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The map label for this gene is tadA [H]

Identifier: 170023497

GI number: 170023497

Start: 1375423

End: 1375986

Strand: Direct

Name: tadA [H]

Synonym: YPK_1251

Alternate gene names: 170023497

Gene position: 1375423-1375986 (Clockwise)

Preceding gene: 170023496

Following gene: 170023499

Centisome position: 29.33

GC content: 54.26

Gene sequence:

>564_bases
GTGTCTGCTGATAATAGTTTGCCTGCTGATAATGGCTTGTCTTCTGAATGTGATTCTCCTGCTGAATACAGCGATGAGTA
CTGGATGCGCCATGCCTTAACGCTGGCGCTGCGAGCGCAGGAAGAGGGTGAAGTTCCGGTGGGGGCAGTGCTGGTCTTGG
GGAATAAGGTGATTGGTGAAGGGTGGAACCGGCCAATTCGCGATAATGACCCAACTGCTCATGCGGAAATTATGGCGCTA
CGCCAAGGTGGGCAGGCGGTACAGAATTATCGCCTGTTGGATGCCACCTTATATGTGACGCTGGAACCTTGCGTGATGTG
CGCCGGAGCCATGGTACACAGCCGGATCCGCCGGTTGGTTTATGGCGCAAATGATGTAAAAACCGGCGCCGCGGGGTCGC
TGGTAGATATTTTGCGCCACCCTGGGATGAACCACCAAATAGAGGTCAGTGCTGGCATACTGGCGACTGCGTGTTCCCAT
CAATTGAGTGCGTTCTTTCGCCAACGCCGTGAGCAGCAGAAAGCATTGAAACAAGCACCGCGGGCAGCAGAAGGTAAATT
CTGA

Upstream 100 bases:

>100_bases
TTAGCCACTAGCCAAAGCACCCCCCTGTTTTGCGACAAACTAACCGACTCGCCAGCAAGCTGTGTATAATGCCCGCCGCA
AAAGTGCCAGAGAGGTTAAT

Downstream 100 bases:

>100_bases
CGGCGGCCAGGTGATGCGCCGCCCAGCATGTTATGACGGGCGGCGGTTGGTGACTAAATCACGGTGTAATTAAGGTTGAA
CGACTGCCGACGAGTGACTG

Product: tRNA-specific adenosine deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MSADNSLPADNGLSSECDSPAEYSDEYWMRHALTLALRAQEEGEVPVGAVLVLGNKVIGEGWNRPIRDNDPTAHAEIMAL
RQGGQAVQNYRLLDATLYVTLEPCVMCAGAMVHSRIRRLVYGANDVKTGAAGSLVDILRHPGMNHQIEVSAGILATACSH
QLSAFFRQRREQQKALKQAPRAAEGKF

Sequences:

>Translated_187_residues
MSADNSLPADNGLSSECDSPAEYSDEYWMRHALTLALRAQEEGEVPVGAVLVLGNKVIGEGWNRPIRDNDPTAHAEIMAL
RQGGQAVQNYRLLDATLYVTLEPCVMCAGAMVHSRIRRLVYGANDVKTGAAGSLVDILRHPGMNHQIEVSAGILATACSH
QLSAFFRQRREQQKALKQAPRAAEGKF
>Mature_186_residues
SADNSLPADNGLSSECDSPAEYSDEYWMRHALTLALRAQEEGEVPVGAVLVLGNKVIGEGWNRPIRDNDPTAHAEIMALR
QGGQAVQNYRLLDATLYVTLEPCVMCAGAMVHSRIRRLVYGANDVKTGAAGSLVDILRHPGMNHQIEVSAGILATACSHQ
LSAFFRQRREQQKALKQAPRAAEGKF

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=180, Percent_Identity=33.3333333333333, Blast_Score=90, Evalue=1e-18,
Organism=Escherichia coli, GI145693172, Length=161, Percent_Identity=72.6708074534162, Blast_Score=248, Evalue=2e-67,
Organism=Escherichia coli, GI1786616, Length=154, Percent_Identity=31.8181818181818, Blast_Score=60, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17541138, Length=164, Percent_Identity=34.7560975609756, Blast_Score=94, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17554608, Length=97, Percent_Identity=42.2680412371134, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21355527, Length=146, Percent_Identity=32.1917808219178, Blast_Score=77, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 20369; Mature: 20238

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSADNSLPADNGLSSECDSPAEYSDEYWMRHALTLALRAQEEGEVPVGAVLVLGNKVIGE
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCHHHCC
GWNRPIRDNDPTAHAEIMALRQGGQAVQNYRLLDATLYVTLEPCVMCAGAMVHSRIRRLV
CCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHEEEEEEEHHHHHHHHHHHHHHHHHHH
YGANDVKTGAAGSLVDILRHPGMNHQIEVSAGILATACSHQLSAFFRQRREQQKALKQAP
HCCCCCCCCCCHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RAAEGKF
CCCCCCC
>Mature Secondary Structure 
SADNSLPADNGLSSECDSPAEYSDEYWMRHALTLALRAQEEGEVPVGAVLVLGNKVIGE
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCHHHCC
GWNRPIRDNDPTAHAEIMALRQGGQAVQNYRLLDATLYVTLEPCVMCAGAMVHSRIRRLV
CCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHEEEEEEEHHHHHHHHHHHHHHHHHHH
YGANDVKTGAAGSLVDILRHPGMNHQIEVSAGILATACSHQLSAFFRQRREQQKALKQAP
HCCCCCCCCCCHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RAAEGKF
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]