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The map label for this gene is visC [H]

Identifier: 170023114

GI number: 170023114

Start: 988750

End: 990093

Strand: Direct

Name: visC [H]

Synonym: YPK_0865

Alternate gene names: 170023114

Gene position: 988750-990093 (Clockwise)

Preceding gene: 170023113

Following gene: 170023115

Centisome position: 21.08

GC content: 53.94

Gene sequence:

>1344_bases
ATGGGGTGGCACAAATGCTGTTCAAATCGTTCCCGACCAATTTGCTTCTCGTTTGCCGCCTCCCTGCATCGAGAAATCCA
TAGAGTAAATAAAGTTCATATTTTCATGGGGAAATGTTTCGGCATGCAATCATTTGACATAGTTATCGCCGGTGGTGGGA
TGGTGGGTCTGGCGCTGGCTTGTGGTTTACAAGGCAGTGGCCTGCGTATCGCCATTATCGAGCATCAGCCTGCACCGATG
CCATTAACGGCGCCGTTGACCGGTGAGCTGGCACTGCGAGTCTCGGCGATCAACGCAGCTAGTGAGCGCTTACTGCAAAA
AATCGGGGTGTGGGAAACGATTCAGGCACTGCGTGCTAGCCCATACCACGGTATGGAAGTGTGGGATAAAGACAGCTTCG
GCAAAATTGCCTTTCATGCGGATGAATATGGCTTCAGCCATCTTGGCCATATCATTGAAAATCAGGTCATTCAACAAGCA
TTGTGGCAGCGGGCCAGCCAACTACCAGAGGTGACGGTCTTGGCACCCGCCAGCTTCAAACAAGTGGCTTGGGGCGAGAC
TGAAGCGTTTATCACCCTAACCGATGACCGGATGCTCAGTGCTCGGCTGGTTGTTGGGGCTGATGGCGCACACTCATGGT
TACGTCAGCATGCGGATATTCCTCTGACCTTCTGGGATTATGCCCACCATGCCTTGGTGGCAACTATCCGGACTGACGAG
CCGCATCAGGCTACCGCGCGTCAGGTATTCCACGGTGACGGCATTTTAGCTTTCCTCCCCTTTAGCGACCCCCACCTCAG
TTCTATTGTCTGGTCATTACCGCCTGAGCGTGCCGCCGAGTTAGCCGTGCTACCCGCCGAGCAATTTAACCGTGAGTTGG
CGATGACGTTTGATATGCGCCTTGGGCAATGTCAGCTTGAGAGTGAGCGGCAAACGTTCCCGCTGACCGGGCGTTATGCC
CGTAGCTTTGCCGCGCACCGGCTGGTGTTGGTCGGCGATGCGGCGCATACCGTGCATCCATTGGCTGGGCAGGGCGTTAA
TCTGGGCTTTATGGATGTAGCCGAATTAGTGTCTGAACTTCGGCGTTTACAGCGTCAAGGGAAGGATATTGGTCAGCATC
TCTATCTGCGCCGTTATGAACGCCGCCGCAAACACAGTGCTGCGATGATGCTGGCGAGTATGCAGGGCTTCCGTGATCTG
TTTGCTGGCAACAATCCGGCTAAAAAATTATTACGTGATATTGGGTTAACGCTGGCCGATCACTTGCCGGGGGTTAAACC
GCAATTGGTACGGCAGGCGATGGGGCTGAATGATTTGCCAGAATGGCTGGAGCGTTCTCAATAA

Upstream 100 bases:

>100_bases
ACAATACGTGATACTTTTGCCCGGCGTACATTGGGCTGGGTCGAGCGCTAACTCAATAGACTCATCGGGATTAACGCGCC
TCATCGTTGAGGTTTACCCT

Downstream 100 bases:

>100_bases
TACGCCGTTACGGGTATTAATGAGACACCGCCAGTGTGTGTCTAAAGCAGCCTTCGGTAGTGCCTCAAGCCGCGTGCGCT
CTGGCGCGGATGGGGCTTGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MGWHKCCSNRSRPICFSFAASLHREIHRVNKVHIFMGKCFGMQSFDIVIAGGGMVGLALACGLQGSGLRIAIIEHQPAPM
PLTAPLTGELALRVSAINAASERLLQKIGVWETIQALRASPYHGMEVWDKDSFGKIAFHADEYGFSHLGHIIENQVIQQA
LWQRASQLPEVTVLAPASFKQVAWGETEAFITLTDDRMLSARLVVGADGAHSWLRQHADIPLTFWDYAHHALVATIRTDE
PHQATARQVFHGDGILAFLPFSDPHLSSIVWSLPPERAAELAVLPAEQFNRELAMTFDMRLGQCQLESERQTFPLTGRYA
RSFAAHRLVLVGDAAHTVHPLAGQGVNLGFMDVAELVSELRRLQRQGKDIGQHLYLRRYERRRKHSAAMMLASMQGFRDL
FAGNNPAKKLLRDIGLTLADHLPGVKPQLVRQAMGLNDLPEWLERSQ

Sequences:

>Translated_447_residues
MGWHKCCSNRSRPICFSFAASLHREIHRVNKVHIFMGKCFGMQSFDIVIAGGGMVGLALACGLQGSGLRIAIIEHQPAPM
PLTAPLTGELALRVSAINAASERLLQKIGVWETIQALRASPYHGMEVWDKDSFGKIAFHADEYGFSHLGHIIENQVIQQA
LWQRASQLPEVTVLAPASFKQVAWGETEAFITLTDDRMLSARLVVGADGAHSWLRQHADIPLTFWDYAHHALVATIRTDE
PHQATARQVFHGDGILAFLPFSDPHLSSIVWSLPPERAAELAVLPAEQFNRELAMTFDMRLGQCQLESERQTFPLTGRYA
RSFAAHRLVLVGDAAHTVHPLAGQGVNLGFMDVAELVSELRRLQRQGKDIGQHLYLRRYERRRKHSAAMMLASMQGFRDL
FAGNNPAKKLLRDIGLTLADHLPGVKPQLVRQAMGLNDLPEWLERSQ
>Mature_446_residues
GWHKCCSNRSRPICFSFAASLHREIHRVNKVHIFMGKCFGMQSFDIVIAGGGMVGLALACGLQGSGLRIAIIEHQPAPMP
LTAPLTGELALRVSAINAASERLLQKIGVWETIQALRASPYHGMEVWDKDSFGKIAFHADEYGFSHLGHIIENQVIQQAL
WQRASQLPEVTVLAPASFKQVAWGETEAFITLTDDRMLSARLVVGADGAHSWLRQHADIPLTFWDYAHHALVATIRTDEP
HQATARQVFHGDGILAFLPFSDPHLSSIVWSLPPERAAELAVLPAEQFNRELAMTFDMRLGQCQLESERQTFPLTGRYAR
SFAAHRLVLVGDAAHTVHPLAGQGVNLGFMDVAELVSELRRLQRQGKDIGQHLYLRRYERRRKHSAAMMLASMQGFRDLF
AGNNPAKKLLRDIGLTLADHLPGVKPQLVRQAMGLNDLPEWLERSQ

Specific function: Not yet known [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Homo sapiens, GI32967305, Length=421, Percent_Identity=31.1163895486936, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI32967307, Length=347, Percent_Identity=31.700288184438, Blast_Score=139, Evalue=4e-33,
Organism=Escherichia coli, GI1789273, Length=403, Percent_Identity=71.4640198511166, Blast_Score=601, Evalue=1e-173,
Organism=Escherichia coli, GI1786883, Length=394, Percent_Identity=37.8172588832487, Blast_Score=242, Evalue=4e-65,
Organism=Escherichia coli, GI1789274, Length=397, Percent_Identity=31.9899244332494, Blast_Score=179, Evalue=4e-46,
Organism=Caenorhabditis elegans, GI25146631, Length=427, Percent_Identity=30.9133489461358, Blast_Score=171, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6321694, Length=458, Percent_Identity=25.9825327510917, Blast_Score=111, Evalue=3e-25,
Organism=Drosophila melanogaster, GI19920760, Length=432, Percent_Identity=33.7962962962963, Blast_Score=185, Evalue=5e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 49810; Mature: 49679

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: PS01304 UBIH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGWHKCCSNRSRPICFSFAASLHREIHRVNKVHIFMGKCFGMQSFDIVIAGGGMVGLALA
CCHHHHHCCCCCCCHHHHHHHHHHHHHHHCEEEEEEEHHCCCCCEEEEEECCCHHHHHHH
CGLQGSGLRIAIIEHQPAPMPLTAPLTGELALRVSAINAASERLLQKIGVWETIQALRAS
HCCCCCCEEEEEEECCCCCCCEECCCCCCEEEEEEHHHHHHHHHHHHHCHHHHHHHHHCC
PYHGMEVWDKDSFGKIAFHADEYGFSHLGHIIENQVIQQALWQRASQLPEVTVLAPASFK
CCCCCEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHH
QVAWGETEAFITLTDDRMLSARLVVGADGAHSWLRQHADIPLTFWDYAHHALVATIRTDE
HHHCCCCCEEEEEECCCEEEEEEEEECCCHHHHHHHCCCCCEEHHHHHCCEEEEEEECCC
PHQATARQVFHGDGILAFLPFSDPHLSSIVWSLPPERAAELAVLPAEQFNRELAMTFDMR
CCHHHHHHHHCCCCEEEEECCCCCHHHHHHHCCCHHHHHCEEEECHHHHCCEEEEEECCC
LGQCQLESERQTFPLTGRYARSFAAHRLVLVGDAAHTVHPLAGQGVNLGFMDVAELVSEL
CCCCEECCCCCCCCCCHHHHHHHHHCEEEEEECCHHHCCCCCCCCCCCCHHHHHHHHHHH
RRLQRQGKDIGQHLYLRRYERRRKHSAAMMLASMQGFRDLFAGNNPAKKLLRDIGLTLAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHH
HLPGVKPQLVRQAMGLNDLPEWLERSQ
HCCCCCHHHHHHHCCCCHHHHHHHCCC
>Mature Secondary Structure 
GWHKCCSNRSRPICFSFAASLHREIHRVNKVHIFMGKCFGMQSFDIVIAGGGMVGLALA
CHHHHHCCCCCCCHHHHHHHHHHHHHHHCEEEEEEEHHCCCCCEEEEEECCCHHHHHHH
CGLQGSGLRIAIIEHQPAPMPLTAPLTGELALRVSAINAASERLLQKIGVWETIQALRAS
HCCCCCCEEEEEEECCCCCCCEECCCCCCEEEEEEHHHHHHHHHHHHHCHHHHHHHHHCC
PYHGMEVWDKDSFGKIAFHADEYGFSHLGHIIENQVIQQALWQRASQLPEVTVLAPASFK
CCCCCEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHH
QVAWGETEAFITLTDDRMLSARLVVGADGAHSWLRQHADIPLTFWDYAHHALVATIRTDE
HHHCCCCCEEEEEECCCEEEEEEEEECCCHHHHHHHCCCCCEEHHHHHCCEEEEEEECCC
PHQATARQVFHGDGILAFLPFSDPHLSSIVWSLPPERAAELAVLPAEQFNRELAMTFDMR
CCHHHHHHHHCCCCEEEEECCCCCHHHHHHHCCCHHHHHCEEEECHHHHCCEEEEEECCC
LGQCQLESERQTFPLTGRYARSFAAHRLVLVGDAAHTVHPLAGQGVNLGFMDVAELVSEL
CCCCEECCCCCCCCCCHHHHHHHHHCEEEEEECCHHHCCCCCCCCCCCCHHHHHHHHHHH
RRLQRQGKDIGQHLYLRRYERRRKHSAAMMLASMQGFRDLFAGNNPAKKLLRDIGLTLAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHH
HLPGVKPQLVRQAMGLNDLPEWLERSQ
HCCCCCHHHHHHHCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on paired donors, with incorporation or reduction of molecular oxygen; With NADH2 or NADPH2 as one donor, and incorporation of one atom of oxygen [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1339425; 9278503 [H]