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The map label for this gene is yadA [H]

Identifier: 170023120

GI number: 170023120

Start: 997332

End: 999482

Strand: Direct

Name: yadA [H]

Synonym: YPK_0871

Alternate gene names: 170023120

Gene position: 997332-999482 (Clockwise)

Preceding gene: 170023119

Following gene: 170023121

Centisome position: 21.27

GC content: 52.16

Gene sequence:

>2151_bases
ATGGAAAACATCATAAAATATGACATTAATTATTTTTTAAGGTTTGTTTGTTTTAATTACTTTATGAACATAAAGTTTTA
TCGTGGTCTGTTTAGTATTTCTATAGTGATGATTTATTTATTTATCCCTGGCACCGCAACTTCTCAGCTTTATGTGAATA
ATGCTGATGATCAGTCTTGTTATGCCATTATGGATGGGCCGTCGGTGGGGCCTATAACTAGTCCGAATTGTAATACTCCA
TCTATTGGGATTATTAATACAAATGCGGGGCAGCTATTTGTTGGTGGAACGGGGGCTGCGGTATCGGGAACATTAGGCCC
TACTTTTTGGACAGGGACATTTGCTACACCGGTCGGCACCAGTAATACCGCAACTGCATACGGTATGGTCGTTCAAAGCG
GTGGTGCGTACATCACGGGTAATACTTACGTACAAGGTGGGTTATTCTTGAATGGGCAAAAAGCGACCAATCTTGCCCCT
GCGACGATTTCATCTACCTCTACCGATGCGGTAGTTGGTAGCCAGCTTTATAATCTGGTCCAAGATGGAACCCGCTATTT
CCATGCTAACTCAGTGAATCCAACAGACTCACTGGCCTCTGGCCTGGAAACCATTGCTGTCGGGCCAGCGACAGTGGTCA
GTGGAGATAACGGTGTTGGCATTGGTAACACCGCCCTTGTCGGAACGGCAGCAACGGGGGGAATTGCAATAGGTTTCGGT
ACTCAGGTGATAGCTGCCGGGGCTACGGCCATCGGTTCCGCAGCGCAGGCTCAAGGGGCACAATCTCTGGCGTTAGGCGC
GGGGGCGGTGACCAGCCAGGCAAACAGTATCGCGTTGGGGGCTGCTTCGATCAATACGGTCGGCGCTCAGAGCAGTTACA
GTGCTTATGCACTAACGGCTCCGCAGGTATCGGTGGGGGAGTTAGGGATTGGCACCGCATTGGGTAATCGTAAGATTACC
GGTGTCGCAGCTGGATCGGCGAGTTCTGATGCGGTCAATGTTGCTCAGTTGACTGCTGTTGGTGATCAGGTGCAGCAGAA
TACCGCGAACATCACCAGCCTGGGTGGCCGGGTTACCACCATTGAGGGGAGCATGGCCAGCATCGCCAATGGTGGCGGTG
TGAAGTATTTCCATGCCAACTCGACTCAGCCTGACTCGGTAGCCAGTGGTACCCATTCGGTGGCCATCGGGCCTGCTTCT
CTGGCCTCTGGGGCTGCTTCTCTGGCTTCGGGTAATGCTGCTTTGGCTTCGGGGGCAGGGGCGGTGGCGATAGGGGATGG
TGCTGCCGCCAGCGCGGACGGCAGTGTTGCCATTGGTCAGGGATCTGGTGATAACGGGCGTGGCGTAGAGAACTACATCG
GTAAGTATTCCAATGCGAGTAACACCAGCTCGGGTACCGTATCAGTGGGTAATACTGCTACTGGAGAAACCCGGACGTTC
AGCAATGTTGCCGATGGGCTGCAGGCCACCGATGCGGTCAATTTGCGACAACTCGATGGTATTGCTGCCTCTATCGTCGT
CGTCGAAAACAACGTTTCTGGGCTCCAGAATGGTACCGATGGTATGTTTCAGGTGAATAATAGTAGCGGTCTTGCCAAGC
CATCCGCAACCGGTGCCAATTCAGCAACTGGTGGTGCCGGTTCTGTGGCTTCCGGCAATAACAGTACCGCGTTTGGCTCA
GGTGCTAAAGCAACAGCGGCAAACAGTGCAGCCTTGGGGGCTAACTCAGTAGCTGATCGGGCAAACAGTGTTTCGGTAGG
CTCTGTTGGTAATGAACGGCAGATCACCAACGTCGCCCCCGCAACTCAGGGAACCGACGCGGTGAACTTCGATCAACTTA
AGAGCATCTCCAATCAAACTAATGCTTACACGAACCAACGTTATTCCGAGCTGAAGCAGGATCTGAGGAAACAAAATAGC
GTGTTGAGTGCAGGGATAGCTAGCGCAATGTCTATGGCGAGCTTGACACAACCATATACTTCGGGTTCCAGCATGACCAC
TATCGGCGCGGCCAGTTACCGTGGTCAATCGGCTCTGTCGCTAGGGGTATCGAGTATTTCTGACAGCGGGAGATGGGGCA
GCAAACTACAGGCATCCTCTAACACTCAAGGTGATTTTGGGATTGGTGTCGGCGTAGGGTATCAGTGGTAA

Upstream 100 bases:

>100_bases
CTAAAAAGCATAAGATAATAAATTCACTTCAGGTTGTTACATCACTACCTACAAATTCTTCACCTGTAAAAAGGTGATAT
AAAATAAAGTGGAGAGTGGC

Downstream 100 bases:

>100_bases
AGAGCGCGTTACGCCAACGCTGAATGCTATTCAGGCTGTCACTAACGGGTTGTAGGGTGTTTTGTACAACCCGATTCTCG
CTCTTGGGCATCAAAGGATC

Product: YadA domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 716; Mature: 716

Protein sequence:

>716_residues
MENIIKYDINYFLRFVCFNYFMNIKFYRGLFSISIVMIYLFIPGTATSQLYVNNADDQSCYAIMDGPSVGPITSPNCNTP
SIGIINTNAGQLFVGGTGAAVSGTLGPTFWTGTFATPVGTSNTATAYGMVVQSGGAYITGNTYVQGGLFLNGQKATNLAP
ATISSTSTDAVVGSQLYNLVQDGTRYFHANSVNPTDSLASGLETIAVGPATVVSGDNGVGIGNTALVGTAATGGIAIGFG
TQVIAAGATAIGSAAQAQGAQSLALGAGAVTSQANSIALGAASINTVGAQSSYSAYALTAPQVSVGELGIGTALGNRKIT
GVAAGSASSDAVNVAQLTAVGDQVQQNTANITSLGGRVTTIEGSMASIANGGGVKYFHANSTQPDSVASGTHSVAIGPAS
LASGAASLASGNAALASGAGAVAIGDGAAASADGSVAIGQGSGDNGRGVENYIGKYSNASNTSSGTVSVGNTATGETRTF
SNVADGLQATDAVNLRQLDGIAASIVVVENNVSGLQNGTDGMFQVNNSSGLAKPSATGANSATGGAGSVASGNNSTAFGS
GAKATAANSAALGANSVADRANSVSVGSVGNERQITNVAPATQGTDAVNFDQLKSISNQTNAYTNQRYSELKQDLRKQNS
VLSAGIASAMSMASLTQPYTSGSSMTTIGAASYRGQSALSLGVSSISDSGRWGSKLQASSNTQGDFGIGVGVGYQW

Sequences:

>Translated_716_residues
MENIIKYDINYFLRFVCFNYFMNIKFYRGLFSISIVMIYLFIPGTATSQLYVNNADDQSCYAIMDGPSVGPITSPNCNTP
SIGIINTNAGQLFVGGTGAAVSGTLGPTFWTGTFATPVGTSNTATAYGMVVQSGGAYITGNTYVQGGLFLNGQKATNLAP
ATISSTSTDAVVGSQLYNLVQDGTRYFHANSVNPTDSLASGLETIAVGPATVVSGDNGVGIGNTALVGTAATGGIAIGFG
TQVIAAGATAIGSAAQAQGAQSLALGAGAVTSQANSIALGAASINTVGAQSSYSAYALTAPQVSVGELGIGTALGNRKIT
GVAAGSASSDAVNVAQLTAVGDQVQQNTANITSLGGRVTTIEGSMASIANGGGVKYFHANSTQPDSVASGTHSVAIGPAS
LASGAASLASGNAALASGAGAVAIGDGAAASADGSVAIGQGSGDNGRGVENYIGKYSNASNTSSGTVSVGNTATGETRTF
SNVADGLQATDAVNLRQLDGIAASIVVVENNVSGLQNGTDGMFQVNNSSGLAKPSATGANSATGGAGSVASGNNSTAFGS
GAKATAANSAALGANSVADRANSVSVGSVGNERQITNVAPATQGTDAVNFDQLKSISNQTNAYTNQRYSELKQDLRKQNS
VLSAGIASAMSMASLTQPYTSGSSMTTIGAASYRGQSALSLGVSSISDSGRWGSKLQASSNTQGDFGIGVGVGYQW
>Mature_716_residues
MENIIKYDINYFLRFVCFNYFMNIKFYRGLFSISIVMIYLFIPGTATSQLYVNNADDQSCYAIMDGPSVGPITSPNCNTP
SIGIINTNAGQLFVGGTGAAVSGTLGPTFWTGTFATPVGTSNTATAYGMVVQSGGAYITGNTYVQGGLFLNGQKATNLAP
ATISSTSTDAVVGSQLYNLVQDGTRYFHANSVNPTDSLASGLETIAVGPATVVSGDNGVGIGNTALVGTAATGGIAIGFG
TQVIAAGATAIGSAAQAQGAQSLALGAGAVTSQANSIALGAASINTVGAQSSYSAYALTAPQVSVGELGIGTALGNRKIT
GVAAGSASSDAVNVAQLTAVGDQVQQNTANITSLGGRVTTIEGSMASIANGGGVKYFHANSTQPDSVASGTHSVAIGPAS
LASGAASLASGNAALASGAGAVAIGDGAAASADGSVAIGQGSGDNGRGVENYIGKYSNASNTSSGTVSVGNTATGETRTF
SNVADGLQATDAVNLRQLDGIAASIVVVENNVSGLQNGTDGMFQVNNSSGLAKPSATGANSATGGAGSVASGNNSTAFGS
GAKATAANSAALGANSVADRANSVSVGSVGNERQITNVAPATQGTDAVNFDQLKSISNQTNAYTNQRYSELKQDLRKQNS
VLSAGIASAMSMASLTQPYTSGSSMTTIGAASYRGQSALSLGVSSISDSGRWGSKLQASSNTQGDFGIGVGVGYQW

Specific function: Collagen-binding outer membrane protein forming a fibrillar matrix on the bacterial cell surface. Promotes initial attachment and invasion of eukaryotic cells. Also protects the bacteria by being responsible for agglutination, serum resistance, complement

COG id: COG5295

COG function: function code UW; Autotransporter adhesin

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the autotransporter-2 (TC 1.B.40) / oligomeric coiled-coil adhesin (Oca) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008640
- InterPro:   IPR008635
- InterPro:   IPR008126
- InterPro:   IPR005594 [H]

Pfam domain/function: PF05658 Hep_Hag; PF05662 HIM; PF03895 YadA [H]

EC number: NA

Molecular weight: Translated: 70706; Mature: 70706

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENIIKYDINYFLRFVCFNYFMNIKFYRGLFSISIVMIYLFIPGTATSQLYVNNADDQSC
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCEEEEECCCCCCE
YAIMDGPSVGPITSPNCNTPSIGIINTNAGQLFVGGTGAAVSGTLGPTFWTGTFATPVGT
EEEECCCCCCCCCCCCCCCCEEEEEECCCCEEEECCCCCEEECCCCCCEECCCEECCCCC
SNTATAYGMVVQSGGAYITGNTYVQGGLFLNGQKATNLAPATISSTSTDAVVGSQLYNLV
CCCCEEEEEEEECCCCEEECCEEEECCEEECCCCCCCCCCCEECCCCCHHHHHHHHHHHH
QDGTRYFHANSVNPTDSLASGLETIAVGPATVVSGDNGVGIGNTALVGTAATGGIAIGFG
HCCCEEEECCCCCCHHHHHHCCCEEECCCEEEEECCCCCCCCCCEEEEECCCCCEEEECC
TQVIAAGATAIGSAAQAQGAQSLALGAGAVTSQANSIALGAASINTVGAQSSYSAYALTA
CCEECCCCHHHCCHHHHCCCCCEEECCCHHHCCCCEEEEECCCCCCCCCCCCCCEEEEEC
PQVSVGELGIGTALGNRKITGVAAGSASSDAVNVAQLTAVGDQVQQNTANITSLGGRVTT
CCCCCCCCCCEEECCCCEEEEEECCCCCCCCEEHHHHHHHHHHHHHCCCCHHHCCCEEEE
IEGSMASIANGGGVKYFHANSTQPDSVASGTHSVAIGPASLASGAASLASGNAALASGAG
ECCCHHHHCCCCCEEEEECCCCCCCHHCCCCCEEEECCHHHHCCHHHHCCCCEEEECCCC
AVAIGDGAAASADGSVAIGQGSGDNGRGVENYIGKYSNASNTSSGTVSVGNTATGETRTF
EEEECCCCCCCCCCCEEEECCCCCCCCCHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCH
SNVADGLQATDAVNLRQLDGIAASIVVVENNVSGLQNGTDGMFQVNNSSGLAKPSATGAN
HHHHCCHHHCCCCCHHHHCCCEEEEEEEECCCCCCCCCCCCEEEECCCCCCCCCCCCCCC
SATGGAGSVASGNNSTAFGSGAKATAANSAALGANSVADRANSVSVGSVGNERQITNVAP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCHHHHCCCCEEECCCCCCCEEEECCC
ATQGTDAVNFDQLKSISNQTNAYTNQRYSELKQDLRKQNSVLSAGIASAMSMASLTQPYT
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SGSSMTTIGAASYRGQSALSLGVSSISDSGRWGSKLQASSNTQGDFGIGVGVGYQW
CCCCEEEEECCCCCCCHHHHHHHHHCCCCCCCCCEEECCCCCCCCEEEEECCCCCC
>Mature Secondary Structure
MENIIKYDINYFLRFVCFNYFMNIKFYRGLFSISIVMIYLFIPGTATSQLYVNNADDQSC
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCEEEEECCCCCCE
YAIMDGPSVGPITSPNCNTPSIGIINTNAGQLFVGGTGAAVSGTLGPTFWTGTFATPVGT
EEEECCCCCCCCCCCCCCCCEEEEEECCCCEEEECCCCCEEECCCCCCEECCCEECCCCC
SNTATAYGMVVQSGGAYITGNTYVQGGLFLNGQKATNLAPATISSTSTDAVVGSQLYNLV
CCCCEEEEEEEECCCCEEECCEEEECCEEECCCCCCCCCCCEECCCCCHHHHHHHHHHHH
QDGTRYFHANSVNPTDSLASGLETIAVGPATVVSGDNGVGIGNTALVGTAATGGIAIGFG
HCCCEEEECCCCCCHHHHHHCCCEEECCCEEEEECCCCCCCCCCEEEEECCCCCEEEECC
TQVIAAGATAIGSAAQAQGAQSLALGAGAVTSQANSIALGAASINTVGAQSSYSAYALTA
CCEECCCCHHHCCHHHHCCCCCEEECCCHHHCCCCEEEEECCCCCCCCCCCCCCEEEEEC
PQVSVGELGIGTALGNRKITGVAAGSASSDAVNVAQLTAVGDQVQQNTANITSLGGRVTT
CCCCCCCCCCEEECCCCEEEEEECCCCCCCCEEHHHHHHHHHHHHHCCCCHHHCCCEEEE
IEGSMASIANGGGVKYFHANSTQPDSVASGTHSVAIGPASLASGAASLASGNAALASGAG
ECCCHHHHCCCCCEEEEECCCCCCCHHCCCCCEEEECCHHHHCCHHHHCCCCEEEECCCC
AVAIGDGAAASADGSVAIGQGSGDNGRGVENYIGKYSNASNTSSGTVSVGNTATGETRTF
EEEECCCCCCCCCCCEEEECCCCCCCCCHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCH
SNVADGLQATDAVNLRQLDGIAASIVVVENNVSGLQNGTDGMFQVNNSSGLAKPSATGAN
HHHHCCHHHCCCCCHHHHCCCEEEEEEEECCCCCCCCCCCCEEEECCCCCCCCCCCCCCC
SATGGAGSVASGNNSTAFGSGAKATAANSAALGANSVADRANSVSVGSVGNERQITNVAP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCHHHHCCCCEEECCCCCCCEEEECCC
ATQGTDAVNFDQLKSISNQTNAYTNQRYSELKQDLRKQNSVLSAGIASAMSMASLTQPYT
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SGSSMTTIGAASYRGQSALSLGVSSISDSGRWGSKLQASSNTQGDFGIGVGVGYQW
CCCCEEEEECCCCCCCHHHHHHHHHCCCCCCCCCEEECCCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2761389; 7934875; 2592347; 1548243 [H]