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The map label for this gene is sppA [H]

Identifier: 170077749

GI number: 170077749

Start: 1163563

End: 1165347

Strand: Reverse

Name: sppA [H]

Synonym: SYNPCC7002_A1131

Alternate gene names: 170077749

Gene position: 1165347-1163563 (Counterclockwise)

Preceding gene: 170077750

Following gene: 170077746

Centisome position: 38.74

GC content: 52.61

Gene sequence:

>1785_bases
ATGAAAGATTTTTTTAAACAGGTTTTTAGCAGTTGCCTCGGTACCCTGATTGCCCTCAGCCTTCTATCGACCCTCTCTCT
GTCAGCGTTTATTGCCCTGATTGCCCTCTTCTCTGCCCAGGAAGGCGGTGGCAGGCCCAAGGAAAACAGTATTTTGATCT
TCAATATGGGCACGATCATCCAAGACCGAGATCCCTCTAGTTCCATTGGGAATGTCATTGCCGGGGATTTTCCCGAAACC
CTCAGTCTGCGGGATGTCACTGAAAGTATCCGCGCTGCCGCCGAGGATGACAAAATTACGGGACTCTTCCTCGATGGTCG
GCAAAATAGCTTGAACGGTTATGCCACGCTGCGAGAAGTGCGCCAAGCTCTCCAGGACTTTAAAGCCGCCGGGAAGAAAA
TCTATGCCTACGATGTGGAAATGACGGAGCGGGAATATTACCTGAGTTCCTTGGCCGATGAAATTTGGCTCAATCCCCTG
GGGGTTGTGGAAATGAACGGTTTGGGTAGTGAGCAGCTTTTCTTTAAGGGAGCCCTGGATCAATATGGGATCGGGGTGCA
GGTGGTGCGGGTCGGTGATTATAAAAGTGCTGTAGAACCCTTTACTCAAGAGGAATTCAGTCCTGAAAATCGCCAACAAA
CCGAGGCTCTGCTCAGTGATCTCTGGACAGATTTTAAAGATACGGTGGCTGGCGATCGCCCCTTTGCCGCAACCTTGCCC
CAGAGCCTGGCCGACACCCAGGGGATTCTTTTGCCAGAGGTGGCCCAACAGGAGCAATTGGTGACGCGCCTGGCCTATTT
TGATGAAATTCTGGCGGAGCTTAAGACCTTTACGGGGACAGAACTTGACAAAGATTTACCCCAGATGGATCTGGCCGATT
ACAGTCTGGAACAGGATTTAGCCCAGATCGGAGTCACCTCAGAAAATACCGTGGCGGTGGTCTATGCCGAGGGTAATATC
GTCGGTGGGGAAGGGACGCCGGACACCATTGGCGGGGATTCCCTCTCGCGACAACTGCGGGAGTTGCGCCAGGATCCTGA
GGTCAAAGTCGTTGTGCTGCGTATCAATAGTCCTGGGGGTAGTGCGATCGCCTCAGAAATTATCCTGCGGGAACTAAAAC
TGATCCGCGAGGCAGACAAACCCGTGATTGTTTCCATGGGGGATCTGGCGGCTTCTGGGGGCTATTGGATTGCCACCGAA
AGCGATCGCATTTTTGCCCAGCCCAATACCATTACTGGCTCGATTGGGGTGTTTGGCATTTTGCCCAATATCCAAACCAT
TGGGAATAATAATGGCCTCACCTGGGATAGCGTCCAAACGGGAGAACTGGCGAATTTAGGCACGGCGTCTCGCCCGAAAA
CCGAAGCAGAAATGGCGATTTTTCAAAATTTTGTCAATGATATTTACGGCAAATTTTTAGACCGGGTCAGTGCGGCGCGG
GGTCTTACGGAAGCTGAGGTGCGCCAAATTGCCCAGGGACGGGTCTGGTCTGGGGAAGATGCCCAGGCGATTCGGCTCGT
GGATGAGTTGGGGGGGCTATCGGCGGCGATCGCCTATGCCGTGGACACCGCAGAATTAGGGGAAGATTTCACTGTTCAAG
AATATCCCCGACCCCAAACTTGGGAAGAAGAAATTTTTAGTAATCTATTTGGGGCTCAGATCGAAGCGAGCGATCCCCTC
TCCCAAGAATGGCTCCGGCTCCAGGCCAGTATCAAACTGTGGCGATCGCTCAATGATCCCAAGCAGGTCTATGCCCTCAT
GCCCTGGCAACCCCAGATCGATTAG

Upstream 100 bases:

>100_bases
TTTTGTACGGGTAATGCTAATTTTCAGCAACTGCAACGGGCGAATTGCCTGCACAAGTTCTAAGGTAAAAACTAAGACCT
CTTTCCCGAATGCCTCAACC

Downstream 100 bases:

>100_bases
GTCGTATATTCGGCGTTAATGCGCACATAGTCATAGCTGAGGTCACAGCCCCAGGCCGTACCTTTACCAGAACCATTGCC
CACACAAACAGCAATCAACA

Product: signal peptide peptidase SppA, 67K type

Products: NA

Alternate protein names: Endopeptidase IV; Protease IV homolog; Signal peptide peptidase [H]

Number of amino acids: Translated: 594; Mature: 594

Protein sequence:

>594_residues
MKDFFKQVFSSCLGTLIALSLLSTLSLSAFIALIALFSAQEGGGRPKENSILIFNMGTIIQDRDPSSSIGNVIAGDFPET
LSLRDVTESIRAAAEDDKITGLFLDGRQNSLNGYATLREVRQALQDFKAAGKKIYAYDVEMTEREYYLSSLADEIWLNPL
GVVEMNGLGSEQLFFKGALDQYGIGVQVVRVGDYKSAVEPFTQEEFSPENRQQTEALLSDLWTDFKDTVAGDRPFAATLP
QSLADTQGILLPEVAQQEQLVTRLAYFDEILAELKTFTGTELDKDLPQMDLADYSLEQDLAQIGVTSENTVAVVYAEGNI
VGGEGTPDTIGGDSLSRQLRELRQDPEVKVVVLRINSPGGSAIASEIILRELKLIREADKPVIVSMGDLAASGGYWIATE
SDRIFAQPNTITGSIGVFGILPNIQTIGNNNGLTWDSVQTGELANLGTASRPKTEAEMAIFQNFVNDIYGKFLDRVSAAR
GLTEAEVRQIAQGRVWSGEDAQAIRLVDELGGLSAAIAYAVDTAELGEDFTVQEYPRPQTWEEEIFSNLFGAQIEASDPL
SQEWLRLQASIKLWRSLNDPKQVYALMPWQPQID

Sequences:

>Translated_594_residues
MKDFFKQVFSSCLGTLIALSLLSTLSLSAFIALIALFSAQEGGGRPKENSILIFNMGTIIQDRDPSSSIGNVIAGDFPET
LSLRDVTESIRAAAEDDKITGLFLDGRQNSLNGYATLREVRQALQDFKAAGKKIYAYDVEMTEREYYLSSLADEIWLNPL
GVVEMNGLGSEQLFFKGALDQYGIGVQVVRVGDYKSAVEPFTQEEFSPENRQQTEALLSDLWTDFKDTVAGDRPFAATLP
QSLADTQGILLPEVAQQEQLVTRLAYFDEILAELKTFTGTELDKDLPQMDLADYSLEQDLAQIGVTSENTVAVVYAEGNI
VGGEGTPDTIGGDSLSRQLRELRQDPEVKVVVLRINSPGGSAIASEIILRELKLIREADKPVIVSMGDLAASGGYWIATE
SDRIFAQPNTITGSIGVFGILPNIQTIGNNNGLTWDSVQTGELANLGTASRPKTEAEMAIFQNFVNDIYGKFLDRVSAAR
GLTEAEVRQIAQGRVWSGEDAQAIRLVDELGGLSAAIAYAVDTAELGEDFTVQEYPRPQTWEEEIFSNLFGAQIEASDPL
SQEWLRLQASIKLWRSLNDPKQVYALMPWQPQID
>Mature_594_residues
MKDFFKQVFSSCLGTLIALSLLSTLSLSAFIALIALFSAQEGGGRPKENSILIFNMGTIIQDRDPSSSIGNVIAGDFPET
LSLRDVTESIRAAAEDDKITGLFLDGRQNSLNGYATLREVRQALQDFKAAGKKIYAYDVEMTEREYYLSSLADEIWLNPL
GVVEMNGLGSEQLFFKGALDQYGIGVQVVRVGDYKSAVEPFTQEEFSPENRQQTEALLSDLWTDFKDTVAGDRPFAATLP
QSLADTQGILLPEVAQQEQLVTRLAYFDEILAELKTFTGTELDKDLPQMDLADYSLEQDLAQIGVTSENTVAVVYAEGNI
VGGEGTPDTIGGDSLSRQLRELRQDPEVKVVVLRINSPGGSAIASEIILRELKLIREADKPVIVSMGDLAASGGYWIATE
SDRIFAQPNTITGSIGVFGILPNIQTIGNNNGLTWDSVQTGELANLGTASRPKTEAEMAIFQNFVNDIYGKFLDRVSAAR
GLTEAEVRQIAQGRVWSGEDAQAIRLVDELGGLSAAIAYAVDTAELGEDFTVQEYPRPQTWEEEIFSNLFGAQIEASDPL
SQEWLRLQASIKLWRSLNDPKQVYALMPWQPQID

Specific function: Digestion of the cleaved signal peptides. This activity is necessary to maintain proper secretion of mature proteins across the membrane [H]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1788064, Length=601, Percent_Identity=33.7770382695507, Blast_Score=310, Evalue=2e-85,
Organism=Escherichia coli, GI1787527, Length=214, Percent_Identity=27.5700934579439, Blast_Score=79, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004634
- InterPro:   IPR004635
- InterPro:   IPR002142 [H]

Pfam domain/function: PF01343 Peptidase_S49 [H]

EC number: 3.4.21.-

Molecular weight: Translated: 65132; Mature: 65132

Theoretical pI: Translated: 4.08; Mature: 4.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDFFKQVFSSCLGTLIALSLLSTLSLSAFIALIALFSAQEGGGRPKENSILIFNMGTII
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCEE
QDRDPSSSIGNVIAGDFPETLSLRDVTESIRAAAEDDKITGLFLDGRQNSLNGYATLREV
ECCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHH
RQALQDFKAAGKKIYAYDVEMTEREYYLSSLADEIWLNPLGVVEMNGLGSEQLFFKGALD
HHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHEECCHH
QYGIGVQVVRVGDYKSAVEPFTQEEFSPENRQQTEALLSDLWTDFKDTVAGDRPFAATLP
HCCCCEEEEEECCCHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
QSLADTQGILLPEVAQQEQLVTRLAYFDEILAELKTFTGTELDKDLPQMDLADYSLEQDL
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHH
AQIGVTSENTVAVVYAEGNIVGGEGTPDTIGGDSLSRQLRELRQDPEVKVVVLRINSPGG
HHHCCCCCCEEEEEEECCEEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCC
SAIASEIILRELKLIREADKPVIVSMGDLAASGGYWIATESDRIFAQPNTITGSIGVFGI
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEECCCEEEECCCCCCCCCEEEEE
LPNIQTIGNNNGLTWDSVQTGELANLGTASRPKTEAEMAIFQNFVNDIYGKFLDRVSAAR
CCCCEECCCCCCCEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
GLTEAEVRQIAQGRVWSGEDAQAIRLVDELGGLSAAIAYAVDTAELGEDFTVQEYPRPQT
CCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCC
WEEEIFSNLFGAQIEASDPLSQEWLRLQASIKLWRSLNDPKQVYALMPWQPQID
HHHHHHHHHHCCEECCCCCHHHHHHHHHHHHHHHHCCCCHHHEEEECCCCCCCC
>Mature Secondary Structure
MKDFFKQVFSSCLGTLIALSLLSTLSLSAFIALIALFSAQEGGGRPKENSILIFNMGTII
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCEE
QDRDPSSSIGNVIAGDFPETLSLRDVTESIRAAAEDDKITGLFLDGRQNSLNGYATLREV
ECCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHH
RQALQDFKAAGKKIYAYDVEMTEREYYLSSLADEIWLNPLGVVEMNGLGSEQLFFKGALD
HHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHEECCHH
QYGIGVQVVRVGDYKSAVEPFTQEEFSPENRQQTEALLSDLWTDFKDTVAGDRPFAATLP
HCCCCEEEEEECCCHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
QSLADTQGILLPEVAQQEQLVTRLAYFDEILAELKTFTGTELDKDLPQMDLADYSLEQDL
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHH
AQIGVTSENTVAVVYAEGNIVGGEGTPDTIGGDSLSRQLRELRQDPEVKVVVLRINSPGG
HHHCCCCCCEEEEEEECCEEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCC
SAIASEIILRELKLIREADKPVIVSMGDLAASGGYWIATESDRIFAQPNTITGSIGVFGI
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEECCCEEEECCCCCCCCCEEEEE
LPNIQTIGNNNGLTWDSVQTGELANLGTASRPKTEAEMAIFQNFVNDIYGKFLDRVSAAR
CCCCEECCCCCCCEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
GLTEAEVRQIAQGRVWSGEDAQAIRLVDELGGLSAAIAYAVDTAELGEDFTVQEYPRPQT
CCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCC
WEEEIFSNLFGAQIEASDPLSQEWLRLQASIKLWRSLNDPKQVYALMPWQPQID
HHHHHHHHHHCCEECCCCCHHHHHHHHHHHHHHHHCCCCHHHEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]