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The map label for this gene is uppS [H]

Identifier: 170076733

GI number: 170076733

Start: 100643

End: 101380

Strand: Direct

Name: uppS [H]

Synonym: SYNPCC7002_A0099

Alternate gene names: 170076733

Gene position: 100643-101380 (Clockwise)

Preceding gene: 170076732

Following gene: 170076734

Centisome position: 3.35

GC content: 51.63

Gene sequence:

>738_bases
ATGGTTCATCCTTTGCCCGCTGACCTCGATCCCCAAAAGCTTCCCAAACACATCGCTGTCATCATGGATGGGAATGGTCG
TTGGGGCCAACAGCGTGGTTTACCTAGAATTATGGGTCATCAAAAAGGGGTAGACACAATCCGCAATATGCTCACCTACT
GCCAAGACTGGGGAATCCATGCCCTCACGGTCTATGCGTTCTCCACCGAAAACTGGCGGCGTCCCCCCACCGAGGTGGAA
TTTTTGATGACCTTGTTTGAAAAGGTGCTGCGGCGAGAAATTAAAATTTGGGCGGCCAAAGGGATTCAAATTCGCTTTGT
GGGGGATCTGACCTCCTTACCCTATTCCCTCCAGGCGGAAATTCAACGCTCCGTCATTCAAACCCAGCACAATAATGGCA
TTCAATTTACCGTTGCCACCAACTACGGCGGCCGCCAAGAATTAGTCCAGGCCTGTCGGGCGATCGCCACCAAAGTTGCT
GCCGGGGAACTGCGACCCAGCGATATCAATGAAACCTTGATCAACGATCACCTTTATACCCACGGCATCCCTGATCCCGA
TCTTTTGATCCGTACCAGCGGTGAAATGCGCCTGAGTAATTTTTTGTTGTGGCAAATGGCCTATAGCGAAATTTATGTCA
CCCCCACCCTCTGGCCCGATTTTGACAAAACCGAACTCCACCGCGCCCTCTTGGCTTTCCAACAACGGGAACGTCGCTTC
GGTAAAGCCACCGTTTAA

Upstream 100 bases:

>100_bases
CCTGGGTCGTCGGCTAAAATCTCAAGGGGAAGATTTACTCAAGTTTCTTCGGCAACTGAATCTCCCTTTCACCCACAAAG
ATTAACCTTTGACTGTAACT

Downstream 100 bases:

>100_bases
TCCCCTGAACAATGTCATAAAATCGCCATGCAGTTATCTAAGGCTGAGCTTCGGGTATTGTTTAAAAAAAATTGCGCCAA
GGAGTTGACATATACAATTT

Product: undecaprenyl diphosphate synthase

Products: NA

Alternate protein names: UPP synthase 1; Di-trans,poly-cis-decaprenylcistransferase 1; Undecaprenyl diphosphate synthase 1; UDS 1 [H]

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MVHPLPADLDPQKLPKHIAVIMDGNGRWGQQRGLPRIMGHQKGVDTIRNMLTYCQDWGIHALTVYAFSTENWRRPPTEVE
FLMTLFEKVLRREIKIWAAKGIQIRFVGDLTSLPYSLQAEIQRSVIQTQHNNGIQFTVATNYGGRQELVQACRAIATKVA
AGELRPSDINETLINDHLYTHGIPDPDLLIRTSGEMRLSNFLLWQMAYSEIYVTPTLWPDFDKTELHRALLAFQQRERRF
GKATV

Sequences:

>Translated_245_residues
MVHPLPADLDPQKLPKHIAVIMDGNGRWGQQRGLPRIMGHQKGVDTIRNMLTYCQDWGIHALTVYAFSTENWRRPPTEVE
FLMTLFEKVLRREIKIWAAKGIQIRFVGDLTSLPYSLQAEIQRSVIQTQHNNGIQFTVATNYGGRQELVQACRAIATKVA
AGELRPSDINETLINDHLYTHGIPDPDLLIRTSGEMRLSNFLLWQMAYSEIYVTPTLWPDFDKTELHRALLAFQQRERRF
GKATV
>Mature_245_residues
MVHPLPADLDPQKLPKHIAVIMDGNGRWGQQRGLPRIMGHQKGVDTIRNMLTYCQDWGIHALTVYAFSTENWRRPPTEVE
FLMTLFEKVLRREIKIWAAKGIQIRFVGDLTSLPYSLQAEIQRSVIQTQHNNGIQFTVATNYGGRQELVQACRAIATKVA
AGELRPSDINETLINDHLYTHGIPDPDLLIRTSGEMRLSNFLLWQMAYSEIYVTPTLWPDFDKTELHRALLAFQQRERRF
GKATV

Specific function: Generates undecaprenyl pyrophosphate (UPP) from isopentenyl pyrophosphate (IPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide [H]

COG id: COG0020

COG function: function code I; Undecaprenyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI45580738, Length=234, Percent_Identity=41.8803418803419, Blast_Score=179, Evalue=2e-45,
Organism=Homo sapiens, GI45580742, Length=225, Percent_Identity=42.6666666666667, Blast_Score=179, Evalue=2e-45,
Organism=Escherichia coli, GI1786371, Length=240, Percent_Identity=45.4166666666667, Blast_Score=229, Evalue=1e-61,
Organism=Caenorhabditis elegans, GI71993029, Length=227, Percent_Identity=36.5638766519824, Blast_Score=147, Evalue=5e-36,
Organism=Saccharomyces cerevisiae, GI6319474, Length=226, Percent_Identity=35.8407079646018, Blast_Score=134, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6323748, Length=227, Percent_Identity=32.15859030837, Blast_Score=103, Evalue=3e-23,
Organism=Drosophila melanogaster, GI18857969, Length=226, Percent_Identity=35.3982300884956, Blast_Score=158, Evalue=3e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001441
- InterPro:   IPR018520 [H]

Pfam domain/function: PF01255 Prenyltransf [H]

EC number: =2.5.1.31 [H]

Molecular weight: Translated: 28137; Mature: 28137

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: PS01066 UPP_SYNTHETASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVHPLPADLDPQKLPKHIAVIMDGNGRWGQQRGLPRIMGHQKGVDTIRNMLTYCQDWGIH
CCCCCCCCCCHHHCCCEEEEEECCCCCCCHHCCCHHHHCCCCCHHHHHHHHHHHHCCCCE
ALTVYAFSTENWRRPPTEVEFLMTLFEKVLRREIKIWAAKGIQIRFVGDLTSLPYSLQAE
EEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCEEEEEECCHHHCCHHHHHH
IQRSVIQTQHNNGIQFTVATNYGGRQELVQACRAIATKVAAGELRPSDINETLINDHLYT
HHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCHHC
HGIPDPDLLIRTSGEMRLSNFLLWQMAYSEIYVTPTLWPDFDKTELHRALLAFQQRERRF
CCCCCCCEEEECCCCHHHHHHHHHHHHHCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHC
GKATV
CCCCC
>Mature Secondary Structure
MVHPLPADLDPQKLPKHIAVIMDGNGRWGQQRGLPRIMGHQKGVDTIRNMLTYCQDWGIH
CCCCCCCCCCHHHCCCEEEEEECCCCCCCHHCCCHHHHCCCCCHHHHHHHHHHHHCCCCE
ALTVYAFSTENWRRPPTEVEFLMTLFEKVLRREIKIWAAKGIQIRFVGDLTSLPYSLQAE
EEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCEEEEEECCHHHCCHHHHHH
IQRSVIQTQHNNGIQFTVATNYGGRQELVQACRAIATKVAAGELRPSDINETLINDHLYT
HHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCHHC
HGIPDPDLLIRTSGEMRLSNFLLWQMAYSEIYVTPTLWPDFDKTELHRALLAFQQRERRF
CCCCCCCEEEECCCCHHHHHHHHHHHHHCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHC
GKATV
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]