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The map label for this gene is yrbE [H]

Identifier: 170025263

GI number: 170025263

Start: 3343208

End: 3344341

Strand: Reverse

Name: yrbE [H]

Synonym: YPK_3042

Alternate gene names: 170025263

Gene position: 3344341-3343208 (Counterclockwise)

Preceding gene: 170025264

Following gene: 170025262

Centisome position: 71.32

GC content: 56.26

Gene sequence:

>1134_bases
ATGAAAGAAGTGCGTATTGGATTGATTGGTACCGGGTATATCGGTAAGGCGCACGCCATTGCCTACGCACAGGCACCGAC
GGTGTTTGAATTGCGCGGCAAACTGGTGCGCGAAATGGTGGCCGAAGTCTCACCAGCGCTGGCGGCACAGCGTGCGCAGG
CTTTCGGTTTCAACCGGTTTACCTGCGACTGGCGGGAGCTGGTCGCGGATCCGGCTATTGATGTGGTTGATATTTGCTCA
CCTAATTATCTACATAAAGAGATGGCGCTGGCGGCCATTCACCACGGCAAACATGTCTATGCGGAGAAACCGCTGGCGCT
GAATGCCCGTGACGCCAGCGAGATGGCGGCGGCCGCAACGCGCGCTGGGGTGAAAACGTTGGTAGGGTTCAATTACATCA
AAAACCCCAGTGCGAAGCTGGCTAAAGAGATCATTGAACGTGGTGAAATCGGTGAGGTGATCCACTTTTATGGCACCCAT
AACGAAGACTATATGGCCGATCCCAATACCCCTATTCACTGGCACTGTTTACAAGCGACGGCAGGGCTGGGAGCACTTGG
CGATCTGGCGGCCCACATCGTCAGCATGGCGCAATATCTGGTGGGGGAAATAACGCAGGTATGCGGTGATCTGAAAACCG
TCGTGGTGACACGCCCGGCGAGCGTTGGCTCCAGCGCCAGAGTGGCGGTTGAAAACGAAGATCAGGCCCATGCCATGGTG
CGTTTTGTGAATGGCGCTCAGGGAGTGATTGAAGCCTCGCGGGTGGCTTGCGGGCGCAAAATGGGCCTCTCTTACATGAT
TACCGGTACTCAAGGGGCGATCAGTTTTACCCAAGAACGTATGGCGGAACTCAAACTCTACCTGCACAACGACCCGGTCA
ACCGACAAGGCTTCCGTACCCTGCTCGTCGGCCCGGCGCACCCAGAGTATGCCGCGTTCTGTATGGCTGCGGGCCACGGT
ATTGGTTTTAACGATCAAAAAACCGTGGAAGTGCGTGACTTGATCGACGGCATCGCGATGGACACGCCGCTGTGGCCCGA
TTTCGCCGAGGGCTGGAAAGTCTCACGCATTCTCGATGCGATTGCTCTGTCTCATCAGGATAGCCGCTGGGTGAATGTGA
CCGACATTGTCTGA

Upstream 100 bases:

>100_bases
AAATTATCACCGGCCTGATCATCGTATTGGCGGTGGCCTTTGATACCTACGCCAAGAACCGTCGCGGCGCGCTGTAATAC
GTTCATGTCAGGAGTGAATG

Downstream 100 bases:

>100_bases
GGATGGGGTATGTCTGAGGATGAGGTATGACAGGGTCTGAGGGGGGGTATGAGTGTGGAAAAGCAATTTAGCGTTAGCGC
GGAAAAGACATGTAATACGG

Product: oxidoreductase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MKEVRIGLIGTGYIGKAHAIAYAQAPTVFELRGKLVREMVAEVSPALAAQRAQAFGFNRFTCDWRELVADPAIDVVDICS
PNYLHKEMALAAIHHGKHVYAEKPLALNARDASEMAAAATRAGVKTLVGFNYIKNPSAKLAKEIIERGEIGEVIHFYGTH
NEDYMADPNTPIHWHCLQATAGLGALGDLAAHIVSMAQYLVGEITQVCGDLKTVVVTRPASVGSSARVAVENEDQAHAMV
RFVNGAQGVIEASRVACGRKMGLSYMITGTQGAISFTQERMAELKLYLHNDPVNRQGFRTLLVGPAHPEYAAFCMAAGHG
IGFNDQKTVEVRDLIDGIAMDTPLWPDFAEGWKVSRILDAIALSHQDSRWVNVTDIV

Sequences:

>Translated_377_residues
MKEVRIGLIGTGYIGKAHAIAYAQAPTVFELRGKLVREMVAEVSPALAAQRAQAFGFNRFTCDWRELVADPAIDVVDICS
PNYLHKEMALAAIHHGKHVYAEKPLALNARDASEMAAAATRAGVKTLVGFNYIKNPSAKLAKEIIERGEIGEVIHFYGTH
NEDYMADPNTPIHWHCLQATAGLGALGDLAAHIVSMAQYLVGEITQVCGDLKTVVVTRPASVGSSARVAVENEDQAHAMV
RFVNGAQGVIEASRVACGRKMGLSYMITGTQGAISFTQERMAELKLYLHNDPVNRQGFRTLLVGPAHPEYAAFCMAAGHG
IGFNDQKTVEVRDLIDGIAMDTPLWPDFAEGWKVSRILDAIALSHQDSRWVNVTDIV
>Mature_377_residues
MKEVRIGLIGTGYIGKAHAIAYAQAPTVFELRGKLVREMVAEVSPALAAQRAQAFGFNRFTCDWRELVADPAIDVVDICS
PNYLHKEMALAAIHHGKHVYAEKPLALNARDASEMAAAATRAGVKTLVGFNYIKNPSAKLAKEIIERGEIGEVIHFYGTH
NEDYMADPNTPIHWHCLQATAGLGALGDLAAHIVSMAQYLVGEITQVCGDLKTVVVTRPASVGSSARVAVENEDQAHAMV
RFVNGAQGVIEASRVACGRKMGLSYMITGTQGAISFTQERMAELKLYLHNDPVNRQGFRTLLVGPAHPEYAAFCMAAGHG
IGFNDQKTVEVRDLIDGIAMDTPLWPDFAEGWKVSRILDAIALSHQDSRWVNVTDIV

Specific function: Unknown

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Escherichia coli, GI87082405, Length=153, Percent_Identity=32.0261437908497, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI87081947, Length=271, Percent_Identity=25.0922509225092, Blast_Score=66, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6323975, Length=212, Percent_Identity=26.8867924528302, Blast_Score=66, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24581117, Length=283, Percent_Identity=25.4416961130742, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 40960; Mature: 40960

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEVRIGLIGTGYIGKAHAIAYAQAPTVFELRGKLVREMVAEVSPALAAQRAQAFGFNRF
CCCEEEEEEECCCCCCHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
TCDWRELVADPAIDVVDICSPNYLHKEMALAAIHHGKHVYAEKPLALNARDASEMAAAAT
CCCHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHCCCEEEECCCCEECCCCHHHHHHHHH
RAGVKTLVGFNYIKNPSAKLAKEIIERGEIGEVIHFYGTHNEDYMADPNTPIHWHCLQAT
HHHHHHHHCCHHCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCEEEEEEEHH
AGLGALGDLAAHIVSMAQYLVGEITQVCGDLKTVVVTRPASVGSSARVAVENEDQAHAMV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCEEEECCCCHHHHHH
RFVNGAQGVIEASRVACGRKMGLSYMITGTQGAISFTQERMAELKLYLHNDPVNRQGFRT
HHHCCCCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHEEEEEECCCCCCCCCEE
LLVGPAHPEYAAFCMAAGHGIGFNDQKTVEVRDLIDGIAMDTPLWPDFAEGWKVSRILDA
EEECCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHH
IALSHQDSRWVNVTDIV
HHHCCCCCCEEEEECCC
>Mature Secondary Structure
MKEVRIGLIGTGYIGKAHAIAYAQAPTVFELRGKLVREMVAEVSPALAAQRAQAFGFNRF
CCCEEEEEEECCCCCCHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
TCDWRELVADPAIDVVDICSPNYLHKEMALAAIHHGKHVYAEKPLALNARDASEMAAAAT
CCCHHHHHCCCCCCEEECCCCCHHHHHHHHHHHHCCCEEEECCCCEECCCCHHHHHHHHH
RAGVKTLVGFNYIKNPSAKLAKEIIERGEIGEVIHFYGTHNEDYMADPNTPIHWHCLQAT
HHHHHHHHCCHHCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCEEEEEEEHH
AGLGALGDLAAHIVSMAQYLVGEITQVCGDLKTVVVTRPASVGSSARVAVENEDQAHAMV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCEEEECCCCHHHHHH
RFVNGAQGVIEASRVACGRKMGLSYMITGTQGAISFTQERMAELKLYLHNDPVNRQGFRT
HHHCCCCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHEEEEEECCCCCCCCCEE
LLVGPAHPEYAAFCMAAGHGIGFNDQKTVEVRDLIDGIAMDTPLWPDFAEGWKVSRILDA
EEECCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHH
IALSHQDSRWVNVTDIV
HHHCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 9025289 [H]