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The map label for this gene is deoC1

Identifier: 170024962

GI number: 170024962

Start: 3017883

End: 3018554

Strand: Direct

Name: deoC1

Synonym: YPK_2737

Alternate gene names: 170024962

Gene position: 3017883-3018554 (Clockwise)

Preceding gene: 170024961

Following gene: 170024963

Centisome position: 64.35

GC content: 48.07

Gene sequence:

>672_bases
ATGACTACCAATTACGCTCATTATATTGATCACACTCTACTGGCGATGGATGCCACCGAAGCGCAAATCATTAAACTGTG
CGAAGAAGCTAAACAACACCATTTCTATGCTGTATGTGTTAACTCTGGATACGTTCCTGTGGCTGCCCAGCAATTAGCCG
GGAGTTCAGTCAAAGTCTGCTCAGTCATTGGTTTCCCGCTGGGTGCAGGTCTGACTGCAGCAAAAGCTTTTGAAGCTCAA
GCCGCGATCAATGCAGGTGCACAAGAGATTGATATGGTTATCAATGTTGGCTGGCTGAAAAGTGGCAAAATTGCCGACGT
CAAAGCGGATATTAAGGCCGTGCGGGACAATTGCGCCGCTACACCGTTGAAGGTAATATTAGAAACTTGCCTGCTCAGCG
ATGAACAAATTGTACAAGTTTGCGAAATGTGTCGTGAACTTGACGTTGCTTTTGTTAAAACATCAACCGGTTTTAGTACC
GGTGGCGCTAAAGAAGAACACGTCAAATTGATGCGTGCAACGGTTGGCCCGGTTATGGGGGTTAAAGCCTCTGGTGCTGT
TCGTGACAGAGCAACCGCCGAAACCATGATCCAGGCAGGTGCTACGCGAATTGGTACCAGCTCTGGAGTTGCCATTGTTT
CAGGTCAACAAGCCGCCGCATCAGGTTACTAG

Upstream 100 bases:

>100_bases
TTTAAATAACAAAATTCATGAATTCACGGTGTGTCGCTCCTTTTTACTCATCAAAATGTTATGATTATCACAATTACCAA
TAAGCTCAAGGATCCTAATC

Downstream 100 bases:

>100_bases
AATGTACTGACCGTGGTTGAAAAATCTATAAGCGTGATTGAAAAATATATAAAAGATTGACCGCACCTTGGGCTGCTCCG
GTGGTTTACGTCACGACGCC

Product: deoxyribose-phosphate aldolase

Products: NA

Alternate protein names: Phosphodeoxyriboaldolase 1; DERA 1; Deoxyriboaldolase 1

Number of amino acids: Translated: 223; Mature: 222

Protein sequence:

>223_residues
MTTNYAHYIDHTLLAMDATEAQIIKLCEEAKQHHFYAVCVNSGYVPVAAQQLAGSSVKVCSVIGFPLGAGLTAAKAFEAQ
AAINAGAQEIDMVINVGWLKSGKIADVKADIKAVRDNCAATPLKVILETCLLSDEQIVQVCEMCRELDVAFVKTSTGFST
GGAKEEHVKLMRATVGPVMGVKASGAVRDRATAETMIQAGATRIGTSSGVAIVSGQQAAASGY

Sequences:

>Translated_223_residues
MTTNYAHYIDHTLLAMDATEAQIIKLCEEAKQHHFYAVCVNSGYVPVAAQQLAGSSVKVCSVIGFPLGAGLTAAKAFEAQ
AAINAGAQEIDMVINVGWLKSGKIADVKADIKAVRDNCAATPLKVILETCLLSDEQIVQVCEMCRELDVAFVKTSTGFST
GGAKEEHVKLMRATVGPVMGVKASGAVRDRATAETMIQAGATRIGTSSGVAIVSGQQAAASGY
>Mature_222_residues
TTNYAHYIDHTLLAMDATEAQIIKLCEEAKQHHFYAVCVNSGYVPVAAQQLAGSSVKVCSVIGFPLGAGLTAAKAFEAQA
AINAGAQEIDMVINVGWLKSGKIADVKADIKAVRDNCAATPLKVILETCLLSDEQIVQVCEMCRELDVAFVKTSTGFSTG
GAKEEHVKLMRATVGPVMGVKASGAVRDRATAETMIQAGATRIGTSSGVAIVSGQQAAASGY

Specific function: Nucleotide and deoxyribonucleotide catabolism. [C]

COG id: COG0274

COG function: function code F; Deoxyribose-phosphate aldolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the deoC/fbaB aldolase family. DeoC type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790841, Length=194, Percent_Identity=29.3814432989691, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DEOC1_YERPE (Q8ZGH4)

Other databases:

- EMBL:   AL590842
- EMBL:   AE009952
- EMBL:   AE017042
- PIR:   AF0161
- RefSeq:   NP_670160.1
- RefSeq:   NP_992635.1
- RefSeq:   YP_002346348.1
- ProteinModelPortal:   Q8ZGH4
- SMR:   Q8ZGH4
- IntAct:   Q8ZGH4
- GeneID:   1147807
- GeneID:   1174165
- GeneID:   2764428
- GenomeReviews:   AE009952_GR
- GenomeReviews:   AE017042_GR
- GenomeReviews:   AL590842_GR
- KEGG:   ype:YPO1323
- KEGG:   ypk:y2860
- KEGG:   ypm:YP_1269
- HOGENOM:   HBG636421
- OMA:   GANTPEV
- ProtClustDB:   PRK00507
- BioCyc:   YPES187410:Y2860-MONOMER
- BioCyc:   YPES214092:YPO1323-MONOMER
- BRENDA:   4.1.2.4
- GO:   GO:0005737
- HAMAP:   MF_00114
- InterPro:   IPR013785
- InterPro:   IPR011343
- InterPro:   IPR002915
- InterPro:   IPR022979
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR10889
- PIRSF:   PIRSF001357
- TIGRFAMs:   TIGR00126

Pfam domain/function: PF01791 DeoC

EC number: =4.1.2.4

Molecular weight: Translated: 23266; Mature: 23135

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: NA

Important sites: ACT_SITE 153-153 ACT_SITE 182-182

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTNYAHYIDHTLLAMDATEAQIIKLCEEAKQHHFYAVCVNSGYVPVAAQQLAGSSVKVC
CCCCHHHHHHHHHHEECCHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHCCCCEEEH
SVIGFPLGAGLTAAKAFEAQAAINAGAQEIDMVINVGWLKSGKIADVKADIKAVRDNCAA
HHCCCCCCCCCHHHHHHHHHHHHHCCHHHEEEEEEECCCCCCCEEHHHHHHHHHHHCCCC
TPLKVILETCLLSDEQIVQVCEMCRELDVAFVKTSTGFSTGGAKEEHVKLMRATVGPVMG
CHHHHHHHHHHCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHCHHHC
VKASGAVRDRATAETMIQAGATRIGTSSGVAIVSGQQAAASGY
CCCCCCHHHHHHHHHHHHHCCHHCCCCCCEEEEECCCHHCCCC
>Mature Secondary Structure 
TTNYAHYIDHTLLAMDATEAQIIKLCEEAKQHHFYAVCVNSGYVPVAAQQLAGSSVKVC
CCCHHHHHHHHHHEECCHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHCCCCEEEH
SVIGFPLGAGLTAAKAFEAQAAINAGAQEIDMVINVGWLKSGKIADVKADIKAVRDNCAA
HHCCCCCCCCCHHHHHHHHHHHHHCCHHHEEEEEEECCCCCCCEEHHHHHHHHHHHCCCC
TPLKVILETCLLSDEQIVQVCEMCRELDVAFVKTSTGFSTGGAKEEHVKLMRATVGPVMG
CHHHHHHHHHHCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHCHHHC
VKASGAVRDRATAETMIQAGATRIGTSSGVAIVSGQQAAASGY
CCCCCCHHHHHHHHHHHHHCCHHCCCCCCEEEEECCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430