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The map label for this gene is cmoA2

Identifier: 170024385

GI number: 170024385

Start: 2382419

End: 2383222

Strand: Direct

Name: cmoA2

Synonym: YPK_2151

Alternate gene names: 170024385

Gene position: 2382419-2383222 (Clockwise)

Preceding gene: 170024384

Following gene: 170024386

Centisome position: 50.8

GC content: 49.13

Gene sequence:

>804_bases
ATGCCAAACCGCGATACTCAATCTCAAAACGATACGCCACGTCATTCTCCAGAGGCGGCAGAACCCCAGCGCGATAGCCT
GTTTGCTGCGCCTATTGCTAAATTAGGTGACTGGACCTTTGACGAGAAAGTCGCTGAAGTGTTCCCCGATATGATCCAGC
GCTCGGTTCCCGGCTATTCAAATATTATTTCGATGATAGGCATGCTGGCAGAGCGTTTTGTGCAACCGAACAGCCAAATT
TATGACCTTGGTTGTTCGCTGGGTGCCGCCACGCTGTCAATGCGCCGTAATATTAAGGCCGAAGGCTGCAAAATTATCGC
AGTGGATAACTCACCCGCGATGGTTGAACGTTGCCGTCGCCATATTGATGCTTTCCGGGCAGAGACGCCGGTAGACGTGG
TTGAAGCCGATATTTTGGATATCAAACTGGAAAACGCATCGATGGTGGTGTTGAACTTCACCTTGCAATTTCTCGAACCT
GCCAATCGCCAGCGCCTACTCAATCAGGTATATCAAGGGCTGCGCCCAGGTGGCGCACTCGTATTGTCAGAAAAATTCAG
TTTTGCCGATCATAACGTAGGCGAATTATTGTTCAATATGCACCACGATTTTAAACGCGCCAATGGTTACAGTGAGCTGG
AAATCAGCCAAAAACGCAGCATGTTGGAAAATGTCATGCTGACCGATTCCGTGGAAACCCACAAAAATCGTCTGCATCAG
GCGGGGTTTGAACACGCGGAAGTCTGGTTCCAATGCTTTAATTTTGGTTCACTGATTGCCCTGAAAGCAGGAGAGGCTCA
ATGA

Upstream 100 bases:

>100_bases
CCCTCTCGCGCCCTCGCTTTATCACGCTTATCGGCCAAGTTTTCTGTTATAATATGCGCCTTTAATTTCTTGCTTTGTTT
ATCTCAGAATCTCAGACGCC

Downstream 100 bases:

>100_bases
TTGAATTTGGCGATTTTTATCGGCTGATTGCCAAAGGCCCATTAAGCCCATGGTTAGATACTCTGCCCGCACAGCTCAGC
GCCTGGCAGCGCGAATCGTT

Product: methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MPNRDTQSQNDTPRHSPEAAEPQRDSLFAAPIAKLGDWTFDEKVAEVFPDMIQRSVPGYSNIISMIGMLAERFVQPNSQI
YDLGCSLGAATLSMRRNIKAEGCKIIAVDNSPAMVERCRRHIDAFRAETPVDVVEADILDIKLENASMVVLNFTLQFLEP
ANRQRLLNQVYQGLRPGGALVLSEKFSFADHNVGELLFNMHHDFKRANGYSELEISQKRSMLENVMLTDSVETHKNRLHQ
AGFEHAEVWFQCFNFGSLIALKAGEAQ

Sequences:

>Translated_267_residues
MPNRDTQSQNDTPRHSPEAAEPQRDSLFAAPIAKLGDWTFDEKVAEVFPDMIQRSVPGYSNIISMIGMLAERFVQPNSQI
YDLGCSLGAATLSMRRNIKAEGCKIIAVDNSPAMVERCRRHIDAFRAETPVDVVEADILDIKLENASMVVLNFTLQFLEP
ANRQRLLNQVYQGLRPGGALVLSEKFSFADHNVGELLFNMHHDFKRANGYSELEISQKRSMLENVMLTDSVETHKNRLHQ
AGFEHAEVWFQCFNFGSLIALKAGEAQ
>Mature_266_residues
PNRDTQSQNDTPRHSPEAAEPQRDSLFAAPIAKLGDWTFDEKVAEVFPDMIQRSVPGYSNIISMIGMLAERFVQPNSQIY
DLGCSLGAATLSMRRNIKAEGCKIIAVDNSPAMVERCRRHIDAFRAETPVDVVEADILDIKLENASMVVLNFTLQFLEPA
NRQRLLNQVYQGLRPGGALVLSEKFSFADHNVGELLFNMHHDFKRANGYSELEISQKRSMLENVMLTDSVETHKNRLHQA
GFEHAEVWFQCFNFGSLIALKAGEAQ

Specific function: Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U)

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. CmoA family

Homologues:

Organism=Escherichia coli, GI1788177, Length=244, Percent_Identity=83.6065573770492, Blast_Score=441, Evalue=1e-125,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CMOA2_YERPB (B2K316)

Other databases:

- EMBL:   CP001048
- RefSeq:   YP_001872512.1
- ProteinModelPortal:   B2K316
- SMR:   B2K316
- GeneID:   6259449
- GenomeReviews:   CP001048_GR
- KEGG:   ypb:YPTS_2092
- HOGENOM:   HBG296860
- OMA:   YSELEVS
- ProtClustDB:   CLSK2519555
- HAMAP:   MF_01589
- InterPro:   IPR013216
- InterPro:   IPR005271
- PIRSF:   PIRSF006325
- TIGRFAMs:   TIGR00740

Pfam domain/function: PF08241 Methyltransf_11

EC number: NA

Molecular weight: Translated: 30040; Mature: 29909

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: NA

Important sites: BINDING 59-59 BINDING 109-109 BINDING 152-152 BINDING 219-219

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNRDTQSQNDTPRHSPEAAEPQRDSLFAAPIAKLGDWTFDEKVAEVFPDMIQRSVPGYS
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHH
NIISMIGMLAERFVQPNSQIYDLGCSLGAATLSMRRNIKAEGCKIIAVDNSPAMVERCRR
HHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHH
HIDAFRAETPVDVVEADILDIKLENASMVVLNFTLQFLEPANRQRLLNQVYQGLRPGGAL
HHHHHHCCCCHHHHHHHHEEEEECCCCEEEEEHHHHHHCCCCHHHHHHHHHHCCCCCCEE
VLSEKFSFADHNVGELLFNMHHDFKRANGYSELEISQKRSMLENVMLTDSVETHKNRLHQ
EEECCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
AGFEHAEVWFQCFNFGSLIALKAGEAQ
CCCHHHHHHHHHHCCCCEEEEECCCCC
>Mature Secondary Structure 
PNRDTQSQNDTPRHSPEAAEPQRDSLFAAPIAKLGDWTFDEKVAEVFPDMIQRSVPGYS
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHH
NIISMIGMLAERFVQPNSQIYDLGCSLGAATLSMRRNIKAEGCKIIAVDNSPAMVERCRR
HHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHH
HIDAFRAETPVDVVEADILDIKLENASMVVLNFTLQFLEPANRQRLLNQVYQGLRPGGAL
HHHHHHCCCCHHHHHHHHEEEEECCCCEEEEEHHHHHHCCCCHHHHHHHHHHCCCCCCEE
VLSEKFSFADHNVGELLFNMHHDFKRANGYSELEISQKRSMLENVMLTDSVETHKNRLHQ
EEECCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
AGFEHAEVWFQCFNFGSLIALKAGEAQ
CCCHHHHHHHHHHCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA