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The map label for this gene is codA [H]

Identifier: 170022498

GI number: 170022498

Start: 275768

End: 277066

Strand: Direct

Name: codA [H]

Synonym: YPK_0237

Alternate gene names: 170022498

Gene position: 275768-277066 (Clockwise)

Preceding gene: 170022492

Following gene: 170022500

Centisome position: 5.88

GC content: 51.66

Gene sequence:

>1299_bases
ATGGCAGGGCAATCTGTACCGAATTATTCATTAACGACGGTAAATAATGTGCGTCGTATAGGGTTAGCGGGGCTGTGGCA
GATAACGATAGCGGAAGGCAAAATCAGCCTGATTCAGCCTCAGCCGGAGCAATCCCTAACAGGGCAAGGTGTGCTGGATG
CGCAGGGCGGTTTGGCGCTCCCGCCATTTATTGAGCCGCATATTCATCTGGATACGACTCAAACCGCTGGGCAACCGAGT
TGGAATCAGTCGGGAACTCTGTTTGAGGGAATTGAACGTTGGGCGGAGCGCAAAGCGCGACTAACGCGCGAGGATGTGAA
GCAGCGGGCCTGGCAAACATTGAAATGGCAGATAGCCAACGGTATCCAGCATGTCCGAACGCATGTTGATGTTTCCGATC
CACACTTGACGGCATTGAGCGCCATGTTGGAGGTGAAAGAAGAGGTTAGCCCTTGGGTTGATATGCAGATTGTGGCTTTC
CCACAAGAGGGCATCCTCTCTTATCCTGATGGTGCGGCGTTATTGGAAGAGGCACTGCGCTTGGGTGCGGATGCGGTGGG
GGCGATCCCCCATTTTGAATTTACCCGCGAATATGGCGTGGAATCTTTGCATATCGCGTTTGCATTGGCGCAAAAATATC
AGCGGCTGGTGGATGTTCATTGCGATGAAACGGATGATGAGCAATCGCGCTTTATCGAAACCGTGGCGGCGCTGGCCCTT
CGCGAAAATATGGGCGCACGGGTAACCGCCAGCCATACCACGGCGATGCACTCTTATAATGGTGCCTATACATCACGGCT
GTTCCGCTTGCTGAAATTATCGGGCATTAATTTTGTCGCCAATCCGCTGGTGAATATTCATCTGCAAGGCCGTTTTGATA
CTTATCCGAAGCGGCGTGGTATCACGCGGGTCAAAGAGATGTTGGCTGCCGAGATTAATGTGTGCTTCGGCCATGACGAT
GTGTTCGACCCGTGGTATCCGCTAGGTACCGCCAATATGTTGCAGGTGCTGCATATGGGATTACATATTTGTCAGTTGAT
GGGATATGAACAAATTAATGATGGTCTGAATCTGATAACCACCCACAGTGCCAAGACGCTGAATTTAGCAGATTACGGTT
TGCAGCCTGGTAACCGCGCCAACCTGATTATTCTACCCGCAGAAAATGGTTTTGATGCTCTACGGCGGCAGGTTCCCGTC
AGTTACTCTATTCGTCATGGTGTGGTGATCGCGAAGACGCAACCCGCAGAGAGCCGGATCTATTTGGGGCAGGAAGAGAT
CGTGGATTTTCGGCGTTAA

Upstream 100 bases:

>100_bases
ATGAGTAAAAGAAAATCGGGCAGGCGACGGTGGCTCAGGTAAGCTAAAGAAAACCGCTTTTCGTGATGACGAGAGGAGGA
AAGAGAGAGTGGAGGCATTG

Downstream 100 bases:

>100_bases
CGGTAGGATTTTCGATGTTTACGGCATTAGTGAATCATCAATACCCTGCCACCTTGGCGGCGGCAGGGCGGTAACGCAGA
TAAATCAGTGGGTCACGTGG

Product: cytosine deaminase

Products: NA

Alternate protein names: Cytosine aminohydrolase [H]

Number of amino acids: Translated: 432; Mature: 431

Protein sequence:

>432_residues
MAGQSVPNYSLTTVNNVRRIGLAGLWQITIAEGKISLIQPQPEQSLTGQGVLDAQGGLALPPFIEPHIHLDTTQTAGQPS
WNQSGTLFEGIERWAERKARLTREDVKQRAWQTLKWQIANGIQHVRTHVDVSDPHLTALSAMLEVKEEVSPWVDMQIVAF
PQEGILSYPDGAALLEEALRLGADAVGAIPHFEFTREYGVESLHIAFALAQKYQRLVDVHCDETDDEQSRFIETVAALAL
RENMGARVTASHTTAMHSYNGAYTSRLFRLLKLSGINFVANPLVNIHLQGRFDTYPKRRGITRVKEMLAAEINVCFGHDD
VFDPWYPLGTANMLQVLHMGLHICQLMGYEQINDGLNLITTHSAKTLNLADYGLQPGNRANLIILPAENGFDALRRQVPV
SYSIRHGVVIAKTQPAESRIYLGQEEIVDFRR

Sequences:

>Translated_432_residues
MAGQSVPNYSLTTVNNVRRIGLAGLWQITIAEGKISLIQPQPEQSLTGQGVLDAQGGLALPPFIEPHIHLDTTQTAGQPS
WNQSGTLFEGIERWAERKARLTREDVKQRAWQTLKWQIANGIQHVRTHVDVSDPHLTALSAMLEVKEEVSPWVDMQIVAF
PQEGILSYPDGAALLEEALRLGADAVGAIPHFEFTREYGVESLHIAFALAQKYQRLVDVHCDETDDEQSRFIETVAALAL
RENMGARVTASHTTAMHSYNGAYTSRLFRLLKLSGINFVANPLVNIHLQGRFDTYPKRRGITRVKEMLAAEINVCFGHDD
VFDPWYPLGTANMLQVLHMGLHICQLMGYEQINDGLNLITTHSAKTLNLADYGLQPGNRANLIILPAENGFDALRRQVPV
SYSIRHGVVIAKTQPAESRIYLGQEEIVDFRR
>Mature_431_residues
AGQSVPNYSLTTVNNVRRIGLAGLWQITIAEGKISLIQPQPEQSLTGQGVLDAQGGLALPPFIEPHIHLDTTQTAGQPSW
NQSGTLFEGIERWAERKARLTREDVKQRAWQTLKWQIANGIQHVRTHVDVSDPHLTALSAMLEVKEEVSPWVDMQIVAFP
QEGILSYPDGAALLEEALRLGADAVGAIPHFEFTREYGVESLHIAFALAQKYQRLVDVHCDETDDEQSRFIETVAALALR
ENMGARVTASHTTAMHSYNGAYTSRLFRLLKLSGINFVANPLVNIHLQGRFDTYPKRRGITRVKEMLAAEINVCFGHDDV
FDPWYPLGTANMLQVLHMGLHICQLMGYEQINDGLNLITTHSAKTLNLADYGLQPGNRANLIILPAENGFDALRRQVPVS
YSIRHGVVIAKTQPAESRIYLGQEEIVDFRR

Specific function: Unknown

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786531, Length=427, Percent_Identity=80.0936768149883, Blast_Score=716, Evalue=0.0,
Organism=Escherichia coli, GI1786517, Length=321, Percent_Identity=25.5451713395639, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013108
- InterPro:   IPR011059 [H]

Pfam domain/function: PF07969 Amidohydro_3 [H]

EC number: =3.5.4.1 [H]

Molecular weight: Translated: 48184; Mature: 48052

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGQSVPNYSLTTVNNVRRIGLAGLWQITIAEGKISLIQPQPEQSLTGQGVLDAQGGLAL
CCCCCCCCCEEEEHHHHHHHCCCEEEEEEEECCEEEEECCCCCCCCCCCCEEECCCCCCC
PPFIEPHIHLDTTQTAGQPSWNQSGTLFEGIERWAERKARLTREDVKQRAWQTLKWQIAN
CCCCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
GIQHVRTHVDVSDPHLTALSAMLEVKEEVSPWVDMQIVAFPQEGILSYPDGAALLEEALR
HHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHH
LGADAVGAIPHFEFTREYGVESLHIAFALAQKYQRLVDVHCDETDDEQSRFIETVAALAL
HCCHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
RENMGARVTASHTTAMHSYNGAYTSRLFRLLKLSGINFVANPLVNIHLQGRFDTYPKRRG
HHCCCCEEEECCHHHHHCCCCHHHHHHHHHHHHCCCCEEECCEEEEEEECCCCCCCHHCC
ITRVKEMLAAEINVCFGHDDVFDPWYPLGTANMLQVLHMGLHICQLMGYEQINDGLNLIT
HHHHHHHHHHHHHEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHCCCCCEEE
THSAKTLNLADYGLQPGNRANLIILPAENGFDALRRQVPVSYSIRHGVVIAKTQPAESRI
ECCCCEEEHHHCCCCCCCCCCEEEEECCCCHHHHHHCCCCEEEECCCEEEEECCCCCCEE
YLGQEEIVDFRR
EECHHHHHHCCC
>Mature Secondary Structure 
AGQSVPNYSLTTVNNVRRIGLAGLWQITIAEGKISLIQPQPEQSLTGQGVLDAQGGLAL
CCCCCCCCEEEEHHHHHHHCCCEEEEEEEECCEEEEECCCCCCCCCCCCEEECCCCCCC
PPFIEPHIHLDTTQTAGQPSWNQSGTLFEGIERWAERKARLTREDVKQRAWQTLKWQIAN
CCCCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
GIQHVRTHVDVSDPHLTALSAMLEVKEEVSPWVDMQIVAFPQEGILSYPDGAALLEEALR
HHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHH
LGADAVGAIPHFEFTREYGVESLHIAFALAQKYQRLVDVHCDETDDEQSRFIETVAALAL
HCCHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
RENMGARVTASHTTAMHSYNGAYTSRLFRLLKLSGINFVANPLVNIHLQGRFDTYPKRRG
HHCCCCEEEECCHHHHHCCCCHHHHHHHHHHHHCCCCEEECCEEEEEEECCCCCCCHHCC
ITRVKEMLAAEINVCFGHDDVFDPWYPLGTANMLQVLHMGLHICQLMGYEQINDGLNLIT
HHHHHHHHHHHHHEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHCCCCCEEE
THSAKTLNLADYGLQPGNRANLIILPAENGFDALRRQVPVSYSIRHGVVIAKTQPAESRI
ECCCCEEEHHHCCCCCCCCCCEEEEECCCCHHHHHHCCCCEEEECCCEEEEECCCCCCEE
YLGQEEIVDFRR
EECHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1640834; 8450832; 9278503 [H]