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The map label for this gene is zraR [H]

Identifier: 170025129

GI number: 170025129

Start: 3201963

End: 3203327

Strand: Reverse

Name: zraR [H]

Synonym: YPK_2907

Alternate gene names: 170025129

Gene position: 3203327-3201963 (Counterclockwise)

Preceding gene: 170025130

Following gene: 170025128

Centisome position: 68.31

GC content: 44.76

Gene sequence:

>1365_bases
ATGACAACACATAAAGCGCATATTTTGGTCGTTGATGATGACCTGAGCCACTGCACAATTATCCAGGCTTTAATGAAAGG
CTGGGGTTATCAAACCACGCCAGCCCACAATGGATTAGAGGCCATCGAACTGGCTAAAGAGATCCCTTTCGATTTAATTC
TGACTGATGTGCGAATGTCTGAAATGGATGGTATTGAGGCATTAAAGGCAATTAAAGCCTATAACCCGGCAATCCCTATT
TTAATTATGACGGCTTATTCCAACGTTGAATCTGCGGTTGAGGCAATTAAAGCCGGGGCATACGATTATCTTACCAAACC
GCTTGATTTCGACATGTTACAACTCACCCTTGAGCGGGCACTGGAACATACGCATCTCAAGAATGAGAATAAAACACTTA
AACAGCAGATCATCAGTAACCAAAATATTATTGGTCGCAGCCCACAAATGCGCTATCTGATGGATATGGTTGGCATGATT
GCGCCTTCTGAAGCGACGGTGTTGATATGTGGAGAATCGGGTACGGGCAAAGAAATTATTGCCCGCTCAGTTCATGCTAA
CAGCTCCCGTAAAGATCAACCGTTGGTGATTGTTAACTGCGCGGCACTCAGTGAATCATTGCTGGAGTCCGAGCTATTCG
GCCATGAAAAAGGGGCGTTTACTGGCGCAGATAAACGTCGGGAAGGGCGCTTTATGGAGGCACATAAGGCAACGTTATTT
TTGGATGAGATTGGTGAAATCTCAGGGTTGATGCAGGCAAAACTCCTGCGTGCTATCCAAGAACGGGAGATCCAGCGCGT
TGGCAGTAATCAGACATTAGCTATTGATGTCAGGTTGATTGCCGCCACTAACCGCAATCTTAAAGCCGATGTTGATAGTG
GAAAGTTTCGCCAGGATCTCTACTATCGATTAAATGTGGTCACGATAGATACCCCGGCGTTGAGAGAGCGAAGCGAAGAT
ATTCCGCCGTTGTCGATGCATTTCTTGGAAAAGTTTGCGCTCAAGAACCGTAAATCAATCAAAGGATTCACACCGCAAGC
GATGAATATGCTGTTGAAATACAACTGGCCTGGTAACGTGCGTGAATTGGAAAATACGGTGGAGCGTGCGGTGATTTTAC
TGACCGGTGATTTCATCAGCGAGAAGGAGTTGCCGTTAAATATTAATCATTATATTCAGGAGAATGCCGGTAGTGAGAAT
ATAGGTTATGAGGATGCAGAAAAACCTATCCAGTCTCTCGAATGGGTCGAAATAGACGCTATTTTGACTGCGTTGGAAAA
GACGGGAGGCAATAAAACAGAGGCAGCAAAACATTTAGGCATCACGCGCAAAACATTGCAGGCAAAATTACAAAAAAGAA
ATTAG

Upstream 100 bases:

>100_bases
ACCAGCCACCCGCAATCTGGAACCCGCTTTGACATGACAATCCCCTTGGTACAACGCGGCCAATATCGCCCAGATGGGCA
AGAACAAAAGGCGTCGAATA

Downstream 100 bases:

>100_bases
CTATTTTTTTATAAAAATACAGGCATTTTAAAAAGCGGATTGTGTTTAAAATAAAAGTTTAAATATCAATGTGTTGTGTA
TTTACCTGCTTAATCTGACA

Product: two component, sigma54 specific, Fis family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 453

Protein sequence:

>454_residues
MTTHKAHILVVDDDLSHCTIIQALMKGWGYQTTPAHNGLEAIELAKEIPFDLILTDVRMSEMDGIEALKAIKAYNPAIPI
LIMTAYSNVESAVEAIKAGAYDYLTKPLDFDMLQLTLERALEHTHLKNENKTLKQQIISNQNIIGRSPQMRYLMDMVGMI
APSEATVLICGESGTGKEIIARSVHANSSRKDQPLVIVNCAALSESLLESELFGHEKGAFTGADKRREGRFMEAHKATLF
LDEIGEISGLMQAKLLRAIQEREIQRVGSNQTLAIDVRLIAATNRNLKADVDSGKFRQDLYYRLNVVTIDTPALRERSED
IPPLSMHFLEKFALKNRKSIKGFTPQAMNMLLKYNWPGNVRELENTVERAVILLTGDFISEKELPLNINHYIQENAGSEN
IGYEDAEKPIQSLEWVEIDAILTALEKTGGNKTEAAKHLGITRKTLQAKLQKRN

Sequences:

>Translated_454_residues
MTTHKAHILVVDDDLSHCTIIQALMKGWGYQTTPAHNGLEAIELAKEIPFDLILTDVRMSEMDGIEALKAIKAYNPAIPI
LIMTAYSNVESAVEAIKAGAYDYLTKPLDFDMLQLTLERALEHTHLKNENKTLKQQIISNQNIIGRSPQMRYLMDMVGMI
APSEATVLICGESGTGKEIIARSVHANSSRKDQPLVIVNCAALSESLLESELFGHEKGAFTGADKRREGRFMEAHKATLF
LDEIGEISGLMQAKLLRAIQEREIQRVGSNQTLAIDVRLIAATNRNLKADVDSGKFRQDLYYRLNVVTIDTPALRERSED
IPPLSMHFLEKFALKNRKSIKGFTPQAMNMLLKYNWPGNVRELENTVERAVILLTGDFISEKELPLNINHYIQENAGSEN
IGYEDAEKPIQSLEWVEIDAILTALEKTGGNKTEAAKHLGITRKTLQAKLQKRN
>Mature_453_residues
TTHKAHILVVDDDLSHCTIIQALMKGWGYQTTPAHNGLEAIELAKEIPFDLILTDVRMSEMDGIEALKAIKAYNPAIPIL
IMTAYSNVESAVEAIKAGAYDYLTKPLDFDMLQLTLERALEHTHLKNENKTLKQQIISNQNIIGRSPQMRYLMDMVGMIA
PSEATVLICGESGTGKEIIARSVHANSSRKDQPLVIVNCAALSESLLESELFGHEKGAFTGADKRREGRFMEAHKATLFL
DEIGEISGLMQAKLLRAIQEREIQRVGSNQTLAIDVRLIAATNRNLKADVDSGKFRQDLYYRLNVVTIDTPALRERSEDI
PPLSMHFLEKFALKNRKSIKGFTPQAMNMLLKYNWPGNVRELENTVERAVILLTGDFISEKELPLNINHYIQENAGSENI
GYEDAEKPIQSLEWVEIDAILTALEKTGGNKTEAAKHLGITRKTLQAKLQKRN

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=453, Percent_Identity=63.7969094922737, Blast_Score=595, Evalue=1e-171,
Organism=Escherichia coli, GI1788550, Length=448, Percent_Identity=46.6517857142857, Blast_Score=405, Evalue=1e-114,
Organism=Escherichia coli, GI1788905, Length=443, Percent_Identity=38.8261851015801, Blast_Score=331, Evalue=5e-92,
Organism=Escherichia coli, GI1790299, Length=462, Percent_Identity=39.8268398268398, Blast_Score=325, Evalue=4e-90,
Organism=Escherichia coli, GI87082117, Length=338, Percent_Identity=44.6745562130178, Blast_Score=278, Evalue=7e-76,
Organism=Escherichia coli, GI1789087, Length=339, Percent_Identity=44.2477876106195, Blast_Score=254, Evalue=6e-69,
Organism=Escherichia coli, GI1789233, Length=320, Percent_Identity=41.875, Blast_Score=239, Evalue=2e-64,
Organism=Escherichia coli, GI87082152, Length=236, Percent_Identity=50, Blast_Score=236, Evalue=2e-63,
Organism=Escherichia coli, GI1786524, Length=359, Percent_Identity=38.7186629526462, Blast_Score=234, Evalue=7e-63,
Organism=Escherichia coli, GI87081872, Length=326, Percent_Identity=41.1042944785276, Blast_Score=216, Evalue=3e-57,
Organism=Escherichia coli, GI1787583, Length=318, Percent_Identity=34.2767295597484, Blast_Score=193, Evalue=2e-50,
Organism=Escherichia coli, GI1789828, Length=259, Percent_Identity=37.4517374517375, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI87081858, Length=307, Percent_Identity=31.2703583061889, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1789149, Length=114, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1786784, Length=103, Percent_Identity=30.0970873786408, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788191, Length=129, Percent_Identity=30.2325581395349, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 50818; Mature: 50687

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTHKAHILVVDDDLSHCTIIQALMKGWGYQTTPAHNGLEAIELAKEIPFDLILTDVRMS
CCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCHHEEEEHHHHH
EMDGIEALKAIKAYNPAIPILIMTAYSNVESAVEAIKAGAYDYLTKPLDFDMLQLTLERA
HHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHH
LEHTHLKNENKTLKQQIISNQNIIGRSPQMRYLMDMVGMIAPSEATVLICGESGTGKEII
HHHHHCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHH
ARSVHANSSRKDQPLVIVNCAALSESLLESELFGHEKGAFTGADKRREGRFMEAHKATLF
HHHHCCCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCHHHHHHHHHH
LDEIGEISGLMQAKLLRAIQEREIQRVGSNQTLAIDVRLIAATNRNLKADVDSGKFRQDL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCCEECCCCCHHHHEE
YYRLNVVTIDTPALRERSEDIPPLSMHFLEKFALKNRKSIKGFTPQAMNMLLKYNWPGNV
EEEEEEEEECCHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHEEECCCCCH
RELENTVERAVILLTGDFISEKELPLNINHYIQENAGSENIGYEDAEKPIQSLEWVEIDA
HHHHHHHHHEEEEEECCCCCCCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHCCHHHHHH
ILTALEKTGGNKTEAAKHLGITRKTLQAKLQKRN
HHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHCCC
>Mature Secondary Structure 
TTHKAHILVVDDDLSHCTIIQALMKGWGYQTTPAHNGLEAIELAKEIPFDLILTDVRMS
CCCEEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCHHEEEEHHHHH
EMDGIEALKAIKAYNPAIPILIMTAYSNVESAVEAIKAGAYDYLTKPLDFDMLQLTLERA
HHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHH
LEHTHLKNENKTLKQQIISNQNIIGRSPQMRYLMDMVGMIAPSEATVLICGESGTGKEII
HHHHHCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHH
ARSVHANSSRKDQPLVIVNCAALSESLLESELFGHEKGAFTGADKRREGRFMEAHKATLF
HHHHCCCCCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCHHHHHHHHHH
LDEIGEISGLMQAKLLRAIQEREIQRVGSNQTLAIDVRLIAATNRNLKADVDSGKFRQDL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCCEECCCCCHHHHEE
YYRLNVVTIDTPALRERSEDIPPLSMHFLEKFALKNRKSIKGFTPQAMNMLLKYNWPGNV
EEEEEEEEECCHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHEEECCCCCH
RELENTVERAVILLTGDFISEKELPLNINHYIQENAGSENIGYEDAEKPIQSLEWVEIDA
HHHHHHHHHEEEEEECCCCCCCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHCCHHHHHH
ILTALEKTGGNKTEAAKHLGITRKTLQAKLQKRN
HHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11243806 [H]