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The map label for this gene is avtA [H]

Identifier: 170022276

GI number: 170022276

Start: 15272

End: 16642

Strand: Reverse

Name: avtA [H]

Synonym: YPK_0014

Alternate gene names: 170022276

Gene position: 16642-15272 (Counterclockwise)

Preceding gene: 170022277

Following gene: 170022272

Centisome position: 0.35

GC content: 47.85

Gene sequence:

>1371_bases
ATGGCGATATTTTCACGCAGTCAGAAGAAATTCTTCCGCATTGCGTCCGCTTTTATCTGCGAGTATGGTACTTGTTCACT
TACAGATAACAATACATTTTCATTTATGAAGTTTTCACTTTTCGGCGACAAATTTACCCGTTATGCGGGTATTACCAGAT
TGATGGATGACCTCAACGATGGCCTGAGAACACCGGGTTCTATCATGCTTGGTGGCGGAAATCCGGCACATATCCCTGAG
ATGGATACCTACTTCCAACAACTGTGTCAGGAGATGCTAACAGAAGGCAAGTTAACCGAGGCATTGTGTAATTACGACGG
GCCGCAAGGTAAAGACTTACTGCTAAACGCACTGGCAAAAATGCTGCGCGATGAGCTGGGTTGGCAGATAGAGCCACAGA
ATATTGCACTGACAAATGGCAGTCAGAGTGCATTTTTCTACTTATTTAATTTGTTCGCTGGCCGTTATGCCGATGGTAGC
CGCCGTCGGGTGCTGTTCCCACTGGCGCCAGAGTATCTGGGCTATGCGGATGCAGGTCTGGATGAAGATTTATTTGTCTC
CGCCAAACCGAATATTGAGCTGTTACCCGAGGGGCAGTTTAAATATCACGTGGATTTTGAACACCTCAATATTACTGATG
ATATTGGCTTGATATGCGTATCAAGGCCCACAAACCCCACCGGTAATGTCATTACTGACGAAGAGTTAATCCGCCTTGAT
GCTATCACGCAGCAACGTAATATTCCGTTATTGATTGATAATGCTTATGGCGTCCCCTTCCCTGGTATTATTTTTACCGA
CGCCACACCGCTGTGGAACCCGAACATCATCTTGTGCATGAGCCTGTCAAAACTGGGCCTACCAGGTTCACGATGCGGGA
TTGTCATTGCCGATGAAAAAGTGATTTCGGCCATCACCAATATGAACGGTATTATCAGCCTGTCACCGGGCGGTATGGGG
CCCGCGATCGCCGCCGAAATGATTGAGCGTGGTGATTTATTGCGCTTATCCAACGAGGTGATCCGGCCGTTTTACTTTGA
ACGTGTACAGCAGACCATCGCCATCTTGCGCAAATACCTGCCCGCTGAACGCTGCCTGATCCACAAACCCGAAGGCGCTA
TTTTCCTCTGGCTGTGGTTTAAAGATTTGCCAATCAGCACCGAACTGCTCTATCAGCGCCTGAAAAAACGTGGTGTTCTG
ATGGTACCGGGCCATTACTTCTTCCCCGGTCTGGGCTATGACTGGCCACATACTCACCAATGTATGCGAATGAATTATGT
GCCGGCTCCGGAAATGATTGAAAAAGGTGTCGCGATCTTGGCGGAAGAGATTGAACGAGCGTTTCAGGAAGCGAAACAAC
TTACTGATTAA

Upstream 100 bases:

>100_bases
CCCTTACTCCTTAGAAAAAAAGGTTAATTCTCTCCTCTTGCCATTTCATGGTTTTTTACTTTTTTAGCTATATTAGTTTA
TTATCCCGTCCTGAATATGA

Downstream 100 bases:

>100_bases
TAAATATACTGTTAACTCGCCAACAGAGTGAATCGCCGTTACCCCCTTCACCAATACAAACAGGGCAGCCAATTACGCTG
CCCTGAAGTTTAATAGCCCG

Product: valine--pyruvate transaminase

Products: NA

Alternate protein names: Alanine--valine transaminase; Transaminase C [H]

Number of amino acids: Translated: 456; Mature: 455

Protein sequence:

>456_residues
MAIFSRSQKKFFRIASAFICEYGTCSLTDNNTFSFMKFSLFGDKFTRYAGITRLMDDLNDGLRTPGSIMLGGGNPAHIPE
MDTYFQQLCQEMLTEGKLTEALCNYDGPQGKDLLLNALAKMLRDELGWQIEPQNIALTNGSQSAFFYLFNLFAGRYADGS
RRRVLFPLAPEYLGYADAGLDEDLFVSAKPNIELLPEGQFKYHVDFEHLNITDDIGLICVSRPTNPTGNVITDEELIRLD
AITQQRNIPLLIDNAYGVPFPGIIFTDATPLWNPNIILCMSLSKLGLPGSRCGIVIADEKVISAITNMNGIISLSPGGMG
PAIAAEMIERGDLLRLSNEVIRPFYFERVQQTIAILRKYLPAERCLIHKPEGAIFLWLWFKDLPISTELLYQRLKKRGVL
MVPGHYFFPGLGYDWPHTHQCMRMNYVPAPEMIEKGVAILAEEIERAFQEAKQLTD

Sequences:

>Translated_456_residues
MAIFSRSQKKFFRIASAFICEYGTCSLTDNNTFSFMKFSLFGDKFTRYAGITRLMDDLNDGLRTPGSIMLGGGNPAHIPE
MDTYFQQLCQEMLTEGKLTEALCNYDGPQGKDLLLNALAKMLRDELGWQIEPQNIALTNGSQSAFFYLFNLFAGRYADGS
RRRVLFPLAPEYLGYADAGLDEDLFVSAKPNIELLPEGQFKYHVDFEHLNITDDIGLICVSRPTNPTGNVITDEELIRLD
AITQQRNIPLLIDNAYGVPFPGIIFTDATPLWNPNIILCMSLSKLGLPGSRCGIVIADEKVISAITNMNGIISLSPGGMG
PAIAAEMIERGDLLRLSNEVIRPFYFERVQQTIAILRKYLPAERCLIHKPEGAIFLWLWFKDLPISTELLYQRLKKRGVL
MVPGHYFFPGLGYDWPHTHQCMRMNYVPAPEMIEKGVAILAEEIERAFQEAKQLTD
>Mature_455_residues
AIFSRSQKKFFRIASAFICEYGTCSLTDNNTFSFMKFSLFGDKFTRYAGITRLMDDLNDGLRTPGSIMLGGGNPAHIPEM
DTYFQQLCQEMLTEGKLTEALCNYDGPQGKDLLLNALAKMLRDELGWQIEPQNIALTNGSQSAFFYLFNLFAGRYADGSR
RRVLFPLAPEYLGYADAGLDEDLFVSAKPNIELLPEGQFKYHVDFEHLNITDDIGLICVSRPTNPTGNVITDEELIRLDA
ITQQRNIPLLIDNAYGVPFPGIIFTDATPLWNPNIILCMSLSKLGLPGSRCGIVIADEKVISAITNMNGIISLSPGGMGP
AIAAEMIERGDLLRLSNEVIRPFYFERVQQTIAILRKYLPAERCLIHKPEGAIFLWLWFKDLPISTELLYQRLKKRGVLM
VPGHYFFPGLGYDWPHTHQCMRMNYVPAPEMIEKGVAILAEEIERAFQEAKQLTD

Specific function: Unknown

COG id: COG3977

COG function: function code E; Alanine-alpha-ketoisovalerate (or valine-pyruvate) aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI48994949, Length=416, Percent_Identity=79.0865384615385, Blast_Score=701, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.66 [H]

Molecular weight: Translated: 51325; Mature: 51194

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIFSRSQKKFFRIASAFICEYGTCSLTDNNTFSFMKFSLFGDKFTRYAGITRLMDDLND
CCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHH
GLRTPGSIMLGGGNPAHIPEMDTYFQQLCQEMLTEGKLTEALCNYDGPQGKDLLLNALAK
HHCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHHHH
MLRDELGWQIEPQNIALTNGSQSAFFYLFNLFAGRYADGSRRRVLFPLAPEYLGYADAGL
HHHHHHCCEECCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCEEEEECCHHHCCCCCCCC
DEDLFVSAKPNIELLPEGQFKYHVDFEHLNITDDIGLICVSRPTNPTGNVITDEELIRLD
CCCEEEECCCCEEEEECCCEEEEEEEEEEEECCCCCEEEEECCCCCCCCEECHHHHHHHH
AITQQRNIPLLIDNAYGVPFPGIIFTDATPLWNPNIILCMSLSKLGLPGSRCGIVIADEK
HHHHCCCCCEEEECCCCCCCCCEEEECCCCCCCCCEEEEEEHHHCCCCCCCCEEEEECHH
VISAITNMNGIISLSPGGMGPAIAAEMIERGDLLRLSNEVIRPFYFERVQQTIAILRKYL
HHHHHHCCCCEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PAERCLIHKPEGAIFLWLWFKDLPISTELLYQRLKKRGVLMVPGHYFFPGLGYDWPHTHQ
CHHHHEEECCCCCEEEEEEEECCCCCHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCH
CMRMNYVPAPEMIEKGVAILAEEIERAFQEAKQLTD
HHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AIFSRSQKKFFRIASAFICEYGTCSLTDNNTFSFMKFSLFGDKFTRYAGITRLMDDLND
CCCCCHHHHHHHHHHHHHHCCCEEEECCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHH
GLRTPGSIMLGGGNPAHIPEMDTYFQQLCQEMLTEGKLTEALCNYDGPQGKDLLLNALAK
HHCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHHHH
MLRDELGWQIEPQNIALTNGSQSAFFYLFNLFAGRYADGSRRRVLFPLAPEYLGYADAGL
HHHHHHCCEECCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCEEEEECCHHHCCCCCCCC
DEDLFVSAKPNIELLPEGQFKYHVDFEHLNITDDIGLICVSRPTNPTGNVITDEELIRLD
CCCEEEECCCCEEEEECCCEEEEEEEEEEEECCCCCEEEEECCCCCCCCEECHHHHHHHH
AITQQRNIPLLIDNAYGVPFPGIIFTDATPLWNPNIILCMSLSKLGLPGSRCGIVIADEK
HHHHCCCCCEEEECCCCCCCCCEEEECCCCCCCCCEEEEEEHHHCCCCCCCCEEEEECHH
VISAITNMNGIISLSPGGMGPAIAAEMIERGDLLRLSNEVIRPFYFERVQQTIAILRKYL
HHHHHHCCCCEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PAERCLIHKPEGAIFLWLWFKDLPISTELLYQRLKKRGVLMVPGHYFFPGLGYDWPHTHQ
CHHHHEEECCCCCEEEEEEEECCCCCHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCH
CMRMNYVPAPEMIEKGVAILAEEIERAFQEAKQLTD
HHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2825136; 8041620; 9278503 [H]