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The map label for this gene is slyD [H]

Identifier: 170022529

GI number: 170022529

Start: 308641

End: 309222

Strand: Direct

Name: slyD [H]

Synonym: YPK_0268

Alternate gene names: 170022529

Gene position: 308641-309222 (Clockwise)

Preceding gene: 170022528

Following gene: 170022531

Centisome position: 6.58

GC content: 52.75

Gene sequence:

>582_bases
ATGAAAGTAACAAAAGACTTGGTAGTCAGCCTGGCTTACCAGGTACGTACAGAAGACGGTGTTTTAGTTGATGAGTCTCC
GGTGAGCGCGCCGTTGGACTACCTGCACGGGCACGGTTCCCTGATCGCTGGTTTAGAAAACGCGCTCGAAGGCCACGAAG
CTGGTGACAGTTTTGATGTGCGTGTTAATGCCGATGAAGGTTACGGCAGCTACGATGAAAATCTGGTGCAGCGTGTACCA
AAAGACGTCTTTATGGGCGTTGACGAGCTGGAAGTGGGGATGCGTTTTCTGGCAGATACTGATCAAGGCCCAGTACCGGT
TGAGATCACTGCTGTCGAAGACGAGCACGTCGTGGTTGATGGTAACCACATGCTGGCGGGCCAGGATCTGAACTTCCACG
TTGAAGTGGTTGCTGTCCGTGAAGCAACAGAAGAAGAGTTGCAGCACGGCCATGTACATGGTGAGCATGATCATCACCAT
GAACACGGTGACGGTTGCTGCGGTGGTCACGGCCACGACGACCATGAACATGAGCATGGTAAAGGTGGTTGCGGTAAAAG
TGGCGGTTGTGGCTGTCACTAA

Upstream 100 bases:

>100_bases
GAGTAGCGTTATCTGCCGTGATTTTTTATGCGGGTGAGTACAGCGGGGCAGATTTCCGCTACAATCTGTGCCAATTTTTG
TTCCAAGGGTAGGAGATATC

Downstream 100 bases:

>100_bases
TATCTGACCCCGTCAGCAAAAAGCCAGCCTTCATCGCTGGCTTTTTGCTCTGTACGCGATCACTCATTTTCTGTGTGATA
GCCAATGATCTCGTCATAAC

Product: FKBP-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase; Metallochaperone slyD [H]

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MKVTKDLVVSLAYQVRTEDGVLVDESPVSAPLDYLHGHGSLIAGLENALEGHEAGDSFDVRVNADEGYGSYDENLVQRVP
KDVFMGVDELEVGMRFLADTDQGPVPVEITAVEDEHVVVDGNHMLAGQDLNFHVEVVAVREATEEELQHGHVHGEHDHHH
EHGDGCCGGHGHDDHEHEHGKGGCGKSGGCGCH

Sequences:

>Translated_193_residues
MKVTKDLVVSLAYQVRTEDGVLVDESPVSAPLDYLHGHGSLIAGLENALEGHEAGDSFDVRVNADEGYGSYDENLVQRVP
KDVFMGVDELEVGMRFLADTDQGPVPVEITAVEDEHVVVDGNHMLAGQDLNFHVEVVAVREATEEELQHGHVHGEHDHHH
EHGDGCCGGHGHDDHEHEHGKGGCGKSGGCGCH
>Mature_193_residues
MKVTKDLVVSLAYQVRTEDGVLVDESPVSAPLDYLHGHGSLIAGLENALEGHEAGDSFDVRVNADEGYGSYDENLVQRVP
KDVFMGVDELEVGMRFLADTDQGPVPVEITAVEDEHVVVDGNHMLAGQDLNFHVEVVAVREATEEELQHGHVHGEHDHHH
EHGDGCCGGHGHDDHEHEHGKGGCGKSGGCGCH

Specific function: Also involved in hydrogenase metallocenter assembly, probably by participating in the nickel insertion step. This function in hydrogenase biosynthesis requires chaperone activity and the presence of the metal-binding domain, but not PPIase activity [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789748, Length=147, Percent_Identity=87.7551020408163, Blast_Score=261, Evalue=2e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 20786; Mature: 20786

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVTKDLVVSLAYQVRTEDGVLVDESPVSAPLDYLHGHGSLIAGLENALEGHEAGDSFDV
CCCHHHHHHHHHHEEECCCCEEEECCCCCCCHHHHCCCCHHHHHHHHHHCCCCCCCCEEE
RVNADEGYGSYDENLVQRVPKDVFMGVDELEVGMRFLADTDQGPVPVEITAVEDEHVVVD
EEECCCCCCCHHHHHHHHCCHHHHCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCEEEEE
GNHMLAGQDLNFHVEVVAVREATEEELQHGHVHGEHDHHHEHGDGCCGGHGHDDHEHEHG
CCEEEECCCCCEEEEEEEECHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
KGGCGKSGGCGCH
CCCCCCCCCCCCC
>Mature Secondary Structure
MKVTKDLVVSLAYQVRTEDGVLVDESPVSAPLDYLHGHGSLIAGLENALEGHEAGDSFDV
CCCHHHHHHHHHHEEECCCCEEEECCCCCCCHHHHCCCCHHHHHHHHHHCCCCCCCCEEE
RVNADEGYGSYDENLVQRVPKDVFMGVDELEVGMRFLADTDQGPVPVEITAVEDEHVVVD
EEECCCCCCCHHHHHHHHCCHHHHCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCEEEEE
GNHMLAGQDLNFHVEVVAVREATEEELQHGHVHGEHDHHHEHGDGCCGGHGHDDHEHEHG
CCEEEECCCCCEEEEEEEECHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
KGGCGKSGGCGCH
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]