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The map label for this gene is aspS

Identifier: 170077050

GI number: 170077050

Start: 441692

End: 443482

Strand: Direct

Name: aspS

Synonym: SYNPCC7002_A0422

Alternate gene names: 170077050

Gene position: 441692-443482 (Clockwise)

Preceding gene: 170077035

Following gene: 170077059

Centisome position: 14.68

GC content: 52.71

Gene sequence:

>1791_bases
ATGCGTACTCATTACTGCGGGGATTTGCGCTCCGAGCACATTGACCAGACCGTAACCCTGTATGGCTGGGTCGATCGCCG
TCGGGATCATGGTGGCGTAATTTTTATTGATCTGCGCGATCGCACGGGCATTGTCCAGATTGTCAGTGACCCCCAGCGAA
CCCCAGATTCCTACAATGATGCCGATGCTAGCCGTAGTGAGTATGTTGTAAAAATTGTTGGGAAAGTCAGTGCCCGCCAA
GAAGGGGCGAAGAATCCCAAATTGCCCACTGGCGAAGTGGAGATCTACGCTGACACCATCGAGATCCTAAATGGCGTCCA
TAAACAGCTACCGATCCTCGTTTCCAGTAGTGCCGACGGCGATCAAGTCAAAGAAGACCTCCGGCTAAAATATCGCTACC
TCGACCTGCGCCGGGAAACCATGGCGAAAAACCTCCAACTGCGCCACACCGTCGTCAAATCCATGCGCCGCTTCCTGGAA
GACGATGAAAACTTCATGGAGGTGGAAACGCCAATTCTGACCCGGTCTACCCCCGAAGGGGCGCGGGATTATCTGGTGCC
GTCCCGGGTGAACCCAGGCGATTGGTATGCCCTGCCCCAGTCGCCTCAGCTTTTTAAGCAATTGCTGATGGTGGCCGGTT
GCGATCGCTACTATCAAATTGCCCGTTGCTTCCGGGACGAAGACCTCCGGGCCGACCGTCAACCGGAATTTACCCAGTTG
GATATGGAAATGAGCTTCATGTCCTTCGACGAAATCATTGACCTCAACGAACGCTTAATTTGTCGTATTTTCCAGGATGC
CCAAGGCATTGAACTAGAGCGTCCCTTCCCGCGCATCACCTACGCCGAGTCCATGGAGAAATATGGCTGCGATCGCCCCG
ATACGCGCTTTGGCCTGGAGCTGGTCAACGTCTCTGATATCGTTGCGGACATGGGCTTTAAAGTCTTTTCTGGCGCGGTT
AAGAGCGGTGGCCAAGTAAAAGTCCTCCCGATTCCCAACGGAAATGATGCCATTTCCAATGTACGGATCAAGCCCGGTGG
CGATCTATTTAATGCCGCCGTCGAAATGGGGGCCAAAGGGCTTGCCTTTATTCGGGTGCGGGAAGACGGGGCAATTGATA
CCATCGGCGCGATCAAGGACAACCTCAGTGACGCCCAAAAACAAGAACTTCTCAGTCGTACTGGGGCTGAAGCGGGCACG
CTCCTCCTCTTTGGGGCCGGGGCGACGGATATTGTCAATAAGTCTCTAGACCGGGTGCGACAGTTAGTCGGTGCTGAGAT
GGGCTTGATCAATGAAAATCAGCTCAATTTTGTTTGGGTTACGGATTTTCCGATGTTTGAATACAACAGCGACGAAAAAC
GCCTCGAAGCCCTACATCATCCCTTTACTGCACCGAATCCAGAAGATCTAGAAGATCTGGCAACGGCCCGTGCCCTCGCC
TACGACATCGTCTTAAATGGCATTGAAATCGGTGGTGGCAGTCTACGGATTTACCAGCGGGAAGTCCAAGAAAAAGTCTT
CCAGACCATTGGCTTATCAGAAACCGAGGCCCAAGAAAAATTTGGTTTTCTGCTCGAAGCCTTTGAATATGGCACCCCAC
CCCATGGCGGCATTGCCTACGGTTTAGATCGTTTGGTGATGCTTATGGCCCAGGAAGATTCCATTCGCGATGTAATTGCC
TTCCCGAAAACACAACAGGCAAGCTGTCTGTTGACCGATGCGCCGGCGGGAGTCGATCAAAAGCAACTGAAGGAACTTTT
TGTCGCTTCTACGGCCCCAGAAAAAGACTAG

Upstream 100 bases:

>100_bases
CTTAAGTTTGGGATGCCCAAGAGAATGTAGGCAAGACCCAGGATCTTTGGTAGGCTTAGTATCGCTTTAAAACTCTATGC
TTTAACTATATATACTAACT

Downstream 100 bases:

>100_bases
GCCATGGGCTTTCAAGACAACTGAAATTGTCATTTCAAAAAGAATAATGGGGGATGATCGTGCAATTTCTGCGATCGCCC
CTGTTTTTTTGTGCTCTACA

Product: aspartyl-tRNA synthetase

Products: NA

Alternate protein names: Aspartate--tRNA ligase; AspRS

Number of amino acids: Translated: 596; Mature: 596

Protein sequence:

>596_residues
MRTHYCGDLRSEHIDQTVTLYGWVDRRRDHGGVIFIDLRDRTGIVQIVSDPQRTPDSYNDADASRSEYVVKIVGKVSARQ
EGAKNPKLPTGEVEIYADTIEILNGVHKQLPILVSSSADGDQVKEDLRLKYRYLDLRRETMAKNLQLRHTVVKSMRRFLE
DDENFMEVETPILTRSTPEGARDYLVPSRVNPGDWYALPQSPQLFKQLLMVAGCDRYYQIARCFRDEDLRADRQPEFTQL
DMEMSFMSFDEIIDLNERLICRIFQDAQGIELERPFPRITYAESMEKYGCDRPDTRFGLELVNVSDIVADMGFKVFSGAV
KSGGQVKVLPIPNGNDAISNVRIKPGGDLFNAAVEMGAKGLAFIRVREDGAIDTIGAIKDNLSDAQKQELLSRTGAEAGT
LLLFGAGATDIVNKSLDRVRQLVGAEMGLINENQLNFVWVTDFPMFEYNSDEKRLEALHHPFTAPNPEDLEDLATARALA
YDIVLNGIEIGGGSLRIYQREVQEKVFQTIGLSETEAQEKFGFLLEAFEYGTPPHGGIAYGLDRLVMLMAQEDSIRDVIA
FPKTQQASCLLTDAPAGVDQKQLKELFVASTAPEKD

Sequences:

>Translated_596_residues
MRTHYCGDLRSEHIDQTVTLYGWVDRRRDHGGVIFIDLRDRTGIVQIVSDPQRTPDSYNDADASRSEYVVKIVGKVSARQ
EGAKNPKLPTGEVEIYADTIEILNGVHKQLPILVSSSADGDQVKEDLRLKYRYLDLRRETMAKNLQLRHTVVKSMRRFLE
DDENFMEVETPILTRSTPEGARDYLVPSRVNPGDWYALPQSPQLFKQLLMVAGCDRYYQIARCFRDEDLRADRQPEFTQL
DMEMSFMSFDEIIDLNERLICRIFQDAQGIELERPFPRITYAESMEKYGCDRPDTRFGLELVNVSDIVADMGFKVFSGAV
KSGGQVKVLPIPNGNDAISNVRIKPGGDLFNAAVEMGAKGLAFIRVREDGAIDTIGAIKDNLSDAQKQELLSRTGAEAGT
LLLFGAGATDIVNKSLDRVRQLVGAEMGLINENQLNFVWVTDFPMFEYNSDEKRLEALHHPFTAPNPEDLEDLATARALA
YDIVLNGIEIGGGSLRIYQREVQEKVFQTIGLSETEAQEKFGFLLEAFEYGTPPHGGIAYGLDRLVMLMAQEDSIRDVIA
FPKTQQASCLLTDAPAGVDQKQLKELFVASTAPEKD
>Mature_596_residues
MRTHYCGDLRSEHIDQTVTLYGWVDRRRDHGGVIFIDLRDRTGIVQIVSDPQRTPDSYNDADASRSEYVVKIVGKVSARQ
EGAKNPKLPTGEVEIYADTIEILNGVHKQLPILVSSSADGDQVKEDLRLKYRYLDLRRETMAKNLQLRHTVVKSMRRFLE
DDENFMEVETPILTRSTPEGARDYLVPSRVNPGDWYALPQSPQLFKQLLMVAGCDRYYQIARCFRDEDLRADRQPEFTQL
DMEMSFMSFDEIIDLNERLICRIFQDAQGIELERPFPRITYAESMEKYGCDRPDTRFGLELVNVSDIVADMGFKVFSGAV
KSGGQVKVLPIPNGNDAISNVRIKPGGDLFNAAVEMGAKGLAFIRVREDGAIDTIGAIKDNLSDAQKQELLSRTGAEAGT
LLLFGAGATDIVNKSLDRVRQLVGAEMGLINENQLNFVWVTDFPMFEYNSDEKRLEALHHPFTAPNPEDLEDLATARALA
YDIVLNGIEIGGGSLRIYQREVQEKVFQTIGLSETEAQEKFGFLLEAFEYGTPPHGGIAYGLDRLVMLMAQEDSIRDVIA
FPKTQQASCLLTDAPAGVDQKQLKELFVASTAPEKD

Specific function: Unknown

COG id: COG0173

COG function: function code J; Aspartyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI40789249, Length=610, Percent_Identity=39.672131147541, Blast_Score=407, Evalue=1e-113,
Organism=Homo sapiens, GI5031815, Length=307, Percent_Identity=26.0586319218241, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI194272210, Length=309, Percent_Identity=25.8899676375405, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI45439306, Length=274, Percent_Identity=25.1824817518248, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1788173, Length=596, Percent_Identity=47.3154362416107, Blast_Score=534, Evalue=1e-153,
Organism=Escherichia coli, GI1789256, Length=300, Percent_Identity=27.6666666666667, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1790571, Length=300, Percent_Identity=27, Blast_Score=95, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI32566633, Length=601, Percent_Identity=34.7753743760399, Blast_Score=331, Evalue=5e-91,
Organism=Caenorhabditis elegans, GI71994340, Length=316, Percent_Identity=24.0506329113924, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17535925, Length=316, Percent_Identity=24.0506329113924, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17535927, Length=316, Percent_Identity=24.0506329113924, Blast_Score=88, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71984122, Length=297, Percent_Identity=27.9461279461279, Blast_Score=82, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6325153, Length=641, Percent_Identity=31.8252730109204, Blast_Score=259, Evalue=1e-69,
Organism=Saccharomyces cerevisiae, GI6320242, Length=299, Percent_Identity=27.0903010033445, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6321807, Length=259, Percent_Identity=28.1853281853282, Blast_Score=84, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6323011, Length=307, Percent_Identity=29.6416938110749, Blast_Score=83, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6324256, Length=195, Percent_Identity=27.6923076923077, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24584738, Length=604, Percent_Identity=38.2450331125828, Blast_Score=382, Evalue=1e-106,
Organism=Drosophila melanogaster, GI24640849, Length=293, Percent_Identity=23.8907849829352, Blast_Score=85, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24640851, Length=293, Percent_Identity=23.8907849829352, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI19921528, Length=288, Percent_Identity=28.4722222222222, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI17136276, Length=266, Percent_Identity=27.0676691729323, Blast_Score=73, Evalue=5e-13,

Paralogues:

None

Copy number: 1320 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYD_SYNP2 (B1XNY9)

Other databases:

- EMBL:   CP000951
- RefSeq:   YP_001733688.1
- ProteinModelPortal:   B1XNY9
- SMR:   B1XNY9
- GeneID:   6056297
- GenomeReviews:   CP000951_GR
- KEGG:   syp:SYNPCC7002_A0422
- HOGENOM:   HBG396032
- OMA:   AFPKTQQ
- ProtClustDB:   PRK00476
- GO:   GO:0005737
- HAMAP:   MF_00044_B
- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR020564
- InterPro:   IPR004524
- InterPro:   IPR018153
- InterPro:   IPR002312
- InterPro:   IPR004115
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365
- Gene3D:   G3DSA:3.30.1360.30
- Gene3D:   G3DSA:2.40.50.140
- PANTHER:   PTHR22594
- PANTHER:   PTHR22594:SF5
- PRINTS:   PR01042
- TIGRFAMs:   TIGR00459

Pfam domain/function: PF02938 GAD; PF00152 tRNA-synt_2; PF01336 tRNA_anti; SSF50249 Nucleic_acid_OB

EC number: =6.1.1.12

Molecular weight: Translated: 66912; Mature: 66912

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTHYCGDLRSEHIDQTVTLYGWVDRRRDHGGVIFIDLRDRTGIVQIVSDPQRTPDSYND
CCCCCCCCHHHHHCCCEEEEEEEHHCCCCCCCEEEEEECCCCCEEEEECCCCCCCCCCCC
ADASRSEYVVKIVGKVSARQEGAKNPKLPTGEVEIYADTIEILNGVHKQLPILVSSSADG
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHCCEEEECCCCH
DQVKEDLRLKYRYLDLRRETMAKNLQLRHTVVKSMRRFLEDDENFMEVETPILTRSTPEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEECCCCCC
ARDYLVPSRVNPGDWYALPQSPQLFKQLLMVAGCDRYYQIARCFRDEDLRADRQPEFTQL
CHHCCCCCCCCCCCEEECCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCEEE
DMEMSFMSFDEIIDLNERLICRIFQDAQGIELERPFPRITYAESMEKYGCDRPDTRFGLE
CHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCEE
LVNVSDIVADMGFKVFSGAVKSGGQVKVLPIPNGNDAISNVRIKPGGDLFNAAVEMGAKG
EECHHHHHHHCCHHHHHHHHCCCCEEEEEECCCCCCCCCEEEECCCCHHHHHHHHCCCCC
LAFIRVREDGAIDTIGAIKDNLSDAQKQELLSRTGAEAGTLLLFGAGATDIVNKSLDRVR
EEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHH
QLVGAEMGLINENQLNFVWVTDFPMFEYNSDEKRLEALHHPFTAPNPEDLEDLATARALA
HHHHHHHCCCCCCCEEEEEEECCCCEECCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
YDIVLNGIEIGGGSLRIYQREVQEKVFQTIGLSETEAQEKFGFLLEAFEYGTPPHGGIAY
HHHHEECEEECCCEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHH
GLDRLVMLMAQEDSIRDVIAFPKTQQASCLLTDAPAGVDQKQLKELFVASTAPEKD
HHHHHHHHHHCCCCHHHHHCCCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRTHYCGDLRSEHIDQTVTLYGWVDRRRDHGGVIFIDLRDRTGIVQIVSDPQRTPDSYND
CCCCCCCCHHHHHCCCEEEEEEEHHCCCCCCCEEEEEECCCCCEEEEECCCCCCCCCCCC
ADASRSEYVVKIVGKVSARQEGAKNPKLPTGEVEIYADTIEILNGVHKQLPILVSSSADG
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHCCEEEECCCCH
DQVKEDLRLKYRYLDLRRETMAKNLQLRHTVVKSMRRFLEDDENFMEVETPILTRSTPEG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEECCCCCC
ARDYLVPSRVNPGDWYALPQSPQLFKQLLMVAGCDRYYQIARCFRDEDLRADRQPEFTQL
CHHCCCCCCCCCCCEEECCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCEEE
DMEMSFMSFDEIIDLNERLICRIFQDAQGIELERPFPRITYAESMEKYGCDRPDTRFGLE
CHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCEE
LVNVSDIVADMGFKVFSGAVKSGGQVKVLPIPNGNDAISNVRIKPGGDLFNAAVEMGAKG
EECHHHHHHHCCHHHHHHHHCCCCEEEEEECCCCCCCCCEEEECCCCHHHHHHHHCCCCC
LAFIRVREDGAIDTIGAIKDNLSDAQKQELLSRTGAEAGTLLLFGAGATDIVNKSLDRVR
EEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHH
QLVGAEMGLINENQLNFVWVTDFPMFEYNSDEKRLEALHHPFTAPNPEDLEDLATARALA
HHHHHHHCCCCCCCEEEEEEECCCCEECCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
YDIVLNGIEIGGGSLRIYQREVQEKVFQTIGLSETEAQEKFGFLLEAFEYGTPPHGGIAY
HHHHEECEEECCCEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHH
GLDRLVMLMAQEDSIRDVIAFPKTQQASCLLTDAPAGVDQKQLKELFVASTAPEKD
HHHHHHHHHHCCCCHHHHHCCCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA