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The map label for this gene is tus [H]

Identifier: 170024221

GI number: 170024221

Start: 2204936

End: 2205910

Strand: Direct

Name: tus [H]

Synonym: YPK_1984

Alternate gene names: 170024221

Gene position: 2204936-2205910 (Clockwise)

Preceding gene: 170024220

Following gene: 170024223

Centisome position: 47.02

GC content: 43.28

Gene sequence:

>975_bases
ATGTATGTTGTAACTAAGCCGCCTTATTTAGAAAAGAATATGAACAAGTATGATTTGATAGAACGAATGAATACTCGCTT
TGCTGAGTTAGAAGTAACACTTCATCAACTCCACCAGCAATTGGACGATTTACCTCTAATTGCTGCCAGAGTATTTTCTC
TCCCTGAAATAGAAAAAGGCACTGAGCATCAACCCATTGAGCAAATTACCGTCAATATAACCGAGGGTGAACACGCCAAA
AGGTTGGGGTTACAACATTTCCAACGATTATTTCTTCATCACCAAGGGCAGCATGTTAGCAGTAAAGCAGCACTACGCTT
ACCTGGCGTACTCTGCTTCTCCGTGACCGACAAAGAACTCATTGAATGCCAAGATATAATAAAAAAAACCAATCAGTTAA
AAGCTGAGTTAGAACATATTATTACTGTGGAATCAGGCTTACCCAGCGAACAACGCTTTGAATTTGTTCACACACACTTA
CATGGCCTGATAACCCTGAATACCTACCGCACCATTACCCCATTAATCAACCCCAGTTCAGTGCGCTTTGGCTGGGCCAA
CAAACACATTATTAAAAATGTGACTCGCGAAGATATATTGCTACAGCTAGAAAAAAGCCTGAATGCTGGCCGAGCTGTTC
CTCCATTTACACGTGAGCAATGGAGGGAACTGATTAGCTTGGAAATAAATGATGTGCAGCGTTTGCCAGAAAAGACACGG
CTGAAAATTAAAAGGCCCGTAAAAGTGCAGCCCATCGCAAGAGTATGGTATCAAGAACAACAAAAACAGGTACAACACCC
CTGCCCCATGCCCCTGATTGCGTTCTGTCAGCGTCAGTCAGGGGCCGAGCTACCGAAATTAGGCGAGTTGACCGATTATG
ATGTGAAGCATATCAAGCATAAATATAAGCCAGATGCGAAACCGCTACGTTTGCTGGTACCGCGCTTGCATCTTTATGTC
GAACTGGAACCGTAA

Upstream 100 bases:

>100_bases
GAATTCTCACGTTTTAAGCGCCCTTTTCTGTTTTATATGTCCTTTTGAATCTAATGACATTTATGTATCTACATGTGGCT
ATCTTTAGGAGAATAAGACA

Downstream 100 bases:

>100_bases
AGAATACCATTTATTGCGGCTTAGCCACTGTGAAAACGCCGGTAATCCACCCCGGCGTTAATATAACAATGTTTATCCGC
TATTTCTTCATACTGCCGAC

Product: DNA replication terminus site-binding protein

Products: NA

Alternate protein names: Ter-binding protein [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MYVVTKPPYLEKNMNKYDLIERMNTRFAELEVTLHQLHQQLDDLPLIAARVFSLPEIEKGTEHQPIEQITVNITEGEHAK
RLGLQHFQRLFLHHQGQHVSSKAALRLPGVLCFSVTDKELIECQDIIKKTNQLKAELEHIITVESGLPSEQRFEFVHTHL
HGLITLNTYRTITPLINPSSVRFGWANKHIIKNVTREDILLQLEKSLNAGRAVPPFTREQWRELISLEINDVQRLPEKTR
LKIKRPVKVQPIARVWYQEQQKQVQHPCPMPLIAFCQRQSGAELPKLGELTDYDVKHIKHKYKPDAKPLRLLVPRLHLYV
ELEP

Sequences:

>Translated_324_residues
MYVVTKPPYLEKNMNKYDLIERMNTRFAELEVTLHQLHQQLDDLPLIAARVFSLPEIEKGTEHQPIEQITVNITEGEHAK
RLGLQHFQRLFLHHQGQHVSSKAALRLPGVLCFSVTDKELIECQDIIKKTNQLKAELEHIITVESGLPSEQRFEFVHTHL
HGLITLNTYRTITPLINPSSVRFGWANKHIIKNVTREDILLQLEKSLNAGRAVPPFTREQWRELISLEINDVQRLPEKTR
LKIKRPVKVQPIARVWYQEQQKQVQHPCPMPLIAFCQRQSGAELPKLGELTDYDVKHIKHKYKPDAKPLRLLVPRLHLYV
ELEP
>Mature_324_residues
MYVVTKPPYLEKNMNKYDLIERMNTRFAELEVTLHQLHQQLDDLPLIAARVFSLPEIEKGTEHQPIEQITVNITEGEHAK
RLGLQHFQRLFLHHQGQHVSSKAALRLPGVLCFSVTDKELIECQDIIKKTNQLKAELEHIITVESGLPSEQRFEFVHTHL
HGLITLNTYRTITPLINPSSVRFGWANKHIIKNVTREDILLQLEKSLNAGRAVPPFTREQWRELISLEINDVQRLPEKTR
LKIKRPVKVQPIARVWYQEQQKQVQHPCPMPLIAFCQRQSGAELPKLGELTDYDVKHIKHKYKPDAKPLRLLVPRLHLYV
ELEP

Specific function: Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tus family [H]

Homologues:

Organism=Escherichia coli, GI1787895, Length=307, Percent_Identity=53.7459283387622, Blast_Score=345, Evalue=2e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008865 [H]

Pfam domain/function: PF05472 Ter [H]

EC number: NA

Molecular weight: Translated: 37765; Mature: 37765

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYVVTKPPYLEKNMNKYDLIERMNTRFAELEVTLHQLHQQLDDLPLIAARVFSLPEIEKG
CEEECCCCCHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCC
TEHQPIEQITVNITEGEHAKRLGLQHFQRLFLHHQGQHVSSKAALRLPGVLCFSVTDKEL
CCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCEEEEECCCHHH
IECQDIIKKTNQLKAELEHIITVESGLPSEQRFEFVHTHLHGLITLNTYRTITPLINPSS
HHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHEEEEECCCEECCCCCCCC
VRFGWANKHIIKNVTREDILLQLEKSLNAGRAVPPFTREQWRELISLEINDVQRLPEKTR
EEECCCCHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCHHHHHHCCHHHC
LKIKRPVKVQPIARVWYQEQQKQVQHPCPMPLIAFCQRQSGAELPKLGELTDYDVKHIKH
EEECCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
KYKPDAKPLRLLVPRLHLYVELEP
HCCCCCCHHHHHCCEEEEEEEECC
>Mature Secondary Structure
MYVVTKPPYLEKNMNKYDLIERMNTRFAELEVTLHQLHQQLDDLPLIAARVFSLPEIEKG
CEEECCCCCHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCC
TEHQPIEQITVNITEGEHAKRLGLQHFQRLFLHHQGQHVSSKAALRLPGVLCFSVTDKEL
CCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCEEEEECCCHHH
IECQDIIKKTNQLKAELEHIITVESGLPSEQRFEFVHTHLHGLITLNTYRTITPLINPSS
HHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHEEEEECCCEECCCCCCCC
VRFGWANKHIIKNVTREDILLQLEKSLNAGRAVPPFTREQWRELISLEINDVQRLPEKTR
EEECCCCHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCHHHHHHCCHHHC
LKIKRPVKVQPIARVWYQEQQKQVQHPCPMPLIAFCQRQSGAELPKLGELTDYDVKHIKH
EEECCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
KYKPDAKPLRLLVPRLHLYVELEP
HCCCCCCHHHHHCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA