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The map label for this gene is ndk

Identifier: 170077436

GI number: 170077436

Start: 840639

End: 841088

Strand: Direct

Name: ndk

Synonym: SYNPCC7002_A0814

Alternate gene names: 170077436

Gene position: 840639-841088 (Clockwise)

Preceding gene: 170077435

Following gene: 170077439

Centisome position: 27.95

GC content: 54.22

Gene sequence:

>450_bases
GTGGAACGCACATTTGTAATGGTTAAACCGGACGGTGTTCAGCGCGGTTTGGTCGGCGATGTTATCCGTCGTTTTGAAGC
AAAAGGCTTTAAGCTCGTCGGTCTAAAATTGGTTTCTGTTTCCCGCGAATTAGCAGAGCAGCACTACGGCGTTCACAGAG
AAAGACCGTTCTTCGGTAGCCTCGTAGAATTCATTATTTCTGTCCCCGTCGTCGCCATGGTTTGGGAAGGTAAAGGGGCG
ATCGCCGCCGCCCGGAAAATCATCGGTGCCACCAACCCCCTCGAAGCAGAACCCGGCACAATCCGGGGTGACTTCGGTGT
GGACATTGGCCGTAACCTGATCCACGGTTCCGATGGCCCCGACACCGCTGCCAGTGAAATTGCCCTCTGGTTCTCCGAAT
CTGAATTGGCCAACTGGGAACCCGCCACCAAAGCTTGGCTCTACGAATAA

Upstream 100 bases:

>100_bases
GAAAAATAAAGGCGATCGCCCACTCCATTTTAGGCGCAACGAAGGGTAAAACTTATGTTACGCTGACCTGTGGTTTTGTA
TATGTCCAAAGGAGAATTCT

Downstream 100 bases:

>100_bases
ATCCAATCTGTTTGGTTTCCAAGCAAATTTCGGCAATTTAATTTTTTCAAGACCTCGTTCAACCCCAACGAGGTTTTTTC
GTGGCTATTCCTCTTCATCC

Product: nucleoside diphosphate kinase

Products: NA

Alternate protein names: NDK; NDP kinase; Nucleoside-2-P kinase

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MERTFVMVKPDGVQRGLVGDVIRRFEAKGFKLVGLKLVSVSRELAEQHYGVHRERPFFGSLVEFIISVPVVAMVWEGKGA
IAAARKIIGATNPLEAEPGTIRGDFGVDIGRNLIHGSDGPDTAASEIALWFSESELANWEPATKAWLYE

Sequences:

>Translated_149_residues
MERTFVMVKPDGVQRGLVGDVIRRFEAKGFKLVGLKLVSVSRELAEQHYGVHRERPFFGSLVEFIISVPVVAMVWEGKGA
IAAARKIIGATNPLEAEPGTIRGDFGVDIGRNLIHGSDGPDTAASEIALWFSESELANWEPATKAWLYE
>Mature_149_residues
MERTFVMVKPDGVQRGLVGDVIRRFEAKGFKLVGLKLVSVSRELAEQHYGVHRERPFFGSLVEFIISVPVVAMVWEGKGA
IAAARKIIGATNPLEAEPGTIRGDFGVDIGRNLIHGSDGPDTAASEIALWFSESELANWEPATKAWLYE

Specific function: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate

COG id: COG0105

COG function: function code F; Nucleoside diphosphate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NDK family

Homologues:

Organism=Homo sapiens, GI37693993, Length=148, Percent_Identity=60.8108108108108, Blast_Score=192, Evalue=1e-49,
Organism=Homo sapiens, GI38045913, Length=149, Percent_Identity=53.0201342281879, Blast_Score=181, Evalue=3e-46,
Organism=Homo sapiens, GI4557797, Length=149, Percent_Identity=53.0201342281879, Blast_Score=180, Evalue=3e-46,
Organism=Homo sapiens, GI66392203, Length=149, Percent_Identity=52.3489932885906, Blast_Score=177, Evalue=4e-45,
Organism=Homo sapiens, GI66392227, Length=149, Percent_Identity=52.3489932885906, Blast_Score=176, Evalue=5e-45,
Organism=Homo sapiens, GI66392205, Length=149, Percent_Identity=52.3489932885906, Blast_Score=176, Evalue=5e-45,
Organism=Homo sapiens, GI4505409, Length=149, Percent_Identity=52.3489932885906, Blast_Score=176, Evalue=5e-45,
Organism=Homo sapiens, GI66392192, Length=149, Percent_Identity=52.3489932885906, Blast_Score=176, Evalue=5e-45,
Organism=Homo sapiens, GI4826862, Length=138, Percent_Identity=55.0724637681159, Blast_Score=158, Evalue=2e-39,
Organism=Homo sapiens, GI37574614, Length=136, Percent_Identity=33.8235294117647, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI7019465, Length=136, Percent_Identity=33.8235294117647, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI5031951, Length=143, Percent_Identity=31.4685314685315, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1788866, Length=137, Percent_Identity=43.7956204379562, Blast_Score=127, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17506807, Length=149, Percent_Identity=51.6778523489933, Blast_Score=169, Evalue=4e-43,
Organism=Saccharomyces cerevisiae, GI6322783, Length=148, Percent_Identity=56.7567567567568, Blast_Score=186, Evalue=1e-48,
Organism=Drosophila melanogaster, GI45549037, Length=148, Percent_Identity=60.1351351351351, Blast_Score=193, Evalue=3e-50,
Organism=Drosophila melanogaster, GI18860097, Length=140, Percent_Identity=30, Blast_Score=81, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NDK_SYNP2 (B1XIE7)

Other databases:

- EMBL:   CP000951
- RefSeq:   YP_001734074.1
- ProteinModelPortal:   B1XIE7
- SMR:   B1XIE7
- GeneID:   6057455
- GenomeReviews:   CP000951_GR
- KEGG:   syp:SYNPCC7002_A0814
- HOGENOM:   HBG445152
- OMA:   ERPFFGA
- GO:   GO:0005737
- HAMAP:   MF_00451
- InterPro:   IPR001564
- InterPro:   IPR023005
- Gene3D:   G3DSA:3.30.70.141
- PANTHER:   PTHR11349
- PRINTS:   PR01243
- SMART:   SM00562

Pfam domain/function: PF00334 NDK; SSF54919 NDK

EC number: =2.7.4.6

Molecular weight: Translated: 16352; Mature: 16352

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS00469 NDP_KINASES

Important sites: ACT_SITE 115-115 BINDING 9-9 BINDING 57-57 BINDING 85-85 BINDING 91-91 BINDING 102-102 BINDING 112-112

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERTFVMVKPDGVQRGLVGDVIRRFEAKGFKLVGLKLVSVSRELAEQHYGVHRERPFFGS
CCCCEEEECCCCCCCCHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHCCCCCCCCHHHH
LVEFIISVPVVAMVWEGKGAIAAARKIIGATNPLEAEPGTIRGDFGVDIGRNLIHGSDGP
HHHHHHHCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCHHCCCCCCC
DTAASEIALWFSESELANWEPATKAWLYE
CCCHHHEEEEECCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MERTFVMVKPDGVQRGLVGDVIRRFEAKGFKLVGLKLVSVSRELAEQHYGVHRERPFFGS
CCCCEEEECCCCCCCCHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHCCCCCCCCHHHH
LVEFIISVPVVAMVWEGKGAIAAARKIIGATNPLEAEPGTIRGDFGVDIGRNLIHGSDGP
HHHHHHHCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCHHCCCCCCC
DTAASEIALWFSESELANWEPATKAWLYE
CCCHHHEEEEECCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA