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The map label for this gene is agaS [H]

Identifier: 170023242

GI number: 170023242

Start: 1114020

End: 1115186

Strand: Reverse

Name: agaS [H]

Synonym: YPK_0993

Alternate gene names: 170023242

Gene position: 1115186-1114020 (Counterclockwise)

Preceding gene: 170023243

Following gene: 170023241

Centisome position: 23.78

GC content: 47.39

Gene sequence:

>1167_bases
ATGACGCAATATTTAGGGTACAGCCGGGAAGAACTGACTCGCTTACATGCCAGTTGGACCGCACAGGAAATTGAACAACA
GCCTGCATGTTGGGGAAAAACACAGCGTATTGTGGAAGAGAGTCAGGCAGCGATTAATGATTTTCTGCATCAGGCATTAG
CCGCGAGTAACACGCGGATTATTTTTACCGGTGCTGGAACCTCAGCCTTTGCCGGGCGGGCGCTGGCTCCGCTGTTAGCA
CCTTATCTGTCCCATCGGATTGAAGCGATTGCGACAACGGATTTGGTGGCAACACCAGAACAATATTTCTCCGAAGATAT
TCCGACGCTGCTGGTTTCATTTGCCCGTTCCGGCAACAGCCCGGAAAGTGTGGCTGCGTTACAAGTGGCATCGGCCTGTT
TATCTCGCTGTTTCCACTTGGTATTGACCTGTAACCAGGGCGGCCAGTTATATCAATATTGCCAGACGGCACCAGGTGCA
TTGGCCGTGCTGATGCCAGCAGAAACCAATGACCAATCACTGGCGATGACCTCCAGTTTCTCCTCCATGATGATGGCTGC
GATGGCTATTTTTGCTGGGATTGATAAGTATTCGAAAGAAATTGAAAGATTTTGTAAGGGATCTGCGGATTGGTTCAAAG
AAATTAATCATAAAATCATCGATAATACTAAAAGTTCGCAATACCAAAGGGTTATCTACTTAGGTAGTGGCGGACTACAG
GGGCTGGCCCAAGAGTCAGCACTGAAATTACTCGAATTAACCGCAGGTAAAGTTGTGGCTACTTTTGATACTCCGTTGGG
ATTCCGCCATGGTCCGAAATCAATCGTTAATCCGGACACTTTGGTTGTTGTTTACATCTCTAATGATCCCTACACGCGTC
AATATGATCTCGACCTGTTAGCTGAGATCCGCGCCAACAACGTTGCCGGTAAGGTTATCGCTATCGCAGCACAATCAGAT
GCTTATGTCACAGCTGGTGACCATGTTCTGGTACCTGGTATGGCAGAAAGTTCTGACTTAGGCCTGCTGTTTGCCTATCT
GATGTTTGCACAATCCTTCGCTTTTCATAGCTCAGTTGCCTTAAACAACACGCCGGATAGCCCATCTCCAACGGGTGAAA
TCAATCGCGTGGTGCAAGGTGTGACTATTTATCCATTTAAAAAATAA

Upstream 100 bases:

>100_bases
CTCTGTCTTTTGAAGCCACGGCATTGGTCAAACAACAAATCAAAAATACGCTTATTGGCTATGTCAATGCATGCCACCTT
TTTAACGGGAACACATCGAA

Downstream 100 bases:

>100_bases
CACACAGGAATATCCCTATGACTCGGCCAAATATCGTCTGGACTCGTATTGATGAGCGTTTACTTCATGGACAGATCCGC
ATTACCTGGGGAAAGCACAC

Product: AgaS family sugar isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MTQYLGYSREELTRLHASWTAQEIEQQPACWGKTQRIVEESQAAINDFLHQALAASNTRIIFTGAGTSAFAGRALAPLLA
PYLSHRIEAIATTDLVATPEQYFSEDIPTLLVSFARSGNSPESVAALQVASACLSRCFHLVLTCNQGGQLYQYCQTAPGA
LAVLMPAETNDQSLAMTSSFSSMMMAAMAIFAGIDKYSKEIERFCKGSADWFKEINHKIIDNTKSSQYQRVIYLGSGGLQ
GLAQESALKLLELTAGKVVATFDTPLGFRHGPKSIVNPDTLVVVYISNDPYTRQYDLDLLAEIRANNVAGKVIAIAAQSD
AYVTAGDHVLVPGMAESSDLGLLFAYLMFAQSFAFHSSVALNNTPDSPSPTGEINRVVQGVTIYPFKK

Sequences:

>Translated_388_residues
MTQYLGYSREELTRLHASWTAQEIEQQPACWGKTQRIVEESQAAINDFLHQALAASNTRIIFTGAGTSAFAGRALAPLLA
PYLSHRIEAIATTDLVATPEQYFSEDIPTLLVSFARSGNSPESVAALQVASACLSRCFHLVLTCNQGGQLYQYCQTAPGA
LAVLMPAETNDQSLAMTSSFSSMMMAAMAIFAGIDKYSKEIERFCKGSADWFKEINHKIIDNTKSSQYQRVIYLGSGGLQ
GLAQESALKLLELTAGKVVATFDTPLGFRHGPKSIVNPDTLVVVYISNDPYTRQYDLDLLAEIRANNVAGKVIAIAAQSD
AYVTAGDHVLVPGMAESSDLGLLFAYLMFAQSFAFHSSVALNNTPDSPSPTGEINRVVQGVTIYPFKK
>Mature_387_residues
TQYLGYSREELTRLHASWTAQEIEQQPACWGKTQRIVEESQAAINDFLHQALAASNTRIIFTGAGTSAFAGRALAPLLAP
YLSHRIEAIATTDLVATPEQYFSEDIPTLLVSFARSGNSPESVAALQVASACLSRCFHLVLTCNQGGQLYQYCQTAPGAL
AVLMPAETNDQSLAMTSSFSSMMMAAMAIFAGIDKYSKEIERFCKGSADWFKEINHKIIDNTKSSQYQRVIYLGSGGLQG
LAQESALKLLELTAGKVVATFDTPLGFRHGPKSIVNPDTLVVVYISNDPYTRQYDLDLLAEIRANNVAGKVIAIAAQSDA
YVTAGDHVLVPGMAESSDLGLLFAYLMFAQSFAFHSSVALNNTPDSPSPTGEINRVVQGVTIYPFKK

Specific function: May be a tagatose-6-phosphate ketose/aldose isomerase [H]

COG id: COG2222

COG function: function code M; Predicted phosphosugar isomerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Escherichia coli, GI1789525, Length=374, Percent_Identity=48.6631016042781, Blast_Score=361, Evalue=1e-101,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001347
- InterPro:   IPR014180 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: 5.-.-.- [C]

Molecular weight: Translated: 42048; Mature: 41917

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQYLGYSREELTRLHASWTAQEIEQQPACWGKTQRIVEESQAAINDFLHQALAASNTRI
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEE
IFTGAGTSAFAGRALAPLLAPYLSHRIEAIATTDLVATPEQYFSEDIPTLLVSFARSGNS
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCC
PESVAALQVASACLSRCFHLVLTCNQGGQLYQYCQTAPGALAVLMPAETNDQSLAMTSSF
HHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHCCCCEEEEEEECCCCCCCEEHHHHH
SSMMMAAMAIFAGIDKYSKEIERFCKGSADWFKEINHKIIDNTKSSQYQRVIYLGSGGLQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCC
GLAQESALKLLELTAGKVVATFDTPLGFRHGPKSIVNPDTLVVVYISNDPYTRQYDLDLL
HHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEECHHHH
AEIRANNVAGKVIAIAAQSDAYVTAGDHVLVPGMAESSDLGLLFAYLMFAQSFAFHSSVA
HHHHCCCCCCEEEEEEECCCCEEECCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCEE
LNNTPDSPSPTGEINRVVQGVTIYPFKK
ECCCCCCCCCCHHHHHHHCCCEEECCCC
>Mature Secondary Structure 
TQYLGYSREELTRLHASWTAQEIEQQPACWGKTQRIVEESQAAINDFLHQALAASNTRI
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEE
IFTGAGTSAFAGRALAPLLAPYLSHRIEAIATTDLVATPEQYFSEDIPTLLVSFARSGNS
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCC
PESVAALQVASACLSRCFHLVLTCNQGGQLYQYCQTAPGALAVLMPAETNDQSLAMTSSF
HHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHCCCCEEEEEEECCCCCCCEEHHHHH
SSMMMAAMAIFAGIDKYSKEIERFCKGSADWFKEINHKIIDNTKSSQYQRVIYLGSGGLQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCC
GLAQESALKLLELTAGKVVATFDTPLGFRHGPKSIVNPDTLVVVYISNDPYTRQYDLDLL
HHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEECHHHH
AEIRANNVAGKVIAIAAQSDAYVTAGDHVLVPGMAESSDLGLLFAYLMFAQSFAFHSSVA
HHHHCCCCCCEEEEEEECCCCEEECCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCEE
LNNTPDSPSPTGEINRVVQGVTIYPFKK
ECCCCCCCCCCHHHHHHHCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503; 8932697 [H]