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The map label for this gene is speC [H]

Identifier: 170023060

GI number: 170023060

Start: 924843

End: 927005

Strand: Direct

Name: speC [H]

Synonym: YPK_0811

Alternate gene names: 170023060

Gene position: 924843-927005 (Clockwise)

Preceding gene: 170023059

Following gene: 170023061

Centisome position: 19.72

GC content: 45.26

Gene sequence:

>2163_bases
ATGACACTATTAAAAATAGCAACAAGCGCCCGCCTGGCTTCTTATGTAGAAACTCAGCGCGGAGTGGTGTACCTCAATCA
GACTGATTTTACTGATGTTGCCGCGGTGGTAATGTCGGTTGAAGATGCAAATGCGGGTATATTGTCAATGCTGCATGACC
TTGGTTTTGCTATTCCTGCATTTATTGCCGTGACGGCAGAACAGACGGTCTCTGCTGATTATTTGCCCTTGATTAAAGGT
GTCATTACGCTTGGTGAAGCAAATAAAGCTTTTTATAACGCTCAGGTAGAAGCTGCCGCCAGTGAATATCAAAAGAATCT
CTTACCGCCTTTTTTCTCAACACTGAAAAAATATGTCGAGATGAATAACTCGACCTTTGCTTGCCCTGGCCATCAGGGGG
GCGAATTTTTTCGCAAGCATCCTGCAGGACGCCAGTTTTTTGAATTCTACGGTGAGACGATTTTTCGTTCAGATATGTGT
AATGCCGATGTCAAATTAGGGGATTTACTTATCCATGAAGGGGCGGCAAAAGATGCACAGAAATATGCTGCTAAGGTATT
CAATGCCGATAAAACCTATTTTGTCCTGAACGGGACCTCGGCGGCCAACAAGGTCGTGACCAACGCTCTACTGACCCGTG
GTGATTTAGTGTTGTTTGACCGCAATAACCATAAATCTAACCATCATGGTGCGCTGATCCAGGCGGGCGCGACGCCGGTT
TATCTGGAAACGGCTCGTAACCCCTTTGGTTTTATTGGTGGTATTGATGCGCACTGCTTCAATGAAGATTATTTACGTCA
ACAACTGCGTGAAGTTGCTCCCGAGCGTGCAAAAGAGGCTCGGCCATTCCGATTAGCGATCATTCAATTGGGTACCTACG
ACGGTACGGTATATAACGCCCGACAAGTAGTTGATAGCATTGGTCATTTATGCGATTACATTTTGTTTGATTCTGCTTGG
GTGGGTTACGAACAATTTATTCCGATGATGAAGGATTTCTCACCGTTATTACTGGAATTAAATGAAAATGACCCTGGGAT
TATTGTGACTCAATCGGTACACAAGCAGCAGGCCGGTTTTTCTCAGACCTCTCAGGTACATAAAAAAGATAATCACATTA
AAGGACAGAAACGTCACTGTAACCATAAGCGTTTTAATAATGCCTTTATGTTGCATGCATCGACCAGTCCGTTTTATCCA
TTATTTGCGGCATTGGATGTTAATGCCAAAATACACTCTGGTGACAGTGGCCGCCGTATGTGGATGGATTGTGTAATACT
CGGTATTGAAACGCGTAAATCGTTATTGGTACGCTGTTCGATGTTACGGCCTTTTATTCCTCCAGTTGTTGGCGGTAAAA
ATTGGCAAGATTATGCTACGGATGTGATTGCCAATGATGCGCGCTTCTTTAATTTTGTTCCAGATGAACGCTGGCATGGA
TTTGAGGGATATAACCAAGATCAGTATTTGGTTGATCCGTGCAAATTATTGCTGACGACGCCGGGAATTGATGCCAGCAC
TGGCCGATATACTTCGTTTGGTATTCCGGCGGCTATTTTGGCGACTTTCCTGCGTGAAAATGGGATTGTGCCAGAAAAAT
GTGATCTTAACTCGATCCTATTCCTGCTGACCCCGGCAGAAAATACCGCCAAAATGGCACACCTAGTGGATATGTTGGTG
CAGTTTGAACGCTATGTTGAACAAGATGCGAAGCTGTGTGATGTATTACCGACGATCTATCGTAAGAATGAAGAGCGTTA
TCACGGTTATACCTTGCGTCAGTTATGCCAAGAAATGCATGACCTGTACGTCAGCCATGACGTTAAGCAATTGCAAAAGG
ATATGTTCCGTAAAGCCAGTTTCCCGCGGGTAGTCATGAACCCGCAAGACGCCAATATTCAGTTTATCCGCGATAATATT
GAGTTGATTCCTATTGCTGAAGCTGAAGGCCGTATTGCCGCCGAAGGCGCTTTGCCTTATCCACCGGGTGTGCTGTGTGT
GGTGCCCGGTGAAGTGTGGGGTGGGGCGGTTCAGCGTTATTTTCTGGCTCTGGAAGAGGGGATTAACTTACTGCCGGGCT
TTTCACCTGAGTTACAGGGCGTTTATATCGAAAAAGGTGATGTGTCTTGGCGGCGTATCTTTGGTTATGTGATTACGCAA
TAG

Upstream 100 bases:

>100_bases
GACATCAATTTACCGGCATTGCATCAGTGCTCCGCACTCTGTGATGTCATCGATAGGCCAAAATGGCAGCCTCATACCTG
ACCGTCTGAGAGTAAGTGAT

Downstream 100 bases:

>100_bases
TCTGATATTGCTCCGTTCCATCAGCCGAGGCCATTTTTTAATTGATGGCCTTGGTATTAAACATCTCATTCGCCCCGCCT
GATAACGCCATCGTTCATTT

Product: ornithine decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 720; Mature: 719

Protein sequence:

>720_residues
MTLLKIATSARLASYVETQRGVVYLNQTDFTDVAAVVMSVEDANAGILSMLHDLGFAIPAFIAVTAEQTVSADYLPLIKG
VITLGEANKAFYNAQVEAAASEYQKNLLPPFFSTLKKYVEMNNSTFACPGHQGGEFFRKHPAGRQFFEFYGETIFRSDMC
NADVKLGDLLIHEGAAKDAQKYAAKVFNADKTYFVLNGTSAANKVVTNALLTRGDLVLFDRNNHKSNHHGALIQAGATPV
YLETARNPFGFIGGIDAHCFNEDYLRQQLREVAPERAKEARPFRLAIIQLGTYDGTVYNARQVVDSIGHLCDYILFDSAW
VGYEQFIPMMKDFSPLLLELNENDPGIIVTQSVHKQQAGFSQTSQVHKKDNHIKGQKRHCNHKRFNNAFMLHASTSPFYP
LFAALDVNAKIHSGDSGRRMWMDCVILGIETRKSLLVRCSMLRPFIPPVVGGKNWQDYATDVIANDARFFNFVPDERWHG
FEGYNQDQYLVDPCKLLLTTPGIDASTGRYTSFGIPAAILATFLRENGIVPEKCDLNSILFLLTPAENTAKMAHLVDMLV
QFERYVEQDAKLCDVLPTIYRKNEERYHGYTLRQLCQEMHDLYVSHDVKQLQKDMFRKASFPRVVMNPQDANIQFIRDNI
ELIPIAEAEGRIAAEGALPYPPGVLCVVPGEVWGGAVQRYFLALEEGINLLPGFSPELQGVYIEKGDVSWRRIFGYVITQ

Sequences:

>Translated_720_residues
MTLLKIATSARLASYVETQRGVVYLNQTDFTDVAAVVMSVEDANAGILSMLHDLGFAIPAFIAVTAEQTVSADYLPLIKG
VITLGEANKAFYNAQVEAAASEYQKNLLPPFFSTLKKYVEMNNSTFACPGHQGGEFFRKHPAGRQFFEFYGETIFRSDMC
NADVKLGDLLIHEGAAKDAQKYAAKVFNADKTYFVLNGTSAANKVVTNALLTRGDLVLFDRNNHKSNHHGALIQAGATPV
YLETARNPFGFIGGIDAHCFNEDYLRQQLREVAPERAKEARPFRLAIIQLGTYDGTVYNARQVVDSIGHLCDYILFDSAW
VGYEQFIPMMKDFSPLLLELNENDPGIIVTQSVHKQQAGFSQTSQVHKKDNHIKGQKRHCNHKRFNNAFMLHASTSPFYP
LFAALDVNAKIHSGDSGRRMWMDCVILGIETRKSLLVRCSMLRPFIPPVVGGKNWQDYATDVIANDARFFNFVPDERWHG
FEGYNQDQYLVDPCKLLLTTPGIDASTGRYTSFGIPAAILATFLRENGIVPEKCDLNSILFLLTPAENTAKMAHLVDMLV
QFERYVEQDAKLCDVLPTIYRKNEERYHGYTLRQLCQEMHDLYVSHDVKQLQKDMFRKASFPRVVMNPQDANIQFIRDNI
ELIPIAEAEGRIAAEGALPYPPGVLCVVPGEVWGGAVQRYFLALEEGINLLPGFSPELQGVYIEKGDVSWRRIFGYVITQ
>Mature_719_residues
TLLKIATSARLASYVETQRGVVYLNQTDFTDVAAVVMSVEDANAGILSMLHDLGFAIPAFIAVTAEQTVSADYLPLIKGV
ITLGEANKAFYNAQVEAAASEYQKNLLPPFFSTLKKYVEMNNSTFACPGHQGGEFFRKHPAGRQFFEFYGETIFRSDMCN
ADVKLGDLLIHEGAAKDAQKYAAKVFNADKTYFVLNGTSAANKVVTNALLTRGDLVLFDRNNHKSNHHGALIQAGATPVY
LETARNPFGFIGGIDAHCFNEDYLRQQLREVAPERAKEARPFRLAIIQLGTYDGTVYNARQVVDSIGHLCDYILFDSAWV
GYEQFIPMMKDFSPLLLELNENDPGIIVTQSVHKQQAGFSQTSQVHKKDNHIKGQKRHCNHKRFNNAFMLHASTSPFYPL
FAALDVNAKIHSGDSGRRMWMDCVILGIETRKSLLVRCSMLRPFIPPVVGGKNWQDYATDVIANDARFFNFVPDERWHGF
EGYNQDQYLVDPCKLLLTTPGIDASTGRYTSFGIPAAILATFLRENGIVPEKCDLNSILFLLTPAENTAKMAHLVDMLVQ
FERYVEQDAKLCDVLPTIYRKNEERYHGYTLRQLCQEMHDLYVSHDVKQLQKDMFRKASFPRVVMNPQDANIQFIRDNIE
LIPIAEAEGRIAAEGALPYPPGVLCVVPGEVWGGAVQRYFLALEEGINLLPGFSPELQGVYIEKGDVSWRRIFGYVITQ

Specific function: Spermidine biosynthesis from ornithine. [C]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI87082193, Length=718, Percent_Identity=72.841225626741, Blast_Score=1109, Evalue=0.0,
Organism=Escherichia coli, GI1786909, Length=718, Percent_Identity=69.91643454039, Blast_Score=1071, Evalue=0.0,
Organism=Escherichia coli, GI221142684, Length=734, Percent_Identity=30.2452316076294, Blast_Score=347, Evalue=2e-96,
Organism=Escherichia coli, GI1790573, Length=612, Percent_Identity=33.6601307189542, Blast_Score=323, Evalue=2e-89,
Organism=Escherichia coli, GI1786384, Length=619, Percent_Identity=32.6332794830372, Blast_Score=312, Evalue=6e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR005308
- InterPro:   IPR011193
- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C; PF03709 OKR_DC_1_N [H]

EC number: =4.1.1.17 [H]

Molecular weight: Translated: 80786; Mature: 80655

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: PS00703 OKR_DC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLLKIATSARLASYVETQRGVVYLNQTDFTDVAAVVMSVEDANAGILSMLHDLGFAIPA
CCEEEEHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHEECCCCCHHHHHHHHHHHHHHH
FIAVTAEQTVSADYLPLIKGVITLGEANKAFYNAQVEAAASEYQKNLLPPFFSTLKKYVE
HHEEEHHHHCCCHHHHHHHHHHEECCCCCHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
MNNSTFACPGHQGGEFFRKHPAGRQFFEFYGETIFRSDMCNADVKLGDLLIHEGAAKDAQ
CCCCEEECCCCCCCHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCEEHHEEEECCCCHHHH
KYAAKVFNADKTYFVLNGTSAANKVVTNALLTRGDLVLFDRNNHKSNHHGALIQAGATPV
HHHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEECCCCEE
YLETARNPFGFIGGIDAHCFNEDYLRQQLREVAPERAKEARPFRLAIIQLGTYDGTVYNA
EEECCCCCCCCCCCCCHHCCCHHHHHHHHHHHCHHHHHCCCCEEEEEEEEECCCCCHHHH
RQVVDSIGHLCDYILFDSAWVGYEQFIPMMKDFSPLLLELNENDPGIIVTQSVHKQQAGF
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEECCCCCCEEEECCHHHHHCCC
SQTSQVHKKDNHIKGQKRHCNHKRFNNAFMLHASTSPFYPLFAALDVNAKIHSGDSGRRM
HHHHHHHHHCCCCCCCHHCCCCHHCCCEEEEEECCCCCCEEEEEEECCEEEECCCCCCCE
WMDCVILGIETRKSLLVRCSMLRPFIPPVVGGKNWQDYATDVIANDARFFNFVPDERWHG
EEEEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCEEECCCCCCCCC
FEGYNQDQYLVDPCKLLLTTPGIDASTGRYTSFGIPAAILATFLRENGIVPEKCDLNSIL
CCCCCCCCEEECCHHHEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEE
FLLTPAENTAKMAHLVDMLVQFERYVEQDAKLCDVLPTIYRKNEERYHGYTLRQLCQEMH
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCHHHHHHHHHHH
DLYVSHDVKQLQKDMFRKASFPRVVMNPQDANIQFIRDNIELIPIAEAEGRIAAEGALPY
HHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEEECCCEEEEEECCCCCEEECCCCCC
PPGVLCVVPGEVWGGAVQRYFLALEEGINLLPGFSPELQGVYIEKGDVSWRRIFGYVITQ
CCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHCCC
>Mature Secondary Structure 
TLLKIATSARLASYVETQRGVVYLNQTDFTDVAAVVMSVEDANAGILSMLHDLGFAIPA
CEEEEHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHEECCCCCHHHHHHHHHHHHHHH
FIAVTAEQTVSADYLPLIKGVITLGEANKAFYNAQVEAAASEYQKNLLPPFFSTLKKYVE
HHEEEHHHHCCCHHHHHHHHHHEECCCCCHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
MNNSTFACPGHQGGEFFRKHPAGRQFFEFYGETIFRSDMCNADVKLGDLLIHEGAAKDAQ
CCCCEEECCCCCCCHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCEEHHEEEECCCCHHHH
KYAAKVFNADKTYFVLNGTSAANKVVTNALLTRGDLVLFDRNNHKSNHHGALIQAGATPV
HHHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEECCCCEE
YLETARNPFGFIGGIDAHCFNEDYLRQQLREVAPERAKEARPFRLAIIQLGTYDGTVYNA
EEECCCCCCCCCCCCCHHCCCHHHHHHHHHHHCHHHHHCCCCEEEEEEEEECCCCCHHHH
RQVVDSIGHLCDYILFDSAWVGYEQFIPMMKDFSPLLLELNENDPGIIVTQSVHKQQAGF
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEECCCCCCEEEECCHHHHHCCC
SQTSQVHKKDNHIKGQKRHCNHKRFNNAFMLHASTSPFYPLFAALDVNAKIHSGDSGRRM
HHHHHHHHHCCCCCCCHHCCCCHHCCCEEEEEECCCCCCEEEEEEECCEEEECCCCCCCE
WMDCVILGIETRKSLLVRCSMLRPFIPPVVGGKNWQDYATDVIANDARFFNFVPDERWHG
EEEEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCEEECCCCCCCCC
FEGYNQDQYLVDPCKLLLTTPGIDASTGRYTSFGIPAAILATFLRENGIVPEKCDLNSIL
CCCCCCCCEEECCHHHEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEE
FLLTPAENTAKMAHLVDMLVQFERYVEQDAKLCDVLPTIYRKNEERYHGYTLRQLCQEMH
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCHHHHHHHHHHH
DLYVSHDVKQLQKDMFRKASFPRVVMNPQDANIQFIRDNIELIPIAEAEGRIAAEGALPY
HHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEEECCCEEEEEECCCCCEEECCCCCC
PPGVLCVVPGEVWGGAVQRYFLALEEGINLLPGFSPELQGVYIEKGDVSWRRIFGYVITQ
CCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]