Click here to switch to the map view.

The map label for this gene is dcyD [H]

Identifier: 170024602

GI number: 170024602

Start: 2611600

End: 2612619

Strand: Reverse

Name: dcyD [H]

Synonym: YPK_2377

Alternate gene names: 170024602

Gene position: 2612619-2611600 (Counterclockwise)

Preceding gene: 170024603

Following gene: 170024601

Centisome position: 55.71

GC content: 51.37

Gene sequence:

>1020_bases
ATGATTCATCAATTCCTTGGGGGGCACGTGACGCTTCAACACAAACTGACGCAATTCCCGCGTCTCGATCTGGTCGGTAA
TGCGACGCCATTAGAAAAGCTGTCTCGTCTATCTGATTATCTGGGACGTGAAATTTACATTAAACGTGATGATGTCACGC
CTGTGGCGCTTGGCGGGAATAAACTGCGCAAGCTAGAATTCTTAGCCGCAGATGCCTTGAGACAGGGAGCCGATACGCTG
GTTACGGCTGGTGCTATTCAATCTAATCATGTCCGCCAAACCGCCGCCGTGGCCGCGAAACTGGGGCTGCATTGCGTTGC
GCTGTTGGAAAACCCCATTGGTACTGAGCAGGCAAACTATCTGACCAATGGGAACCGGCTGTTACTGGACCTATTCAATG
TTGATGTTGTGATGTGTGAGGCATTGAACGATCCAAATCAGCAATTAGCAGAATTGGCTACCCGCGTGGAAGCGCAGGGT
TTCCGCCCATATGTGGTACCGATTGGCGGTTCTAATGCCTTGGGCGCGCTGGGTTATGTGCAGTGCTCACTGGAAATTGC
TGCTCAAGCCGCGGGCAATGTTGCGTTTAGTTCGGTCGTCGTGGCCTCTGGCAGTGCGGGAACACATGCAGGATTGGCGG
TTGGTCTACAGCAGTTGTTACCCGATGCGGAATTAATCGGTGTGACGGTATCACGTAGTGCCGATGAACAGCGGCCTAAA
GTGGCACAGATTCAACAAGCGTTGGCGACATCATTAGGGATGACGGACCCATTGGCAAAAATCACCTTGTGGGATAGTTA
TTTTGCCCCGCAATATGGGATGCCAAACGAAGAGGGGATAGCGGCTATTAAGCTCTTGGCAAGACTGGAAGGAATATTGT
TGGACCCTGTGTATACCGGTAAGGCGATGGCGGGCTTACTTGATGGTATTGAACAGCAAAAATTCTGCGACAAAGGGCCA
ATTTTATTTATCCACACTGGCGGGGCACCTGCGCTGTTTGCTTATCATCCGCAGGTGTAG

Upstream 100 bases:

>100_bases
AGTTATTCCCATTAAGCTATCCCCTGCGATATTGGTCACTGACATCACTCATAAAATCAGTGCTTATTAATGTCACATCT
GATAAATCTATATAAAAGCC

Downstream 100 bases:

>100_bases
CCTAAGCTTTCATTATTACTTATTCCATTTTTAACTATATTTATCATTTTATATTTCTTCACTTCATTAATAGCACTGGT
AAAGTGTTGAATATCAAAAA

Product: D-cysteine desulfhydrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MIHQFLGGHVTLQHKLTQFPRLDLVGNATPLEKLSRLSDYLGREIYIKRDDVTPVALGGNKLRKLEFLAADALRQGADTL
VTAGAIQSNHVRQTAAVAAKLGLHCVALLENPIGTEQANYLTNGNRLLLDLFNVDVVMCEALNDPNQQLAELATRVEAQG
FRPYVVPIGGSNALGALGYVQCSLEIAAQAAGNVAFSSVVVASGSAGTHAGLAVGLQQLLPDAELIGVTVSRSADEQRPK
VAQIQQALATSLGMTDPLAKITLWDSYFAPQYGMPNEEGIAAIKLLARLEGILLDPVYTGKAMAGLLDGIEQQKFCDKGP
ILFIHTGGAPALFAYHPQV

Sequences:

>Translated_339_residues
MIHQFLGGHVTLQHKLTQFPRLDLVGNATPLEKLSRLSDYLGREIYIKRDDVTPVALGGNKLRKLEFLAADALRQGADTL
VTAGAIQSNHVRQTAAVAAKLGLHCVALLENPIGTEQANYLTNGNRLLLDLFNVDVVMCEALNDPNQQLAELATRVEAQG
FRPYVVPIGGSNALGALGYVQCSLEIAAQAAGNVAFSSVVVASGSAGTHAGLAVGLQQLLPDAELIGVTVSRSADEQRPK
VAQIQQALATSLGMTDPLAKITLWDSYFAPQYGMPNEEGIAAIKLLARLEGILLDPVYTGKAMAGLLDGIEQQKFCDKGP
ILFIHTGGAPALFAYHPQV
>Mature_339_residues
MIHQFLGGHVTLQHKLTQFPRLDLVGNATPLEKLSRLSDYLGREIYIKRDDVTPVALGGNKLRKLEFLAADALRQGADTL
VTAGAIQSNHVRQTAAVAAKLGLHCVALLENPIGTEQANYLTNGNRLLLDLFNVDVVMCEALNDPNQQLAELATRVEAQG
FRPYVVPIGGSNALGALGYVQCSLEIAAQAAGNVAFSSVVVASGSAGTHAGLAVGLQQLLPDAELIGVTVSRSADEQRPK
VAQIQQALATSLGMTDPLAKITLWDSYFAPQYGMPNEEGIAAIKLLARLEGILLDPVYTGKAMAGLLDGIEQQKFCDKGP
ILFIHTGGAPALFAYHPQV

Specific function: Catalyzes the alpha,beta-elimination reaction of D- cysteine and of several D-cysteine derivatives. It could be a defense mechanism against D-cysteine [H]

COG id: COG2515

COG function: function code E; 1-aminocyclopropane-1-carboxylate deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ACC deaminase/D-cysteine desulfhydrase family [H]

Homologues:

Organism=Escherichia coli, GI87082000, Length=326, Percent_Identity=77.6073619631902, Blast_Score=521, Evalue=1e-149,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005966
- InterPro:   IPR001926 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.4.1.15 [H]

Molecular weight: Translated: 36038; Mature: 36038

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIHQFLGGHVTLQHKLTQFPRLDLVGNATPLEKLSRLSDYLGREIYIKRDDVTPVALGGN
CCCCCCCCCEEEEEHHHHCCCEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCEEEECCC
KLRKLEFLAADALRQGADTLVTAGAIQSNHVRQTAAVAAKLGLHCVALLENPIGTEQANY
HHHHHHHHHHHHHHCCCHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCE
LTNGNRLLLDLFNVDVVMCEALNDPNQQLAELATRVEAQGFRPYVVPIGGSNALGALGYV
EECCCEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEE
QCSLEIAAQAAGNVAFSSVVVASGSAGTHAGLAVGLQQLLPDAELIGVTVSRSADEQRPK
EEHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCH
VAQIQQALATSLGMTDPLAKITLWDSYFAPQYGMPNEEGIAAIKLLARLEGILLDPVYTG
HHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCEEECCCCCC
KAMAGLLDGIEQQKFCDKGPILFIHTGGAPALFAYHPQV
HHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEECCCC
>Mature Secondary Structure
MIHQFLGGHVTLQHKLTQFPRLDLVGNATPLEKLSRLSDYLGREIYIKRDDVTPVALGGN
CCCCCCCCCEEEEEHHHHCCCEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCEEEECCC
KLRKLEFLAADALRQGADTLVTAGAIQSNHVRQTAAVAAKLGLHCVALLENPIGTEQANY
HHHHHHHHHHHHHHCCCHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCE
LTNGNRLLLDLFNVDVVMCEALNDPNQQLAELATRVEAQGFRPYVVPIGGSNALGALGYV
EECCCEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEE
QCSLEIAAQAAGNVAFSSVVVASGSAGTHAGLAVGLQQLLPDAELIGVTVSRSADEQRPK
EEHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCH
VAQIQQALATSLGMTDPLAKITLWDSYFAPQYGMPNEEGIAAIKLLARLEGILLDPVYTG
HHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCEEECCCCCC
KAMAGLLDGIEQQKFCDKGPILFIHTGGAPALFAYHPQV
HHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]