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The map label for this gene is cysQ [H]

Identifier: 170025990

GI number: 170025990

Start: 4164621

End: 4165361

Strand: Reverse

Name: cysQ [H]

Synonym: YPK_3775

Alternate gene names: 170025990

Gene position: 4165361-4164621 (Counterclockwise)

Preceding gene: 170025993

Following gene: 170025988

Centisome position: 88.82

GC content: 53.44

Gene sequence:

>741_bases
ATGTTAGAGCAAATTGGCCAGTTGGCCCGTGAGGCAGGCGTGGCGATTATGGCGGTCTATCAGGGCGACAAACCCCTTGA
TATTGCGCATAAAAAGGATGATTCACCGGTGACGGCGGCTGATTTGGCGGCTCACCAGATTATCAAAGCTGGGTTGGCGC
GATTAACCCCGGATATTCCGCTACTCTCTGAAGAGGATCCACCCGCTTGGGATGTGCGCCAACACTGGCAACGCTACTGG
CTGGTTGACCCGCTGGACGGTACTAAAGAGTTCCTCAATCGTAACGGTGAATTCACCGTCAACATCGCTTTGATTGACCA
AGGTGAACCGGTACTGGGCGTCGTCTATGTACCGGTAACCGAAGTGATGTACAGCGCGGCAAACGGACAGGCTTGGAAAG
AAGAGTGTGGCAGACGTATGCAGATTCAGGTGCGTGATGCCCAGCCTCCGTTGGTCGTGGTGAGCCGCTCTCATAGCGAT
GCTGAATTGGAAGACTATTTATCACAACTGGGGGAGCATCAAACTATTTCGGTGGGCTCATCACTTAAATTCTGCTTGGT
GGCGGAAGGGAAAGCGCAACTGTACCCGCGTTTTGGGCCAACTAACGTCTGGGATACGGCGGCTGGTCATGCCGTCGCCA
TCGCTGCCGGGGCGCAAGTACACGATTGGCAGGGAAAGACACTGTCTTATACCCCACGTGAATCTTTCTTGAACCCCGGT
TTCAGAGTTTCGTTATTTTAG

Upstream 100 bases:

>100_bases
ACTCTTACTCCAAGAGCTACAGTTAACTCAAGAGCGACAATTAATTTGGTGCGCTCTGATGAGCGATATTTTACATAATG
GATAATACCAAGGGGGGATG

Downstream 100 bases:

>100_bases
CGTTATTGCTGCACAAGTTGGTGCAGTTGGTCGATGACCTGCTGCACCTCTGCTGATGTCAGTGCTCCATCTTTTACAAA
TTTGACATTTCCTTGTGGAT

Product: adenosine-3'(2'),5'-bisphosphate nucleotidase

Products: NA

Alternate protein names: 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase [H]

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MLEQIGQLAREAGVAIMAVYQGDKPLDIAHKKDDSPVTAADLAAHQIIKAGLARLTPDIPLLSEEDPPAWDVRQHWQRYW
LVDPLDGTKEFLNRNGEFTVNIALIDQGEPVLGVVYVPVTEVMYSAANGQAWKEECGRRMQIQVRDAQPPLVVVSRSHSD
AELEDYLSQLGEHQTISVGSSLKFCLVAEGKAQLYPRFGPTNVWDTAAGHAVAIAAGAQVHDWQGKTLSYTPRESFLNPG
FRVSLF

Sequences:

>Translated_246_residues
MLEQIGQLAREAGVAIMAVYQGDKPLDIAHKKDDSPVTAADLAAHQIIKAGLARLTPDIPLLSEEDPPAWDVRQHWQRYW
LVDPLDGTKEFLNRNGEFTVNIALIDQGEPVLGVVYVPVTEVMYSAANGQAWKEECGRRMQIQVRDAQPPLVVVSRSHSD
AELEDYLSQLGEHQTISVGSSLKFCLVAEGKAQLYPRFGPTNVWDTAAGHAVAIAAGAQVHDWQGKTLSYTPRESFLNPG
FRVSLF
>Mature_246_residues
MLEQIGQLAREAGVAIMAVYQGDKPLDIAHKKDDSPVTAADLAAHQIIKAGLARLTPDIPLLSEEDPPAWDVRQHWQRYW
LVDPLDGTKEFLNRNGEFTVNIALIDQGEPVLGVVYVPVTEVMYSAANGQAWKEECGRRMQIQVRDAQPPLVVVSRSHSD
AELEDYLSQLGEHQTISVGSSLKFCLVAEGKAQLYPRFGPTNVWDTAAGHAVAIAAGAQVHDWQGKTLSYTPRESFLNPG
FRVSLF

Specific function: Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) [H]

COG id: COG1218

COG function: function code P; 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Escherichia coli, GI1790659, Length=246, Percent_Identity=78.4552845528455, Blast_Score=389, Evalue=1e-110,
Organism=Escherichia coli, GI1788882, Length=234, Percent_Identity=26.9230769230769, Blast_Score=72, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71995897, Length=263, Percent_Identity=28.1368821292776, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71995905, Length=263, Percent_Identity=28.1368821292776, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641722, Length=267, Percent_Identity=26.2172284644195, Blast_Score=79, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006240
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 27114; Mature: 27114

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00629 IMP_1 ; PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEQIGQLAREAGVAIMAVYQGDKPLDIAHKKDDSPVTAADLAAHQIIKAGLARLTPDIP
CHHHHHHHHHHCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
LLSEEDPPAWDVRQHWQRYWLVDPLDGTKEFLNRNGEFTVNIALIDQGEPVLGVVYVPVT
CCCCCCCCCCHHHHHHHHEEEECCCCHHHHHHCCCCCEEEEEEEEECCCCEEEEEEECHH
EVMYSAANGQAWKEECGRRMQIQVRDAQPPLVVVSRSHSDAELEDYLSQLGEHQTISVGS
HHHHHCCCCCHHHHHCCCEEEEEEECCCCCEEEEECCCCCCHHHHHHHHHCCCEEEEECC
SLKFCLVAEGKAQLYPRFGPTNVWDTAAGHAVAIAAGAQVHDWQGKTLSYTPRESFLNPG
CEEEEEEECCCCEECCCCCCCCCCCCCCCCEEEEEECCEEECCCCCEEEECCHHHHCCCC
FRVSLF
EEEEEC
>Mature Secondary Structure
MLEQIGQLAREAGVAIMAVYQGDKPLDIAHKKDDSPVTAADLAAHQIIKAGLARLTPDIP
CHHHHHHHHHHCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
LLSEEDPPAWDVRQHWQRYWLVDPLDGTKEFLNRNGEFTVNIALIDQGEPVLGVVYVPVT
CCCCCCCCCCHHHHHHHHEEEECCCCHHHHHHCCCCCEEEEEEEEECCCCEEEEEEECHH
EVMYSAANGQAWKEECGRRMQIQVRDAQPPLVVVSRSHSDAELEDYLSQLGEHQTISVGS
HHHHHCCCCCHHHHHCCCEEEEEEECCCCCEEEEECCCCCCHHHHHHHHHCCCEEEEECC
SLKFCLVAEGKAQLYPRFGPTNVWDTAAGHAVAIAAGAQVHDWQGKTLSYTPRESFLNPG
CEEEEEEECCCCEECCCCCCCCCCCCCCCCEEEEEECCEEECCCCCEEEECCHHHHCCCC
FRVSLF
EEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]