Click here to switch to the map view.

The map label for this gene is pheC [H]

Identifier: 170025627

GI number: 170025627

Start: 3745360

End: 3746124

Strand: Direct

Name: pheC [H]

Synonym: YPK_3412

Alternate gene names: 170025627

Gene position: 3745360-3746124 (Clockwise)

Preceding gene: 170025626

Following gene: 170025628

Centisome position: 79.87

GC content: 43.79

Gene sequence:

>765_bases
ATGAAAAAATTATCTTTGGGAATAATGGTATTGGCATTAATCAGTAGCCAACACGTATTAGCAAAAAATTGGCAGGAAAT
TAAGCAAAGTGGTGAGCTGCGTATTGGGGTACCAGGTGACTATGCGCCTTTAGCTTTCCATGATAAACAGGGCCAATTGA
TCGGCTACGATGTTGATATGGCAAACGCCTTGGGTGCCAACCTGAAACTGAAGGTTAATTTTGTTTCGACCAGTTGGCCA
ACTCTTTCAGACGATTTGGCGGCAGATAAATTTGATATTGCCATGGGGGGCGTCACGGCGACACCCGGTAGAGAAGCGCA
ATTTGCTTTATCCCACGCCGTCGTGAAAAATGGGAAAATTGCGCTGACCCATTGCCAGAAAGTCAATAAATTCCCCACGC
TTGATGCGATTGATCGTCAAAACGTCAAAGTTATTGTCAACCCTGGCGGTACCAACCAATCGTTTGTTGATGCAAATATT
AAGCAAGCGCAAATCATCCGAACCAAAGATAACGTTGCTAACCTGCAAGGTATACGTGATAAAAGTGCAGATATTATGTT
CACTGACTTAATCGAAGGCGATTATTATCAGAGCAAAGAACCTGGCGTATTTTGTGTCGCCACCCCAGAGGTTTTAGCCG
GAACGGGCAGCTACAAAGTTTATATGATGGCTAAGGATAATCAGCCGTTGTTAGAAGAAGTTAACCAGTGGCTGGCCGGG
AAGACCAAAACCTTATTAGCACAAAAGTGGAATATTTCTGAGTAG

Upstream 100 bases:

>100_bases
TTGACCGGGGAATATATTCCTCATTCCTGAGCAATATACAGTAGGATAATTTACCCTGATTGACCTTAATGGGCTCTTAT
AAAAAATAACAGGAATGCAG

Downstream 100 bases:

>100_bases
CCAGTAAGAGGCGATGGCCGTTTATTACAGCACTCTTCGCTTAGTAAACGGTCTGCCCGATATCATCTTCAATAGTCACC
ACAAAAAAACAGAAAAATAC

Product: arogenate dehydratase

Products: NA

Alternate protein names: Prephenate dehydratase; Arogenate dehydratase [H]

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MKKLSLGIMVLALISSQHVLAKNWQEIKQSGELRIGVPGDYAPLAFHDKQGQLIGYDVDMANALGANLKLKVNFVSTSWP
TLSDDLAADKFDIAMGGVTATPGREAQFALSHAVVKNGKIALTHCQKVNKFPTLDAIDRQNVKVIVNPGGTNQSFVDANI
KQAQIIRTKDNVANLQGIRDKSADIMFTDLIEGDYYQSKEPGVFCVATPEVLAGTGSYKVYMMAKDNQPLLEEVNQWLAG
KTKTLLAQKWNISE

Sequences:

>Translated_254_residues
MKKLSLGIMVLALISSQHVLAKNWQEIKQSGELRIGVPGDYAPLAFHDKQGQLIGYDVDMANALGANLKLKVNFVSTSWP
TLSDDLAADKFDIAMGGVTATPGREAQFALSHAVVKNGKIALTHCQKVNKFPTLDAIDRQNVKVIVNPGGTNQSFVDANI
KQAQIIRTKDNVANLQGIRDKSADIMFTDLIEGDYYQSKEPGVFCVATPEVLAGTGSYKVYMMAKDNQPLLEEVNQWLAG
KTKTLLAQKWNISE
>Mature_254_residues
MKKLSLGIMVLALISSQHVLAKNWQEIKQSGELRIGVPGDYAPLAFHDKQGQLIGYDVDMANALGANLKLKVNFVSTSWP
TLSDDLAADKFDIAMGGVTATPGREAQFALSHAVVKNGKIALTHCQKVNKFPTLDAIDRQNVKVIVNPGGTNQSFVDANI
KQAQIIRTKDNVANLQGIRDKSADIMFTDLIEGDYYQSKEPGVFCVATPEVLAGTGSYKVYMMAKDNQPLLEEVNQWLAG
KTKTLLAQKWNISE

Specific function: Forms alternative pathway for phenylalanine biosynthesis. Can catalyze two reactions:prephenate dehydratase and arogenate dehydratase. May have a role in chemotaxis or transport [H]

COG id: COG0834

COG function: function code ET; ABC-type amino acid transport/signal transduction systems, periplasmic component/domain

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 3 family [H]

Homologues:

Organism=Escherichia coli, GI1788228, Length=255, Percent_Identity=25.0980392156863, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: 1920 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1060 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 80 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015683
- InterPro:   IPR001638
- InterPro:   IPR018313 [H]

Pfam domain/function: PF00497 SBP_bac_3 [H]

EC number: =4.2.1.51; =4.2.1.91 [H]

Molecular weight: Translated: 27764; Mature: 27764

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: PS01039 SBP_BACTERIAL_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLSLGIMVLALISSQHVLAKNWQEIKQSGELRIGVPGDYAPLAFHDKQGQLIGYDVDM
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEECCCCCCCEEEECCCCCEEEEECCH
ANALGANLKLKVNFVSTSWPTLSDDLAADKFDIAMGGVTATPGREAQFALSHAVVKNGKI
HHHCCCCEEEEEEEEECCCCCCCCCCCCCEEEEEECCEECCCCCCHHHHHHHHHHCCCCE
ALTHCQKVNKFPTLDAIDRQNVKVIVNPGGTNQSFVDANIKQAQIIRTKDNVANLQGIRD
EEEEHHHCCCCCCCCCCCCCCCEEEECCCCCCCCEEECCCCEEEEEECCCCHHHHCCCCC
KSADIMFTDLIEGDYYQSKEPGVFCVATPEVLAGTGSYKVYMMAKDNQPLLEEVNQWLAG
CCCCEEEEEEECCCCCCCCCCCEEEEECHHHHCCCCCEEEEEEECCCCHHHHHHHHHHCC
KTKTLLAQKWNISE
CHHEEEEECCCCCC
>Mature Secondary Structure
MKKLSLGIMVLALISSQHVLAKNWQEIKQSGELRIGVPGDYAPLAFHDKQGQLIGYDVDM
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEECCCCCCCEEEECCCCCEEEEECCH
ANALGANLKLKVNFVSTSWPTLSDDLAADKFDIAMGGVTATPGREAQFALSHAVVKNGKI
HHHCCCCEEEEEEEEECCCCCCCCCCCCCEEEEEECCEECCCCCCHHHHHHHHHHCCCCE
ALTHCQKVNKFPTLDAIDRQNVKVIVNPGGTNQSFVDANIKQAQIIRTKDNVANLQGIRD
EEEEHHHCCCCCCCCCCCCCCCEEEECCCCCCCCEEECCCCEEEEEECCCCHHHHCCCCC
KSADIMFTDLIEGDYYQSKEPGVFCVATPEVLAGTGSYKVYMMAKDNQPLLEEVNQWLAG
CCCCEEEEEEECCCCCCCCCCCEEEEECHHHHCCCCCEEEEEEECCCCHHHHHHHHHHCC
KTKTLLAQKWNISE
CHHEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1733946; 10984043; 8515238; 7604006 [H]