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The map label for this gene is trpC [H]

Identifier: 170077962

GI number: 170077962

Start: 1403069

End: 1403959

Strand: Direct

Name: trpC [H]

Synonym: SYNPCC7002_A1348

Alternate gene names: 170077962

Gene position: 1403069-1403959 (Clockwise)

Preceding gene: 170077961

Following gene: 170077964

Centisome position: 46.64

GC content: 52.97

Gene sequence:

>891_bases
ATGACTGTGCAAATCCGTCGTCTCCACCCCAGCCGTCCCGTTAACGTCAGCATCTTGCAGTACCAAGTGGCGGTGCCCGA
TGCCAAACCCCAGCATATCCTGGAAGAAATTGTTTGGCATAAAGAAAAAGAAGTGGAGCAACTACGCGATAAGGTTTCTC
TGCTAGAGCTACGTCAGCGGGTCACAACGGTGCCGCCTGCAAAAGATTTTCTGGGGGCCTTAGTCCATGGGAAGACCCAG
CCAGCCCTCATCGCTGAAGTAAAAAAAGCCTCGCCTAGTAAGGGGGTAATTCGGGAAGATTTTGACCCTGTGGCGATCGC
CAAAAGTTATGCCGCCGGGGGAGCCAGTTGCCTCTCAGTCCTCACCGATAACAAGTTTTTCCAGGGCAGCTTCGAAAACC
TGAGCCTCGTGCGCGATGCGGTGGATCTGCCCCTGCTCTGCAAAGAATTTATTATTTATCCCTATCAAATCTTTAAGGCC
CGCAGCCATGGTGCCGATGCGGTTCTTTTGATCGCCGCGATCCTCAGTGACCAAGACCTCGCCTATTTCGTCAAAATTAT
CCGCAGCTTAGGGATGACCGCCCTGGTGGAAGTCCATACCCTCGCGGAACTTGATCGCGTCCTCGCCATTGAGGGGGTGA
GCCTCGTGGGGATTAATAACCGTAACCTCGAAGATTTTTCCGTCGATTTGGAAACAACCACCATATTGCTGGAAAGTCGT
CGCGCCGAACTCCAGGCTAAGGGTGTCCGCGTTGTCAGCGAGTCAGGCTTGCATACGCCCCTGGATCTCCAGTTTGTCAA
AGAAGCCGGAGCAAAGGCAGTGTTAATCGGCGAATCTCTCGTGAAACAGCTGGATCCTGGGAAGGCGATCGCCGACTTAT
TTCAGTTTTAG

Upstream 100 bases:

>100_bases
GAAGAAATAAGTCTTTATCTCTACTGCTTTTCGCGTAAATTACCCTTTGTTTTTGACAGGAGCAGCCCCTAGGGGTTGCT
TTTTCATCCCCAGCAAATCT

Downstream 100 bases:

>100_bases
ATTGGGCTAAACCTGGAGGGGCACTCCCGCCGTTGCCAGGTGTTTTTTGATGGTGACCTTGGGGATCGCCGTATTCAAAT
GCTGCCAGGGTAAGACCTGA

Product: indole-3-glycerol-phosphate synthase

Products: NA

Alternate protein names: IGPS [H]

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MTVQIRRLHPSRPVNVSILQYQVAVPDAKPQHILEEIVWHKEKEVEQLRDKVSLLELRQRVTTVPPAKDFLGALVHGKTQ
PALIAEVKKASPSKGVIREDFDPVAIAKSYAAGGASCLSVLTDNKFFQGSFENLSLVRDAVDLPLLCKEFIIYPYQIFKA
RSHGADAVLLIAAILSDQDLAYFVKIIRSLGMTALVEVHTLAELDRVLAIEGVSLVGINNRNLEDFSVDLETTTILLESR
RAELQAKGVRVVSESGLHTPLDLQFVKEAGAKAVLIGESLVKQLDPGKAIADLFQF

Sequences:

>Translated_296_residues
MTVQIRRLHPSRPVNVSILQYQVAVPDAKPQHILEEIVWHKEKEVEQLRDKVSLLELRQRVTTVPPAKDFLGALVHGKTQ
PALIAEVKKASPSKGVIREDFDPVAIAKSYAAGGASCLSVLTDNKFFQGSFENLSLVRDAVDLPLLCKEFIIYPYQIFKA
RSHGADAVLLIAAILSDQDLAYFVKIIRSLGMTALVEVHTLAELDRVLAIEGVSLVGINNRNLEDFSVDLETTTILLESR
RAELQAKGVRVVSESGLHTPLDLQFVKEAGAKAVLIGESLVKQLDPGKAIADLFQF
>Mature_295_residues
TVQIRRLHPSRPVNVSILQYQVAVPDAKPQHILEEIVWHKEKEVEQLRDKVSLLELRQRVTTVPPAKDFLGALVHGKTQP
ALIAEVKKASPSKGVIREDFDPVAIAKSYAAGGASCLSVLTDNKFFQGSFENLSLVRDAVDLPLLCKEFIIYPYQIFKAR
SHGADAVLLIAAILSDQDLAYFVKIIRSLGMTALVEVHTLAELDRVLAIEGVSLVGINNRNLEDFSVDLETTTILLESRR
AELQAKGVRVVSESGLHTPLDLQFVKEAGAKAVLIGESLVKQLDPGKAIADLFQF

Specific function: Bifunctional Enzyme That Catalyzes Two Sequential Steps Of Tryptophan Biosynthetic Pathway. The First Reaction Is Catalyzed By The Isomerase, Coded By The Trpf Domain; The Second Reaction Is Catalyzed By The Synthase, Coded By The Trpc Domain. [C]

COG id: COG0134

COG function: function code E; Indole-3-glycerol phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpC family [H]

Homologues:

Organism=Escherichia coli, GI87081863, Length=260, Percent_Identity=41.5384615384615, Blast_Score=159, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6322638, Length=239, Percent_Identity=41.0041841004184, Blast_Score=143, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR013798
- InterPro:   IPR001468
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00218 IGPS [H]

EC number: =4.1.1.48 [H]

Molecular weight: Translated: 32593; Mature: 32462

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS00614 IGPS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVQIRRLHPSRPVNVSILQYQVAVPDAKPQHILEEIVWHKEKEVEQLRDKVSLLELRQR
CEEEEEECCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
VTTVPPAKDFLGALVHGKTQPALIAEVKKASPSKGVIREDFDPVAIAKSYAAGGASCLSV
HCCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCHHCCCCHHHHHHHHCCCHHHHHHH
LTDNKFFQGSFENLSLVRDAVDLPLLCKEFIIYPYQIFKARSHGADAVLLIAAILSDQDL
HHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHH
AYFVKIIRSLGMTALVEVHTLAELDRVLAIEGVSLVGINNRNLEDFSVDLETTTILLESR
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCEEEEHHHHHEEHHHH
RAELQAKGVRVVSESGLHTPLDLQFVKEAGAKAVLIGESLVKQLDPGKAIADLFQF
HHHHHHCCEEEEECCCCCCCCHHHHHHHCCCCEEEECHHHHHHCCCCHHHHHHHCC
>Mature Secondary Structure 
TVQIRRLHPSRPVNVSILQYQVAVPDAKPQHILEEIVWHKEKEVEQLRDKVSLLELRQR
EEEEEECCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
VTTVPPAKDFLGALVHGKTQPALIAEVKKASPSKGVIREDFDPVAIAKSYAAGGASCLSV
HCCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCHHCCCCHHHHHHHHCCCHHHHHHH
LTDNKFFQGSFENLSLVRDAVDLPLLCKEFIIYPYQIFKARSHGADAVLLIAAILSDQDL
HHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHH
AYFVKIIRSLGMTALVEVHTLAELDRVLAIEGVSLVGINNRNLEDFSVDLETTTILLESR
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCEEEEHHHHHEEHHHH
RAELQAKGVRVVSESGLHTPLDLQFVKEAGAKAVLIGESLVKQLDPGKAIADLFQF
HHHHHHCCEEEEECCCCCCCCHHHHHHHCCCCEEEECHHHHHHCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA