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The map label for this gene is arsR [H]

Identifier: 170025630

GI number: 170025630

Start: 3747472

End: 3747813

Strand: Direct

Name: arsR [H]

Synonym: YPK_3415

Alternate gene names: 170025630

Gene position: 3747472-3747813 (Clockwise)

Preceding gene: 170025629

Following gene: 170025631

Centisome position: 79.91

GC content: 48.83

Gene sequence:

>342_bases
ATGACAACACTCACGCCGTTGCAACTTTTTAAGAACTTATCGGATGAAACACGTCTGAATATTATCTTATTGCTAAAAGC
ATCCGGCGAACTGTGTGTTTGTGAGCTTTGCCATCGCTTAAATGAAGCCCAACCCAAGATTTCCAGGCACTTAGCCATGC
TAAGAGCGTCCGGGCTGTTACTGGATCGCCGGGCCGGGAAATGGGTCCACTACCGCCTGTCGCCCCATATTCCAGCCTGG
GCCGCAGCCATCATTGAGCAAACTTATCTCAGCCAACGCGATGAAATAACGTTACTGACGCAGGGTAACGTCACTCCTGA
CAGCAAAATGTTGTGTAACTAA

Upstream 100 bases:

>100_bases
CCCTCCCCGCGCCCAATACACATTTGAAAAAACAAATATGAAATTGACATTCTCTCGTTGAACACTAAGATAGCGGAGAA
AAATTCATTCAGGGAGCATC

Downstream 100 bases:

>100_bases
CCTATTTAAAATTTACCTAATTATATCTGTTTTTCCATATGTGAATGAATGGAACGACACACTATTTAACTCAGCGGAGG
CGTTATGTTGTTGGCAGGTG

Product: DNA-binding transcriptional repressor ArsR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 113; Mature: 112

Protein sequence:

>113_residues
MTTLTPLQLFKNLSDETRLNIILLLKASGELCVCELCHRLNEAQPKISRHLAMLRASGLLLDRRAGKWVHYRLSPHIPAW
AAAIIEQTYLSQRDEITLLTQGNVTPDSKMLCN

Sequences:

>Translated_113_residues
MTTLTPLQLFKNLSDETRLNIILLLKASGELCVCELCHRLNEAQPKISRHLAMLRASGLLLDRRAGKWVHYRLSPHIPAW
AAAIIEQTYLSQRDEITLLTQGNVTPDSKMLCN
>Mature_112_residues
TTLTPLQLFKNLSDETRLNIILLLKASGELCVCELCHRLNEAQPKISRHLAMLRASGLLLDRRAGKWVHYRLSPHIPAWA
AAIIEQTYLSQRDEITLLTQGNVTPDSKMLCN

Specific function: Transcriptional repressor for the ars operon. ArsR is a trans-acting regulatory protein which controls its own expression. The repressive effect of ArsR is alleviated by oxyions of +III oxidation state of arsenic, antimony, and bismuth, as well as arsenat

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789916, Length=117, Percent_Identity=58.974358974359, Blast_Score=145, Evalue=7e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR018334
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 12793; Mature: 12662

Theoretical pI: Translated: 8.67; Mature: 8.67

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLTPLQLFKNLSDETRLNIILLLKASGELCVCELCHRLNEAQPKISRHLAMLRASGLL
CCCCCHHHHHHCCCCCCEEEEEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCEE
LDRRAGKWVHYRLSPHIPAWAAAIIEQTYLSQRDEITLLTQGNVTPDSKMLCN
EECCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCC
>Mature Secondary Structure 
TTLTPLQLFKNLSDETRLNIILLLKASGELCVCELCHRLNEAQPKISRHLAMLRASGLL
CCCCHHHHHHCCCCCCEEEEEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCEE
LDRRAGKWVHYRLSPHIPAWAAAIIEQTYLSQRDEITLLTQGNVTPDSKMLCN
EECCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2408017; 1838573; 8416957 [H]