCCGCAGAAATGGGGGTGAACTGTAAAATTACCGC
TGCCCCGGCCCTGGAACGCCCCCGTGATATTAGTGGCCTCTTGGTGGGCCTAGAGGCTGGCGACATTTTGTTTATCGATG
AAATCCACCGTCTCAATCGTATGGCCGAAGAATTGCTCTATCCAGCGATGGAAGATGGCCGCTTAGATGTCACCATTGGC
AAAGGAGTCAGTGCCAGAACCCGTAGTATTCCCCTGAAGCCTTTTACTTTGATTGGCGCGACAACCAAAGTGGGGGCATT
AACATCTCCCCTGCGCGATCGCTTTGGCTTGATTCAACGGTTACGTTTTTATGAGGTCGATGAATTGATTGCCATCGTCC
ATCGCAGTGCCTTGATCCTTGAGCAGCCCATTACCCCAGAGGGCGCTTTAGAGATTGCCCGTCGGGCGCGGGGGACGCCT
CGCATTGCCAACCGTCTGTTACGGCGAATCCGGGATTATGCCCAGGTCAAAGGCTATGGAGAAATTTCCCAAACGGTGGC
GGCAACGGCTTTGGATCTGTACAACGTTGATGCTTTGGGATTGGACTGGACAGATCGTCTAATCCTAGAAACCATGCTCA
ATCATTTTGGGGGTGGCCCGGTGGGTTTAGAGGCGATCGCCGCGGCTACTGGTGAGGACAGCAAGACCATTGAAGAGGTC
TACGAACCTTACTTACTCCAAATTGGCTTTTTAAATCGCACGCCCCGGGGACGGATAGTGAGCGCAAAAGCGAGACAGCA
TCTCGGTTTAATCCCGGTGGAACAAAGCACCCAACTCGACTTTTTACCCTAG

Upstream 100 bases:

>100_bases
TGGTCTTTATTTTACCGAAAGGTGTTCCTTTCCCTAAATGCCCGCATTTCCCAAAAGATTCAGTTTAGGATGGAGTGACA
GTTGTTTTCTGTCTACAGCA

Downstream 100 bases:

>100_bases
TTTTAACGAGTCTTGCGGGTGGCGGCCTCGAAATTTCTTTCTGGAGAAATCCTTCTAAAATAGGGAAAACACTTGAAATT
TGGACGATCAACGCAACTTT

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MAIKRNQGHGLPPKRDPALGRDALTTSQALPEDQEQSANEDRIRPQRLGDYLGQKDLKEVLGIAIAAAKARREPLDHMLL
YGPPGLGKTTMSLILAAEMGVNCKITAAPALERPRDISGLLVGLEAGDILFIDEIHRLNRMAEELLYPAMEDGRLDVTIG
KGVSARTRSIPLKPFTLIGATTKVGALTSPLRDRFGLIQRLRFYEVDELIAIVHRSALILEQPITPEGALEIARRARGTP
RIANRLLRRIRDYAQVKGYGEISQTVAATALDLYNVDALGLDWTDRLILETMLNHFGGGPVGLEAIAAATGEDSKTIEEV
YEPYLLQIGFLNRTPRGRIVSAKARQHLGLIPVEQSTQLDFLP

Sequences:

>Translated_363_residues
MAIKRNQGHGLPPKRDPALGRDALTTSQALPEDQEQSANEDRIRPQRLGDYLGQKDLKEVLGIAIAAAKARREPLDHMLL
YGPPGLGKTTMSLILAAEMGVNCKITAAPALERPRDISGLLVGLEAGDILFIDEIHRLNRMAEELLYPAMEDGRLDVTIG
KGVSARTRSIPLKPFTLIGATTKVGALTSPLRDRFGLIQRLRFYEVDELIAIVHRSALILEQPITPEGALEIARRARGTP
RIANRLLRRIRDYAQVKGYGEISQTVAATALDLYNVDALGLDWTDRLILETMLNHFGGGPVGLEAIAAATGEDSKTIEEV
YEPYLLQIGFLNRTPRGRIVSAKARQHLGLIPVEQSTQLDFLP
>Mature_362_residues
AIKRNQGHGLPPKRDPALGRDALTTSQALPEDQEQSANEDRIRPQRLGDYLGQKDLKEVLGIAIAAAKARREPLDHMLLY
GPPGLGKTTMSLILAAEMGVNCKITAAPALERPRDISGLLVGLEAGDILFIDEIHRLNRMAEELLYPAMEDGRLDVTIGK
GVSARTRSIPLKPFTLIGATTKVGALTSPLRDRFGLIQRLRFYEVDELIAIVHRSALILEQPITPEGALEIARRARGTPR
IANRLLRRIRDYAQVKGYGEISQTVAATALDLYNVDALGLDWTDRLILETMLNHFGGGPVGLEAIAAATGEDSKTIEEVY
EPYLLQIGFLNRTPRGRIVSAKARQHLGLIPVEQSTQLDFLP

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family

Homologues:

Organism=Escherichia coli, GI1788167, Length=331, Percent_Identity=55.5891238670695, Blast_Score=365, Evalue=1e-102,
Organism=Escherichia coli, GI1787119, Length=187, Percent_Identity=29.9465240641711, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVB_SYNP2 (B1XMA0)

Other databases:

- EMBL:   CP000951
- RefSeq:   YP_001734642.1
- ProteinModelPortal:   B1XMA0
- SMR:   B1XMA0
- GeneID:   6055813
- GenomeReviews:   CP000951_GR
- KEGG:   syp:SYNPCC7002_A1390
- HOGENOM:   HBG339960
- OMA:   EKFDGGP
- ProtClustDB:   PRK00080
- HAMAP:   MF_00016
- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- ProDom:   PD005323
- SMART:   SM00382
- TIGRFAMs:   TIGR00635

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N

EC number: =3.6.4.12

Molecular weight: Translated: 39865; Mature: 39733

Theoretical pI: Translated: 7.75; Mature: 7.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIKRNQGHGLPPKRDPALGRDALTTSQALPEDQEQSANEDRIRPQRLGDYLGQKDLKEV
CCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHCCCHHCCCHHHHHHHHCHHHHHHH
LGIAIAAAKARREPLDHMLLYGPPGLGKTTMSLILAAEMGVNCKITAAPALERPRDISGL
HHHHHHHHHHHHCCHHHEEEECCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCE
LVGLEAGDILFIDEIHRLNRMAEELLYPAMEDGRLDVTIGKGVSARTRSIPLKPFTLIGA
EEEECCCCEEEHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEECC
TTKVGALTSPLRDRFGLIQRLRFYEVDELIAIVHRSALILEQPITPEGALEIARRARGTP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCH
RIANRLLRRIRDYAQVKGYGEISQTVAATALDLYNVDALGLDWTDRLILETMLNHFGGGP
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCC
VGLEAIAAATGEDSKTIEEVYEPYLLQIGFLNRTPRGRIVSAKARQHLGLIPVEQSTQLD
HHHHHHHHHCCCCHHHHHHHHHHHEEEEECCCCCCCCCEEEHHHHHCCCCEECCCCCCCC
FLP
CCC
>Mature Secondary Structure 
AIKRNQGHGLPPKRDPALGRDALTTSQALPEDQEQSANEDRIRPQRLGDYLGQKDLKEV
CCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHCCCHHCCCHHHHHHHHCHHHHHHH
LGIAIAAAKARREPLDHMLLYGPPGLGKTTMSLILAAEMGVNCKITAAPALERPRDISGL
HHHHHHHHHHHHCCHHHEEEECCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCE
LVGLEAGDILFIDEIHRLNRMAEELLYPAMEDGRLDVTIGKGVSARTRSIPLKPFTLIGA
EEEECCCCEEEHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEECC
TTKVGALTSPLRDRFGLIQRLRFYEVDELIAIVHRSALILEQPITPEGALEIARRARGTP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCH
RIANRLLRRIRDYAQVKGYGEISQTVAATALDLYNVDALGLDWTDRLILETMLNHFGGGP
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCC
VGLEAIAAATGEDSKTIEEVYEPYLLQIGFLNRTPRGRIVSAKARQHLGLIPVEQSTQLD
HHHHHHHHHCCCCHHHHHHHHHHHEEEEECCCCCCCCCEEEHHHHHCCCCEECCCCCCCC
FLP
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA