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The map label for this gene is yadA [H]

Identifier: 170024000

GI number: 170024000

Start: 1956058

End: 1958688

Strand: Direct

Name: yadA [H]

Synonym: YPK_1761

Alternate gene names: 170024000

Gene position: 1956058-1958688 (Clockwise)

Preceding gene: 170023999

Following gene: 170024001

Centisome position: 41.71

GC content: 57.47

Gene sequence:

>2631_bases
ATGAAAAGTATCCAAAAGTGTGACTGTAATTATCTGGCCAGATTTGCAGTTTCAGATTCCTTTATCAGAGACAATTCTTT
TCGCAGCTTGCTTGCTATTTTTATGGTGACGATATTTGTGCCAAATACTGCATTTTCTCAACTCTATGTGAACAATGCCA
ATGATCCTGGCTGTTATGTCATTGCTGATGGGGGGTTTACGGGTGTTACTAATAGTGATCAAAATTGTTATACGTTGTCT
TTGAATAATATTAATACCAATGGGGGGCAGCTATTTGTTGGTGGAAAAGGTGGGATCGCTGGGAAGCCTAGCTTTATCGC
CACCCCTTGGACAGGGACATTCACGACGGCCGTTGGCACCAGTAATGTCGCCACAGCATACGGCTTTGTCGTTCAAAACA
ATGGTGCATTTATCAACGGTGATACCTACGTGCAGGGGGGGTTATTTTTGAATGGTAGGAAAGCCACCAATCTTGCCCCC
GCAACGATTTCATCGACCTCCACCGATGCGGTGGTTGGTAGCCAGCTTTATACGGTGATCCAAGATGGAACCCGCTATTT
CCACGCCAACTCAGTGAACCCGCAAGACTCCGTGCCTGCGGGTCAGGATGCTATTGCTGTCGGGCCGGCGACGGTGGTCA
ATGGTAATAACGGGATTGGTATTGGTAATAGCGCCGTTGTTGGGCCGAGTGCTGTCGGGGGCATTGCAATTGGCCCCAAC
ACTCAGGCGACCGGTACCGCCAGCACGGCCCTTGGTGCCGGAACGCAGGCGCAGGGGGCACAGTCTTTGGCTCTTGGGGC
CGGGGCGGTTACCCGCCAGGTAAACAGTATTGCGTTAGGGGCGTCGTCGGTCACCACGGTGGGCGCTCAGGGCAGCTACA
GTGCATACGGACTGCCGACCACGCAGGCGTCGGTGGGGGAAGTGGGCATAGGGACCGCGCAGGGTAATCGCAAGATCACC
GGTGTGGCAGCCGGTTCGGCTGGTTATGATGCGGTCAACGTGACTCAGTTGACTGCTGTTGGTAATAAAGTCGACCAAAA
TACCGCTGACATTACCAGTTTAGACGGCCGGGTCACCAATGTTGAGGGGGGGATGACCAGCATCACCAACGGGGGCGGTA
TAAAGTACTTCCACACTCACTCCACCGAGCCTGATTCGGTGGCCAGCGGCAGTGATTCGGTGGCGATCGGACCGAATGCG
CAGGCGTCCGGTACCACGTCGATAGCCATGGGGGCCGGGTCGACAGCGCAGGGAGCACAGTCTCTGGCATTGGGGGCGGG
AGCGGCTGCCAGCCAGGCAAACAGTATTGCGTTAGGGGCGTCATCGGTCACCACGGTCGGTGCTGAGAGCAACTACAGTG
CGTACGGACTGACAGCTTCCCAAACGTCGGTGGGCGAGGTGGGGGTGGGCACGGCACAGGGGAATCGCAAGATCACCGGT
GTGGCAGCCGGTTCGGCTGATTATGATGCGGTCAATGTCGCGCAATTGACCGCTGTTGGTGACAAGGTCGATCAGAATAC
CGCTGACATCACCAGTTTAGACGGCCGGGTCACCAATGTTGAGGGGGAGATGACCAGCATCACCAACGGGGGCGGCGTGA
AATACTTCCACACCCACTCCACCGAGCCTGATTCGGTGGCCAGCGGCAGTGATTCGGTGGCGATCGGACCGAATGCGCAG
GCGTCAGGTACGGCTTCGGTGGCCTCCGGCAAGGGTACGCTGGCCTCCGGTAACGGTGCGGTGGCGATAGGTGATGCAGC
AAGCGTCAGCGCAGAGGGCAGTGTTGCCCTGGGGCAGGGTTCCGCTGACAACGGGCGCGGTGCAGAGAGCTACACCGGCA
AGTACTCCACTACGGATAACACCACCTCAGGTACGGTGTCGGTGGGCAATGCGGCAACCGGGGAGACCCGGACGGTCAGC
AACGTTGCCGACGGGCGAGAGGCCATGGATGCAGTCAATCTGCGGCAACTCGATGGTGCAATGGCGGCGGTGGGTGACAC
CGTATCAGGGTTGCAGAACGGCACTGACGGGATGTTCCAGGTGAACAACAACAGCGGTCAGGCCAAGCCTTCGGCCACCG
GAACTGATGCGATGGCGGGGGGGGCAGGCTCCGTGGCGTCTGGCAGCCACAGTACCGCGATGGGTACGGGCAGCAAGGCG
ACGGCGGCAAACAGCACCGCGCTGGGGGCCAACTCAGTGGCGGATCGTGAAAACAGTGTCTCGGTGGGGTCAGTGGGTAA
TGAACGGCAGCTCACTAATATTGCTGTGGGGACTCAGGGCACTGATGCGGTGAATCTGGATCAACTCAACCATAGCATGT
CGAATGTCACCAACGACGCCAATGCTTATACAGACCAGCGCTATTCTGCACTTAAAGAAGATCTGAAAAAACAGGATAGT
ACGTTAAGTGCGGGGATCGCCGGTGCCATGGCGATGGCGAGCCTGACTCAACCCTATACGCCGGGTGCCAGCATGGCGAC
CATTGGTGCGGCCAGCTATCGGGGCCAGTCGGCGCTGTCGGTGGGGGTGTCGAGTATTTCTGACAGTGGGCGATGGGTCA
GCAAATTGCAGGCCTCCTCTAATACACAAGGCGATATGGGGGTTGGTGTCGGCGTCGGTTATCAATGGTAA

Upstream 100 bases:

>100_bases
CTTCGATTCACTCAGTGCCATACAGGAGCGGGTTTGAACGTCTTTGCTTAATAATTTGTCACCAATGTCAAAAGGTGAAC
AAGAATAAAATGGGGATGGT

Downstream 100 bases:

>100_bases
AGAAAGGCCAACACTGAATATTGTTTAATAATCATTAACGGGTTGTGCGATTTTTTGCACAGCCCGATTCTACTTCTTAG
GGATTAAAAGGCAGCACCCA

Product: YadA domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 876; Mature: 876

Protein sequence:

>876_residues
MKSIQKCDCNYLARFAVSDSFIRDNSFRSLLAIFMVTIFVPNTAFSQLYVNNANDPGCYVIADGGFTGVTNSDQNCYTLS
LNNINTNGGQLFVGGKGGIAGKPSFIATPWTGTFTTAVGTSNVATAYGFVVQNNGAFINGDTYVQGGLFLNGRKATNLAP
ATISSTSTDAVVGSQLYTVIQDGTRYFHANSVNPQDSVPAGQDAIAVGPATVVNGNNGIGIGNSAVVGPSAVGGIAIGPN
TQATGTASTALGAGTQAQGAQSLALGAGAVTRQVNSIALGASSVTTVGAQGSYSAYGLPTTQASVGEVGIGTAQGNRKIT
GVAAGSAGYDAVNVTQLTAVGNKVDQNTADITSLDGRVTNVEGGMTSITNGGGIKYFHTHSTEPDSVASGSDSVAIGPNA
QASGTTSIAMGAGSTAQGAQSLALGAGAAASQANSIALGASSVTTVGAESNYSAYGLTASQTSVGEVGVGTAQGNRKITG
VAAGSADYDAVNVAQLTAVGDKVDQNTADITSLDGRVTNVEGEMTSITNGGGVKYFHTHSTEPDSVASGSDSVAIGPNAQ
ASGTASVASGKGTLASGNGAVAIGDAASVSAEGSVALGQGSADNGRGAESYTGKYSTTDNTTSGTVSVGNAATGETRTVS
NVADGREAMDAVNLRQLDGAMAAVGDTVSGLQNGTDGMFQVNNNSGQAKPSATGTDAMAGGAGSVASGSHSTAMGTGSKA
TAANSTALGANSVADRENSVSVGSVGNERQLTNIAVGTQGTDAVNLDQLNHSMSNVTNDANAYTDQRYSALKEDLKKQDS
TLSAGIAGAMAMASLTQPYTPGASMATIGAASYRGQSALSVGVSSISDSGRWVSKLQASSNTQGDMGVGVGVGYQW

Sequences:

>Translated_876_residues
MKSIQKCDCNYLARFAVSDSFIRDNSFRSLLAIFMVTIFVPNTAFSQLYVNNANDPGCYVIADGGFTGVTNSDQNCYTLS
LNNINTNGGQLFVGGKGGIAGKPSFIATPWTGTFTTAVGTSNVATAYGFVVQNNGAFINGDTYVQGGLFLNGRKATNLAP
ATISSTSTDAVVGSQLYTVIQDGTRYFHANSVNPQDSVPAGQDAIAVGPATVVNGNNGIGIGNSAVVGPSAVGGIAIGPN
TQATGTASTALGAGTQAQGAQSLALGAGAVTRQVNSIALGASSVTTVGAQGSYSAYGLPTTQASVGEVGIGTAQGNRKIT
GVAAGSAGYDAVNVTQLTAVGNKVDQNTADITSLDGRVTNVEGGMTSITNGGGIKYFHTHSTEPDSVASGSDSVAIGPNA
QASGTTSIAMGAGSTAQGAQSLALGAGAAASQANSIALGASSVTTVGAESNYSAYGLTASQTSVGEVGVGTAQGNRKITG
VAAGSADYDAVNVAQLTAVGDKVDQNTADITSLDGRVTNVEGEMTSITNGGGVKYFHTHSTEPDSVASGSDSVAIGPNAQ
ASGTASVASGKGTLASGNGAVAIGDAASVSAEGSVALGQGSADNGRGAESYTGKYSTTDNTTSGTVSVGNAATGETRTVS
NVADGREAMDAVNLRQLDGAMAAVGDTVSGLQNGTDGMFQVNNNSGQAKPSATGTDAMAGGAGSVASGSHSTAMGTGSKA
TAANSTALGANSVADRENSVSVGSVGNERQLTNIAVGTQGTDAVNLDQLNHSMSNVTNDANAYTDQRYSALKEDLKKQDS
TLSAGIAGAMAMASLTQPYTPGASMATIGAASYRGQSALSVGVSSISDSGRWVSKLQASSNTQGDMGVGVGVGYQW
>Mature_876_residues
MKSIQKCDCNYLARFAVSDSFIRDNSFRSLLAIFMVTIFVPNTAFSQLYVNNANDPGCYVIADGGFTGVTNSDQNCYTLS
LNNINTNGGQLFVGGKGGIAGKPSFIATPWTGTFTTAVGTSNVATAYGFVVQNNGAFINGDTYVQGGLFLNGRKATNLAP
ATISSTSTDAVVGSQLYTVIQDGTRYFHANSVNPQDSVPAGQDAIAVGPATVVNGNNGIGIGNSAVVGPSAVGGIAIGPN
TQATGTASTALGAGTQAQGAQSLALGAGAVTRQVNSIALGASSVTTVGAQGSYSAYGLPTTQASVGEVGIGTAQGNRKIT
GVAAGSAGYDAVNVTQLTAVGNKVDQNTADITSLDGRVTNVEGGMTSITNGGGIKYFHTHSTEPDSVASGSDSVAIGPNA
QASGTTSIAMGAGSTAQGAQSLALGAGAAASQANSIALGASSVTTVGAESNYSAYGLTASQTSVGEVGVGTAQGNRKITG
VAAGSADYDAVNVAQLTAVGDKVDQNTADITSLDGRVTNVEGEMTSITNGGGVKYFHTHSTEPDSVASGSDSVAIGPNAQ
ASGTASVASGKGTLASGNGAVAIGDAASVSAEGSVALGQGSADNGRGAESYTGKYSTTDNTTSGTVSVGNAATGETRTVS
NVADGREAMDAVNLRQLDGAMAAVGDTVSGLQNGTDGMFQVNNNSGQAKPSATGTDAMAGGAGSVASGSHSTAMGTGSKA
TAANSTALGANSVADRENSVSVGSVGNERQLTNIAVGTQGTDAVNLDQLNHSMSNVTNDANAYTDQRYSALKEDLKKQDS
TLSAGIAGAMAMASLTQPYTPGASMATIGAASYRGQSALSVGVSSISDSGRWVSKLQASSNTQGDMGVGVGVGYQW

Specific function: Collagen-binding outer membrane protein forming a fibrillar matrix on the bacterial cell surface. Promotes attachment to eukaryotic cells and after invasion, is the major adhesin in infected tissue. Constitutes an alternative uptake pathway under conditio

COG id: COG5295

COG function: function code UW; Autotransporter adhesin

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the autotransporter-2 (TC 1.B.40) / oligomeric coiled-coil adhesin (Oca) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008640
- InterPro:   IPR008635
- InterPro:   IPR008126
- InterPro:   IPR005594 [H]

Pfam domain/function: PF05658 Hep_Hag; PF05662 HIM; PF03895 YadA [H]

EC number: NA

Molecular weight: Translated: 86360; Mature: 86360

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSIQKCDCNYLARFAVSDSFIRDNSFRSLLAIFMVTIFVPNTAFSQLYVNNANDPGCYV
CCCHHHCCHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEE
IADGGFTGVTNSDQNCYTLSLNNINTNGGQLFVGGKGGIAGKPSFIATPWTGTFTTAVGT
EECCCEECCCCCCCCEEEEEECCCCCCCCEEEECCCCCCCCCCCEEECCCCCCEEEECCC
SNVATAYGFVVQNNGAFINGDTYVQGGLFLNGRKATNLAPATISSTSTDAVVGSQLYTVI
CCCEEEEEEEEECCCEEECCCEEEECCEEECCCCCCCCCCCEECCCCCCHHHHHHHHHHH
QDGTRYFHANSVNPQDSVPAGQDAIAVGPATVVNGNNGIGIGNSAVVGPSAVGGIAIGPN
HCCCEEEEECCCCCCCCCCCCCCEEEECCEEEEECCCCCCCCCCCEECCCCCCCEEECCC
TQATGTASTALGAGTQAQGAQSLALGAGAVTRQVNSIALGASSVTTVGAQGSYSAYGLPT
CCCCCCCHHHCCCCCCCCCCCCEECCCCHHHHHHHHEEECCCCEEEECCCCCCCCCCCCC
TQASVGEVGIGTAQGNRKITGVAAGSAGYDAVNVTQLTAVGNKVDQNTADITSLDGRVTN
CCCCCCCCEEEECCCCEEEEEEECCCCCCCEEEEEEEEECCCCCCCCCCCEEECCCEEEE
VEGGMTSITNGGGIKYFHTHSTEPDSVASGSDSVAIGPNAQASGTTSIAMGAGSTAQGAQ
ECCCCEEECCCCCEEEEECCCCCCCCCCCCCCCEEECCCCCCCCCEEEEECCCCCCCCCH
SLALGAGAAASQANSIALGASSVTTVGAESNYSAYGLTASQTSVGEVGVGTAQGNRKITG
HHEECCCCCCCCCCEEEECCCCEEEECCCCCCCEEEEECCCCCCCCCCCEECCCCEEEEE
VAAGSADYDAVNVAQLTAVGDKVDQNTADITSLDGRVTNVEGEMTSITNGGGVKYFHTHS
EECCCCCCCCEEEEEEEECCCCCCCCCCCEEECCCEEEECCCCEEEECCCCCEEEEECCC
TEPDSVASGSDSVAIGPNAQASGTASVASGKGTLASGNGAVAIGDAASVSAEGSVALGQG
CCCCCCCCCCCCEEECCCCCCCCCEEEECCCCEEECCCCCEEECCCCCCCCCCCEEECCC
SADNGRGAESYTGKYSTTDNTTSGTVSVGNAATGETRTVSNVADGREAMDAVNLRQLDGA
CCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCEEHHHHHCCHHHHHHHHHHHHCCH
MAAVGDTVSGLQNGTDGMFQVNNNSGQAKPSATGTDAMAGGAGSVASGSHSTAMGTGSKA
HHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCC
TAANSTALGANSVADRENSVSVGSVGNERQLTNIAVGTQGTDAVNLDQLNHSMSNVTNDA
CCCCCCCCCCCCCCCCCCCEEECCCCCCCEEEEEEECCCCCCCEEHHHHHHHHHHCCCCC
NAYTDQRYSALKEDLKKQDSTLSAGIAGAMAMASLTQPYTPGASMATIGAASYRGQSALS
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCEEEECCHHCCCCHHHH
VGVSSISDSGRWVSKLQASSNTQGDMGVGVGVGYQW
HHHHHCCCCCHHHHHHHHCCCCCCCCCEEECCCCCC
>Mature Secondary Structure
MKSIQKCDCNYLARFAVSDSFIRDNSFRSLLAIFMVTIFVPNTAFSQLYVNNANDPGCYV
CCCHHHCCHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEE
IADGGFTGVTNSDQNCYTLSLNNINTNGGQLFVGGKGGIAGKPSFIATPWTGTFTTAVGT
EECCCEECCCCCCCCEEEEEECCCCCCCCEEEECCCCCCCCCCCEEECCCCCCEEEECCC
SNVATAYGFVVQNNGAFINGDTYVQGGLFLNGRKATNLAPATISSTSTDAVVGSQLYTVI
CCCEEEEEEEEECCCEEECCCEEEECCEEECCCCCCCCCCCEECCCCCCHHHHHHHHHHH
QDGTRYFHANSVNPQDSVPAGQDAIAVGPATVVNGNNGIGIGNSAVVGPSAVGGIAIGPN
HCCCEEEEECCCCCCCCCCCCCCEEEECCEEEEECCCCCCCCCCCEECCCCCCCEEECCC
TQATGTASTALGAGTQAQGAQSLALGAGAVTRQVNSIALGASSVTTVGAQGSYSAYGLPT
CCCCCCCHHHCCCCCCCCCCCCEECCCCHHHHHHHHEEECCCCEEEECCCCCCCCCCCCC
TQASVGEVGIGTAQGNRKITGVAAGSAGYDAVNVTQLTAVGNKVDQNTADITSLDGRVTN
CCCCCCCCEEEECCCCEEEEEEECCCCCCCEEEEEEEEECCCCCCCCCCCEEECCCEEEE
VEGGMTSITNGGGIKYFHTHSTEPDSVASGSDSVAIGPNAQASGTTSIAMGAGSTAQGAQ
ECCCCEEECCCCCEEEEECCCCCCCCCCCCCCCEEECCCCCCCCCEEEEECCCCCCCCCH
SLALGAGAAASQANSIALGASSVTTVGAESNYSAYGLTASQTSVGEVGVGTAQGNRKITG
HHEECCCCCCCCCCEEEECCCCEEEECCCCCCCEEEEECCCCCCCCCCCEECCCCEEEEE
VAAGSADYDAVNVAQLTAVGDKVDQNTADITSLDGRVTNVEGEMTSITNGGGVKYFHTHS
EECCCCCCCCEEEEEEEECCCCCCCCCCCEEECCCEEEECCCCEEEECCCCCEEEEECCC
TEPDSVASGSDSVAIGPNAQASGTASVASGKGTLASGNGAVAIGDAASVSAEGSVALGQG
CCCCCCCCCCCCEEECCCCCCCCCEEEECCCCEEECCCCCEEECCCCCCCCCCCEEECCC
SADNGRGAESYTGKYSTTDNTTSGTVSVGNAATGETRTVSNVADGREAMDAVNLRQLDGA
CCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCEEHHHHHCCHHHHHHHHHHHHCCH
MAAVGDTVSGLQNGTDGMFQVNNNSGQAKPSATGTDAMAGGAGSVASGSHSTAMGTGSKA
HHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCC
TAANSTALGANSVADRENSVSVGSVGNERQLTNIAVGTQGTDAVNLDQLNHSMSNVTNDA
CCCCCCCCCCCCCCCCCCCEEECCCCCCCEEEEEEECCCCCCCEEHHHHHHHHHHCCCCC
NAYTDQRYSALKEDLKKQDSTLSAGIAGAMAMASLTQPYTPGASMATIGAASYRGQSALS
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCEEEECCHHCCCCHHHH
VGVSSISDSGRWVSKLQASSNTQGDMGVGVGVGYQW
HHHHHCCCCCHHHHHHHHCCCCCCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3043229; 2761389; 2592347; 1548243; 12183532 [H]