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The map label for this gene is mrkC [H]

Identifier: 170024027

GI number: 170024027

Start: 1984467

End: 1987079

Strand: Direct

Name: mrkC [H]

Synonym: YPK_1788

Alternate gene names: 170024027

Gene position: 1984467-1987079 (Clockwise)

Preceding gene: 170024026

Following gene: 170024028

Centisome position: 42.32

GC content: 49.41

Gene sequence:

>2613_bases
ATGCTTAGTGCTTTCATATTTTTTCAAAAAAACGAGTGCCTAAAATATTTACCGGCATTCTCTTTCGCTATTTGTGGTAT
TGGTGGCATGTTATATATTCCGTCATCTGCCGCCGAGAATTCTGAATACGTTGAATTTAGTGACGCCTTCCTCCGTTTTC
CCGTTGATGCCACCCGCTACAGTGAGGGTAATCCTGTTTCCCCCGGTGAGCGTCAGGTTGATATCTATTTAAATGATCAA
TGGATTGGTCGTCAGGAAATGCGTTTTGCCTTGCCGTCGCCAGAATCGAAAGTTGCCACCCCCTGTTTTGACGTAAAACT
CTTTGATGAGTTGGGGGTTGATACGGCGAAGTTATCTTCCGATACCGTGAAATTGCTCGAAAGTCGCGGGGCATGCTCTC
CGTTGAGTCGTTTGCTGGAAGGTGGAAATGCTATTTTTGACGACAATCAGCAACGCTTGGATATTCAGGTTCCTCAAGCT
TATCTGATCCGCCAGGCTCGCGGTTATGTGCATCCTAAATATTGGGATGATGGCGTGACAGCGGCCACCTTGAAATATGA
CTATACCGGTTACCGCAGTAACCAGAATGATATCGGTAGCCAGACTTATCAATATCTGGGGCTCTTGGGCGGGCTTAACT
GGCAAAGCTGGCGTCTATATTACCGCAGTGCATTGAATCGAAGTGATAGCCAAGGCTTTGATTATCAGAACCTGGCCACT
TATGTTGAACGGGCCGTTCCCTCGCTATACAGCAAAATGACTATTGGTGATTCAAACACGGATGGTCAGGTGTTCGACAG
CCTTAGCTATCGCGGCATTGAGTTGACCTCAGATGACCGGATGTATGCGGATTCTCAGCGGGGTTATGCGCCAGTGGTAC
GGGGTGTTGCTCGAACGAACGCCCGCGTCGTGGTGCGTCAACAGGGGCGGCCTATTTATGAAACGACGGTACCCCCAGGG
CCTTTTGTCATTGACGACCTCTACCCGACCGGTCAGGGGGGCAATCTCAATGTCACCATTACCGAAGCGGATGGCAGCGA
ACAGACATTTATCGTTCCTTTTGCCTCGATAGCGGAGTTGCTGCGACCGGGAACCACGCGTTACTCATTGATGGCCGGTG
AGTATCGTGACAATTCGATGGTAGATAAACCGGTTCTCTTTATGGGAACGGTGCGTCATGGGTTATCCAATTTACTCACC
GGTAACGGCGGGATGGTTGCGGCTGAAGGCTATTTATCAGCCTCTGCCGGGTTGGCATTTAACACACCGGTTGGTGCCGT
GGCATTTAATGTGACGCAAGCACAAACCCGTCTGCCTAATAAAGATAATCAACGTGGGCAAAGTATTGGTATGACCTATG
CTAAATCCTTGCCGGAAACCAATACCAACTTGACCATCGCCAGTTATCACTATTCCAGTAACGGTTTTTATACCCCAGCA
GAAGCTATGCGAATGCGTGATTATTTACAGCATGGTGAAGTCAATAATACGCAGATTGATTCAAGTTGGCCGAATGGCAG
TGATCGCTACGATGATAGTTTTAAGTATCGTCGCCGCAATCAGGCGCAAGTGAGTATCGCTCAGGGCTTACCTGATGGCT
ATGGCTCGTTCTACGCAAATGCCAATGTGCAGGATTACTGGGATGGGCGTAACCGCGATATGAATTTTCAATTCGGCTAC
ACGAATAGCTATAAGTCGCTGAGTTATAACGTGGCGCTTAATCGCTTGCGTGATATACCTAGCGGCGATTGGGACAACCA
ATTAAGTGTTTCCCTTTCGATTCCTCTGGGGACACATGCTGGTGCACCACGTTTGAGCTCCAGTTATTCCAATACTCGTG
GTAGCAGTGCAATACAAACCGGGGTTTCCGGCTCTGCGGGTGAGGATAATCAATTTAGCTATGGCGTATCTGCAGCGAAT
AACCGTAGCGATGAAAATGGCAGTTATAACACCCTAGGTGCGAATGGCAGTTGGCAGGCACCTTACGCCACGGTGGGCGG
TAGTTATTCGAAGAGTAACAGCTATGATCAAGCCAGTGCCAGCTTGTCAGGGGGGGTAGTGGCTTATCGTGGTGGGGTGA
TATTGGCCCCTGCACTGGGTGATACCGTCGGTATTATTGAGGCTCCAGATGCTGCGGGAGCGCGAGTCGGCAGCTACTCC
AGTATGTATCTTGATCGTCGTGGGCGTGCGATATTGCCTTATTTAAGTCCGTATCGGCAGAATGAGGTTGAATTAGATCC
GAAAGGGCTATCTGCAGATGTTGAGTTTAAAAGTACTAGCCAAAAAGTTGCGCCAACCGCAGGTGCTGTTGCATTGGTAA
CATTCGAGACCTCAACCGGTTATTCGGTTTTAGTCAGGGGGCATCTGGCAGATAACACCCCCTTGCCGTTTGGGGCGGAA
GTAAAAGATGGCGGAGGGACCCGCGTCGGCTTTATTGCTCAGGGCGGTCAGGCAATGGTCCGAGTGAATCAACAAGCCGG
TAATCTGCGCGTGATATGGGGTGATGGCATCGGTGAGAGTTGCAGTTTTGACTATAAATTGCCGGAAGGTAACCTAGTAA
AAGGTCATCTGGTCAAAGGTGACTACCGGCGCTTAGAGGTGATATGCAAATGA

Upstream 100 bases:

>100_bases
GCAAAAACTGACCCAATAAAACTATAAAAAATACAAATTAAGGGTAATTTGTATTTTTTGCACTTTTATATACTGCATTT
AATTTAATGGCCTCGATATA

Downstream 100 bases:

>100_bases
GTGCTTATTTCTATAGGGTGAAAACAGTGATTCGGCATATCAACATGTACCTGCGCGTTTATGCTCATGTCCGTTCTGTT
GCTACGCTACTGATATTGGT

Product: fimbrial biogenesis outer membrane usher protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 870; Mature: 870

Protein sequence:

>870_residues
MLSAFIFFQKNECLKYLPAFSFAICGIGGMLYIPSSAAENSEYVEFSDAFLRFPVDATRYSEGNPVSPGERQVDIYLNDQ
WIGRQEMRFALPSPESKVATPCFDVKLFDELGVDTAKLSSDTVKLLESRGACSPLSRLLEGGNAIFDDNQQRLDIQVPQA
YLIRQARGYVHPKYWDDGVTAATLKYDYTGYRSNQNDIGSQTYQYLGLLGGLNWQSWRLYYRSALNRSDSQGFDYQNLAT
YVERAVPSLYSKMTIGDSNTDGQVFDSLSYRGIELTSDDRMYADSQRGYAPVVRGVARTNARVVVRQQGRPIYETTVPPG
PFVIDDLYPTGQGGNLNVTITEADGSEQTFIVPFASIAELLRPGTTRYSLMAGEYRDNSMVDKPVLFMGTVRHGLSNLLT
GNGGMVAAEGYLSASAGLAFNTPVGAVAFNVTQAQTRLPNKDNQRGQSIGMTYAKSLPETNTNLTIASYHYSSNGFYTPA
EAMRMRDYLQHGEVNNTQIDSSWPNGSDRYDDSFKYRRRNQAQVSIAQGLPDGYGSFYANANVQDYWDGRNRDMNFQFGY
TNSYKSLSYNVALNRLRDIPSGDWDNQLSVSLSIPLGTHAGAPRLSSSYSNTRGSSAIQTGVSGSAGEDNQFSYGVSAAN
NRSDENGSYNTLGANGSWQAPYATVGGSYSKSNSYDQASASLSGGVVAYRGGVILAPALGDTVGIIEAPDAAGARVGSYS
SMYLDRRGRAILPYLSPYRQNEVELDPKGLSADVEFKSTSQKVAPTAGAVALVTFETSTGYSVLVRGHLADNTPLPFGAE
VKDGGGTRVGFIAQGGQAMVRVNQQAGNLRVIWGDGIGESCSFDYKLPEGNLVKGHLVKGDYRRLEVICK

Sequences:

>Translated_870_residues
MLSAFIFFQKNECLKYLPAFSFAICGIGGMLYIPSSAAENSEYVEFSDAFLRFPVDATRYSEGNPVSPGERQVDIYLNDQ
WIGRQEMRFALPSPESKVATPCFDVKLFDELGVDTAKLSSDTVKLLESRGACSPLSRLLEGGNAIFDDNQQRLDIQVPQA
YLIRQARGYVHPKYWDDGVTAATLKYDYTGYRSNQNDIGSQTYQYLGLLGGLNWQSWRLYYRSALNRSDSQGFDYQNLAT
YVERAVPSLYSKMTIGDSNTDGQVFDSLSYRGIELTSDDRMYADSQRGYAPVVRGVARTNARVVVRQQGRPIYETTVPPG
PFVIDDLYPTGQGGNLNVTITEADGSEQTFIVPFASIAELLRPGTTRYSLMAGEYRDNSMVDKPVLFMGTVRHGLSNLLT
GNGGMVAAEGYLSASAGLAFNTPVGAVAFNVTQAQTRLPNKDNQRGQSIGMTYAKSLPETNTNLTIASYHYSSNGFYTPA
EAMRMRDYLQHGEVNNTQIDSSWPNGSDRYDDSFKYRRRNQAQVSIAQGLPDGYGSFYANANVQDYWDGRNRDMNFQFGY
TNSYKSLSYNVALNRLRDIPSGDWDNQLSVSLSIPLGTHAGAPRLSSSYSNTRGSSAIQTGVSGSAGEDNQFSYGVSAAN
NRSDENGSYNTLGANGSWQAPYATVGGSYSKSNSYDQASASLSGGVVAYRGGVILAPALGDTVGIIEAPDAAGARVGSYS
SMYLDRRGRAILPYLSPYRQNEVELDPKGLSADVEFKSTSQKVAPTAGAVALVTFETSTGYSVLVRGHLADNTPLPFGAE
VKDGGGTRVGFIAQGGQAMVRVNQQAGNLRVIWGDGIGESCSFDYKLPEGNLVKGHLVKGDYRRLEVICK
>Mature_870_residues
MLSAFIFFQKNECLKYLPAFSFAICGIGGMLYIPSSAAENSEYVEFSDAFLRFPVDATRYSEGNPVSPGERQVDIYLNDQ
WIGRQEMRFALPSPESKVATPCFDVKLFDELGVDTAKLSSDTVKLLESRGACSPLSRLLEGGNAIFDDNQQRLDIQVPQA
YLIRQARGYVHPKYWDDGVTAATLKYDYTGYRSNQNDIGSQTYQYLGLLGGLNWQSWRLYYRSALNRSDSQGFDYQNLAT
YVERAVPSLYSKMTIGDSNTDGQVFDSLSYRGIELTSDDRMYADSQRGYAPVVRGVARTNARVVVRQQGRPIYETTVPPG
PFVIDDLYPTGQGGNLNVTITEADGSEQTFIVPFASIAELLRPGTTRYSLMAGEYRDNSMVDKPVLFMGTVRHGLSNLLT
GNGGMVAAEGYLSASAGLAFNTPVGAVAFNVTQAQTRLPNKDNQRGQSIGMTYAKSLPETNTNLTIASYHYSSNGFYTPA
EAMRMRDYLQHGEVNNTQIDSSWPNGSDRYDDSFKYRRRNQAQVSIAQGLPDGYGSFYANANVQDYWDGRNRDMNFQFGY
TNSYKSLSYNVALNRLRDIPSGDWDNQLSVSLSIPLGTHAGAPRLSSSYSNTRGSSAIQTGVSGSAGEDNQFSYGVSAAN
NRSDENGSYNTLGANGSWQAPYATVGGSYSKSNSYDQASASLSGGVVAYRGGVILAPALGDTVGIIEAPDAAGARVGSYS
SMYLDRRGRAILPYLSPYRQNEVELDPKGLSADVEFKSTSQKVAPTAGAVALVTFETSTGYSVLVRGHLADNTPLPFGAE
VKDGGGTRVGFIAQGGQAMVRVNQQAGNLRVIWGDGIGESCSFDYKLPEGNLVKGHLVKGDYRRLEVICK

Specific function: Involved in the export and assembly of the type 3 fimbrial subunit (mrkA) [H]

COG id: COG3188

COG function: function code NU; P pilus assembly protein, porin PapC

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fimbrial export usher family [H]

Homologues:

Organism=Escherichia coli, GI1786332, Length=835, Percent_Identity=36.2874251497006, Blast_Score=474, Evalue=1e-134,
Organism=Escherichia coli, GI1790772, Length=812, Percent_Identity=34.6059113300493, Blast_Score=455, Evalue=1e-129,
Organism=Escherichia coli, GI1787172, Length=875, Percent_Identity=34.1714285714286, Blast_Score=436, Evalue=1e-123,
Organism=Escherichia coli, GI1786744, Length=863, Percent_Identity=31.5179606025492, Blast_Score=422, Evalue=1e-119,
Organism=Escherichia coli, GI1788427, Length=827, Percent_Identity=30.9552599758162, Blast_Score=408, Evalue=1e-115,
Organism=Escherichia coli, GI1789533, Length=802, Percent_Identity=31.1720698254364, Blast_Score=397, Evalue=1e-111,
Organism=Escherichia coli, GI87081778, Length=862, Percent_Identity=27.8422273781903, Blast_Score=253, Evalue=3e-68,
Organism=Escherichia coli, GI1789610, Length=807, Percent_Identity=25.1548946716233, Blast_Score=157, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000015
- InterPro:   IPR018030 [H]

Pfam domain/function: PF00577 Usher [H]

EC number: NA

Molecular weight: Translated: 94919; Mature: 94919

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS01151 FIMBRIAL_USHER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSAFIFFQKNECLKYLPAFSFAICGIGGMLYIPSSAAENSEYVEFSDAFLRFPVDATRY
CCEEEEEEECCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEECCCEEECCCCHHCC
SEGNPVSPGERQVDIYLNDQWIGRQEMRFALPSPESKVATPCFDVKLFDELGVDTAKLSS
CCCCCCCCCCEEEEEEECCCCCCHHHHEEECCCCCCCCCCCEEEEEEHHHCCCCHHHCCH
DTVKLLESRGACSPLSRLLEGGNAIFDDNQQRLDIQVPQAYLIRQARGYVHPKYWDDGVT
HHHHHHHCCCCHHHHHHHHHCCCEEECCCCCEEEEECCHHHHHHHHCCCCCCCEECCCCE
AATLKYDYTGYRSNQNDIGSQTYQYLGLLGGLNWQSWRLYYRSALNRSDSQGFDYQNLAT
EEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHH
YVERAVPSLYSKMTIGDSNTDGQVFDSLSYRGIELTSDDRMYADSQRGYAPVVRGVARTN
HHHHHHHHHHHEEECCCCCCCCHHHHCCCCCCEEECCCCCEECCCCCCHHHHHHHHHCCC
ARVVVRQQGRPIYETTVPPGPFVIDDLYPTGQGGNLNVTITEADGSEQTFIVPFASIAEL
CEEEEEECCCEEEECCCCCCCEEEECCCCCCCCCEEEEEEEECCCCCCEEEEEHHHHHHH
LRPGTTRYSLMAGEYRDNSMVDKPVLFMGTVRHGLSNLLTGNGGMVAAEGYLSASAGLAF
HCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCEECCCCEEE
NTPVGAVAFNVTQAQTRLPNKDNQRGQSIGMTYAKSLPETNTNLTIASYHYSSNGFYTPA
CCCCCEEEEEEEHHHHCCCCCCCCCCCHHCHHHHHCCCCCCCCEEEEEEEECCCCEECHH
EAMRMRDYLQHGEVNNTQIDSSWPNGSDRYDDSFKYRRRNQAQVSIAQGLPDGYGSFYAN
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCEEEEECCCCCCCCCEEEC
ANVQDYWDGRNRDMNFQFGYTNSYKSLSYNVALNRLRDIPSGDWDNQLSVSLSIPLGTHA
CCCHHCCCCCCCCEEEEECCCCCCCCEEEHHHHHHHHCCCCCCCCCEEEEEEEECCCCCC
GAPRLSSSYSNTRGSSAIQTGVSGSAGEDNQFSYGVSAANNRSDENGSYNTLGANGSWQA
CCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCCCEEEECCCCCCCC
PYATVGGSYSKSNSYDQASASLSGGVVAYRGGVILAPALGDTVGIIEAPDAAGARVGSYS
CEEECCCCCCCCCCCCHHHHHCCCCEEEEECCEEEEECCCCEEEEEECCCCCCCCCCCCH
SMYLDRRGRAILPYLSPYRQNEVELDPKGLSADVEFKSTSQKVAPTAGAVALVTFETSTG
HEEECCCCCEEECCCCCCCCCCEEECCCCCCEEEEECCCCCCCCCCCCEEEEEEEECCCC
YSVLVRGHLADNTPLPFGAEVKDGGGTRVGFIAQGGQAMVRVNQQAGNLRVIWGDGIGES
EEEEEEEECCCCCCCCCCCEEECCCCCEEEEEECCCEEEEEEECCCCCEEEEECCCCCCC
CSFDYKLPEGNLVKGHLVKGDYRRLEVICK
CEEEEECCCCCEEEEEEECCCCEEEEEEEC
>Mature Secondary Structure
MLSAFIFFQKNECLKYLPAFSFAICGIGGMLYIPSSAAENSEYVEFSDAFLRFPVDATRY
CCEEEEEEECCHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEECCCEEECCCCHHCC
SEGNPVSPGERQVDIYLNDQWIGRQEMRFALPSPESKVATPCFDVKLFDELGVDTAKLSS
CCCCCCCCCCEEEEEEECCCCCCHHHHEEECCCCCCCCCCCEEEEEEHHHCCCCHHHCCH
DTVKLLESRGACSPLSRLLEGGNAIFDDNQQRLDIQVPQAYLIRQARGYVHPKYWDDGVT
HHHHHHHCCCCHHHHHHHHHCCCEEECCCCCEEEEECCHHHHHHHHCCCCCCCEECCCCE
AATLKYDYTGYRSNQNDIGSQTYQYLGLLGGLNWQSWRLYYRSALNRSDSQGFDYQNLAT
EEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHH
YVERAVPSLYSKMTIGDSNTDGQVFDSLSYRGIELTSDDRMYADSQRGYAPVVRGVARTN
HHHHHHHHHHHEEECCCCCCCCHHHHCCCCCCEEECCCCCEECCCCCCHHHHHHHHHCCC
ARVVVRQQGRPIYETTVPPGPFVIDDLYPTGQGGNLNVTITEADGSEQTFIVPFASIAEL
CEEEEEECCCEEEECCCCCCCEEEECCCCCCCCCEEEEEEEECCCCCCEEEEEHHHHHHH
LRPGTTRYSLMAGEYRDNSMVDKPVLFMGTVRHGLSNLLTGNGGMVAAEGYLSASAGLAF
HCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCEECCCCEEE
NTPVGAVAFNVTQAQTRLPNKDNQRGQSIGMTYAKSLPETNTNLTIASYHYSSNGFYTPA
CCCCCEEEEEEEHHHHCCCCCCCCCCCHHCHHHHHCCCCCCCCEEEEEEEECCCCEECHH
EAMRMRDYLQHGEVNNTQIDSSWPNGSDRYDDSFKYRRRNQAQVSIAQGLPDGYGSFYAN
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCEEEEECCCCCCCCCEEEC
ANVQDYWDGRNRDMNFQFGYTNSYKSLSYNVALNRLRDIPSGDWDNQLSVSLSIPLGTHA
CCCHHCCCCCCCCEEEEECCCCCCCCEEEHHHHHHHHCCCCCCCCCEEEEEEEECCCCCC
GAPRLSSSYSNTRGSSAIQTGVSGSAGEDNQFSYGVSAANNRSDENGSYNTLGANGSWQA
CCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCCCEEEECCCCCCCC
PYATVGGSYSKSNSYDQASASLSGGVVAYRGGVILAPALGDTVGIIEAPDAAGARVGSYS
CEEECCCCCCCCCCCCHHHHHCCCCEEEEECCEEEEECCCCEEEEEECCCCCCCCCCCCH
SMYLDRRGRAILPYLSPYRQNEVELDPKGLSADVEFKSTSQKVAPTAGAVALVTFETSTG
HEEECCCCCEEECCCCCCCCCCEEECCCCCCEEEEECCCCCCCCCCCCEEEEEEEECCCC
YSVLVRGHLADNTPLPFGAEVKDGGGTRVGFIAQGGQAMVRVNQQAGNLRVIWGDGIGES
EEEEEEEECCCCCCCCCCCEEECCCCCEEEEEECCCEEEEEEECCCCCEEEEECCCCCCC
CSFDYKLPEGNLVKGHLVKGDYRRLEVICK
CEEEEECCCCCEEEEEEECCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1670938 [H]