Click here to switch to the map view.

The map label for this gene is dapL

Identifier: 170077820

GI number: 170077820

Start: 1248057

End: 1249289

Strand: Direct

Name: dapL

Synonym: SYNPCC7002_A1203

Alternate gene names: 170077820

Gene position: 1248057-1249289 (Clockwise)

Preceding gene: 170077818

Following gene: 170077824

Centisome position: 41.49

GC content: 49.47

Gene sequence:

>1233_bases
ATGGTTAGAATTAACGAAAATTACCTCAAACTTAAAGCAGGTTATCTCTTTCCCGAAATTGCCCGGCGAGTGAATGGGTT
TCTAGCAGAAAACCCCAATGCGCCCATTATCAAATTAGGGATTGGTGATGTCACCGAACCATTACCCGCTGCCTGTCGAG
AAGCGATGGCAAAGGCCATTGACGACATGGGCGATCGCGCCAACTTTAAAGGGTATGGCCCTGAACAAGGCTATGCTTGG
CTACGGGAAAAAATTGCCGCCCACGACTTCCAGGCCCGCGGTTGCGACATTGACGCCTCTGAAATTTTTGTGTCTGATGG
TGCCAAATGCGATACCGGGAACATCCTTGATATCTTTGGCAAAGACAATACCATCGCCGTCACTGACCCTGTTTACCCCG
TTTACGTTGATACCAACGTGATGGCAGGACATACCGGAGAAGCCGACGAGTCTGGTAAATATGGTGGCCTGACTTACATC
CCCATCACCGCTGACAATGACTTTGTCGCCCAAATCCCCACAGAAAAAGTCGATCTGATCTATCTCTGTTTTCCCAATAA
TCCCACCGGGGCAACGGCGACGAAAGAACAGCTCCAAGCTTGGGTGGATTATGCCAAGACCAATGGTTCAATTATTTTCT
TTGACGCTGCCTATGAAGCGTTCATTACCGACGAAAGCCTACCCCACTCGATCTACGAACTAGAAGGAGCGAAGGATTGC
GCCATCGAATTCCGTTCTTTCTCTAAAAATGCAGGCTTTACGGGGACTCGGTGTGCCTTTACCGTTGTGCCGAAAAATCT
GACTGTTACTGCGAGCAATGGCCAAGCCGTGCAACTCTGGAGCCTCTGGAACCGCCGTCAGTCCACCAAATTTAACGGCG
TTTCTTACATCGTCCAACGGGGAGCAGAGGCCGTTTATTCTGAAGCGGGTCAAGCCCAAATCAAAACACTGATCGATTTT
TACTTGGAAAATGCGGCCATTATTCGCCGGGAACTCCAAGCGGTTGGTTTTGATGTCTATGGCGGCGTGAATGCGCCCTA
TGTCTGGGTTAAAACCCCTGCTGGTTTATCGAGTTGGGACTTTTTTGACAAGCTCTTGATTAACTGCAATGTGGTCGGCA
CCCCAGGATCTGGTTTTGGGGCCGCTGGGGAAGGCTATTTCCGTATCTCTGCTTTCAATAGCCGTGAAAATGTGCTCGAA
GCAATGAAACGGATCACAACGGCATTCCAATAG

Upstream 100 bases:

>100_bases
AATTTTTCCGGCCTCTTCACCCCAAAAAGATCTAGCGGCTTCCCTGGGGCATGGGATGATAGGTTAAGCTGTCTTACGGT
CTTTTGCCCCTGATTTTTCT

Downstream 100 bases:

>100_bases
GGATTTAGTAATTTCTAAACGTTGAGTTAAAAAATTTGCTGTTGATCTTTTGAGGCGCACCGGAGTGCGTCTTTTTTTAT
GACCTTTACTAAGACGCGGG

Product: L,L-diaminopimelate aminotransferase

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MVRINENYLKLKAGYLFPEIARRVNGFLAENPNAPIIKLGIGDVTEPLPAACREAMAKAIDDMGDRANFKGYGPEQGYAW
LREKIAAHDFQARGCDIDASEIFVSDGAKCDTGNILDIFGKDNTIAVTDPVYPVYVDTNVMAGHTGEADESGKYGGLTYI
PITADNDFVAQIPTEKVDLIYLCFPNNPTGATATKEQLQAWVDYAKTNGSIIFFDAAYEAFITDESLPHSIYELEGAKDC
AIEFRSFSKNAGFTGTRCAFTVVPKNLTVTASNGQAVQLWSLWNRRQSTKFNGVSYIVQRGAEAVYSEAGQAQIKTLIDF
YLENAAIIRRELQAVGFDVYGGVNAPYVWVKTPAGLSSWDFFDKLLINCNVVGTPGSGFGAAGEGYFRISAFNSRENVLE
AMKRITTAFQ

Sequences:

>Translated_410_residues
MVRINENYLKLKAGYLFPEIARRVNGFLAENPNAPIIKLGIGDVTEPLPAACREAMAKAIDDMGDRANFKGYGPEQGYAW
LREKIAAHDFQARGCDIDASEIFVSDGAKCDTGNILDIFGKDNTIAVTDPVYPVYVDTNVMAGHTGEADESGKYGGLTYI
PITADNDFVAQIPTEKVDLIYLCFPNNPTGATATKEQLQAWVDYAKTNGSIIFFDAAYEAFITDESLPHSIYELEGAKDC
AIEFRSFSKNAGFTGTRCAFTVVPKNLTVTASNGQAVQLWSLWNRRQSTKFNGVSYIVQRGAEAVYSEAGQAQIKTLIDF
YLENAAIIRRELQAVGFDVYGGVNAPYVWVKTPAGLSSWDFFDKLLINCNVVGTPGSGFGAAGEGYFRISAFNSRENVLE
AMKRITTAFQ
>Mature_410_residues
MVRINENYLKLKAGYLFPEIARRVNGFLAENPNAPIIKLGIGDVTEPLPAACREAMAKAIDDMGDRANFKGYGPEQGYAW
LREKIAAHDFQARGCDIDASEIFVSDGAKCDTGNILDIFGKDNTIAVTDPVYPVYVDTNVMAGHTGEADESGKYGGLTYI
PITADNDFVAQIPTEKVDLIYLCFPNNPTGATATKEQLQAWVDYAKTNGSIIFFDAAYEAFITDESLPHSIYELEGAKDC
AIEFRSFSKNAGFTGTRCAFTVVPKNLTVTASNGQAVQLWSLWNRRQSTKFNGVSYIVQRGAEAVYSEAGQAQIKTLIDF
YLENAAIIRRELQAVGFDVYGGVNAPYVWVKTPAGLSSWDFFDKLLINCNVVGTPGSGFGAAGEGYFRISAFNSRENVLE
AMKRITTAFQ

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily

Homologues:

Organism=Escherichia coli, GI1788722, Length=359, Percent_Identity=25.9052924791086, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1788627, Length=236, Percent_Identity=27.9661016949153, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPAT_SYNP2 (B1XKF6)

Other databases:

- EMBL:   CP000951
- RefSeq:   YP_001734458.1
- ProteinModelPortal:   B1XKF6
- SMR:   B1XKF6
- GeneID:   6055982
- GenomeReviews:   CP000951_GR
- KEGG:   syp:SYNPCC7002_A1203
- HOGENOM:   HBG645860
- OMA:   VDLIYLC
- ProtClustDB:   PRK07590
- HAMAP:   MF_01642
- InterPro:   IPR004839
- InterPro:   IPR019942
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- Gene3D:   G3DSA:3.40.640.10
- Gene3D:   G3DSA:3.90.1150.10
- TIGRFAMs:   TIGR03542

Pfam domain/function: PF00155 Aminotran_1_2; SSF53383 PyrdxlP-dep_Trfase_major

EC number: =2.6.1.83

Molecular weight: Translated: 44879; Mature: 44879

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: BINDING 42-42 BINDING 72-72 BINDING 75-75 BINDING 109-109 BINDING 132-132 BINDING 187-187 BINDING 187-187 BINDING 215-215 BINDING 218-218 BINDING 246-246 BINDING 248-248 BINDING 257-257 BINDING 292-292 BINDING 388-388

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRINENYLKLKAGYLFPEIARRVNGFLAENPNAPIIKLGIGDVTEPLPAACREAMAKAI
CEEECCCEEEEEECCCCHHHHHHHCCCEECCCCCCEEEECCCCCCCHHHHHHHHHHHHHH
DDMGDRANFKGYGPEQGYAWLREKIAAHDFQARGCDIDASEIFVSDGAKCDTGNILDIFG
HHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHEEEECCCCCCCCCEEEEEC
KDNTIAVTDPVYPVYVDTNVMAGHTGEADESGKYGGLTYIPITADNDFVAQIPTEKVDLI
CCCEEEEECCEEEEEEECCEEECCCCCCCCCCCCCCEEEEEEECCCCEEEECCCCCCCEE
YLCFPNNPTGATATKEQLQAWVDYAKTNGSIIFFDAAYEAFITDESLPHSIYELEGAKDC
EEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCEEEEECCCCCCCHHHCCCCCHHH
AIEFRSFSKNAGFTGTRCAFTVVPKNLTVTASNGQAVQLWSLWNRRQSTKFNGVSYIVQR
HHHHHHCCCCCCCCCCEEEEEEECCCEEEEECCCCEEEEEHHHCCCCCCCCCHHHHHHHH
GAEAVYSEAGQAQIKTLIDFYLENAAIIRRELQAVGFDVYGGVNAPYVWVKTPAGLSSWD
CHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCEEEEECCCCCCHHH
FFDKLLINCNVVGTPGSGFGAAGEGYFRISAFNSRENVLEAMKRITTAFQ
HHHHHHEEEEEEECCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVRINENYLKLKAGYLFPEIARRVNGFLAENPNAPIIKLGIGDVTEPLPAACREAMAKAI
CEEECCCEEEEEECCCCHHHHHHHCCCEECCCCCCEEEECCCCCCCHHHHHHHHHHHHHH
DDMGDRANFKGYGPEQGYAWLREKIAAHDFQARGCDIDASEIFVSDGAKCDTGNILDIFG
HHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHEEEECCCCCCCCCEEEEEC
KDNTIAVTDPVYPVYVDTNVMAGHTGEADESGKYGGLTYIPITADNDFVAQIPTEKVDLI
CCCEEEEECCEEEEEEECCEEECCCCCCCCCCCCCCEEEEEEECCCCEEEECCCCCCCEE
YLCFPNNPTGATATKEQLQAWVDYAKTNGSIIFFDAAYEAFITDESLPHSIYELEGAKDC
EEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCEEEEECCCCCCCHHHCCCCCHHH
AIEFRSFSKNAGFTGTRCAFTVVPKNLTVTASNGQAVQLWSLWNRRQSTKFNGVSYIVQR
HHHHHHCCCCCCCCCCEEEEEEECCCEEEEECCCCEEEEEHHHCCCCCCCCCHHHHHHHH
GAEAVYSEAGQAQIKTLIDFYLENAAIIRRELQAVGFDVYGGVNAPYVWVKTPAGLSSWD
CHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCEEEEECCCCCCHHH
FFDKLLINCNVVGTPGSGFGAAGEGYFRISAFNSRENVLEAMKRITTAFQ
HHHHHHEEEEEEECCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA