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The map label for this gene is pqqL [C]

Identifier: 170077147

GI number: 170077147

Start: 551649

End: 552935

Strand: Direct

Name: pqqL [C]

Synonym: SYNPCC7002_A0522

Alternate gene names: 170077147

Gene position: 551649-552935 (Clockwise)

Preceding gene: 170077144

Following gene: 170077148

Centisome position: 18.34

GC content: 50.19

Gene sequence:

>1287_bases
ATGACTTCCATCCTAGTGCCCAGCCCACGCCTCAACCAACCAACGATTAAGACCCTGGCCAATGGGTTGACAATCATTGC
CGAACAGGTGCCGGTTGATGCCGTGAGCCTCAATGTGTGGCTCAATGTGGGGTCTGCGGTGGAAGCCAACAGCATTAATG
GGATGGCCCATTTCCTGGAGCACATGGTCTTTAAGGGAACGCCCCAAATCGGCAATGGCGAATTTGAACAGCGCATCGAA
GCTAAAGGAGCCGTCACCAACGCCGCCACTAGCCAAGAATACACCCACTATTACATTACCTGTGCGCCCCAGGATTTTGC
GGAACTTGCGCCCCTGCAACTGGACGTGGTGCTAAATCCTAGCATTCCCGATGCTGCCTTTGAGCGGGAACGCCAGGTGG
TGCTCGAAGAAATTCGTCGTTCCGAGGATAATCCCCGCCGTCGTACCTATTTCCGCGCCATTGAAACGGGATTTGAGCGG
TTGCCCTACCGTCGTCCGGTGCTCGGCCCTAGTGAGGTGATTGAAAATCTTCAAGCCCAACAAATGCGGGATTTCCACGG
CTTTTGGTACCAACCCCAACGGATGACTGCCGCCGTTGCCGGAAATCTAGAAGGCGATCGCCTGATTGAATTAGTTGCCG
CAGCCTTCGATAAACTGTATCAATCCCAACCCACAGCAACCGTTCCCACCTTTGACGATCACTCTCCCGAAGCCCCTTTT
CAAAATATTGTGCGTCGTCATTATGAAGATGAAGGCCTACAGCAAGCTCGTTTAGTGATGATGTGGCGTGTGCCGGGGCT
AACGGATCTCGAAGAAACCTATGCCCTCGACATTTTAGCGACGGTATTAGGGCAAGGTAAAGTTTCGCGCCTCGTGCAGG
ATCTCCGGGAAAAAAGAGGTCTGGTGACTCAAATCAGCGTTAGTAACTTCACCCAAAAACAACAGGGCGTTTTCTATATT
TCTGCCCAATTACCAAGCGAAAATATTCCCGCCGTAGAAGCGGCGATTCTTGAACAAATTCAAACCATTCGTACCGCTTC
TATTTTGCCCAACGAATTAGAGCGGGTGAAAACTCAAGTAGCTAATCGCTTTATTTTGGGGAATGAACGGCCCAGCGATC
GCACCAATTTATACGGTTACTATTACTCGCTATTACGGGATCTCGAACCCGCTTTAAATTATCCGGAATTACTCCAAGCC
ATTACCCTCGAAACAATTCAAAAATCTGTACAAAAATATCTCAATCCCGAAGCTTACGGAATTGTTACCCTGACGCCACC
TGCCTAA

Upstream 100 bases:

>100_bases
CCCAAAAACCTGTCCCCAAAAACCTTCTGTAAAAACTCGATGAACAACATTGCGTTAAAGTAAAAACACGGAAAAACTTT
GAATTGCCAGCGCTTCGCCC

Downstream 100 bases:

>100_bases
ACTTTGAAAGGATGTCAGTCTCTTCTTTAAGAATATTTTGCTTGTTGAAATAAGTTGGTAGTACGGACGATATCCTGAGG
GAATAAACCCGTGGGTTAGG

Product: Zn-dependent peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MTSILVPSPRLNQPTIKTLANGLTIIAEQVPVDAVSLNVWLNVGSAVEANSINGMAHFLEHMVFKGTPQIGNGEFEQRIE
AKGAVTNAATSQEYTHYYITCAPQDFAELAPLQLDVVLNPSIPDAAFERERQVVLEEIRRSEDNPRRRTYFRAIETGFER
LPYRRPVLGPSEVIENLQAQQMRDFHGFWYQPQRMTAAVAGNLEGDRLIELVAAAFDKLYQSQPTATVPTFDDHSPEAPF
QNIVRRHYEDEGLQQARLVMMWRVPGLTDLEETYALDILATVLGQGKVSRLVQDLREKRGLVTQISVSNFTQKQQGVFYI
SAQLPSENIPAVEAAILEQIQTIRTASILPNELERVKTQVANRFILGNERPSDRTNLYGYYYSLLRDLEPALNYPELLQA
ITLETIQKSVQKYLNPEAYGIVTLTPPA

Sequences:

>Translated_428_residues
MTSILVPSPRLNQPTIKTLANGLTIIAEQVPVDAVSLNVWLNVGSAVEANSINGMAHFLEHMVFKGTPQIGNGEFEQRIE
AKGAVTNAATSQEYTHYYITCAPQDFAELAPLQLDVVLNPSIPDAAFERERQVVLEEIRRSEDNPRRRTYFRAIETGFER
LPYRRPVLGPSEVIENLQAQQMRDFHGFWYQPQRMTAAVAGNLEGDRLIELVAAAFDKLYQSQPTATVPTFDDHSPEAPF
QNIVRRHYEDEGLQQARLVMMWRVPGLTDLEETYALDILATVLGQGKVSRLVQDLREKRGLVTQISVSNFTQKQQGVFYI
SAQLPSENIPAVEAAILEQIQTIRTASILPNELERVKTQVANRFILGNERPSDRTNLYGYYYSLLRDLEPALNYPELLQA
ITLETIQKSVQKYLNPEAYGIVTLTPPA
>Mature_427_residues
TSILVPSPRLNQPTIKTLANGLTIIAEQVPVDAVSLNVWLNVGSAVEANSINGMAHFLEHMVFKGTPQIGNGEFEQRIEA
KGAVTNAATSQEYTHYYITCAPQDFAELAPLQLDVVLNPSIPDAAFERERQVVLEEIRRSEDNPRRRTYFRAIETGFERL
PYRRPVLGPSEVIENLQAQQMRDFHGFWYQPQRMTAAVAGNLEGDRLIELVAAAFDKLYQSQPTATVPTFDDHSPEAPFQ
NIVRRHYEDEGLQQARLVMMWRVPGLTDLEETYALDILATVLGQGKVSRLVQDLREKRGLVTQISVSNFTQKQQGVFYIS
AQLPSENIPAVEAAILEQIQTIRTASILPNELERVKTQVANRFILGNERPSDRTNLYGYYYSLLRDLEPALNYPELLQAI
TLETIQKSVQKYLNPEAYGIVTLTPPA

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI46593007, Length=270, Percent_Identity=29.6296296296296, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI94538354, Length=208, Percent_Identity=32.2115384615385, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI155969707, Length=337, Percent_Identity=24.6290801186944, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI24308013, Length=202, Percent_Identity=25.7425742574257, Blast_Score=69, Evalue=7e-12,
Organism=Escherichia coli, GI1787770, Length=217, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71999683, Length=228, Percent_Identity=29.8245614035088, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17553678, Length=328, Percent_Identity=27.7439024390244, Blast_Score=106, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6323192, Length=221, Percent_Identity=28.9592760180996, Blast_Score=102, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6321813, Length=381, Percent_Identity=20.997375328084, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21357875, Length=214, Percent_Identity=30.8411214953271, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24646943, Length=214, Percent_Identity=30.8411214953271, Blast_Score=124, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 48227; Mature: 48096

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS00143 INSULINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSILVPSPRLNQPTIKTLANGLTIIAEQVPVDAVSLNVWLNVGSAVEANSINGMAHFLE
CCCEECCCCCCCCCHHHHHHCCHHEEHHHCCCCEEEEEEEEECCCCCCCCCCHHHHHHHH
HMVFKGTPQIGNGEFEQRIEAKGAVTNAATSQEYTHYYITCAPQDFAELAPLQLDVVLNP
HHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCEEEEEEECCHHHHHCCCEEEEEEECC
SIPDAAFERERQVVLEEIRRSEDNPRRRTYFRAIETGFERLPYRRPVLGPSEVIENLQAQ
CCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
QMRDFHGFWYQPQRMTAAVAGNLEGDRLIELVAAAFDKLYQSQPTATVPTFDDHSPEAPF
HHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHH
QNIVRRHYEDEGLQQARLVMMWRVPGLTDLEETYALDILATVLGQGKVSRLVQDLREKRG
HHHHHHHHHHCCHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC
LVTQISVSNFTQKQQGVFYISAQLPSENIPAVEAAILEQIQTIRTASILPNELERVKTQV
CEEEEEHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
ANRFILGNERPSDRTNLYGYYYSLLRDLEPALNYPELLQAITLETIQKSVQKYLNPEAYG
HHEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCEE
IVTLTPPA
EEEECCCC
>Mature Secondary Structure 
TSILVPSPRLNQPTIKTLANGLTIIAEQVPVDAVSLNVWLNVGSAVEANSINGMAHFLE
CCEECCCCCCCCCHHHHHHCCHHEEHHHCCCCEEEEEEEEECCCCCCCCCCHHHHHHHH
HMVFKGTPQIGNGEFEQRIEAKGAVTNAATSQEYTHYYITCAPQDFAELAPLQLDVVLNP
HHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCEEEEEEECCHHHHHCCCEEEEEEECC
SIPDAAFERERQVVLEEIRRSEDNPRRRTYFRAIETGFERLPYRRPVLGPSEVIENLQAQ
CCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
QMRDFHGFWYQPQRMTAAVAGNLEGDRLIELVAAAFDKLYQSQPTATVPTFDDHSPEAPF
HHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHH
QNIVRRHYEDEGLQQARLVMMWRVPGLTDLEETYALDILATVLGQGKVSRLVQDLREKRG
HHHHHHHHHHCCHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC
LVTQISVSNFTQKQQGVFYISAQLPSENIPAVEAAILEQIQTIRTASILPNELERVKTQV
CEEEEEHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
ANRFILGNERPSDRTNLYGYYYSLLRDLEPALNYPELLQAITLETIQKSVQKYLNPEAYG
HHEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCEE
IVTLTPPA
EEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]