Click here to switch to the map view.

The map label for this gene is gsiC [H]

Identifier: 170023372

GI number: 170023372

Start: 1265797

End: 1266765

Strand: Direct

Name: gsiC [H]

Synonym: YPK_1126

Alternate gene names: 170023372

Gene position: 1265797-1266765 (Clockwise)

Preceding gene: 170023371

Following gene: 170023373

Centisome position: 26.99

GC content: 51.08

Gene sequence:

>969_bases
ATGAAGGGGATCTCGCTGTTTACTCTGCGCTTAATTTGCCTGCTGCTGGTCACCGCAGCCGGTACTTTTACATTGCTGAG
TTTTTCCCCTGTTGACCCTATACGTGCCTATATTGGTAGCGATTTACTGCATGTGCCGCCAGAGCAATACCCACTGATTG
CGGCTCGTTGGGGGCTGGATTTACCTTTGTGGCAACGTTTTTTGCATTGGTTTACTCAAGTGCTCCAAGGGGATTTTGGT
TACTCGATGCTGTATAACGCGCCGGTTTCTCAGGTGATAGGTGAGCGTTTTGCTACCTCGTTTGCGTTATTGGTCTCGGC
CTGGCTATTTTCGGGAATTGTCGGGTTGCTATTGGGGTTGACCGCTGGGCGCTATCTCAACCGTTGGCCTGATCGTCTGA
TTTCAACGTTGTCCTATTTATTGGCATCGTTGCCCACCTTTTGGATCGGTCTATTGTTGTTGTCGTTATTTGCGGTGAAG
CTCAATTGGGCCCCCATTTGCTGTGCATGGACGCCAGGGAGTCAGGCCGAGACCGCCAGTTGGGGGGATAAGCTTCACCA
CCTGATTTTACCGATGCTAGCGCTGGGGTTACTGGGGGTTGGGAACATTGCACTGCATACCCGTGCCAGAGTTGCTGAAG
TGATGAATAGCGAATTTATTCGCTATGCACAAGCACAGGGGGATAAAGGCTGGCCTTTGGTGAACTTCCATATTTTACGC
CATGCCATTACACCCGCGCTTTGCCTGCAATTCGCTTCAGTTGGCGAATTACTGGGGGGGTCTTTATTGGCCGAAAAAGT
GTTCGCCTATCCCGGTTTGGGGCAGGCGACGATTGATGCCGGGTTGCATGGTGACATTCCACTCTTGATGGGAATAGTGA
TGTTCTGCGCCATATTGGTCTTTTGCGGTAATAGCATTGCGAATGCCTTGTTACACCGTTTGAACCGGGGGGCTGCGCGG
CAATTATGA

Upstream 100 bases:

>100_bases
TGGCCAATAACTGCGTTGATTTAGGTAAAGGAACACCGGAAATTCACGGCTCCTGGTCATTGCTCAATAGTATTGATAGC
TGGAAATGGACCTGTCAGTA

Downstream 100 bases:

>100_bases
CTTATAACCCAAACCGGGCCTTGTTCCGGCTGTTCGTCTCACTGGTCTTATTATCTATTTTAATCGTTTATGGTTGGCTA
ATTTATGGCGCTGAAGTTCC

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MKGISLFTLRLICLLLVTAAGTFTLLSFSPVDPIRAYIGSDLLHVPPEQYPLIAARWGLDLPLWQRFLHWFTQVLQGDFG
YSMLYNAPVSQVIGERFATSFALLVSAWLFSGIVGLLLGLTAGRYLNRWPDRLISTLSYLLASLPTFWIGLLLLSLFAVK
LNWAPICCAWTPGSQAETASWGDKLHHLILPMLALGLLGVGNIALHTRARVAEVMNSEFIRYAQAQGDKGWPLVNFHILR
HAITPALCLQFASVGELLGGSLLAEKVFAYPGLGQATIDAGLHGDIPLLMGIVMFCAILVFCGNSIANALLHRLNRGAAR
QL

Sequences:

>Translated_322_residues
MKGISLFTLRLICLLLVTAAGTFTLLSFSPVDPIRAYIGSDLLHVPPEQYPLIAARWGLDLPLWQRFLHWFTQVLQGDFG
YSMLYNAPVSQVIGERFATSFALLVSAWLFSGIVGLLLGLTAGRYLNRWPDRLISTLSYLLASLPTFWIGLLLLSLFAVK
LNWAPICCAWTPGSQAETASWGDKLHHLILPMLALGLLGVGNIALHTRARVAEVMNSEFIRYAQAQGDKGWPLVNFHILR
HAITPALCLQFASVGELLGGSLLAEKVFAYPGLGQATIDAGLHGDIPLLMGIVMFCAILVFCGNSIANALLHRLNRGAAR
QL
>Mature_322_residues
MKGISLFTLRLICLLLVTAAGTFTLLSFSPVDPIRAYIGSDLLHVPPEQYPLIAARWGLDLPLWQRFLHWFTQVLQGDFG
YSMLYNAPVSQVIGERFATSFALLVSAWLFSGIVGLLLGLTAGRYLNRWPDRLISTLSYLLASLPTFWIGLLLLSLFAVK
LNWAPICCAWTPGSQAETASWGDKLHHLILPMLALGLLGVGNIALHTRARVAEVMNSEFIRYAQAQGDKGWPLVNFHILR
HAITPALCLQFASVGELLGGSLLAEKVFAYPGLGQATIDAGLHGDIPLLMGIVMFCAILVFCGNSIANALLHRLNRGAAR
QL

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=307, Percent_Identity=31.9218241042345, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1789965, Length=331, Percent_Identity=31.1178247734139, Blast_Score=148, Evalue=5e-37,
Organism=Escherichia coli, GI1787497, Length=307, Percent_Identity=29.6416938110749, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1787550, Length=269, Percent_Identity=27.8810408921933, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1789888, Length=302, Percent_Identity=26.4900662251656, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1787761, Length=292, Percent_Identity=28.7671232876712, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1788504, Length=267, Percent_Identity=22.8464419475655, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 35234; Mature: 35234

Theoretical pI: Translated: 8.59; Mature: 8.59

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGISLFTLRLICLLLVTAAGTFTLLSFSPVDPIRAYIGSDLLHVPPEQYPLIAARWGLD
CCCHHHHHHHHHHHHHHHHCCHHHEEECCCCHHHHHHHCCCCCCCCCCCCCEEHHHCCCC
LPLWQRFLHWFTQVLQGDFGYSMLYNAPVSQVIGERFATSFALLVSAWLFSGIVGLLLGL
CHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAGRYLNRWPDRLISTLSYLLASLPTFWIGLLLLSLFAVKLNWAPICCAWTPGSQAETAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHH
WGDKLHHLILPMLALGLLGVGNIALHTRARVAEVMNSEFIRYAQAQGDKGWPLVNFHILR
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
HAITPALCLQFASVGELLGGSLLAEKVFAYPGLGQATIDAGLHGDIPLLMGIVMFCAILV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHH
FCGNSIANALLHRLNRGAARQL
HHCHHHHHHHHHHHCCHHHCCC
>Mature Secondary Structure
MKGISLFTLRLICLLLVTAAGTFTLLSFSPVDPIRAYIGSDLLHVPPEQYPLIAARWGLD
CCCHHHHHHHHHHHHHHHHCCHHHEEECCCCHHHHHHHCCCCCCCCCCCCCEEHHHCCCC
LPLWQRFLHWFTQVLQGDFGYSMLYNAPVSQVIGERFATSFALLVSAWLFSGIVGLLLGL
CHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAGRYLNRWPDRLISTLSYLLASLPTFWIGLLLLSLFAVKLNWAPICCAWTPGSQAETAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHH
WGDKLHHLILPMLALGLLGVGNIALHTRARVAEVMNSEFIRYAQAQGDKGWPLVNFHILR
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
HAITPALCLQFASVGELLGGSLLAEKVFAYPGLGQATIDAGLHGDIPLLMGIVMFCAILV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHH
FCGNSIANALLHRLNRGAARQL
HHCHHHHHHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA