Click here to switch to the map view.

The map label for this gene is queA [H]

Identifier: 170077817

GI number: 170077817

Start: 1243345

End: 1244421

Strand: Direct

Name: queA [H]

Synonym: SYNPCC7002_A1200

Alternate gene names: 170077817

Gene position: 1243345-1244421 (Clockwise)

Preceding gene: 170077815

Following gene: 170077818

Centisome position: 41.33

GC content: 51.72

Gene sequence:

>1077_bases
ATGAACCCAGACCAAAGCCTCTCAAGTTATGACTACGACCTGCCGCCGGAACGCATCGCCCAAACCCCTGTCACTCCCCG
TGATCGTTCCCGTCTGTTAGTGCTTGATTCTGTCGATAGCATCCAGCATCAGCATTTTTACCACCTGGTTGATTGGCTAC
AGCCCAATGACTTGTTGGTGATGAACAATACGAAAGTGATCCCGGCACGGCTCCATGGCCGTAAGACAACGGGCGCTCCG
GTAGAAGTCCTCCTCTTGGAAGAACGTTCAGCAGATACTTGGCTGGCTTTAGTGAAACCGGGGAAACGTTTTACCCTAGG
GTCAGAAATTTTATTCACCGCGCCCCATGATTTGAGCCAAACCCTGAAAGCAACGGTGGTTGATCGAGACCCAGAGACAG
GGGGGCGCTTACTTGAATTTCAGTTGCGGCCAAACCAAACCCTTTGGTCTGTGTTAGACGATTTTGGGGAGATCCCTTTC
CCTCCCTATGTGACGGACTCTGAGGCGAAACCCGACCAGTATCAAACGATCTATGCAGAGACTCCTGGGGCTGTGGCGGC
ACCGACGGCGGGGCTACATTTTACGCCAGAAGTGTTTGAGGCGTTAGAACAAAAGGGTGTAGAAAAAACTTTTGTGACCC
TCCATGTGGGGGTTGGCACATTCCGCCCGGTGGAAGTAGAAGATATCACCGCCCATGATATGCACTATGAGTGGATTGAC
GTGCCGGAGGAAACAGTGAAAAAAATCCGGGAAACGAAAGCAAAGGGCGGTCGGGTCATTGCGGTCGGGACAACGGTTGT
GCGATCGCTAGAGGGAATGGCCGCCGCTTCTCCTGGGGAATTACAGTCTTTCCAGGGACAAACCAATTTATTTATCTATC
CGGGTTACGAATGGCAGGTGGTGGATGGGCTGATCACGAATTTCCATTTACCAAAATCGAGCTTGCTGATGCTAGTTAGT
GCGTTGATCGGGCGCGAAAGATTGCTCGACGTTTACCAGGCGGCGATCGCCCAGGAATATCGTTTCTATTCCTTTGGGGA
TGCGATGCTCATTTTGCCTGAGGCGAAAGTCTTTTAG

Upstream 100 bases:

>100_bases
ATTGCACTTGTGTCGGTATAGTTGGAATAAAAAAATTTTGCTGTGCCGTCCTCAAAGTTGTGTTCATTATATCGGAGATT
TTTATTCGCTTCAGTGAGCT

Downstream 100 bases:

>100_bases
GGACATTAGGATTGAATCGAAAGTTTCCGCTAAGTGGCGTTATTTACAGTTTGTAGGGTATCGGTAGGAAAATTTTATGA
GCGATTTTGCCCAGCAGCTC

Product: S-adenosylmethionine:tRNA ribosyltransferase-isomerase

Products: NA

Alternate protein names: Queuosine biosynthesis protein queA [H]

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MNPDQSLSSYDYDLPPERIAQTPVTPRDRSRLLVLDSVDSIQHQHFYHLVDWLQPNDLLVMNNTKVIPARLHGRKTTGAP
VEVLLLEERSADTWLALVKPGKRFTLGSEILFTAPHDLSQTLKATVVDRDPETGGRLLEFQLRPNQTLWSVLDDFGEIPF
PPYVTDSEAKPDQYQTIYAETPGAVAAPTAGLHFTPEVFEALEQKGVEKTFVTLHVGVGTFRPVEVEDITAHDMHYEWID
VPEETVKKIRETKAKGGRVIAVGTTVVRSLEGMAAASPGELQSFQGQTNLFIYPGYEWQVVDGLITNFHLPKSSLLMLVS
ALIGRERLLDVYQAAIAQEYRFYSFGDAMLILPEAKVF

Sequences:

>Translated_358_residues
MNPDQSLSSYDYDLPPERIAQTPVTPRDRSRLLVLDSVDSIQHQHFYHLVDWLQPNDLLVMNNTKVIPARLHGRKTTGAP
VEVLLLEERSADTWLALVKPGKRFTLGSEILFTAPHDLSQTLKATVVDRDPETGGRLLEFQLRPNQTLWSVLDDFGEIPF
PPYVTDSEAKPDQYQTIYAETPGAVAAPTAGLHFTPEVFEALEQKGVEKTFVTLHVGVGTFRPVEVEDITAHDMHYEWID
VPEETVKKIRETKAKGGRVIAVGTTVVRSLEGMAAASPGELQSFQGQTNLFIYPGYEWQVVDGLITNFHLPKSSLLMLVS
ALIGRERLLDVYQAAIAQEYRFYSFGDAMLILPEAKVF
>Mature_358_residues
MNPDQSLSSYDYDLPPERIAQTPVTPRDRSRLLVLDSVDSIQHQHFYHLVDWLQPNDLLVMNNTKVIPARLHGRKTTGAP
VEVLLLEERSADTWLALVKPGKRFTLGSEILFTAPHDLSQTLKATVVDRDPETGGRLLEFQLRPNQTLWSVLDDFGEIPF
PPYVTDSEAKPDQYQTIYAETPGAVAAPTAGLHFTPEVFEALEQKGVEKTFVTLHVGVGTFRPVEVEDITAHDMHYEWID
VPEETVKKIRETKAKGGRVIAVGTTVVRSLEGMAAASPGELQSFQGQTNLFIYPGYEWQVVDGLITNFHLPKSSLLMLVS
ALIGRERLLDVYQAAIAQEYRFYSFGDAMLILPEAKVF

Specific function: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) [H]

COG id: COG0809

COG function: function code J; S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queA family [H]

Homologues:

Organism=Escherichia coli, GI1786606, Length=349, Percent_Identity=44.9856733524355, Blast_Score=302, Evalue=2e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003699 [H]

Pfam domain/function: PF02547 Queuosine_synth [H]

EC number: 5.-.-.- [C]

Molecular weight: Translated: 40117; Mature: 40117

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPDQSLSSYDYDLPPERIAQTPVTPRDRSRLLVLDSVDSIQHQHFYHLVDWLQPNDLLV
CCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHCCCCCEEE
MNNTKVIPARLHGRKTTGAPVEVLLLEERSADTWLALVKPGKRFTLGSEILFTAPHDLSQ
ECCCEEEEEEECCCCCCCCCEEEEEEECCCCCEEEEEECCCCEEEECCEEEEECCCHHHH
TLKATVVDRDPETGGRLLEFQLRPNQTLWSVLDDFGEIPFPPYVTDSEAKPDQYQTIYAE
HHEEEEECCCCCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEC
TPGAVAAPTAGLHFTPEVFEALEQKGVEKTFVTLHVGVGTFRPVEVEDITAHDMHYEWID
CCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEEECCCCCCCCEECCCEECCCEEEEEC
VPEETVKKIRETKAKGGRVIAVGTTVVRSLEGMAAASPGELQSFQGQTNLFIYPGYEWQV
CCHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHCCCCCCHHHHCCCCCCEEEECCCCEEE
VDGLITNFHLPKSSLLMLVSALIGRERLLDVYQAAIAQEYRFYSFGDAMLILPEAKVF
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCEEEEECCCCCC
>Mature Secondary Structure
MNPDQSLSSYDYDLPPERIAQTPVTPRDRSRLLVLDSVDSIQHQHFYHLVDWLQPNDLLV
CCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHCCCCCEEE
MNNTKVIPARLHGRKTTGAPVEVLLLEERSADTWLALVKPGKRFTLGSEILFTAPHDLSQ
ECCCEEEEEEECCCCCCCCCEEEEEEECCCCCEEEEEECCCCEEEECCEEEEECCCHHHH
TLKATVVDRDPETGGRLLEFQLRPNQTLWSVLDDFGEIPFPPYVTDSEAKPDQYQTIYAE
HHEEEEECCCCCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEC
TPGAVAAPTAGLHFTPEVFEALEQKGVEKTFVTLHVGVGTFRPVEVEDITAHDMHYEWID
CCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEEECCCCCCCCEECCCEECCCEEEEEC
VPEETVKKIRETKAKGGRVIAVGTTVVRSLEGMAAASPGELQSFQGQTNLFIYPGYEWQV
CCHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHCCCCCCHHHHCCCCCCEEEECCCCEEE
VDGLITNFHLPKSSLLMLVSALIGRERLLDVYQAAIAQEYRFYSFGDAMLILPEAKVF
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Isomerases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA