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The map label for this gene is intZ [H]

Identifier: 170025969

GI number: 170025969

Start: 4143060

End: 4144283

Strand: Reverse

Name: intZ [H]

Synonym: YPK_3754

Alternate gene names: 170025969

Gene position: 4144283-4143060 (Counterclockwise)

Preceding gene: 170025970

Following gene: 170025968

Centisome position: 88.37

GC content: 46.57

Gene sequence:

>1224_bases
ATGGCGGGAACTAACAAACTCAGCGATAAAAAATTAAAGTCTCTCCATTGTATCAATAGTGATTCTGTCAAAATGTTTGC
TGATGGTGCTGGGTTAAGCGCTAAGGTTTCCGCGCAAGGTAGCATTAGCTGGGTGTTCACTTATCGGCTTGGTGGGCGAG
AGTCTAAATTGGAGCGGTTAGTTTTTGGGCGCTATCCAGATATGACACTGAAAGCGGCAAGAGATAGGCGTGACCAATGT
CGAACATGGTTAGCTGGTGGTTGTGATCCCCGCCGTCAATTGCTGGAAGATGTTACGCAGACATTGAAGCCGGTCACTGT
AAAAGACGCACTCCTATACTGGGTCGATAATTACGCCCAAACAAATCGTAGTGACGTTGATTCTATCCGTTCTCAGTTCG
CCACTTATATTTATCCCCACATAGGTAATCTAGCGTTAGCCGATACTGATACACGGCACTGGCTAAAAGCGCTGGATGCT
GTAAGCAAAAATCACCCTGTGACTGCTGGTAGGTTATTGCAGATATGCAAGCAAGCCCTCAAATATTGCTATGTGCGCCG
CTACGGGGCTTGTGATGCCTTAAGTATGCTCACGGTGCAGGATGTTGGAAAGAACGCTGAAAGGCGGGATAGGGTGCTTA
CTGATAGAGAGGTGGCGGATGTATGGAGTAGCCTCGATAGAAAAGACATCATGCCTTACTATCGTGTCCTGACTCGTGTG
CTTCTTGTCTTTGGGTGTAGAACCAAAGAGGCCCGGTTATCCACATGGAAAGAGTGGGATCTGGATTCATGGGTCTGGAC
TGTACCTAAAGAGAATAGCAAAACCCGGGAAAAGATATTGCGTCCCATTCCTGAACCGTTGCGTGATTGGATTCAGACGT
TATATGACCAGAAGATATCTGATTTATTCATGGGTGAGTTGAAGTCTGAAAGCGCTGTTAGCCAGATAGGGCGAACACTT
CACAGAACGCTTAATCACTCTGAGTCATGGTCGTTTCATGACCTACGCCGGGCGCTATCAACTAATTTCAGCAATATGGG
TATAGCCCCGCATATATCAGAGATGATCCTCGGACATAAACTACCGGCGATAATGAGCAATTATAATTATGGGCAGTATT
TGCCTGAGAAACTGGACGCACTGAACAAGTGGATAGAGCGCTTGGATGTGCTGGCCGGCAATCATGAAAATGTGGTTTTG
CTATCACCAAACAAAACGGCGTAA

Upstream 100 bases:

>100_bases
CAATTATTAAGAGTGATAGTGTGACCTGATGTTGTTTACTGTTTTCGGGTTCATACAATGAACGGTGTATCACTCGGTGT
ATCACTTTTTGAAGGCGTTT

Downstream 100 bases:

>100_bases
ACTGTAAATAGCGGGGCTAGGTCGGCCAACCGAAAAGCGGGAAACCCTACCCGCCTGTCTCGCTAAACTTTAATATAGGG
GCGTTAAGGGCGACGAGAAT

Product: integrase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 406

Protein sequence:

>407_residues
MAGTNKLSDKKLKSLHCINSDSVKMFADGAGLSAKVSAQGSISWVFTYRLGGRESKLERLVFGRYPDMTLKAARDRRDQC
RTWLAGGCDPRRQLLEDVTQTLKPVTVKDALLYWVDNYAQTNRSDVDSIRSQFATYIYPHIGNLALADTDTRHWLKALDA
VSKNHPVTAGRLLQICKQALKYCYVRRYGACDALSMLTVQDVGKNAERRDRVLTDREVADVWSSLDRKDIMPYYRVLTRV
LLVFGCRTKEARLSTWKEWDLDSWVWTVPKENSKTREKILRPIPEPLRDWIQTLYDQKISDLFMGELKSESAVSQIGRTL
HRTLNHSESWSFHDLRRALSTNFSNMGIAPHISEMILGHKLPAIMSNYNYGQYLPEKLDALNKWIERLDVLAGNHENVVL
LSPNKTA

Sequences:

>Translated_407_residues
MAGTNKLSDKKLKSLHCINSDSVKMFADGAGLSAKVSAQGSISWVFTYRLGGRESKLERLVFGRYPDMTLKAARDRRDQC
RTWLAGGCDPRRQLLEDVTQTLKPVTVKDALLYWVDNYAQTNRSDVDSIRSQFATYIYPHIGNLALADTDTRHWLKALDA
VSKNHPVTAGRLLQICKQALKYCYVRRYGACDALSMLTVQDVGKNAERRDRVLTDREVADVWSSLDRKDIMPYYRVLTRV
LLVFGCRTKEARLSTWKEWDLDSWVWTVPKENSKTREKILRPIPEPLRDWIQTLYDQKISDLFMGELKSESAVSQIGRTL
HRTLNHSESWSFHDLRRALSTNFSNMGIAPHISEMILGHKLPAIMSNYNYGQYLPEKLDALNKWIERLDVLAGNHENVVL
LSPNKTA
>Mature_406_residues
AGTNKLSDKKLKSLHCINSDSVKMFADGAGLSAKVSAQGSISWVFTYRLGGRESKLERLVFGRYPDMTLKAARDRRDQCR
TWLAGGCDPRRQLLEDVTQTLKPVTVKDALLYWVDNYAQTNRSDVDSIRSQFATYIYPHIGNLALADTDTRHWLKALDAV
SKNHPVTAGRLLQICKQALKYCYVRRYGACDALSMLTVQDVGKNAERRDRVLTDREVADVWSSLDRKDIMPYYRVLTRVL
LVFGCRTKEARLSTWKEWDLDSWVWTVPKENSKTREKILRPIPEPLRDWIQTLYDQKISDLFMGELKSESAVSQIGRTLH
RTLNHSESWSFHDLRRALSTNFSNMGIAPHISEMILGHKLPAIMSNYNYGQYLPEKLDALNKWIERLDVLAGNHENVVLL
SPNKTA

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI145693166, Length=382, Percent_Identity=25.6544502617801, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1788974, Length=412, Percent_Identity=21.8446601941748, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 46641; Mature: 46510

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGTNKLSDKKLKSLHCINSDSVKMFADGAGLSAKVSAQGSISWVFTYRLGGRESKLERL
CCCCCCCCHHHHHHHHCCCCCCEEEEECCCCCEEEEECCCCEEEEEEEEECCCHHHHHHH
VFGRYPDMTLKAARDRRDQCRTWLAGGCDPRRQLLEDVTQTLKPVTVKDALLYWVDNYAQ
HHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
TNRSDVDSIRSQFATYIYPHIGNLALADTDTRHWLKALDAVSKNHPVTAGRLLQICKQAL
CCCHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
KYCYVRRYGACDALSMLTVQDVGKNAERRDRVLTDREVADVWSSLDRKDIMPYYRVLTRV
HHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHH
LLVFGCRTKEARLSTWKEWDLDSWVWTVPKENSKTREKILRPIPEPLRDWIQTLYDQKIS
HHHHCCCCCHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHH
DLFMGELKSESAVSQIGRTLHRTLNHSESWSFHDLRRALSTNFSNMGIAPHISEMILGHK
HHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHC
LPAIMSNYNYGQYLPEKLDALNKWIERLDVLAGNHENVVLLSPNKTA
CHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCC
>Mature Secondary Structure 
AGTNKLSDKKLKSLHCINSDSVKMFADGAGLSAKVSAQGSISWVFTYRLGGRESKLERL
CCCCCCCHHHHHHHHCCCCCCEEEEECCCCCEEEEECCCCEEEEEEEEECCCHHHHHHH
VFGRYPDMTLKAARDRRDQCRTWLAGGCDPRRQLLEDVTQTLKPVTVKDALLYWVDNYAQ
HHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
TNRSDVDSIRSQFATYIYPHIGNLALADTDTRHWLKALDAVSKNHPVTAGRLLQICKQAL
CCCHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
KYCYVRRYGACDALSMLTVQDVGKNAERRDRVLTDREVADVWSSLDRKDIMPYYRVLTRV
HHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHH
LLVFGCRTKEARLSTWKEWDLDSWVWTVPKENSKTREKILRPIPEPLRDWIQTLYDQKIS
HHHHCCCCCHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHH
DLFMGELKSESAVSQIGRTLHRTLNHSESWSFHDLRRALSTNFSNMGIAPHISEMILGHK
HHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHC
LPAIMSNYNYGQYLPEKLDALNKWIERLDVLAGNHENVVLLSPNKTA
CHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]