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The map label for this gene is dxs

Identifier: 170077789

GI number: 170077789

Start: 1203793

End: 1205709

Strand: Reverse

Name: dxs

Synonym: SYNPCC7002_A1172

Alternate gene names: 170077789

Gene position: 1205709-1203793 (Counterclockwise)

Preceding gene: 170077790

Following gene: 170077788

Centisome position: 40.08

GC content: 53.57

Gene sequence:

>1917_bases
ATGCACCTGAGTGAAATTACCCATCCGAACCAACTCCACGGCTTGACCGTCCGTCAGTTGGAAGAGATTGCCCGGCAAAT
TCGCGAAAAACACCTCCAGACGATTGCCGCAAGTGGTGGCCACCTCGGCCCTGGTTTAGGGGTGGTTGAACTAACCCTCG
CCCTCTACCAAACCCTTGATCTCGATCGCGACAAGGTGGTGTGGGATGTCGGTCATCAGGCTTATCCCCATAAATTGATT
ACCGGACGCTACAACGAATTCCACACCCTCCGGCAAAAGGATGGGGTAGCTGGCTACCTTAAGCGCAGTGAAAATGTGTT
TGATCATTTTGGTGCTGGCCATGCCTCGACCAGTATTTCCGCAGCGCTAGGGATGGCATTGGCACGGGATGCCAAGGGAG
AAGAGTTTAAATGTGTGGCAGTCATTGGTGATGGTGCCTTGACCGGCGGCATGGCCCTCGAAGCCATCAACCATGCGGGT
CATTTACCCGATACGAATTTAATGGTGGTTCTCAATGACAATGAAATGTCTATTTCCCCGAATGTGGGAGCCATCTCGCG
ATACCTCAATAAAGTTCGCCTCAGTGATCCCGTTCAGTTCTTGACCGATAACCTCGAAGAACAGGTTAAGCACCTCCCGT
TCCTTGGGGACTCCCTCACCCCAGAGATGGAACGGCTTAAGGACAGCATGAAACGCTTGGCTGTCTCAAAAGTTGGCGCC
GTCATCGAAGAATTAGGCTTTAAATATTTTGGCCCCGTGGATGGCCACAACCTCGAAGAGCTGATCCGCACCTTTAAACA
GGCCCATAAAGCCAAAGGCCCGACCCTCGTCCACGTCGCCACAGTTAAAGGCAAAGGTTATGCGATCGCCGAAAAAGATC
AAGTAGGCTACCATGCCCAGAAACCCTTTGACTTGGCCACAGGCAAGGCTTTCCCCTCGAAGAAACCAACCCCACCGAGC
TATTCCAAGGTCTTTGCCCATGCCCTGACCACCCTCGCAGAAAACAACCCCAAAATTGTCGGGATTACAGCGGCGATGGC
CACTGGCACCGGGTTAGATAAGCTCCAACAGAGATTACCAAAACAGTACATCGACGTTGGTATCGCCGAACAACATGCCG
TTACCCTAGCAGCGGGCCTCGCCTGTGAAGGAATGCGGCCAGTGGTGGCGATTTATTCGACCTTCCTGCAGCGGGCCTAC
GACCAAATCATCCATGATGTTTGTATTCAAAAATTACCAGTCTTTTTCTGCCTTGACCGGGCGGGTATCGTCGGTGCCGA
CGGGCCGACCCACCAGGGGATGTATGACATTGCCTATCTCCGCCTGATTCCCAATATTGTGTTGATGGCACCCAAGGATG
AAGCTGAACTGCAACGGATGCTCGTCACGGGGATTGAATACACGGACGGGGCGATCGCCATGCGTTATCCCAGGGGGAGT
GGCATTGGCGCACCGTTAATGGAAGACGGCTGGGAACCCCTGCCCATCGGTAAAGGAGAAATCCTGCGCAATGGTGATGA
CATTCTCCTGATCGGCTATGGTGCCATGGTGCACTCGACCCTCCAGGTGGCCGAAATTCTCAGTGAACACGGCATTAGCG
CCACGGTGATCAACGCCCGTTTTGTGAAACCCCTGGATTCTGAACTCATTGCGCCCCTCGCCAAGCAAATTGGTAAAGTG
GCCACCTTTGAAGAGGGTTGCTTAATGGGGGGTTTTGGGTCTGCGGTCTGTGAAGCGCTCCAGGATCATGATGTGCTTGT
TCCCGTAAAACGCTTTGGCATTGGGGATGTGCTTGTGGATCATGCAACTCCAGCGGAATCAAAAGCGGCCCACGGGTTGA
CCCCAGCCCAGATGGCCGAATCCATTCGGGCGGCATTTTTCCAGAAAGACGCCGCCAAGACAACCACCACCGTTTAA

Upstream 100 bases:

>100_bases
ATGGGATCATCCGGACTAACCGGGATCTTCTGATTAAAATTGTTAGACCTGATATCCTGAGAACTAGACCCCTTTATAAG
ATCGCTCTCTAGAAACACCC

Downstream 100 bases:

>100_bases
GCAAAATTGACTGTGCTTTGACTTTGATCCCCAGTGCTCCCTCGCTGCCCTGGGGATTTTTTGATGGTGGAACCGTCACA
GAAAATTGCGATCGCCAAAC

Product: 1-deoxy-D-xylulose-5-phosphate synthase

Products: NA

Alternate protein names: 1-deoxyxylulose-5-phosphate synthase; DXP synthase; DXPS

Number of amino acids: Translated: 638; Mature: 638

Protein sequence:

>638_residues
MHLSEITHPNQLHGLTVRQLEEIARQIREKHLQTIAASGGHLGPGLGVVELTLALYQTLDLDRDKVVWDVGHQAYPHKLI
TGRYNEFHTLRQKDGVAGYLKRSENVFDHFGAGHASTSISAALGMALARDAKGEEFKCVAVIGDGALTGGMALEAINHAG
HLPDTNLMVVLNDNEMSISPNVGAISRYLNKVRLSDPVQFLTDNLEEQVKHLPFLGDSLTPEMERLKDSMKRLAVSKVGA
VIEELGFKYFGPVDGHNLEELIRTFKQAHKAKGPTLVHVATVKGKGYAIAEKDQVGYHAQKPFDLATGKAFPSKKPTPPS
YSKVFAHALTTLAENNPKIVGITAAMATGTGLDKLQQRLPKQYIDVGIAEQHAVTLAAGLACEGMRPVVAIYSTFLQRAY
DQIIHDVCIQKLPVFFCLDRAGIVGADGPTHQGMYDIAYLRLIPNIVLMAPKDEAELQRMLVTGIEYTDGAIAMRYPRGS
GIGAPLMEDGWEPLPIGKGEILRNGDDILLIGYGAMVHSTLQVAEILSEHGISATVINARFVKPLDSELIAPLAKQIGKV
ATFEEGCLMGGFGSAVCEALQDHDVLVPVKRFGIGDVLVDHATPAESKAAHGLTPAQMAESIRAAFFQKDAAKTTTTV

Sequences:

>Translated_638_residues
MHLSEITHPNQLHGLTVRQLEEIARQIREKHLQTIAASGGHLGPGLGVVELTLALYQTLDLDRDKVVWDVGHQAYPHKLI
TGRYNEFHTLRQKDGVAGYLKRSENVFDHFGAGHASTSISAALGMALARDAKGEEFKCVAVIGDGALTGGMALEAINHAG
HLPDTNLMVVLNDNEMSISPNVGAISRYLNKVRLSDPVQFLTDNLEEQVKHLPFLGDSLTPEMERLKDSMKRLAVSKVGA
VIEELGFKYFGPVDGHNLEELIRTFKQAHKAKGPTLVHVATVKGKGYAIAEKDQVGYHAQKPFDLATGKAFPSKKPTPPS
YSKVFAHALTTLAENNPKIVGITAAMATGTGLDKLQQRLPKQYIDVGIAEQHAVTLAAGLACEGMRPVVAIYSTFLQRAY
DQIIHDVCIQKLPVFFCLDRAGIVGADGPTHQGMYDIAYLRLIPNIVLMAPKDEAELQRMLVTGIEYTDGAIAMRYPRGS
GIGAPLMEDGWEPLPIGKGEILRNGDDILLIGYGAMVHSTLQVAEILSEHGISATVINARFVKPLDSELIAPLAKQIGKV
ATFEEGCLMGGFGSAVCEALQDHDVLVPVKRFGIGDVLVDHATPAESKAAHGLTPAQMAESIRAAFFQKDAAKTTTTV
>Mature_638_residues
MHLSEITHPNQLHGLTVRQLEEIARQIREKHLQTIAASGGHLGPGLGVVELTLALYQTLDLDRDKVVWDVGHQAYPHKLI
TGRYNEFHTLRQKDGVAGYLKRSENVFDHFGAGHASTSISAALGMALARDAKGEEFKCVAVIGDGALTGGMALEAINHAG
HLPDTNLMVVLNDNEMSISPNVGAISRYLNKVRLSDPVQFLTDNLEEQVKHLPFLGDSLTPEMERLKDSMKRLAVSKVGA
VIEELGFKYFGPVDGHNLEELIRTFKQAHKAKGPTLVHVATVKGKGYAIAEKDQVGYHAQKPFDLATGKAFPSKKPTPPS
YSKVFAHALTTLAENNPKIVGITAAMATGTGLDKLQQRLPKQYIDVGIAEQHAVTLAAGLACEGMRPVVAIYSTFLQRAY
DQIIHDVCIQKLPVFFCLDRAGIVGADGPTHQGMYDIAYLRLIPNIVLMAPKDEAELQRMLVTGIEYTDGAIAMRYPRGS
GIGAPLMEDGWEPLPIGKGEILRNGDDILLIGYGAMVHSTLQVAEILSEHGISATVINARFVKPLDSELIAPLAKQIGKV
ATFEEGCLMGGFGSAVCEALQDHDVLVPVKRFGIGDVLVDHATPAESKAAHGLTPAQMAESIRAAFFQKDAAKTTTTV

Specific function: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)

COG id: COG1154

COG function: function code HI; Deoxyxylulose-5-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family. DXPS subfamily

Homologues:

Organism=Homo sapiens, GI205277463, Length=621, Percent_Identity=23.5104669887279, Blast_Score=125, Evalue=2e-28,
Organism=Homo sapiens, GI4507521, Length=621, Percent_Identity=23.5104669887279, Blast_Score=125, Evalue=2e-28,
Organism=Homo sapiens, GI133778974, Length=632, Percent_Identity=24.0506329113924, Blast_Score=116, Evalue=6e-26,
Organism=Homo sapiens, GI225637459, Length=390, Percent_Identity=27.4358974358974, Blast_Score=104, Evalue=3e-22,
Organism=Homo sapiens, GI225637461, Length=390, Percent_Identity=27.4358974358974, Blast_Score=104, Evalue=3e-22,
Organism=Homo sapiens, GI225637463, Length=390, Percent_Identity=27.4358974358974, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI156564403, Length=266, Percent_Identity=23.3082706766917, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI4557353, Length=242, Percent_Identity=24.3801652892562, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI34101272, Length=242, Percent_Identity=24.3801652892562, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI291084858, Length=258, Percent_Identity=22.4806201550388, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI1786622, Length=623, Percent_Identity=44.9438202247191, Blast_Score=523, Evalue=1e-149,
Organism=Caenorhabditis elegans, GI17539652, Length=401, Percent_Identity=30.9226932668329, Blast_Score=149, Evalue=6e-36,
Organism=Caenorhabditis elegans, GI17538422, Length=238, Percent_Identity=26.0504201680672, Blast_Score=72, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6319698, Length=275, Percent_Identity=26.1818181818182, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI45551847, Length=654, Percent_Identity=26.9113149847095, Blast_Score=166, Evalue=4e-41,
Organism=Drosophila melanogaster, GI45550715, Length=654, Percent_Identity=26.9113149847095, Blast_Score=166, Evalue=4e-41,
Organism=Drosophila melanogaster, GI24645119, Length=610, Percent_Identity=27.3770491803279, Blast_Score=159, Evalue=4e-39,
Organism=Drosophila melanogaster, GI24666278, Length=657, Percent_Identity=25.7229832572298, Blast_Score=152, Evalue=9e-37,
Organism=Drosophila melanogaster, GI21358145, Length=345, Percent_Identity=24.9275362318841, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24650940, Length=345, Percent_Identity=24.9275362318841, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI160714832, Length=260, Percent_Identity=26.1538461538462, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI160714828, Length=260, Percent_Identity=26.1538461538462, Blast_Score=69, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DXS_SYNP2 (B1XKC5)

Other databases:

- EMBL:   CP000951
- RefSeq:   YP_001734427.1
- GeneID:   6056268
- GenomeReviews:   CP000951_GR
- KEGG:   syp:SYNPCC7002_A1172
- HOGENOM:   HBG571647
- OMA:   QRFPDRY
- ProtClustDB:   PRK05444
- HAMAP:   MF_00315
- InterPro:   IPR005477
- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474
- Gene3D:   G3DSA:3.40.50.920
- SMART:   SM00861
- TIGRFAMs:   TIGR00204

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N; SSF52922 Transketo_C_like

EC number: =2.2.1.7

Molecular weight: Translated: 68976; Mature: 68976

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: PS00801 TRANSKETOLASE_1; PS00802 TRANSKETOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHLSEITHPNQLHGLTVRQLEEIARQIREKHLQTIAASGGHLGPGLGVVELTLALYQTLD
CCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHC
LDRDKVVWDVGHQAYPHKLITGRYNEFHTLRQKDGVAGYLKRSENVFDHFGAGHASTSIS
CCCCCEEEECCCCCCCCHHHCCCCHHHHHHHHCCCCHHHHHHCCHHHHHCCCCCCHHHHH
AALGMALARDAKGEEFKCVAVIGDGALTGGMALEAINHAGHLPDTNLMVVLNDNEMSISP
HHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCEEEEECCCCEEECC
NVGAISRYLNKVRLSDPVQFLTDNLEEQVKHLPFLGDSLTPEMERLKDSMKRLAVSKVGA
CHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
VIEELGFKYFGPVDGHNLEELIRTFKQAHKAKGPTLVHVATVKGKGYAIAEKDQVGYHAQ
HHHHCCCEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEECCCCCCCCCC
KPFDLATGKAFPSKKPTPPSYSKVFAHALTTLAENNPKIVGITAAMATGTGLDKLQQRLP
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEHHHCCCCHHHHHHHCC
KQYIDVGIAEQHAVTLAAGLACEGMRPVVAIYSTFLQRAYDQIIHDVCIQKLPVFFCLDR
HHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECC
AGIVGADGPTHQGMYDIAYLRLIPNIVLMAPKDEAELQRMLVTGIEYTDGAIAMRYPRGS
CCEECCCCCCCCCHHHHHHHHHHCCEEEECCCCHHHHHHHHHHCCCCCCCEEEEECCCCC
GIGAPLMEDGWEPLPIGKGEILRNGDDILLIGYGAMVHSTLQVAEILSEHGISATVINAR
CCCCCHHHCCCCCCCCCCCCEEECCCCEEEEECHHHHHHHHHHHHHHHHCCCEEEEECHH
FVKPLDSELIAPLAKQIGKVATFEEGCLMGGFGSAVCEALQDHDVLVPVKRFGIGDVLVD
HCCCCHHHHHHHHHHHHHHHHCCCCCCEECCHHHHHHHHHHCCCEEEEHHHCCCCHHEEC
HATPAESKAAHGLTPAQMAESIRAAFFQKDAAKTTTTV
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MHLSEITHPNQLHGLTVRQLEEIARQIREKHLQTIAASGGHLGPGLGVVELTLALYQTLD
CCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHC
LDRDKVVWDVGHQAYPHKLITGRYNEFHTLRQKDGVAGYLKRSENVFDHFGAGHASTSIS
CCCCCEEEECCCCCCCCHHHCCCCHHHHHHHHCCCCHHHHHHCCHHHHHCCCCCCHHHHH
AALGMALARDAKGEEFKCVAVIGDGALTGGMALEAINHAGHLPDTNLMVVLNDNEMSISP
HHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCEEEEECCCCEEECC
NVGAISRYLNKVRLSDPVQFLTDNLEEQVKHLPFLGDSLTPEMERLKDSMKRLAVSKVGA
CHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
VIEELGFKYFGPVDGHNLEELIRTFKQAHKAKGPTLVHVATVKGKGYAIAEKDQVGYHAQ
HHHHCCCEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEECCCCCCCCCC
KPFDLATGKAFPSKKPTPPSYSKVFAHALTTLAENNPKIVGITAAMATGTGLDKLQQRLP
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEEHHHCCCCHHHHHHHCC
KQYIDVGIAEQHAVTLAAGLACEGMRPVVAIYSTFLQRAYDQIIHDVCIQKLPVFFCLDR
HHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECC
AGIVGADGPTHQGMYDIAYLRLIPNIVLMAPKDEAELQRMLVTGIEYTDGAIAMRYPRGS
CCEECCCCCCCCCHHHHHHHHHHCCEEEECCCCHHHHHHHHHHCCCCCCCEEEEECCCCC
GIGAPLMEDGWEPLPIGKGEILRNGDDILLIGYGAMVHSTLQVAEILSEHGISATVINAR
CCCCCHHHCCCCCCCCCCCCEEECCCCEEEEECHHHHHHHHHHHHHHHHCCCEEEEECHH
FVKPLDSELIAPLAKQIGKVATFEEGCLMGGFGSAVCEALQDHDVLVPVKRFGIGDVLVD
HCCCCHHHHHHHHHHHHHHHHCCCCCCEECCHHHHHHHHHHCCCEEEEHHHCCCCHHEEC
HATPAESKAAHGLTPAQMAESIRAAFFQKDAAKTTTTV
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA