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The map label for this gene is crp [C]

Identifier: 170077697

GI number: 170077697

Start: 1107536

End: 1107910

Strand: Direct

Name: crp [C]

Synonym: SYNPCC7002_A1077

Alternate gene names: 170077697

Gene position: 1107536-1107910 (Clockwise)

Preceding gene: 170077696

Following gene: 170077699

Centisome position: 36.82

GC content: 51.2

Gene sequence:

>375_bases
ATGATGGCGCATTTTGACTTATTTAGACATGACCACGACACCCAAGATTTCGCGGCGGGCACTGTAATTTTTAGCGCAGG
CACCCCGGGCGATCTGCTCTACATTATCCAAACCGGGGAAGTGGAAATTCAGTTTCAAGGGCAACCCTTGAGTATCCTCG
GTGAAGGGGAAGCTTTAGGAGAAATGGCCGTCATTGAGCCGGGTTCCCCCCGCAGTGCGACGGCGATCGCCAAAACGGAT
TGTCGCCTCGTGGTGATTGACCAAAAGCGATTTACGTTTCTCATCCAGCAAAATCCCTACTTTGCCATCGAAATCATGAA
AACCTTAGCCGAGCGTTTAAGTCGCACGAACCAAAAGCTAGAGGCCCAGGGTTAG

Upstream 100 bases:

>100_bases
AATACGCAAAAAAGCGGTCTTAGCTCCACTATGATCGTGAATAGGCGGGCATTGGCTCGTTTTTAGAAATTTATTTCGAG
AGTTCAGAAGGAACTAAATC

Downstream 100 bases:

>100_bases
GGACAGTCGTTAACAAAAGTGCCTTGCGGTTGGATCTCGCTGAGAAGATTCATTGGGAAAAGACGCTTAAATTCATCCCC
TGGGAAATGGCAGATCAGGG

Product: cyclic nucleotide-binding domain-containing protein

Products: NA

Alternate protein names: Crp/Fnr Family Transcriptional Regulator; Crp Family Transcriptional Regulator; Transcriptional Regulatory Protein; Regulator Of K+ Conductance; Histidine Kinase; Transcriptional Regulator; Crp/FNR Family Transcriptional Regulator; Catabolite Gene Activator; Signal Transduction Protein

Number of amino acids: Translated: 124; Mature: 124

Protein sequence:

>124_residues
MMAHFDLFRHDHDTQDFAAGTVIFSAGTPGDLLYIIQTGEVEIQFQGQPLSILGEGEALGEMAVIEPGSPRSATAIAKTD
CRLVVIDQKRFTFLIQQNPYFAIEIMKTLAERLSRTNQKLEAQG

Sequences:

>Translated_124_residues
MMAHFDLFRHDHDTQDFAAGTVIFSAGTPGDLLYIIQTGEVEIQFQGQPLSILGEGEALGEMAVIEPGSPRSATAIAKTD
CRLVVIDQKRFTFLIQQNPYFAIEIMKTLAERLSRTNQKLEAQG
>Mature_124_residues
MMAHFDLFRHDHDTQDFAAGTVIFSAGTPGDLLYIIQTGEVEIQFQGQPLSILGEGEALGEMAVIEPGSPRSATAIAKTD
CRLVVIDQKRFTFLIQQNPYFAIEIMKTLAERLSRTNQKLEAQG

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789756, Length=118, Percent_Identity=30.5084745762712, Blast_Score=59, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 13728; Mature: 13728

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS00889 CNMP_BINDING_2 ; PS50042 CNMP_BINDING_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMAHFDLFRHDHDTQDFAAGTVIFSAGTPGDLLYIIQTGEVEIQFQGQPLSILGEGEALG
CCCCCCHHCCCCCCCCCEEEEEEEECCCCCCEEEEEECCCEEEEECCCCEEEEECCCCCC
EMAVIEPGSPRSATAIAKTDCRLVVIDQKRFTFLIQQNPYFAIEIMKTLAERLSRTNQKL
CEEEECCCCCCCCEEEEECCCEEEEECCCEEEEEEECCCEEEHHHHHHHHHHHHHCCCEE
EAQG
ECCC
>Mature Secondary Structure
MMAHFDLFRHDHDTQDFAAGTVIFSAGTPGDLLYIIQTGEVEIQFQGQPLSILGEGEALG
CCCCCCHHCCCCCCCCCEEEEEEEECCCCCCEEEEEECCCEEEEECCCCEEEEECCCCCC
EMAVIEPGSPRSATAIAKTDCRLVVIDQKRFTFLIQQNPYFAIEIMKTLAERLSRTNQKL
CEEEECCCCCCCCEEEEECCCEEEEECCCEEEEEEECCCEEEHHHHHHHHHHHHHCCCEE
EAQG
ECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA