Click here to switch to the map view.

The map label for this gene is fdoG [H]

Identifier: 170022300

GI number: 170022300

Start: 40846

End: 43257

Strand: Direct

Name: fdoG [H]

Synonym: YPK_0038

Alternate gene names: 170022300

Gene position: 40846-43257 (Clockwise)

Preceding gene: 170022299

Following gene: 170022301

Centisome position: 0.87

GC content: 51.66

Gene sequence:

>2412_bases
ATGACCAACCACTGGGTTGACATTAAGAACGCGGATTTAATTATCGTCATGGGCGGTAATGCGGCAGAAGCGCATCCGGT
GGGGTTCCGCTGGGCGATGGAAGCCAAAATCCACAACAATGCCAAGCTTCTGGTGATAGATCCGCGCTTTACTCGTACGG
CATCGGTGGCTGATTTCTATACGCCAATCCGCTCCGGTACGGATATTGCGTTTCTGTCCGGTGTCTTGTTGTACCTGATC
TCCAACAATAAAATTAACCGTGAATATGTCGAAGCCTATACCAACGCCAGCTTGCTGGTGCGGGAAGACTATGCTTTCGA
TGATGGCCTGTTCAGTGGCTATGACGCCGAAAACCGTAAATACGATAAAACCAGCTGGAACTATCAGTTGGATGAAGACG
GTTTTGCTAAACGGGATGTCACGCTGCAACACCCGCGTTGTGTGTGGAACCTGCTGAAAGAGCACGTTAGCCGCTATACA
CCGGAAGTGGTCTCCAATATTTGCGGTACGCCAAAAGACGATTTCCTGCAGGTTTGTGAATATCTCGCCGAAACCAGTGT
ATCCAATAAAACGGCGACGTTCCTGTATGCCTTGGGTTGGACGCAGCACTCTGTGGGTGCGCAGAATATCCGTACTATGG
CGATGATCCAGTTGCTGTTGGGCAACATGGGGATGGCAGGTGGCGGTATTAACGCCCTACGCGGTCACTCCAATATCCAA
GGGCTGACTGACCTTGGCCTGTTGTCGCAAAGCCTGCCGGGTTACTTGAACTTGCCGTCAGAAAAACAGCCGGATATTGA
TACCTACCTGAAGGCCAACACGCCGAAAACCCTGTTACCAGGCCAGGTTAACTACTGGAGTAATTACCCGAAATTCTTTG
TCAGTTTGATGAAAAGTTTCTACGGTGATAACGCCCAAAAGGAAAATGGCTGGGGCTATGACTGGCTGCCGAAGTGGGAT
AAAGGCTACGACGTCTTGCAGTATTTCGAAATGATGTCGCAGGGCAAGGTCAATGGCTATCTGTGCCAAGGCTTTAACCC
GATTGCCTCGTTCCCGGATAAAAACAAAGTGACAGCGGCGCTGTCGAAGCTGAAATTCTTGGTGACGATTGATCCACTCA
ATACTGAAACCGCGAATTTCTGGCAAAACCACGGTGAATTTAACGATGTCGATCCATCGAAAATTCAAACTGAGGTGTTC
CGCTTGCCATCCAGTTGTTTTGCTGAAGAGAACGGCTCGATCGTTAACTCCAGCCGCTGGCTGCAATGGCACTGGAAAGG
CGCTGATTCACCGGGAGAAGCACTGAACGATGGTGCAATTCTGGCGGGCATCTTTATGCGTATGCGTGAGATGTACCAGC
GGGAAGGTGGCGCGGTGCCTGAGCAGGTGCTCAATATGACCTGGGACTACCTGACACCAGAAAATCCAGAGCCGGAAGAA
GTGGCAATGGAAAGTAATGGGCGAGCGCTGGCGGATCTCACTGATGCCGACGGCAAAGTGTTGGTCAAAAAAGGCGAACA
GCTCAGTACCTTCGCTCAACTGCGTGATGACGGTACCACTTCCAGTGGTTGCTGGATCTTTGCGGGTAGCTGGACACCGG
CCGGTAACCAAATGGCGCGGCGTGATAATGCGGATCCATCGGGTCTCGGCAATACCTTGGGCTGGGCCTGGGCATGGCCG
CTTAACCGCCGCATTCTGTACAACCGTGCGTCTGCTGACCCGCAGGGTAAACCGTGGGATCCGAAACGCCAGTTGCTGGA
GTGGGATGGTGCTAAGTGGGCCGGTATTGATGTTGCTGACTACAGTGCTGCGGCACCGGGCAGTGATGTTGGGCCGTTTA
TCATGCAGCCTGAAGGGATGGGCCGTTTGTTTGCAATCGATAAGATGGCTGAAGGGCCGTTCCCTGAGCATTATGAGCCA
TTTGAAACGCCGTTGGGGACCAACCCGCTGCATCCGAATGTGATCTCTAACCCAGCCGCTCGTGTATTTAAAGATGATCT
GGCCGCGATGGGGTCGCACGAGCAATTCCCTTATGTTGGCACCACTTATCGTTTAACCGAACATTTCCACTACTGGACCA
AACATGCGTTGCTCAATGCCATCGCTCAACCGGAACAGTTTGTGGAAATTGGCGAAAAACTGGCGGCGAAGAAAGGGATT
AAGCAAGGCGATACGGTGAAAGTCAGCTCTAACCGTGGCTTTATCAAAGCCAAGGCGGTGGTGACTAAACGTATTCGTAC
TCTGAATGTTCATGGGCAAGAAGTTGACACCATTGGTATTCCGATCCATTGGGGATACGAAGGGGTGGCAAAAAAAGGCT
TCCTGGCGAATACCCTGACACCGTATGTCGGTGATGCCAATACGCAAACGCCAGAGTTCAAGGCGTTTCTGGTCAATGTG
GAAAAGGTGTAA

Upstream 100 bases:

>100_bases
ATTTAGTCGCGCTCTCGGCATGCTTGCCGTAGACAACCAAGCACGTGTCTGACACGGACCAACGGTAGCAAGTCTTGCTC
CAACATTTGGTCGCGGTGCG

Downstream 100 bases:

>100_bases
CGGAGAGAATCTATGTCACTGCAAACTCAAGACATTATCCGGCGCTCCGGTACTAATTCCCTTACGCCGCCACCTCAGGT
CCGTGATCATCAGGAACCGG

Product: formate dehydrogenase subunit alpha

Products: NA

Alternate protein names: Aerobic formate dehydrogenase major subunit; FDH-Z subunit alpha; Formate dehydrogenase-O subunit alpha [H]

Number of amino acids: Translated: 803; Mature: 802

Protein sequence:

>803_residues
MTNHWVDIKNADLIIVMGGNAAEAHPVGFRWAMEAKIHNNAKLLVIDPRFTRTASVADFYTPIRSGTDIAFLSGVLLYLI
SNNKINREYVEAYTNASLLVREDYAFDDGLFSGYDAENRKYDKTSWNYQLDEDGFAKRDVTLQHPRCVWNLLKEHVSRYT
PEVVSNICGTPKDDFLQVCEYLAETSVSNKTATFLYALGWTQHSVGAQNIRTMAMIQLLLGNMGMAGGGINALRGHSNIQ
GLTDLGLLSQSLPGYLNLPSEKQPDIDTYLKANTPKTLLPGQVNYWSNYPKFFVSLMKSFYGDNAQKENGWGYDWLPKWD
KGYDVLQYFEMMSQGKVNGYLCQGFNPIASFPDKNKVTAALSKLKFLVTIDPLNTETANFWQNHGEFNDVDPSKIQTEVF
RLPSSCFAEENGSIVNSSRWLQWHWKGADSPGEALNDGAILAGIFMRMREMYQREGGAVPEQVLNMTWDYLTPENPEPEE
VAMESNGRALADLTDADGKVLVKKGEQLSTFAQLRDDGTTSSGCWIFAGSWTPAGNQMARRDNADPSGLGNTLGWAWAWP
LNRRILYNRASADPQGKPWDPKRQLLEWDGAKWAGIDVADYSAAAPGSDVGPFIMQPEGMGRLFAIDKMAEGPFPEHYEP
FETPLGTNPLHPNVISNPAARVFKDDLAAMGSHEQFPYVGTTYRLTEHFHYWTKHALLNAIAQPEQFVEIGEKLAAKKGI
KQGDTVKVSSNRGFIKAKAVVTKRIRTLNVHGQEVDTIGIPIHWGYEGVAKKGFLANTLTPYVGDANTQTPEFKAFLVNV
EKV

Sequences:

>Translated_803_residues
MTNHWVDIKNADLIIVMGGNAAEAHPVGFRWAMEAKIHNNAKLLVIDPRFTRTASVADFYTPIRSGTDIAFLSGVLLYLI
SNNKINREYVEAYTNASLLVREDYAFDDGLFSGYDAENRKYDKTSWNYQLDEDGFAKRDVTLQHPRCVWNLLKEHVSRYT
PEVVSNICGTPKDDFLQVCEYLAETSVSNKTATFLYALGWTQHSVGAQNIRTMAMIQLLLGNMGMAGGGINALRGHSNIQ
GLTDLGLLSQSLPGYLNLPSEKQPDIDTYLKANTPKTLLPGQVNYWSNYPKFFVSLMKSFYGDNAQKENGWGYDWLPKWD
KGYDVLQYFEMMSQGKVNGYLCQGFNPIASFPDKNKVTAALSKLKFLVTIDPLNTETANFWQNHGEFNDVDPSKIQTEVF
RLPSSCFAEENGSIVNSSRWLQWHWKGADSPGEALNDGAILAGIFMRMREMYQREGGAVPEQVLNMTWDYLTPENPEPEE
VAMESNGRALADLTDADGKVLVKKGEQLSTFAQLRDDGTTSSGCWIFAGSWTPAGNQMARRDNADPSGLGNTLGWAWAWP
LNRRILYNRASADPQGKPWDPKRQLLEWDGAKWAGIDVADYSAAAPGSDVGPFIMQPEGMGRLFAIDKMAEGPFPEHYEP
FETPLGTNPLHPNVISNPAARVFKDDLAAMGSHEQFPYVGTTYRLTEHFHYWTKHALLNAIAQPEQFVEIGEKLAAKKGI
KQGDTVKVSSNRGFIKAKAVVTKRIRTLNVHGQEVDTIGIPIHWGYEGVAKKGFLANTLTPYVGDANTQTPEFKAFLVNV
EKV
>Mature_802_residues
TNHWVDIKNADLIIVMGGNAAEAHPVGFRWAMEAKIHNNAKLLVIDPRFTRTASVADFYTPIRSGTDIAFLSGVLLYLIS
NNKINREYVEAYTNASLLVREDYAFDDGLFSGYDAENRKYDKTSWNYQLDEDGFAKRDVTLQHPRCVWNLLKEHVSRYTP
EVVSNICGTPKDDFLQVCEYLAETSVSNKTATFLYALGWTQHSVGAQNIRTMAMIQLLLGNMGMAGGGINALRGHSNIQG
LTDLGLLSQSLPGYLNLPSEKQPDIDTYLKANTPKTLLPGQVNYWSNYPKFFVSLMKSFYGDNAQKENGWGYDWLPKWDK
GYDVLQYFEMMSQGKVNGYLCQGFNPIASFPDKNKVTAALSKLKFLVTIDPLNTETANFWQNHGEFNDVDPSKIQTEVFR
LPSSCFAEENGSIVNSSRWLQWHWKGADSPGEALNDGAILAGIFMRMREMYQREGGAVPEQVLNMTWDYLTPENPEPEEV
AMESNGRALADLTDADGKVLVKKGEQLSTFAQLRDDGTTSSGCWIFAGSWTPAGNQMARRDNADPSGLGNTLGWAWAWPL
NRRILYNRASADPQGKPWDPKRQLLEWDGAKWAGIDVADYSAAAPGSDVGPFIMQPEGMGRLFAIDKMAEGPFPEHYEPF
ETPLGTNPLHPNVISNPAARVFKDDLAAMGSHEQFPYVGTTYRLTEHFHYWTKHALLNAIAQPEQFVEIGEKLAAKKGIK
QGDTVKVSSNRGFIKAKAVVTKRIRTLNVHGQEVDTIGIPIHWGYEGVAKKGFLANTLTPYVGDANTQTPEFKAFLVNVE
KV

Specific function: Allows to use formate as major electron donor during aerobic respiration. Subunit alpha possibly forms the active site [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI3868720, Length=804, Percent_Identity=83.955223880597, Blast_Score=1454, Evalue=0.0,
Organism=Escherichia coli, GI3868719, Length=803, Percent_Identity=76.587795765878, Blast_Score=1336, Evalue=0.0,
Organism=Escherichia coli, GI3868721, Length=448, Percent_Identity=23.6607142857143, Blast_Score=122, Evalue=1e-28,
Organism=Escherichia coli, GI87081797, Length=264, Percent_Identity=27.2727272727273, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1787870, Length=236, Percent_Identity=28.8135593220339, Blast_Score=80, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006443
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR006655
- InterPro:   IPR006311 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: =1.2.1.2 [H]

Molecular weight: Translated: 89650; Mature: 89519

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: PS00932 MOLYBDOPTERIN_PROK_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNHWVDIKNADLIIVMGGNAAEAHPVGFRWAMEAKIHNNAKLLVIDPRFTRTASVADFY
CCCCEEEECCCCEEEEECCCCCCCCCCCEEEEEEEEECCCCEEEEECCCCCCCCHHHHHH
TPIRSGTDIAFLSGVLLYLISNNKINREYVEAYTNASLLVREDYAFDDGLFSGYDAENRK
HHHCCCCCHHHHHHHHHEEECCCCCCHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCC
YDKTSWNYQLDEDGFAKRDVTLQHPRCVWNLLKEHVSRYTPEVVSNICGTPKDDFLQVCE
CCCCCCCEEECCCCCCCCCCEECCHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHH
YLAETSVSNKTATFLYALGWTQHSVGAQNIRTMAMIQLLLGNMGMAGGGINALRGHSNIQ
HHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCC
GLTDLGLLSQSLPGYLNLPSEKQPDIDTYLKANTPKTLLPGQVNYWSNYPKFFVSLMKSF
CHHHHHHHHHCCCCCCCCCCCCCCCHHHEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHH
YGDNAQKENGWGYDWLPKWDKGYDVLQYFEMMSQGKVNGYLCQGFNPIASFPDKNKVTAA
HCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCHHHCCCCCCHHHHH
LSKLKFLVTIDPLNTETANFWQNHGEFNDVDPSKIQTEVFRLPSSCFAEENGSIVNSSRW
HHHEEEEEEECCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHCCCCCEEECCCE
LQWHWKGADSPGEALNDGAILAGIFMRMREMYQREGGAVPEQVLNMTWDYLTPENPEPEE
EEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHCHHHCCCCCCCCHHH
VAMESNGRALADLTDADGKVLVKKGEQLSTFAQLRDDGTTSSGCWIFAGSWTPAGNQMAR
HHHCCCCCEEEEECCCCCEEEEECCCHHHHHHHHHCCCCCCCCEEEEECCCCCCCCHHHH
RDNADPSGLGNTLGWAWAWPLNRRILYNRASADPQGKPWDPKRQLLEWDGAKWAGIDVAD
CCCCCCCCCCCCCCEEEECCCCCEEEEECCCCCCCCCCCCHHHHHHHCCCCEEECCEECC
YSAAAPGSDVGPFIMQPEGMGRLFAIDKMAEGPFPEHYEPFETPLGTNPLHPNVISNPAA
CCCCCCCCCCCCEEECCCCCCEEEEEEHHCCCCCCCCCCCCCCCCCCCCCCCCHHCCHHH
RVFKDDLAAMGSHEQFPYVGTTYRLTEHFHYWTKHALLNAIAQPEQFVEIGEKLAAKKGI
HHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCC
KQGDTVKVSSNRGFIKAKAVVTKRIRTLNVHGQEVDTIGIPIHWGYEGVAKKGFLANTLT
CCCCEEEEECCCCEEEHHHHHHHHHHEEECCCCEEEEEEEEEECCCHHHHCCCCHHHCCC
PYVGDANTQTPEFKAFLVNVEKV
CCCCCCCCCCCCEEEEEEEEECC
>Mature Secondary Structure 
TNHWVDIKNADLIIVMGGNAAEAHPVGFRWAMEAKIHNNAKLLVIDPRFTRTASVADFY
CCCEEEECCCCEEEEECCCCCCCCCCCEEEEEEEEECCCCEEEEECCCCCCCCHHHHHH
TPIRSGTDIAFLSGVLLYLISNNKINREYVEAYTNASLLVREDYAFDDGLFSGYDAENRK
HHHCCCCCHHHHHHHHHEEECCCCCCHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCC
YDKTSWNYQLDEDGFAKRDVTLQHPRCVWNLLKEHVSRYTPEVVSNICGTPKDDFLQVCE
CCCCCCCEEECCCCCCCCCCEECCHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHH
YLAETSVSNKTATFLYALGWTQHSVGAQNIRTMAMIQLLLGNMGMAGGGINALRGHSNIQ
HHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCC
GLTDLGLLSQSLPGYLNLPSEKQPDIDTYLKANTPKTLLPGQVNYWSNYPKFFVSLMKSF
CHHHHHHHHHCCCCCCCCCCCCCCCHHHEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHH
YGDNAQKENGWGYDWLPKWDKGYDVLQYFEMMSQGKVNGYLCQGFNPIASFPDKNKVTAA
HCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCHHHCCCCCCHHHHH
LSKLKFLVTIDPLNTETANFWQNHGEFNDVDPSKIQTEVFRLPSSCFAEENGSIVNSSRW
HHHEEEEEEECCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHCCCCCEEECCCE
LQWHWKGADSPGEALNDGAILAGIFMRMREMYQREGGAVPEQVLNMTWDYLTPENPEPEE
EEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHCHHHCCCCCCCCHHH
VAMESNGRALADLTDADGKVLVKKGEQLSTFAQLRDDGTTSSGCWIFAGSWTPAGNQMAR
HHHCCCCCEEEEECCCCCEEEEECCCHHHHHHHHHCCCCCCCCEEEEECCCCCCCCHHHH
RDNADPSGLGNTLGWAWAWPLNRRILYNRASADPQGKPWDPKRQLLEWDGAKWAGIDVAD
CCCCCCCCCCCCCCEEEECCCCCEEEEECCCCCCCCCCCCHHHHHHHCCCCEEECCEECC
YSAAAPGSDVGPFIMQPEGMGRLFAIDKMAEGPFPEHYEPFETPLGTNPLHPNVISNPAA
CCCCCCCCCCCCEEECCCCCCEEEEEEHHCCCCCCCCCCCCCCCCCCCCCCCCHHCCHHH
RVFKDDLAAMGSHEQFPYVGTTYRLTEHFHYWTKHALLNAIAQPEQFVEIGEKLAAKKGI
HHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCC
KQGDTVKVSSNRGFIKAKAVVTKRIRTLNVHGQEVDTIGIPIHWGYEGVAKKGFLANTLT
CCCCEEEEECCCCEEEHHHHHHHHHHEEECCCCEEEEEEEEEECCCHHHHCCCCHHHCCC
PYVGDANTQTPEFKAFLVNVEKV
CCCCCCCCCCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8346018; 9278503; 8522521 [H]