Click here to switch to the map view.

The map label for this gene is treC [H]

Identifier: 170022745

GI number: 170022745

Start: 546202

End: 547863

Strand: Reverse

Name: treC [H]

Synonym: YPK_0494

Alternate gene names: 170022745

Gene position: 547863-546202 (Counterclockwise)

Preceding gene: 170022746

Following gene: 170022744

Centisome position: 11.68

GC content: 50.06

Gene sequence:

>1662_bases
ATGAATAATCCAATCCCTTGGTGGCAACATGGTGTCATCTATCAGATTTACCCGAAGAGCTTTCAGGACAGTACCGGTAA
TGGCTATGGTGACCTGGCAGGCGTTGCGCAGCGGCTGGATTATCTGCAAAAGCTGGGCGTTGATGCCATCTGGCTGACAC
CGGTGTATGTCTCGCCACAAGTGGATAACGGTTATGACGTGGCGGATTACTGCGCCATTGACCCCGCTTATGGCACATTG
GATGACTTTAAACGTTTGGTCGCGGGTGCTCATCAGCGAGGCATACGCATCATCATGGATATGGTGTTCAATCACACCTC
CACAGAACATGCCTGGTTTAAAGCTTCGCAGGATCGTAATAGCCCTTATCGGCAATTTTATATTTGGCGTGACGGTGGAG
ACGGCAGTTTACCGAATAACTGGCGCTCGAAATTCGGTGGTCACGCATGGCAGTGGCACGCGGCCAGCGGCCAGTATTAT
CTGCATTTGTTTGCCCCAGAACAGGCTGATCTGAATTGGGAACACCAACCGGTACGCGATGAGCTCAAAAAGGTGTGTGA
ATTTTGGGCCGATCTGGGGGTTGATGGTCTGCGTTTGGATGTCATCAATCTGGTGTCCAAACAGCAGGATTTCCCTAATG
ATCTGGACGGCGATGGCCGCCGTTTTTATACCGATGGCCCACGCATTCATGAGTTTTTGCAGGAACTGAGCCGCGATGTG
TTCCAGCCACGCCGCCTGATGACGGTAGGCGAGATGTCATCCACCCGTCTCGAGCATTGTCAGCGATATGCGGCATTAGG
CGGTGATGAGTTATCCATGACCTTTAATTTCCATCACCTGAAAGTGGATTATCTTAACGGTGAAAAGTGGTCATTGATGC
CGCCGAATCGGGTGGAGTTGAAACACATTTTTAATCAGTGGCAGCAAGGGATGCACAACCGAGCATGGAACGCACTATTT
TGGTGTAATCACGATCAACCACGCATTGTCTCGCGTTTTGGTCATGAAGGCGCACTACGTTTGCCAGCGGCAAAGATGCT
GGCGATGGTACTGCACGGTATGCAGGGCACGCCTTATATTTATCAGGGGGAAGAAATTGGCATGACGAACCCCAATTTCA
CTGATATCACTCAATACCGTGATGTTGAAAGCCTGAATATGTTTGCCGAACTGAGTGTGGCAGGCCGCGAACCCGATGAG
TTATTGGCGATTCTGGCAGCTAAATCCCGTGATAATAGCCGTACCCCCATGCAATGGGATAGCAGCGATAATGCGGGTTT
CAGCCAAGGCACTCCCTGGATTGCCCCTTGCAGCAATTATCATGAGATTAACGTTAATGCCGCATTGGCCGACGCTGACT
CGGTGTTTTATGCCTATCAATACCTGATAGCCCTGCGTAAACAATACGATATTTTCACTTTCGGTGATTATCAGGATCTT
TGCCCACAGCATCCTGATTTATGGTGCTATTTGCGCAGTTGGCAAGGGAAGCAACTGTTGGTAGTCGCTAACCTGAGTGA
AGAGCCCCAGCGATGGCAACCCGAGGGCCTCACGCTGGACGGTAATTGGCAATTATTGATGAGCAGCTACGACCAAAGCG
CCTTCCAACCGCAAGATATGATATTACGCGGATATGAGGGGATTTATTGGGTATGTGAATAA

Upstream 100 bases:

>100_bases
GTCTGAAGGGTGTCGATCTGGATGATGTCGATATAAGTTGTGTTCTCCCGCCAGCGGTGATCGTCTGGCGGGGTCATTTT
TCAATGAATAAGAGTCCGCT

Downstream 100 bases:

>100_bases
TTTATTGGGCGCATGGGTCATTGAATCGGTGTGTAGGTCATTTCATTGAGTAAACGCGTTATTTTTCGAAGGGCCGGTGA
TAGGTGACTCCATCAGTGCA

Product: trehalose-6-phosphate hydrolase

Products: NA

Alternate protein names: Alpha,alpha-phosphotrehalase [H]

Number of amino acids: Translated: 553; Mature: 553

Protein sequence:

>553_residues
MNNPIPWWQHGVIYQIYPKSFQDSTGNGYGDLAGVAQRLDYLQKLGVDAIWLTPVYVSPQVDNGYDVADYCAIDPAYGTL
DDFKRLVAGAHQRGIRIIMDMVFNHTSTEHAWFKASQDRNSPYRQFYIWRDGGDGSLPNNWRSKFGGHAWQWHAASGQYY
LHLFAPEQADLNWEHQPVRDELKKVCEFWADLGVDGLRLDVINLVSKQQDFPNDLDGDGRRFYTDGPRIHEFLQELSRDV
FQPRRLMTVGEMSSTRLEHCQRYAALGGDELSMTFNFHHLKVDYLNGEKWSLMPPNRVELKHIFNQWQQGMHNRAWNALF
WCNHDQPRIVSRFGHEGALRLPAAKMLAMVLHGMQGTPYIYQGEEIGMTNPNFTDITQYRDVESLNMFAELSVAGREPDE
LLAILAAKSRDNSRTPMQWDSSDNAGFSQGTPWIAPCSNYHEINVNAALADADSVFYAYQYLIALRKQYDIFTFGDYQDL
CPQHPDLWCYLRSWQGKQLLVVANLSEEPQRWQPEGLTLDGNWQLLMSSYDQSAFQPQDMILRGYEGIYWVCE

Sequences:

>Translated_553_residues
MNNPIPWWQHGVIYQIYPKSFQDSTGNGYGDLAGVAQRLDYLQKLGVDAIWLTPVYVSPQVDNGYDVADYCAIDPAYGTL
DDFKRLVAGAHQRGIRIIMDMVFNHTSTEHAWFKASQDRNSPYRQFYIWRDGGDGSLPNNWRSKFGGHAWQWHAASGQYY
LHLFAPEQADLNWEHQPVRDELKKVCEFWADLGVDGLRLDVINLVSKQQDFPNDLDGDGRRFYTDGPRIHEFLQELSRDV
FQPRRLMTVGEMSSTRLEHCQRYAALGGDELSMTFNFHHLKVDYLNGEKWSLMPPNRVELKHIFNQWQQGMHNRAWNALF
WCNHDQPRIVSRFGHEGALRLPAAKMLAMVLHGMQGTPYIYQGEEIGMTNPNFTDITQYRDVESLNMFAELSVAGREPDE
LLAILAAKSRDNSRTPMQWDSSDNAGFSQGTPWIAPCSNYHEINVNAALADADSVFYAYQYLIALRKQYDIFTFGDYQDL
CPQHPDLWCYLRSWQGKQLLVVANLSEEPQRWQPEGLTLDGNWQLLMSSYDQSAFQPQDMILRGYEGIYWVCE
>Mature_553_residues
MNNPIPWWQHGVIYQIYPKSFQDSTGNGYGDLAGVAQRLDYLQKLGVDAIWLTPVYVSPQVDNGYDVADYCAIDPAYGTL
DDFKRLVAGAHQRGIRIIMDMVFNHTSTEHAWFKASQDRNSPYRQFYIWRDGGDGSLPNNWRSKFGGHAWQWHAASGQYY
LHLFAPEQADLNWEHQPVRDELKKVCEFWADLGVDGLRLDVINLVSKQQDFPNDLDGDGRRFYTDGPRIHEFLQELSRDV
FQPRRLMTVGEMSSTRLEHCQRYAALGGDELSMTFNFHHLKVDYLNGEKWSLMPPNRVELKHIFNQWQQGMHNRAWNALF
WCNHDQPRIVSRFGHEGALRLPAAKMLAMVLHGMQGTPYIYQGEEIGMTNPNFTDITQYRDVESLNMFAELSVAGREPDE
LLAILAAKSRDNSRTPMQWDSSDNAGFSQGTPWIAPCSNYHEINVNAALADADSVFYAYQYLIALRKQYDIFTFGDYQDL
CPQHPDLWCYLRSWQGKQLLVVANLSEEPQRWQPEGLTLDGNWQLLMSSYDQSAFQPQDMILRGYEGIYWVCE

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=486, Percent_Identity=30.2469135802469, Blast_Score=244, Evalue=1e-64,
Organism=Homo sapiens, GI61744483, Length=112, Percent_Identity=35.7142857142857, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI61744479, Length=112, Percent_Identity=35.7142857142857, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI61744481, Length=112, Percent_Identity=35.7142857142857, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI65506891, Length=112, Percent_Identity=35.7142857142857, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI61744475, Length=112, Percent_Identity=35.7142857142857, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI61744477, Length=112, Percent_Identity=35.7142857142857, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI1790687, Length=545, Percent_Identity=74.1284403669725, Blast_Score=837, Evalue=0.0,
Organism=Escherichia coli, GI1786604, Length=358, Percent_Identity=26.536312849162, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1789995, Length=91, Percent_Identity=38.4615384615385, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI32565753, Length=376, Percent_Identity=24.7340425531915, Blast_Score=118, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI25147709, Length=479, Percent_Identity=25.4697286012526, Blast_Score=116, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6322245, Length=538, Percent_Identity=36.8029739776952, Blast_Score=341, Evalue=2e-94,
Organism=Saccharomyces cerevisiae, GI6321726, Length=582, Percent_Identity=34.5360824742268, Blast_Score=331, Evalue=2e-91,
Organism=Saccharomyces cerevisiae, GI6322241, Length=584, Percent_Identity=35.2739726027397, Blast_Score=324, Evalue=3e-89,
Organism=Saccharomyces cerevisiae, GI6322021, Length=584, Percent_Identity=35.2739726027397, Blast_Score=324, Evalue=3e-89,
Organism=Saccharomyces cerevisiae, GI6324416, Length=584, Percent_Identity=35.2739726027397, Blast_Score=324, Evalue=3e-89,
Organism=Saccharomyces cerevisiae, GI6321731, Length=586, Percent_Identity=33.9590443686007, Blast_Score=305, Evalue=8e-84,
Organism=Saccharomyces cerevisiae, GI6319776, Length=586, Percent_Identity=33.7883959044369, Blast_Score=304, Evalue=3e-83,
Organism=Drosophila melanogaster, GI24583749, Length=542, Percent_Identity=34.6863468634686, Blast_Score=268, Evalue=9e-72,
Organism=Drosophila melanogaster, GI24583747, Length=542, Percent_Identity=34.6863468634686, Blast_Score=268, Evalue=1e-71,
Organism=Drosophila melanogaster, GI221330053, Length=497, Percent_Identity=36.2173038229376, Blast_Score=263, Evalue=3e-70,
Organism=Drosophila melanogaster, GI24583745, Length=545, Percent_Identity=33.394495412844, Blast_Score=259, Evalue=4e-69,
Organism=Drosophila melanogaster, GI24586599, Length=529, Percent_Identity=32.5141776937618, Blast_Score=256, Evalue=2e-68,
Organism=Drosophila melanogaster, GI24586597, Length=496, Percent_Identity=34.2741935483871, Blast_Score=255, Evalue=5e-68,
Organism=Drosophila melanogaster, GI45549022, Length=528, Percent_Identity=33.3333333333333, Blast_Score=255, Evalue=5e-68,
Organism=Drosophila melanogaster, GI24586593, Length=497, Percent_Identity=32.5955734406439, Blast_Score=254, Evalue=1e-67,
Organism=Drosophila melanogaster, GI24586589, Length=533, Percent_Identity=33.9587242026266, Blast_Score=247, Evalue=2e-65,
Organism=Drosophila melanogaster, GI24586591, Length=495, Percent_Identity=32.3232323232323, Blast_Score=244, Evalue=1e-64,
Organism=Drosophila melanogaster, GI24586587, Length=512, Percent_Identity=30.46875, Blast_Score=235, Evalue=6e-62,
Organism=Drosophila melanogaster, GI281360393, Length=440, Percent_Identity=30, Blast_Score=181, Evalue=9e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR012769 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.93 [H]

Molecular weight: Translated: 63905; Mature: 63905

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNPIPWWQHGVIYQIYPKSFQDSTGNGYGDLAGVAQRLDYLQKLGVDAIWLTPVYVSPQ
CCCCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEECCC
VDNGYDVADYCAIDPAYGTLDDFKRLVAGAHQRGIRIIMDMVFNHTSTEHAWFKASQDRN
CCCCCCHHHHEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEECCCCCC
SPYRQFYIWRDGGDGSLPNNWRSKFGGHAWQWHAASGQYYLHLFAPEQADLNWEHQPVRD
CCCEEEEEEEECCCCCCCCHHHHHCCCCEEEEEECCCCEEEEEECCCCCCCCCCCCCHHH
ELKKVCEFWADLGVDGLRLDVINLVSKQQDFPNDLDGDGRRFYTDGPRIHEFLQELSRDV
HHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHH
FQPRRLMTVGEMSSTRLEHCQRYAALGGDELSMTFNFHHLKVDYLNGEKWSLMPPNRVEL
HCCHHEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEEEECCCEEECCCCCHHHH
KHIFNQWQQGMHNRAWNALFWCNHDQPRIVSRFGHEGALRLPAAKMLAMVLHGMQGTPYI
HHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHCCCCCCEECCHHHHHHHHHHCCCCCCEE
YQGEEIGMTNPNFTDITQYRDVESLNMFAELSVAGREPDELLAILAAKSRDNSRTPMQWD
EECCEECCCCCCCCCHHHHCCHHHHHHEEEEEECCCCHHHHHHHHHHCCCCCCCCCCEEC
SSDNAGFSQGTPWIAPCSNYHEINVNAALADADSVFYAYQYLIALRKQYDIFTFGDYQDL
CCCCCCCCCCCCCEECCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHCCEEEECCHHHH
CPQHPDLWCYLRSWQGKQLLVVANLSEEPQRWQPEGLTLDGNWQLLMSSYDQSAFQPQDM
CCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCEEECCCCEEEEECCCCCCCCCHHH
ILRGYEGIYWVCE
HHCCCCCEEEEEC
>Mature Secondary Structure
MNNPIPWWQHGVIYQIYPKSFQDSTGNGYGDLAGVAQRLDYLQKLGVDAIWLTPVYVSPQ
CCCCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEECCC
VDNGYDVADYCAIDPAYGTLDDFKRLVAGAHQRGIRIIMDMVFNHTSTEHAWFKASQDRN
CCCCCCHHHHEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEECCCCCC
SPYRQFYIWRDGGDGSLPNNWRSKFGGHAWQWHAASGQYYLHLFAPEQADLNWEHQPVRD
CCCEEEEEEEECCCCCCCCHHHHHCCCCEEEEEECCCCEEEEEECCCCCCCCCCCCCHHH
ELKKVCEFWADLGVDGLRLDVINLVSKQQDFPNDLDGDGRRFYTDGPRIHEFLQELSRDV
HHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHH
FQPRRLMTVGEMSSTRLEHCQRYAALGGDELSMTFNFHHLKVDYLNGEKWSLMPPNRVEL
HCCHHEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEEEECCCEEECCCCCHHHH
KHIFNQWQQGMHNRAWNALFWCNHDQPRIVSRFGHEGALRLPAAKMLAMVLHGMQGTPYI
HHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHCCCCCCEECCHHHHHHHHHHCCCCCCEE
YQGEEIGMTNPNFTDITQYRDVESLNMFAELSVAGREPDELLAILAAKSRDNSRTPMQWD
EECCEECCCCCCCCCHHHHCCHHHHHHEEEEEECCCCHHHHHHHHHHCCCCCCCCCCEEC
SSDNAGFSQGTPWIAPCSNYHEINVNAALADADSVFYAYQYLIALRKQYDIFTFGDYQDL
CCCCCCCCCCCCCEECCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHCCEEEECCHHHH
CPQHPDLWCYLRSWQGKQLLVVANLSEEPQRWQPEGLTLDGNWQLLMSSYDQSAFQPQDM
CCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCEEECCCCEEEEECCCCCCCCCHHH
ILRGYEGIYWVCE
HHCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8083158; 7610040; 9278503; 8421692 [H]