| Definition | Yersinia pseudotuberculosis YPIII chromosome, complete genome. |
|---|---|
| Accession | NC_010465 |
| Length | 4,689,441 |
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The map label for this gene is cysG1 [H]
Identifier: 170025652
GI number: 170025652
Start: 3769409
End: 3770827
Strand: Reverse
Name: cysG1 [H]
Synonym: YPK_3437
Alternate gene names: 170025652
Gene position: 3770827-3769409 (Counterclockwise)
Preceding gene: 170025655
Following gene: 170025651
Centisome position: 80.41
GC content: 55.74
Gene sequence:
>1419_bases GTGGACTATCTACCTCTATTTGCCGACTTGAAACAACGCCCGGTATTGATCGTTGGCGGCGGCGAAGTTGCTGCGCGAAA AATTGAACTACTGCACCGCGCAGGTGCGCAGGTATGGGTAGTGGCGCAAACCCTCTCATCTGAACTCGAACAGCAGTATC AGGATGGCCGTATCCATTGGCTGGCACAGGATTTTCTGCCTGAACAGTTGGACAACGTGTTTCTGGTGATTGCCGCAACT AACGATACCGTACTGAATGCCGCTGTTTTCGCGGCGGCAGATCAACGGTGTATTTTGGCGAATGTGGTGGATGACCAACC CCTTTGTTCGTTTATTTTCCCTTCGATTGTTGATCGTTCACCGCTGGTGGTCGCGATCTCGTCTTCCGGCCAGGCACCGG TGCTGGCGCGGATACTGCGTGAGAAGTTAGAAGCCTTACTGCCCACTCGTCTCAGTGATATGGCCGCTATAGCTGGGCGC TGGCGTGGGCGGGTTAAGCAGCATATGACCTCTATGGGGGAGCGCCGCCGCTTTTGGGAACATGCATTCAGCGGGCGCTT TGCCAGCCTTATCAGCCGTGGTCAGTTAACCGAGGCTGAAAATGAATTACAACTGTCGCTAGAGGGCCAACACCGTGCAC TCGGCGAAGTGGCTTTGGTCGGTGCAGGTCCTGGCGATGCAGGGTTATTAACGTTACGTGGTTTGCAAGTGATGCAGCAG GCAGATGTGGTGCTGTATGACCATTTAGTCAGTCCGGAAGTCTTGGATTTGGTGCGTCGCGATGCTGAACGCATCTGTGT GGGGAAACGGGCGGGGGCGCATTCGGTTACCCAAGAGGCAACCAATCAGTTGTTGGTCACTCTGGCACAGCAAGGAAAAC GGGTCGTACGGCTAAAAGGTGGCGATCCCTTTATTTTTGGTCGGGGGGGGGAAGAGTTACAAGTTGTGGCGCAAGCGGGG ATCCCGTTTCAGGTGGTACCGGGGGTGACGGCTGCTGCGGGGGCGACAGCCTATGCCGGTATTCCCCTGACACACCGCGA TCATGCGCAAAGCGTGACATTTATTACCGGGCATTGCCGTCCTGATGGCGATGATCTTGATTGGCAGGCGCTGGCCCGTG GTCGTCAGACGCTGGCGATCTACATGGGAACAGTGAAAGCGGCGGCAATCAGCCAACAGTTGATCGCCCATGGCCGGTCC AGTACCACGCCGGTGGCAGTGATTGGCCGTGGAACCCGTGTGGACCAGCAGGTGCTGATCGGTACGTTGGCACAACTTGA ATCACTCGCACAGCAGGCACCGACACCAGCACTACTGGTGATTGGTGAAGTGGTGAATTTACATCACCAAATTGCCTGGT TTGGGCAACAACCGCAGACTGAATCGGCGATCAGCCCATCAGTCGTGAATTTGGCATAA
Upstream 100 bases:
>100_bases ATATATCATTATGGAACTTGTAATTACTTTTCGTCATTTCATAAGGTCATGGCCCCCCCCTATAGTCACCCTACGCTTTA TCATGTAATCGAAGGCTGTT
Downstream 100 bases:
>100_bases AGGATCTGTTATGGACGAAAAACGACTCACTCATTTACGGCAATTGGAGGCGGAGAGTATCCATATCATCCGTGAAGTGG CCGCTGAATTCGGTAACCCG
Product: uroporphyrin-III C-methyltransferase
Products: NA
Alternate protein names: Uroporphyrinogen-III C-methyltransferase; Urogen III methylase; SUMT; Uroporphyrinogen III methylase; UROM; Precorrin-2 dehydrogenase; Sirohydrochlorin ferrochelatase [H]
Number of amino acids: Translated: 472; Mature: 472
Protein sequence:
>472_residues MDYLPLFADLKQRPVLIVGGGEVAARKIELLHRAGAQVWVVAQTLSSELEQQYQDGRIHWLAQDFLPEQLDNVFLVIAAT NDTVLNAAVFAAADQRCILANVVDDQPLCSFIFPSIVDRSPLVVAISSSGQAPVLARILREKLEALLPTRLSDMAAIAGR WRGRVKQHMTSMGERRRFWEHAFSGRFASLISRGQLTEAENELQLSLEGQHRALGEVALVGAGPGDAGLLTLRGLQVMQQ ADVVLYDHLVSPEVLDLVRRDAERICVGKRAGAHSVTQEATNQLLVTLAQQGKRVVRLKGGDPFIFGRGGEELQVVAQAG IPFQVVPGVTAAAGATAYAGIPLTHRDHAQSVTFITGHCRPDGDDLDWQALARGRQTLAIYMGTVKAAAISQQLIAHGRS STTPVAVIGRGTRVDQQVLIGTLAQLESLAQQAPTPALLVIGEVVNLHHQIAWFGQQPQTESAISPSVVNLA
Sequences:
>Translated_472_residues MDYLPLFADLKQRPVLIVGGGEVAARKIELLHRAGAQVWVVAQTLSSELEQQYQDGRIHWLAQDFLPEQLDNVFLVIAAT NDTVLNAAVFAAADQRCILANVVDDQPLCSFIFPSIVDRSPLVVAISSSGQAPVLARILREKLEALLPTRLSDMAAIAGR WRGRVKQHMTSMGERRRFWEHAFSGRFASLISRGQLTEAENELQLSLEGQHRALGEVALVGAGPGDAGLLTLRGLQVMQQ ADVVLYDHLVSPEVLDLVRRDAERICVGKRAGAHSVTQEATNQLLVTLAQQGKRVVRLKGGDPFIFGRGGEELQVVAQAG IPFQVVPGVTAAAGATAYAGIPLTHRDHAQSVTFITGHCRPDGDDLDWQALARGRQTLAIYMGTVKAAAISQQLIAHGRS STTPVAVIGRGTRVDQQVLIGTLAQLESLAQQAPTPALLVIGEVVNLHHQIAWFGQQPQTESAISPSVVNLA >Mature_472_residues MDYLPLFADLKQRPVLIVGGGEVAARKIELLHRAGAQVWVVAQTLSSELEQQYQDGRIHWLAQDFLPEQLDNVFLVIAAT NDTVLNAAVFAAADQRCILANVVDDQPLCSFIFPSIVDRSPLVVAISSSGQAPVLARILREKLEALLPTRLSDMAAIAGR WRGRVKQHMTSMGERRRFWEHAFSGRFASLISRGQLTEAENELQLSLEGQHRALGEVALVGAGPGDAGLLTLRGLQVMQQ ADVVLYDHLVSPEVLDLVRRDAERICVGKRAGAHSVTQEATNQLLVTLAQQGKRVVRLKGGDPFIFGRGGEELQVVAQAG IPFQVVPGVTAAAGATAYAGIPLTHRDHAQSVTFITGHCRPDGDDLDWQALARGRQTLAIYMGTVKAAAISQQLIAHGRS STTPVAVIGRGTRVDQQVLIGTLAQLESLAQQAPTPALLVIGEVVNLHHQIAWFGQQPQTESAISPSVVNLA
Specific function: Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into si
COG id: COG0007
COG function: function code H; Uroporphyrinogen-III methylase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the precorrin methyltransferase family [H]
Homologues:
Organism=Escherichia coli, GI1789768, Length=460, Percent_Identity=56.0869565217391, Blast_Score=476, Evalue=1e-135, Organism=Saccharomyces cerevisiae, GI6322922, Length=255, Percent_Identity=34.5098039215686, Blast_Score=127, Evalue=5e-30,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR000878 - InterPro: IPR014777 - InterPro: IPR014776 - InterPro: IPR006366 - InterPro: IPR016040 - InterPro: IPR019478 - InterPro: IPR006367 - InterPro: IPR003043 [H]
Pfam domain/function: PF10414 CysG_dimeriser; PF00590 TP_methylase [H]
EC number: =2.1.1.107; =1.3.1.76; =4.99.1.4 [H]
Molecular weight: Translated: 50905; Mature: 50905
Theoretical pI: Translated: 6.85; Mature: 6.85
Prosite motif: PS00839 SUMT_1 ; PS00840 SUMT_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 1.3 %Met (Translated Protein) 2.1 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 1.3 %Met (Mature Protein) 2.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDYLPLFADLKQRPVLIVGGGEVAARKIELLHRAGAQVWVVAQTLSSELEQQYQDGRIHW CCCCCCHHHHCCCCEEEEECCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCEEE LAQDFLPEQLDNVFLVIAATNDTVLNAAVFAAADQRCILANVVDDQPLCSFIFPSIVDRS EHHHHCHHHCCCEEEEEEECCCCHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHCCCC PLVVAISSSGQAPVLARILREKLEALLPTRLSDMAAIAGRWRGRVKQHMTSMGERRRFWE CEEEEECCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH HAFSGRFASLISRGQLTEAENELQLSLEGQHRALGEVALVGAGPGDAGLLTLRGLQVMQQ HHHCCHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHH ADVVLYDHLVSPEVLDLVRRDAERICVGKRAGAHSVTQEATNQLLVTLAQQGKRVVRLKG CCCCEEHHCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEC GDPFIFGRGGEELQVVAQAGIPFQVVPGVTAAAGATAYAGIPLTHRDHAQSVTFITGHCR CCEEEECCCCCEEEEEEECCCCEEECCCCCHHCCCCCCCCCCCCCCCCCCEEEEEEEECC PDGDDLDWQALARGRQTLAIYMGTVKAAAISQQLIAHGRSSTTPVAVIGRGTRVDQQVLI CCCCCCCHHHHHCCCCEEEEEEHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHH GTLAQLESLAQQAPTPALLVIGEVVNLHHQIAWFGQQPQTESAISPSVVNLA HHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCC >Mature Secondary Structure MDYLPLFADLKQRPVLIVGGGEVAARKIELLHRAGAQVWVVAQTLSSELEQQYQDGRIHW CCCCCCHHHHCCCCEEEEECCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCEEE LAQDFLPEQLDNVFLVIAATNDTVLNAAVFAAADQRCILANVVDDQPLCSFIFPSIVDRS EHHHHCHHHCCCEEEEEEECCCCHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHCCCC PLVVAISSSGQAPVLARILREKLEALLPTRLSDMAAIAGRWRGRVKQHMTSMGERRRFWE CEEEEECCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH HAFSGRFASLISRGQLTEAENELQLSLEGQHRALGEVALVGAGPGDAGLLTLRGLQVMQQ HHHCCHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHH ADVVLYDHLVSPEVLDLVRRDAERICVGKRAGAHSVTQEATNQLLVTLAQQGKRVVRLKG CCCCEEHHCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEC GDPFIFGRGGEELQVVAQAGIPFQVVPGVTAAAGATAYAGIPLTHRDHAQSVTFITGHCR CCEEEECCCCCEEEEEEECCCCEEECCCCCHHCCCCCCCCCCCCCCCCCCEEEEEEEECC PDGDDLDWQALARGRQTLAIYMGTVKAAAISQQLIAHGRSSTTPVAVIGRGTRVDQQVLI CCCCCCCHHHHHCCCCEEEEEEHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHH GTLAQLESLAQQAPTPALLVIGEVVNLHHQIAWFGQQPQTESAISPSVVNLA HHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA