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The map label for this gene is cheA [H]

Identifier: 170023990

GI number: 170023990

Start: 1940323

End: 1942506

Strand: Direct

Name: cheA [H]

Synonym: YPK_1749

Alternate gene names: 170023990

Gene position: 1940323-1942506 (Clockwise)

Preceding gene: 170023989

Following gene: 170023991

Centisome position: 41.38

GC content: 50.41

Gene sequence:

>2184_bases
GTGAGCATGGATATTACCGCGTTTTATCAGACGTTTTTTGATGAAGCAGATGAACTGTTGGCAGATATGGAACAGCATTT
GTTATTGCTGGACCCGCTGACACCTGACAATGAACAGCTTAATGCTATTTTCCGTGCTGCACATTCGATCAAGGGCGGTG
CCGCTACTTTTGGTTTTACGGTATTGCAAGAGACAACTCATCTATTGGAAAACCTGTTGGATGGTGCTCGCCGCGACGAG
ATGCGCTTGAGCACTGAGATCATCAACCTGTTTTTGGAAACGAAAGATATTATGCAGGAACAGTTGGACGCCTACAAAAC
CTCTCAGGAACCTCATTCGGAAAGCTTTGAGTACATTTGTCAGGCGTTGCGCCAATTGGCACTTGATGCTTTAGATCAAC
CTACAACCGAAGATCAACCTACAACCGAAAATCAATCCGCTACCGATCAGCACAGTACGGCCGCCAATACGCAAGCAACG
GCTTCCACCCGCGTATCATCTTCTCTCGCTGGCAACACATCACCCGCGTTGCTTCAAGGCGGGATGCGTATTCGTTTGTC
TGGCCTGAAAGCGCCAGAAATCTCTCTGATGCTGGAGGAACTGGGTAATCTGGGCGAGGTGCAAGATCCCCATCAGGGCG
CTGATAGCCTTGAGGCCACCTTAATAACCTCCGTCAGTGAAGAGGATATTAGCGCGGTATTGTGCTTTGTTCTGGAGCCT
GAGCAGATTAGCTTTGTGTCCGCAGGGGACACAGAGCAGATTTATGCTGAGCAGACCGTTGAATCAGAACAATCATCTGA
GCCAGAACGCTTGTTTGAGCCAGCAATAACCGAGGCATCGGTGATCGCAGAATCGGTTCAGCCGGTGGCAACACCTGCCG
CAACACCTGCCGCAACACCTGCCGTTGAAGTCCAAAGCACGCTGAAAGCTGATGTGCATGCTGCACCAGCTAACGCAGAA
CAGGTCAGGCCTAAAGCGAAAGCCAGTGAATCGACCAGTATCCGTGTAGCGGTAGAAAAAGTGGACCAGCTGATCAACCT
GGTCGGCGAATTGGTTATTACCCAATCGATGCTCGCTCAGCGCTCAGGTTCGCTGGATCCGGTGATCAACGGTGATTTAC
TGAATAGCATGGGGCAGTTGGAACGTAACGCCCGCGATTTGCAAGAATCCGTCATGTCTATCCGGATGATGCCAATGGAG
TATGTATTTAGCCGCTTCCCACGTTTGGTCCGTGATTTAGCCAGCAAGCTCAACAAACAAGTTGAATTGACGCTGTTAGG
CAGTTCGACAGAACTGGATAAGAGTTTGATTGAGCGCATTATCGATCCTCTGACCCACTTGGTGCGCAACAGTCTGGACC
ACGGTATTGAAGAGCCGGCTACTCGTATTGCTGCGGGGAAATCGCCAGTGGGCAACCTGACACTGTCAGCTGAACATCAG
GGCGGAAATATTTGTATCGAAGTCATTGATGATGGTGCTGGCCTGAATCGACAGAGAATTTTGGCGAAAGCACAGTCTCA
AGGGCTGGCAGTCAACGAAAACATGAGCGATGAAGACGTTGGGATGCTTATTTTTGCACCAGGATTCTCTACTGCCGAAC
AAGTCACGGATGTGTCAGGGCGTGGTGTCGGGATGGATGTGGTCAAACGTAACATCCAGGAAATGGGCGGCCATGTACAG
GTCAGTTTTCAGGCCGGTTTAGGTACCTCAATCCGTATCCTGCTGCCATTAACGCTGGCTATCCTTGATGGCATGTCGGT
TAAAGTCAGCAATGAAGTCTTTATCTTGCCATTGAATGCCGTGATGGAGTCACTGCAACCCTTGGCCGAAGACCTACATC
CATTAGCTGGTGGTGAGCGCGTGCTGCAAGTTCGCGGTGAATTTCTACCATTGGTTGAATTGTACCGCGTCTTTGATGTT
AAAAATGCCAAGACGGAAGCCACGCAAGGCATCGTTGTGATTCTACAAAGTGCCGGGCGCCGCTATGCACTGCTGGTAGA
CCAACTGATTGGTCAGCATCAGGTGGTCGTGAAAAATCTGGAAAGTAACTATCGGAAAGTGCCGGGTATTTCTGCCGCCA
CCATTTTGGGTGATGGTAGCGTCGCGCTAATCGTTGATGTGTCAGCGTTGCAGGCCTTAAACCGTGAAAAACGCGTCGCG
GCTGATGAGGTGGTTACCGCATAG

Upstream 100 bases:

>100_bases
ACTTCAACTGCCAATGGGCCAACGACATCGTTACCCGCAGCACCTGCAAGCAATATACCGGTCTCTCCGACAAGCCGCGA
CGCACAGTAGAGGTGACACC

Downstream 100 bases:

>100_bases
CGCACAGGAATTTTTCCTTATAAAAACAGGTAATACCCTAAATAATTTGAGTGCAGCAAGCCACCACCGGCCACTTTAAA
TATGACGGGTATCCAGGGCG

Product: chemotaxis protein CheA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 727; Mature: 726

Protein sequence:

>727_residues
MSMDITAFYQTFFDEADELLADMEQHLLLLDPLTPDNEQLNAIFRAAHSIKGGAATFGFTVLQETTHLLENLLDGARRDE
MRLSTEIINLFLETKDIMQEQLDAYKTSQEPHSESFEYICQALRQLALDALDQPTTEDQPTTENQSATDQHSTAANTQAT
ASTRVSSSLAGNTSPALLQGGMRIRLSGLKAPEISLMLEELGNLGEVQDPHQGADSLEATLITSVSEEDISAVLCFVLEP
EQISFVSAGDTEQIYAEQTVESEQSSEPERLFEPAITEASVIAESVQPVATPAATPAATPAVEVQSTLKADVHAAPANAE
QVRPKAKASESTSIRVAVEKVDQLINLVGELVITQSMLAQRSGSLDPVINGDLLNSMGQLERNARDLQESVMSIRMMPME
YVFSRFPRLVRDLASKLNKQVELTLLGSSTELDKSLIERIIDPLTHLVRNSLDHGIEEPATRIAAGKSPVGNLTLSAEHQ
GGNICIEVIDDGAGLNRQRILAKAQSQGLAVNENMSDEDVGMLIFAPGFSTAEQVTDVSGRGVGMDVVKRNIQEMGGHVQ
VSFQAGLGTSIRILLPLTLAILDGMSVKVSNEVFILPLNAVMESLQPLAEDLHPLAGGERVLQVRGEFLPLVELYRVFDV
KNAKTEATQGIVVILQSAGRRYALLVDQLIGQHQVVVKNLESNYRKVPGISAATILGDGSVALIVDVSALQALNREKRVA
ADEVVTA

Sequences:

>Translated_727_residues
MSMDITAFYQTFFDEADELLADMEQHLLLLDPLTPDNEQLNAIFRAAHSIKGGAATFGFTVLQETTHLLENLLDGARRDE
MRLSTEIINLFLETKDIMQEQLDAYKTSQEPHSESFEYICQALRQLALDALDQPTTEDQPTTENQSATDQHSTAANTQAT
ASTRVSSSLAGNTSPALLQGGMRIRLSGLKAPEISLMLEELGNLGEVQDPHQGADSLEATLITSVSEEDISAVLCFVLEP
EQISFVSAGDTEQIYAEQTVESEQSSEPERLFEPAITEASVIAESVQPVATPAATPAATPAVEVQSTLKADVHAAPANAE
QVRPKAKASESTSIRVAVEKVDQLINLVGELVITQSMLAQRSGSLDPVINGDLLNSMGQLERNARDLQESVMSIRMMPME
YVFSRFPRLVRDLASKLNKQVELTLLGSSTELDKSLIERIIDPLTHLVRNSLDHGIEEPATRIAAGKSPVGNLTLSAEHQ
GGNICIEVIDDGAGLNRQRILAKAQSQGLAVNENMSDEDVGMLIFAPGFSTAEQVTDVSGRGVGMDVVKRNIQEMGGHVQ
VSFQAGLGTSIRILLPLTLAILDGMSVKVSNEVFILPLNAVMESLQPLAEDLHPLAGGERVLQVRGEFLPLVELYRVFDV
KNAKTEATQGIVVILQSAGRRYALLVDQLIGQHQVVVKNLESNYRKVPGISAATILGDGSVALIVDVSALQALNREKRVA
ADEVVTA
>Mature_726_residues
SMDITAFYQTFFDEADELLADMEQHLLLLDPLTPDNEQLNAIFRAAHSIKGGAATFGFTVLQETTHLLENLLDGARRDEM
RLSTEIINLFLETKDIMQEQLDAYKTSQEPHSESFEYICQALRQLALDALDQPTTEDQPTTENQSATDQHSTAANTQATA
STRVSSSLAGNTSPALLQGGMRIRLSGLKAPEISLMLEELGNLGEVQDPHQGADSLEATLITSVSEEDISAVLCFVLEPE
QISFVSAGDTEQIYAEQTVESEQSSEPERLFEPAITEASVIAESVQPVATPAATPAATPAVEVQSTLKADVHAAPANAEQ
VRPKAKASESTSIRVAVEKVDQLINLVGELVITQSMLAQRSGSLDPVINGDLLNSMGQLERNARDLQESVMSIRMMPMEY
VFSRFPRLVRDLASKLNKQVELTLLGSSTELDKSLIERIIDPLTHLVRNSLDHGIEEPATRIAAGKSPVGNLTLSAEHQG
GNICIEVIDDGAGLNRQRILAKAQSQGLAVNENMSDEDVGMLIFAPGFSTAEQVTDVSGRGVGMDVVKRNIQEMGGHVQV
SFQAGLGTSIRILLPLTLAILDGMSVKVSNEVFILPLNAVMESLQPLAEDLHPLAGGERVLQVRGEFLPLVELYRVFDVK
NAKTEATQGIVVILQSAGRRYALLVDQLIGQHQVVVKNLESNYRKVPGISAATILGDGSVALIVDVSALQALNREKRVAA
DEVVTA

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=720, Percent_Identity=70, Blast_Score=956, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR015162
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01584 CheW; PF09078 CheY-binding; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 78608; Mature: 78477

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS00039 DEAD_ATP_HELICASE ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMDITAFYQTFFDEADELLADMEQHLLLLDPLTPDNEQLNAIFRAAHSIKGGAATFGFT
CCCCHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHH
VLQETTHLLENLLDGARRDEMRLSTEIINLFLETKDIMQEQLDAYKTSQEPHSESFEYIC
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
QALRQLALDALDQPTTEDQPTTENQSATDQHSTAANTQATASTRVSSSLAGNTSPALLQG
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHC
GMRIRLSGLKAPEISLMLEELGNLGEVQDPHQGADSLEATLITSVSEEDISAVLCFVLEP
CCEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHEEHEEECC
EQISFVSAGDTEQIYAEQTVESEQSSEPERLFEPAITEASVIAESVQPVATPAATPAATP
CCEEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
AVEVQSTLKADVHAAPANAEQVRPKAKASESTSIRVAVEKVDQLINLVGELVITQSMLAQ
HHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHH
RSGSLDPVINGDLLNSMGQLERNARDLQESVMSIRMMPMEYVFSRFPRLVRDLASKLNKQ
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCE
VELTLLGSSTELDKSLIERIIDPLTHLVRNSLDHGIEEPATRIAAGKSPVGNLTLSAEHQ
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEEEEECC
GGNICIEVIDDGAGLNRQRILAKAQSQGLAVNENMSDEDVGMLIFAPGFSTAEQVTDVSG
CCCEEEEEEECCCCCCHHHHHHHHHHCCEEECCCCCCCCCCEEEEECCCCCHHHHHCCCC
RGVGMDVVKRNIQEMGGHVQVSFQAGLGTSIRILLPLTLAILDGMSVKVSNEVFILPLNA
CCCCHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCEEEECCCEEEEEHHH
VMESLQPLAEDLHPLAGGERVLQVRGEFLPLVELYRVFDVKNAKTEATQGIVVILQSAGR
HHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHCCCEEEEECCCC
RYALLVDQLIGQHQVVVKNLESNYRKVPGISAATILGDGSVALIVDVSALQALNREKRVA
CHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEEHHHHHHHCHHHHHH
ADEVVTA
HHHHHCC
>Mature Secondary Structure 
SMDITAFYQTFFDEADELLADMEQHLLLLDPLTPDNEQLNAIFRAAHSIKGGAATFGFT
CCCHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHH
VLQETTHLLENLLDGARRDEMRLSTEIINLFLETKDIMQEQLDAYKTSQEPHSESFEYIC
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
QALRQLALDALDQPTTEDQPTTENQSATDQHSTAANTQATASTRVSSSLAGNTSPALLQG
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHC
GMRIRLSGLKAPEISLMLEELGNLGEVQDPHQGADSLEATLITSVSEEDISAVLCFVLEP
CCEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHEEHEEECC
EQISFVSAGDTEQIYAEQTVESEQSSEPERLFEPAITEASVIAESVQPVATPAATPAATP
CCEEEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
AVEVQSTLKADVHAAPANAEQVRPKAKASESTSIRVAVEKVDQLINLVGELVITQSMLAQ
HHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHH
RSGSLDPVINGDLLNSMGQLERNARDLQESVMSIRMMPMEYVFSRFPRLVRDLASKLNKQ
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCE
VELTLLGSSTELDKSLIERIIDPLTHLVRNSLDHGIEEPATRIAAGKSPVGNLTLSAEHQ
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEEEEECC
GGNICIEVIDDGAGLNRQRILAKAQSQGLAVNENMSDEDVGMLIFAPGFSTAEQVTDVSG
CCCEEEEEEECCCCCCHHHHHHHHHHCCEEECCCCCCCCCCEEEEECCCCCHHHHHCCCC
RGVGMDVVKRNIQEMGGHVQVSFQAGLGTSIRILLPLTLAILDGMSVKVSNEVFILPLNA
CCCCHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCEEEECCCEEEEEHHH
VMESLQPLAEDLHPLAGGERVLQVRGEFLPLVELYRVFDVKNAKTEATQGIVVILQSAGR
HHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHCCCEEEEECCCC
RYALLVDQLIGQHQVVVKNLESNYRKVPGISAATILGDGSVALIVDVSALQALNREKRVA
CHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEEHHHHHHHCHHHHHH
ADEVVTA
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3278311; 11677609 [H]