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The map label for this gene is trxA [H]

Identifier: 170077813

GI number: 170077813

Start: 1240431

End: 1240766

Strand: Reverse

Name: trxA [H]

Synonym: SYNPCC7002_A1196

Alternate gene names: 170077813

Gene position: 1240766-1240431 (Counterclockwise)

Preceding gene: 170077814

Following gene: 170077812

Centisome position: 41.25

GC content: 47.02

Gene sequence:

>336_bases
ATGGTTCTATCAATCACCGAAGCGGATTTTACCCAGACTGTTTTAGAAGCCAATCAACCTGTTTTGGTGAACTTTTGGGC
ACCCTGGTGTGGTTTGTGTCATTTGCTCCATCCCTTTTTGGTGAAGTTGCAAAAGGAATGGGAAGGACAATTTCTTTTGG
TCGATGTTAATGCCGACGATAACCTAAAGCTCGCCAATACCTATCGCCTCAAAACCCTCCCGACTTTAATTTTGTTCAAC
GATGGCACGATCGTCGAGCGCATCGATAAGTTCCAAAACCGCGATCGCCTTAATGCCCAGCTCGAACAACTCCTCCAGGG
CGTGGTGATCCCCTAA

Upstream 100 bases:

>100_bases
TGCCCTGGTAACGGAAAAAAAGATGATCCCCAGGACCGATACAGGTAAGATAAGAGACCACAGATAATATTGAGTATGTG
AGCGAAAAGAACAGGCAATT

Downstream 100 bases:

>100_bases
ATTTTTTATGACTGCCCCCCTCATCGTCATCTGTGGTGCCACCGCGACGGGTAAATCCGGTTTGGCCCTCAAACTTGCCG
AAAAACTGGACGCGGTAATT

Product: thioredoxin

Products: NA

Alternate protein names: Trx-1; Thioredoxin-M [H]

Number of amino acids: Translated: 111; Mature: 111

Protein sequence:

>111_residues
MVLSITEADFTQTVLEANQPVLVNFWAPWCGLCHLLHPFLVKLQKEWEGQFLLVDVNADDNLKLANTYRLKTLPTLILFN
DGTIVERIDKFQNRDRLNAQLEQLLQGVVIP

Sequences:

>Translated_111_residues
MVLSITEADFTQTVLEANQPVLVNFWAPWCGLCHLLHPFLVKLQKEWEGQFLLVDVNADDNLKLANTYRLKTLPTLILFN
DGTIVERIDKFQNRDRLNAQLEQLLQGVVIP
>Mature_111_residues
MVLSITEADFTQTVLEANQPVLVNFWAPWCGLCHLLHPFLVKLQKEWEGQFLLVDVNADDNLKLANTYRLKTLPTLILFN
DGTIVERIDKFQNRDRLNAQLEQLLQGVVIP

Specific function: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI21361403, Length=97, Percent_Identity=32.9896907216495, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI87082331, Length=104, Percent_Identity=34.6153846153846, Blast_Score=75, Evalue=7e-16,
Organism=Escherichia coli, GI1788936, Length=73, Percent_Identity=31.5068493150685, Blast_Score=64, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI212646193, Length=97, Percent_Identity=31.9587628865979, Blast_Score=65, Evalue=6e-12,
Organism=Drosophila melanogaster, GI28573567, Length=100, Percent_Identity=33, Blast_Score=69, Evalue=7e-13,

Paralogues:

None

Copy number: 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: NA

Molecular weight: Translated: 12774; Mature: 12774

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLSITEADFTQTVLEANQPVLVNFWAPWCGLCHLLHPFLVKLQKEWEGQFLLVDVNADD
CEEEECCCHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCC
NLKLANTYRLKTLPTLILFNDGTIVERIDKFQNRDRLNAQLEQLLQGVVIP
CEEEEEEEEECCCCEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MVLSITEADFTQTVLEANQPVLVNFWAPWCGLCHLLHPFLVKLQKEWEGQFLLVDVNADD
CEEEECCCHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCC
NLKLANTYRLKTLPTLILFNDGTIVERIDKFQNRDRLNAQLEQLLQGVVIP
CEEEEEEEEECCCCEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Reduction reactions; participates in dithiol-disulfide exchange reactions [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3096973; 3926769 [H]