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The map label for this gene is yeaD [H]

Identifier: 170024331

GI number: 170024331

Start: 2326327

End: 2327202

Strand: Direct

Name: yeaD [H]

Synonym: YPK_2097

Alternate gene names: 170024331

Gene position: 2326327-2327202 (Clockwise)

Preceding gene: 170024330

Following gene: 170024334

Centisome position: 49.61

GC content: 48.17

Gene sequence:

>876_bases
ATGAACGAGAAAGTATTTACTCTCCCTGTTGTTGAACAAATTTCTCCTTATATCAGCCAGCGTCAACTGGATGAATTGCC
GGTAGTGGTTGTTTCTCATCCTAAGGTGCGTGCGGCAATAAGTTTGCAGGGGGCCCACTTACTGGCCTATCAACCCAGTG
GTGAGCAACCCATTATCTGGCTGAGCAATAACACGCCTTTTAAAGAAGGTATTGCGATTCGTGGAGGGGTTCCAATTTGT
TGGCCTTGGTTTGGCCCAACCGCACAACCTGCCCATGGTTTTGCCCGCATCTTGCCATGGACGCTCAGTGCTCATGATGA
AAATGAAAACGGCGTCATTCTGACTTTCACCCTTGAAGACAACGACATGACCCGCCAATACTGGCCACATGCCTTCACCC
TGATCGCCCGTTTCAAGTTGGGAGATGAATGTGAAGTTGAACTGGAATCACACGGTGATTATCAGGCTGCTGCGGCATTA
CATACCTACTTCCAGATTGGCGATATAAGCCAAATTAAAGTCAGCGGGCTGGGTGAGAAATATTTAGATAAAGTGCTGAA
AGTTGCCGATGTCACTCAACAAGGCGATTTAGTCTTTAACGGCCAAACTGACCGTGTCTATACCCAACCTGAAGCCTATA
GTCTGATAAAAGATGCCGCGCTGAAACGAACTATTGAGGTCCATCACCATCACCAAAGTGATGTGGTTGCCTGGAACCCC
GGCGCTGAATTGTCCTGCAGCATGGTAGATATGCCAAATGATGGCTATAAAACGATGGTTTGCGTAGAAACCGCACGAGT
CAACAAGCCATTGGTGGCTGCGCCTGATGCACCAGCACGTTTGGCGATGACCATCCGTAGTCGTAAAAACACCTAA

Upstream 100 bases:

>100_bases
CACCTGCATCGCACGCTTGCTGCAAGATTCAATGCCTGTGATATTATCGAAAGACTGAAGCTCAACTGAATCCAGTTCCT
TTTCCCATAAGGCCAAACGA

Downstream 100 bases:

>100_bases
TCCCGGCAGTCCGGTCAATATAAAAATGGGGCCTTTGGCCCCATGGTCTTGCTCATAGCAACTCAACGCTGATTAGCGGA
ATGTATAGGTAACGCCTGTC

Product: aldose 1-epimerase

Products: NA

Alternate protein names: Putative D-hexose-6-phosphate mutarotase; Unknown protein from 2D-page spots T26/PR37 [H]

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MNEKVFTLPVVEQISPYISQRQLDELPVVVVSHPKVRAAISLQGAHLLAYQPSGEQPIIWLSNNTPFKEGIAIRGGVPIC
WPWFGPTAQPAHGFARILPWTLSAHDENENGVILTFTLEDNDMTRQYWPHAFTLIARFKLGDECEVELESHGDYQAAAAL
HTYFQIGDISQIKVSGLGEKYLDKVLKVADVTQQGDLVFNGQTDRVYTQPEAYSLIKDAALKRTIEVHHHHQSDVVAWNP
GAELSCSMVDMPNDGYKTMVCVETARVNKPLVAAPDAPARLAMTIRSRKNT

Sequences:

>Translated_291_residues
MNEKVFTLPVVEQISPYISQRQLDELPVVVVSHPKVRAAISLQGAHLLAYQPSGEQPIIWLSNNTPFKEGIAIRGGVPIC
WPWFGPTAQPAHGFARILPWTLSAHDENENGVILTFTLEDNDMTRQYWPHAFTLIARFKLGDECEVELESHGDYQAAAAL
HTYFQIGDISQIKVSGLGEKYLDKVLKVADVTQQGDLVFNGQTDRVYTQPEAYSLIKDAALKRTIEVHHHHQSDVVAWNP
GAELSCSMVDMPNDGYKTMVCVETARVNKPLVAAPDAPARLAMTIRSRKNT
>Mature_291_residues
MNEKVFTLPVVEQISPYISQRQLDELPVVVVSHPKVRAAISLQGAHLLAYQPSGEQPIIWLSNNTPFKEGIAIRGGVPIC
WPWFGPTAQPAHGFARILPWTLSAHDENENGVILTFTLEDNDMTRQYWPHAFTLIARFKLGDECEVELESHGDYQAAAAL
HTYFQIGDISQIKVSGLGEKYLDKVLKVADVTQQGDLVFNGQTDRVYTQPEAYSLIKDAALKRTIEVHHHHQSDVVAWNP
GAELSCSMVDMPNDGYKTMVCVETARVNKPLVAAPDAPARLAMTIRSRKNT

Specific function: Unknown

COG id: COG0676

COG function: function code G; Uncharacterized enzymes related to aldose 1-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Glucose-6-phosphate 1-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI87081973, Length=293, Percent_Identity=55.6313993174061, Blast_Score=358, Evalue=1e-100,
Organism=Saccharomyces cerevisiae, GI6323746, Length=271, Percent_Identity=29.520295202952, Blast_Score=100, Evalue=3e-22,
Organism=Drosophila melanogaster, GI19921284, Length=253, Percent_Identity=32.8063241106719, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI28574481, Length=168, Percent_Identity=31.547619047619, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008183
- InterPro:   IPR011013
- InterPro:   IPR014718 [H]

Pfam domain/function: PF01263 Aldose_epim [H]

EC number: =5.1.3.15 [H]

Molecular weight: Translated: 32396; Mature: 32396

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEKVFTLPVVEQISPYISQRQLDELPVVVVSHPKVRAAISLQGAHLLAYQPSGEQPIIW
CCCCEEEEHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEEECCCEEEEECCCCCCCEEE
LSNNTPFKEGIAIRGGVPICWPWFGPTAQPAHGFARILPWTLSAHDENENGVILTFTLED
EECCCCHHHCEEEECCCCEEECCCCCCCCCCCCHHHHCCEEEECCCCCCCCEEEEEEECC
NDMTRQYWPHAFTLIARFKLGDECEVELESHGDYQAAAALHTYFQIGDISQIKVSGLGEK
CCCCHHHCCHHEEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHEECCCCEEEEECCCHH
YLDKVLKVADVTQQGDLVFNGQTDRVYTQPEAYSLIKDAALKRTIEVHHHHQSDVVAWNP
HHHHHHHHHCCCCCCCEEECCCCCEEEECCHHHHHHHHHHHHHHHEEEECCCCCEEEECC
GAELSCSMVDMPNDGYKTMVCVETARVNKPLVAAPDAPARLAMTIRSRKNT
CCCEEEEEEECCCCCCEEEEEEEEHHCCCCEEECCCCCCEEEEEEECCCCC
>Mature Secondary Structure
MNEKVFTLPVVEQISPYISQRQLDELPVVVVSHPKVRAAISLQGAHLLAYQPSGEQPIIW
CCCCEEEEHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEEECCCEEEEECCCCCCCEEE
LSNNTPFKEGIAIRGGVPICWPWFGPTAQPAHGFARILPWTLSAHDENENGVILTFTLED
EECCCCHHHCEEEECCCCEEECCCCCCCCCCCCHHHHCCEEEECCCCCCCCEEEEEEECC
NDMTRQYWPHAFTLIARFKLGDECEVELESHGDYQAAAALHTYFQIGDISQIKVSGLGEK
CCCCHHHCCHHEEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHEECCCCEEEEECCCHH
YLDKVLKVADVTQQGDLVFNGQTDRVYTQPEAYSLIKDAALKRTIEVHHHHQSDVVAWNP
HHHHHHHHHCCCCCCCEEECCCCCEEEECCHHHHHHHHHHHHHHHEEEECCCCCEEEECC
GAELSCSMVDMPNDGYKTMVCVETARVNKPLVAAPDAPARLAMTIRSRKNT
CCCEEEEEEECCCCCCEEEEEEEEHHCCCCEEECCCCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 9298646; 10493123 [H]