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The map label for this gene is secM

Identifier: 170025725

GI number: 170025725

Start: 3855977

End: 3856441

Strand: Reverse

Name: secM

Synonym: YPK_3510

Alternate gene names: 170025725

Gene position: 3856441-3855977 (Counterclockwise)

Preceding gene: 170025727

Following gene: 170025724

Centisome position: 82.24

GC content: 50.75

Gene sequence:

>465_bases
ATGGTCGCGGCGAGTCTTGGTGTGCCATCAAATCTGTCTGGCGTTCCAGACCATGCGGCATTAGCGAACACATCATCCAG
CCAAAGTCGTCAGAATCATGGTACGACAAACTTCAACAGTTTGGCACTGTTGCATGACATACACCGTCGCCCCTCATTCA
GTGTAGATTACTGGCAACAGCATGCCCTGCGCACGGTCATCCGTCACCTCTCTTTTGCTCTGGCACCACAAGCGGCATAT
GCACGCGTACAAGAAGTCGCCGAAACAGAACGGGTTGCTCCATCAAAAATTCAGCAACTCGCGTTACTGGATACGCTAAA
TGCACTACTGACGCATGAATTTAAGCCACCGGCCATTATTCGCTATACAGAACAGGTTGAACGGCCTGTTCTGTCGCCAT
ATAAACCTGGGCTCTGGCTTGCTCAAGTACAAGGTATTCGTGCCGGTCCTGCCAACTTAAGCTAA

Upstream 100 bases:

>100_bases
CATTGACAAGGCTCCGGCGGATTTTAAACTCGTGATCGGTATTCTAAATCGTTGGCGACAATTTGGCAGACGTTATTTCT
GGCCGCATCTCCTGTTGGGG

Downstream 100 bases:

>100_bases
TTATTCTCTTGGTTTATCCCAATTTTATACAACCTTTGGCCGCCGGTTTGGTGGTCTTGTAAGAGATATTAAGAATCATG
CTAATCAAATTATTAACCAA

Product: SecA regulator SecM

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MVAASLGVPSNLSGVPDHAALANTSSSQSRQNHGTTNFNSLALLHDIHRRPSFSVDYWQQHALRTVIRHLSFALAPQAAY
ARVQEVAETERVAPSKIQQLALLDTLNALLTHEFKPPAIIRYTEQVERPVLSPYKPGLWLAQVQGIRAGPANLS

Sequences:

>Translated_154_residues
MVAASLGVPSNLSGVPDHAALANTSSSQSRQNHGTTNFNSLALLHDIHRRPSFSVDYWQQHALRTVIRHLSFALAPQAAY
ARVQEVAETERVAPSKIQQLALLDTLNALLTHEFKPPAIIRYTEQVERPVLSPYKPGLWLAQVQGIRAGPANLS
>Mature_154_residues
MVAASLGVPSNLSGVPDHAALANTSSSQSRQNHGTTNFNSLALLHDIHRRPSFSVDYWQQHALRTVIRHLSFALAPQAAY
ARVQEVAETERVAPSKIQQLALLDTLNALLTHEFKPPAIIRYTEQVERPVLSPYKPGLWLAQVQGIRAGPANLS

Specific function: Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm, cytosol. Periplasm (By similarity). Note=The active form is cytosolic, while the periplasmic form is rapidly degraded, mainly by the tail-specific protease (By similarity)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secM family

Homologues:

Organism=Escherichia coli, GI87081686, Length=159, Percent_Identity=44.6540880503145, Blast_Score=105, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SECM_YERP3 (A7FM58)

Other databases:

- EMBL:   CP000720
- RefSeq:   YP_001402336.1
- STRING:   A7FM58
- GeneID:   5384702
- GenomeReviews:   CP000720_GR
- KEGG:   ypi:YpsIP31758_3379
- eggNOG:   NOG07544
- HOGENOM:   HBG416690
- OMA:   FAMAPQA
- ProtClustDB:   PRK02943
- BioCyc:   YPSE349747:YPSIP31758_3379-MONOMER
- GO:   GO:0005829
- HAMAP:   MF_01332
- InterPro:   IPR009502
- PIRSF:   PIRSF004572
- ProDom:   PD089227

Pfam domain/function: PF06558 SecM

EC number: NA

Molecular weight: Translated: 16892; Mature: 16892

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAASLGVPSNLSGVPDHAALANTSSSQSRQNHGTTNFNSLALLHDIHRRPSFSVDYWQQ
CCCCCCCCCCCCCCCCCHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHH
HALRTVIRHLSFALAPQAAYARVQEVAETERVAPSKIQQLALLDTLNALLTHEFKPPAII
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHH
RYTEQVERPVLSPYKPGLWLAQVQGIRAGPANLS
HHHHHHCCCCCCCCCCCEEHHHHCCCCCCCCCCC
>Mature Secondary Structure
MVAASLGVPSNLSGVPDHAALANTSSSQSRQNHGTTNFNSLALLHDIHRRPSFSVDYWQQ
CCCCCCCCCCCCCCCCCHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHH
HALRTVIRHLSFALAPQAAYARVQEVAETERVAPSKIQQLALLDTLNALLTHEFKPPAII
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHH
RYTEQVERPVLSPYKPGLWLAQVQGIRAGPANLS
HHHHHHCCCCCCCCCCCEEHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA