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The map label for this gene is nrdB [H]

Identifier: 170077010

GI number: 170077010

Start: 406722

End: 407780

Strand: Direct

Name: nrdB [H]

Synonym: SYNPCC7002_A0382

Alternate gene names: 170077010

Gene position: 406722-407780 (Clockwise)

Preceding gene: 170077009

Following gene: 170077011

Centisome position: 13.52

GC content: 49.1

Gene sequence:

>1059_bases
ATGCAACAATCTCTCCTTGACCGGATGCCCACCAATCCCATCTTTAATCCCGATGGGAATGACGATATCGCCCACCGTTC
CATTTGGTTCGGGGAAACTACCAACCTGATGCAGCTGAACGACGTTCGCTACCCTTGGGCGGTGGGACTGTACCAACAGA
TGCGCGAAAACTTTTGGATTCCCCAGAAGCTGGACATTACCCAGGATGTCACCGACTACCACAACCTGACAGATTCAGAA
CGCCGCGCCTTTGACGGGATCCTCAGCTACCTCACATTCCTTGATTCTGTCCAAACCTGTAATCTTCCTCACATCAAAAG
CTCGATTACGGCCCCAGAGATTAGCCTGTGCATCGCCGAGCAGATCTCCCAGGAGGGGATGCACAACCAGTCCTATCAAT
ACATGATTGAGACGATTATCCCTAGCGATCGCCGCAGTGCCGTCTATGATTTTTGGCGTACGGATAAAGTCTTACGCGAT
CGCTGTGAGTACATTGCCAGCAACTACCAACGCTACATTGACAACCCCACCCCAGAAAATTACTTCACAACCCTCGTCGC
CGACTATTTGCTAGAAGGGCTGTATTTTTACAATGGTTTTGTGTTCTTCTATAACCTTGCCTCGCGGATGTTGATGCCCG
GTTCTGCGGATATCTTTAAGATGATTAACCGGGACGAACTCAGCCACGTGCGCCTATTCCAAAAACTGATCCCAGAGGCC
ATGGCCACCTTTGATCACTCTGTCGATCACATCTATGAAATGGTGGAACGGGCTGTACAGTACGAATGCCAATGGACAAA
CCACATTGTCGGCAACGATATCCTCGGCATTACAGAACAAAGCACCGAGATTTACACCAAGTATTTAGCGAATATTCGTC
TTCAAGCTATCGGCCTCGAACCGTTGTACAAAGGGGATCAATACAAGAAAAGCCCCTACCGTCACCTCGAACGATTCTCA
GACACAAAAAAAGAAGGCAACACCAAAGCCAACTTCTTTGAGGCCGGGGTGACCAGCTACGTGATGTCATCGGGAATTAC
GGGTTGGGATGAATTTTAA

Upstream 100 bases:

>100_bases
TCCAACTACACCCATCACTGGTGTGGTATCTCTCAGCAAACTCTTTTAAACTAAACTAAGACCTTTTAAGATTTGTATCC
TCTACGCGGCCCCAGCCACT

Downstream 100 bases:

>100_bases
ACAGACACTGGGGGCGATAATGCAGCAAAAAATCTGTAGTTTGTTGTACTGTTTTTCGTCCCTTATTCTGCCCGCAGTCG
CAATGAGCTAAAATTAGCGT

Product: ribonucleoside-diphosphate reductase, beta subunit

Products: NA

Alternate protein names: Ribonucleotide reductase small subunit [H]

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MQQSLLDRMPTNPIFNPDGNDDIAHRSIWFGETTNLMQLNDVRYPWAVGLYQQMRENFWIPQKLDITQDVTDYHNLTDSE
RRAFDGILSYLTFLDSVQTCNLPHIKSSITAPEISLCIAEQISQEGMHNQSYQYMIETIIPSDRRSAVYDFWRTDKVLRD
RCEYIASNYQRYIDNPTPENYFTTLVADYLLEGLYFYNGFVFFYNLASRMLMPGSADIFKMINRDELSHVRLFQKLIPEA
MATFDHSVDHIYEMVERAVQYECQWTNHIVGNDILGITEQSTEIYTKYLANIRLQAIGLEPLYKGDQYKKSPYRHLERFS
DTKKEGNTKANFFEAGVTSYVMSSGITGWDEF

Sequences:

>Translated_352_residues
MQQSLLDRMPTNPIFNPDGNDDIAHRSIWFGETTNLMQLNDVRYPWAVGLYQQMRENFWIPQKLDITQDVTDYHNLTDSE
RRAFDGILSYLTFLDSVQTCNLPHIKSSITAPEISLCIAEQISQEGMHNQSYQYMIETIIPSDRRSAVYDFWRTDKVLRD
RCEYIASNYQRYIDNPTPENYFTTLVADYLLEGLYFYNGFVFFYNLASRMLMPGSADIFKMINRDELSHVRLFQKLIPEA
MATFDHSVDHIYEMVERAVQYECQWTNHIVGNDILGITEQSTEIYTKYLANIRLQAIGLEPLYKGDQYKKSPYRHLERFS
DTKKEGNTKANFFEAGVTSYVMSSGITGWDEF
>Mature_352_residues
MQQSLLDRMPTNPIFNPDGNDDIAHRSIWFGETTNLMQLNDVRYPWAVGLYQQMRENFWIPQKLDITQDVTDYHNLTDSE
RRAFDGILSYLTFLDSVQTCNLPHIKSSITAPEISLCIAEQISQEGMHNQSYQYMIETIIPSDRRSAVYDFWRTDKVLRD
RCEYIASNYQRYIDNPTPENYFTTLVADYLLEGLYFYNGFVFFYNLASRMLMPGSADIFKMINRDELSHVRLFQKLIPEA
MATFDHSVDHIYEMVERAVQYECQWTNHIVGNDILGITEQSTEIYTKYLANIRLQAIGLEPLYKGDQYKKSPYRHLERFS
DTKKEGNTKANFFEAGVTSYVMSSGITGWDEF

Specific function: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides [H]

COG id: COG0208

COG function: function code F; Ribonucleotide reductase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribonucleoside diphosphate reductase small chain family [H]

Homologues:

Organism=Homo sapiens, GI42544136, Length=305, Percent_Identity=23.2786885245902, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI289177074, Length=305, Percent_Identity=23.2786885245902, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI4557845, Length=306, Percent_Identity=23.202614379085, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI260064013, Length=306, Percent_Identity=23.202614379085, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI289177076, Length=308, Percent_Identity=23.0519480519481, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1788567, Length=322, Percent_Identity=25.1552795031056, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1789031, Length=323, Percent_Identity=22.9102167182663, Blast_Score=85, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17551968, Length=293, Percent_Identity=23.8907849829352, Blast_Score=88, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI193206379, Length=298, Percent_Identity=20.8053691275168, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322434, Length=293, Percent_Identity=23.8907849829352, Blast_Score=77, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6321619, Length=303, Percent_Identity=20.7920792079208, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI18079279, Length=297, Percent_Identity=24.2424242424242, Blast_Score=93, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009078
- InterPro:   IPR012348
- InterPro:   IPR000358 [H]

Pfam domain/function: PF00268 Ribonuc_red_sm [H]

EC number: =1.17.4.1 [H]

Molecular weight: Translated: 41219; Mature: 41219

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQSLLDRMPTNPIFNPDGNDDIAHRSIWFGETTNLMQLNDVRYPWAVGLYQQMRENFWI
CCHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCEEECCCCCCHHHHHHHHHHHCCCC
PQKLDITQDVTDYHNLTDSERRAFDGILSYLTFLDSVQTCNLPHIKSSITAPEISLCIAE
CCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHH
QISQEGMHNQSYQYMIETIIPSDRRSAVYDFWRTDKVLRDRCEYIASNYQRYIDNPTPEN
HHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
YFTTLVADYLLEGLYFYNGFVFFYNLASRMLMPGSADIFKMINRDELSHVRLFQKLIPEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCHHHHHHHHHHHHHHHHH
MATFDHSVDHIYEMVERAVQYECQWTNHIVGNDILGITEQSTEIYTKYLANIRLQAIGLE
HHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCEEEEECCC
PLYKGDQYKKSPYRHLERFSDTKKEGNTKANFFEAGVTSYVMSSGITGWDEF
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MQQSLLDRMPTNPIFNPDGNDDIAHRSIWFGETTNLMQLNDVRYPWAVGLYQQMRENFWI
CCHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCEEECCCCCCHHHHHHHHHHHCCCC
PQKLDITQDVTDYHNLTDSERRAFDGILSYLTFLDSVQTCNLPHIKSSITAPEISLCIAE
CCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHH
QISQEGMHNQSYQYMIETIIPSDRRSAVYDFWRTDKVLRDRCEYIASNYQRYIDNPTPEN
HHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
YFTTLVADYLLEGLYFYNGFVFFYNLASRMLMPGSADIFKMINRDELSHVRLFQKLIPEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCHHHHHHHHHHHHHHHHH
MATFDHSVDHIYEMVERAVQYECQWTNHIVGNDILGITEQSTEIYTKYLANIRLQAIGLE
HHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCEEEEECCC
PLYKGDQYKKSPYRHLERFSDTKKEGNTKANFFEAGVTSYVMSSGITGWDEF
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]