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The map label for this gene is ltrA [H]

Identifier: 170023270

GI number: 170023270

Start: 1145648

End: 1146556

Strand: Direct

Name: ltrA [H]

Synonym: YPK_1021

Alternate gene names: 170023270

Gene position: 1145648-1146556 (Clockwise)

Preceding gene: 170023267

Following gene: 170023271

Centisome position: 24.43

GC content: 49.83

Gene sequence:

>909_bases
ATGGATAGAATCACTGCAGCAGAGGTTTTTGTCGCGATTGTGGATCGGGGGAGTATGATTGCCGCCGCAGAGTCACTGGA
GATGTCCAGGGCAATGGCGACACGCTATCTGGCTCAGATGGAGCAATGGGCGGGGGCGCGCTTATTGCATCGGACCACCC
GTAAATTGAGCCTGACACATGCCGGTGAGGCGACGCTCGAGCGCTGTCGACGTATGCTTGAGTTTGCTCAGGATATGGAT
CTGGCTGAGGGGCAGGAAAGTGAAGAGTTACGCGGTTTGCTACGTATCAGTTGCTCGCAATCTCTTGGGCAGAGTGCTCT
GGCTATTGCAGTTGCTGACTATCTACGCCGCTATCCACAGGTCGCTGTTGATTTACAGATGAATAACCGGGCGATCAATT
TAGTGGAAGAACGTATTGATCTGGCGCTACGGATTACCAATGAATTAGACCCCAACTTAATTGCTCGCCCTCTTTCAACG
TGTTATTCAGTCGTCTGTGCCTCACCCGCTTATTTATCTGTCAGCGGTATTCCCGAAAGCCCACAAGATTTAACGGTACA
CAACTGCCTGACGTACTCCTACTTCGGTGAGAGTTTATGGCATTTTGATCAGTCGGGCGTGAAATCATCGGTTGCCGTCA
GTGGCAATTTGAGTGCGAATGAATCGGTAGTTTTACTGAGTGGCGCTTTAGAAGGCGCGGGTATCACCTTGCAGCCGATC
TATTCTGTAGCGCCATATATTGCCCGTGGTGAGTTAATTAAGTTATTACCAGATTATCAACCGCAGGCCATGGGTATTTA
TGGGGTTTATGCTTCGCGCCGACAAATGCCAACCACATTAAGAACGATGCTCGACTTTCTGGTTGAGTGGTTTGCCACAT
ATCCTCAGTGGTTATCGACAATGAAGTGA

Upstream 100 bases:

>100_bases
TGTCCTATTGACCGTGGGGTAGGTGATAGATAATAGATTGCATATATCGATAGAAAAACCCGATAATGAGCAATTATTTG
TTGCATAAATCGAGCGAATC

Downstream 100 bases:

>100_bases
GGTGCTGTCGATATGAGGTGTTATCGATAAGAGAGTGAACCGTTTTATGACATCGTCAAACCTATTTTTATTATCAGCGA
TTGCATAGCGTTATTGAATA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MDRITAAEVFVAIVDRGSMIAAAESLEMSRAMATRYLAQMEQWAGARLLHRTTRKLSLTHAGEATLERCRRMLEFAQDMD
LAEGQESEELRGLLRISCSQSLGQSALAIAVADYLRRYPQVAVDLQMNNRAINLVEERIDLALRITNELDPNLIARPLST
CYSVVCASPAYLSVSGIPESPQDLTVHNCLTYSYFGESLWHFDQSGVKSSVAVSGNLSANESVVLLSGALEGAGITLQPI
YSVAPYIARGELIKLLPDYQPQAMGIYGVYASRRQMPTTLRTMLDFLVEWFATYPQWLSTMK

Sequences:

>Translated_302_residues
MDRITAAEVFVAIVDRGSMIAAAESLEMSRAMATRYLAQMEQWAGARLLHRTTRKLSLTHAGEATLERCRRMLEFAQDMD
LAEGQESEELRGLLRISCSQSLGQSALAIAVADYLRRYPQVAVDLQMNNRAINLVEERIDLALRITNELDPNLIARPLST
CYSVVCASPAYLSVSGIPESPQDLTVHNCLTYSYFGESLWHFDQSGVKSSVAVSGNLSANESVVLLSGALEGAGITLQPI
YSVAPYIARGELIKLLPDYQPQAMGIYGVYASRRQMPTTLRTMLDFLVEWFATYPQWLSTMK
>Mature_302_residues
MDRITAAEVFVAIVDRGSMIAAAESLEMSRAMATRYLAQMEQWAGARLLHRTTRKLSLTHAGEATLERCRRMLEFAQDMD
LAEGQESEELRGLLRISCSQSLGQSALAIAVADYLRRYPQVAVDLQMNNRAINLVEERIDLALRITNELDPNLIARPLST
CYSVVCASPAYLSVSGIPESPQDLTVHNCLTYSYFGESLWHFDQSGVKSSVAVSGNLSANESVVLLSGALEGAGITLQPI
YSVAPYIARGELIKLLPDYQPQAMGIYGVYASRRQMPTTLRTMLDFLVEWFATYPQWLSTMK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789440, Length=285, Percent_Identity=33.6842105263158, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI87081978, Length=301, Percent_Identity=33.8870431893688, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1789639, Length=302, Percent_Identity=31.7880794701987, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI1786401, Length=292, Percent_Identity=35.6164383561644, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI145693193, Length=295, Percent_Identity=28.4745762711864, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1787128, Length=286, Percent_Identity=27.6223776223776, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1787589, Length=286, Percent_Identity=26.9230769230769, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788706, Length=263, Percent_Identity=23.1939163498099, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1790011, Length=286, Percent_Identity=23.7762237762238, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33498; Mature: 33498

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRITAAEVFVAIVDRGSMIAAAESLEMSRAMATRYLAQMEQWAGARLLHRTTRKLSLTH
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECC
AGEATLERCRRMLEFAQDMDLAEGQESEELRGLLRISCSQSLGQSALAIAVADYLRRYPQ
CCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCC
VAVDLQMNNRAINLVEERIDLALRITNELDPNLIARPLSTCYSVVCASPAYLSVSGIPES
EEEEEEECCHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCC
PQDLTVHNCLTYSYFGESLWHFDQSGVKSSVAVSGNLSANESVVLLSGALEGAGITLQPI
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCEEEEECCCCCCCEEEHHH
YSVAPYIARGELIKLLPDYQPQAMGIYGVYASRRQMPTTLRTMLDFLVEWFATYPQWLST
HHHCCHHHCCHHHEECCCCCCCCEEEEEEHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
MK
CC
>Mature Secondary Structure
MDRITAAEVFVAIVDRGSMIAAAESLEMSRAMATRYLAQMEQWAGARLLHRTTRKLSLTH
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECC
AGEATLERCRRMLEFAQDMDLAEGQESEELRGLLRISCSQSLGQSALAIAVADYLRRYPQ
CCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCC
VAVDLQMNNRAINLVEERIDLALRITNELDPNLIARPLSTCYSVVCASPAYLSVSGIPES
EEEEEEECCHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCC
PQDLTVHNCLTYSYFGESLWHFDQSGVKSSVAVSGNLSANESVVLLSGALEGAGITLQPI
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCEEEEECCCCCCCEEEHHH
YSVAPYIARGELIKLLPDYQPQAMGIYGVYASRRQMPTTLRTMLDFLVEWFATYPQWLST
HHHCCHHHCCHHHEECCCCCCCCEEEEEEHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
MK
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8748036 [H]