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The map label for this gene is dapA [H]

Identifier: 170077889

GI number: 170077889

Start: 1320779

End: 1321669

Strand: Reverse

Name: dapA [H]

Synonym: SYNPCC7002_A1274

Alternate gene names: 170077889

Gene position: 1321669-1320779 (Counterclockwise)

Preceding gene: 170077890

Following gene: 170077888

Centisome position: 43.94

GC content: 54.43

Gene sequence:

>891_bases
ATGACAAGTACAAGATTTGGTCGAGTGATCACCGCAATGGTGACCCCCTTTACGGAAGAGGGGCAGGTGGATTACGCGAT
GGCGGAAAAATTAGCGGCCCATTTCATTGACCAGGGGAGTGACGCCCTTGTTGTCTGCGGCACCACCGGAGAATCGCCCA
CCCTGACTTGGGATGAGGAGTATGAGCTATTCCGGGCTGTGCAAAATGCTGCCACTGGACGGGCTAAGGTAATCGCGGGT
ACGGGTTCTAATTCCACCAGTGAGGCGATCGCCGCCACCCAAAAAGCCGCTAAACTGAACTTGGACGGTTCGCTGCAAGT
TGTTCCCTATTACAATAAGCCCCCCCAAGAAGGACTTTATCAGCATTTCAAGGCGATCGCCGAGGCCTGCCCTGATATCC
CATTGATGCTTTACAACGTGCCGGGGCGCACCAGTTGTAATCTGTTGCCCGAAACCGTGATTCGCCTCGCCACCGTGGAC
AACATCGTGGCCATCAAAGAAGCCAGCGGTAACCTCGACCAGGCCGCCCAAATTCGTTGTGGTGTAGATTCTACCTTTGA
AATTTACTCAGGGGATGATAGTCTAACTCTACCTTTGATGAGTGTAGGAGCCCAGGGCGTTGTGAGCGTGGCCAGTCACC
TTGTCGGGCCGCAGATGCAGGCGATGATCCAAGCCTTTCTTGCTGGCCGTACCCAAGAGGCGATCGCCCTCCACTTGAAG
CTTTTCCCCCTATTCCGTGTCCTATTCTGTGATACCAACCCCCTCCCCGTGAAAACCGCTCTCATTCTTCAGGGATGGCG
TTTAGGTAGCTTTCGTCCGCCCCTCTGTCCCCTCAGCCCTGATCGCACAAAACAACTCACCCAGGTGTTGAAGGATTTGT
CCCTCCTCTAA

Upstream 100 bases:

>100_bases
GATTGCGGAACTGCTTTGGGAAAAAGATTGGCTCCAACCAGCGGCGATCGCAACGGCGGTCTAGTCCAGTAAGATTTATG
TGTGTTGTGTCGATTCGTTT

Downstream 100 bases:

>100_bases
AACGAAGCATTCGGCGAACGTCCCACTGCCACGGCTTTTGACAACTGAACAGTATTGCGCCAATTACCAGCACCCTGTTG
CTCGCTGGTCATATCTAGCC

Product: dihydrodipicolinate synthase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MTSTRFGRVITAMVTPFTEEGQVDYAMAEKLAAHFIDQGSDALVVCGTTGESPTLTWDEEYELFRAVQNAATGRAKVIAG
TGSNSTSEAIAATQKAAKLNLDGSLQVVPYYNKPPQEGLYQHFKAIAEACPDIPLMLYNVPGRTSCNLLPETVIRLATVD
NIVAIKEASGNLDQAAQIRCGVDSTFEIYSGDDSLTLPLMSVGAQGVVSVASHLVGPQMQAMIQAFLAGRTQEAIALHLK
LFPLFRVLFCDTNPLPVKTALILQGWRLGSFRPPLCPLSPDRTKQLTQVLKDLSLL

Sequences:

>Translated_296_residues
MTSTRFGRVITAMVTPFTEEGQVDYAMAEKLAAHFIDQGSDALVVCGTTGESPTLTWDEEYELFRAVQNAATGRAKVIAG
TGSNSTSEAIAATQKAAKLNLDGSLQVVPYYNKPPQEGLYQHFKAIAEACPDIPLMLYNVPGRTSCNLLPETVIRLATVD
NIVAIKEASGNLDQAAQIRCGVDSTFEIYSGDDSLTLPLMSVGAQGVVSVASHLVGPQMQAMIQAFLAGRTQEAIALHLK
LFPLFRVLFCDTNPLPVKTALILQGWRLGSFRPPLCPLSPDRTKQLTQVLKDLSLL
>Mature_295_residues
TSTRFGRVITAMVTPFTEEGQVDYAMAEKLAAHFIDQGSDALVVCGTTGESPTLTWDEEYELFRAVQNAATGRAKVIAGT
GSNSTSEAIAATQKAAKLNLDGSLQVVPYYNKPPQEGLYQHFKAIAEACPDIPLMLYNVPGRTSCNLLPETVIRLATVDN
IVAIKEASGNLDQAAQIRCGVDSTFEIYSGDDSLTLPLMSVGAQGVVSVASHLVGPQMQAMIQAFLAGRTQEAIALHLKL
FPLFRVLFCDTNPLPVKTALILQGWRLGSFRPPLCPLSPDRTKQLTQVLKDLSLL

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=280, Percent_Identity=26.7857142857143, Blast_Score=91, Evalue=9e-19,
Organism=Homo sapiens, GI13540533, Length=226, Percent_Identity=25.6637168141593, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1788823, Length=292, Percent_Identity=44.5205479452055, Blast_Score=232, Evalue=3e-62,
Organism=Escherichia coli, GI1789620, Length=289, Percent_Identity=27.3356401384083, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI87082415, Length=247, Percent_Identity=28.7449392712551, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1786463, Length=290, Percent_Identity=28.6206896551724, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 31928; Mature: 31797

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS00665 DHDPS_1 ; PS00666 DHDPS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSTRFGRVITAMVTPFTEEGQVDYAMAEKLAAHFIDQGSDALVVCGTTGESPTLTWDEE
CCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEECCHH
YELFRAVQNAATGRAKVIAGTGSNSTSEAIAATQKAAKLNLDGSLQVVPYYNKPPQEGLY
HHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHEECCCCCEEEEECCCCCCHHHHH
QHFKAIAEACPDIPLMLYNVPGRTSCNLLPETVIRLATVDNIVAIKEASGNLDQAAQIRC
HHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCEEEEECCCCCCCCHHEEEE
GVDSTFEIYSGDDSLTLPLMSVGAQGVVSVASHLVGPQMQAMIQAFLAGRTQEAIALHLK
CCCCEEEEEECCCCEEEHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHH
LFPLFRVLFCDTNPLPVKTALILQGWRLGSFRPPLCPLSPDRTKQLTQVLKDLSLL
HHHHHHHHHCCCCCCCHHHEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TSTRFGRVITAMVTPFTEEGQVDYAMAEKLAAHFIDQGSDALVVCGTTGESPTLTWDEE
CCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEECCHH
YELFRAVQNAATGRAKVIAGTGSNSTSEAIAATQKAAKLNLDGSLQVVPYYNKPPQEGLY
HHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHEECCCCCEEEEECCCCCCHHHHH
QHFKAIAEACPDIPLMLYNVPGRTSCNLLPETVIRLATVDNIVAIKEASGNLDQAAQIRC
HHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCEEEEECCCCCCCCHHEEEE
GVDSTFEIYSGDDSLTLPLMSVGAQGVVSVASHLVGPQMQAMIQAFLAGRTQEAIALHLK
CCCCEEEEEECCCCEEEHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHH
LFPLFRVLFCDTNPLPVKTALILQGWRLGSFRPPLCPLSPDRTKQLTQVLKDLSLL
HHHHHHHHHCCCCCCCHHHEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA