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The map label for this gene is hrcA [H]

Identifier: 169834466

GI number: 169834466

Start: 574701

End: 575735

Strand: Direct

Name: hrcA [H]

Synonym: SPH_0622

Alternate gene names: 169834466

Gene position: 574701-575735 (Clockwise)

Preceding gene: 169832876

Following gene: 169832954

Centisome position: 25.59

GC content: 43.77

Gene sequence:

>1035_bases
ATGGTTACAGAGCGTCAGCAGGATATTTTAAATCTGATTATTGACATCTTTACCAAAACGCACGAACCTGTCGGATCAAA
AGCCTTGCAAGAGTCTATTAACTCTAGCAGTGCAACCATTCGTAATGACATGGCGGAACTAGAAAAACAAGGGTTGCTTG
AGAAGGCTCATACTTCAAGCGGTCGGATGCCAAGTGTTGCTGGTTTTCAGTACTATGTGAAACACTCACTGGATTTTGAC
CGGCTGGCTGAAAATGAGGTATATGAGATTGTCAAAGCCTTTGATCAGGAATTCTTCAAATTGGAGGATATTCTGCAAGA
GGCTGCTAACTTACTAACAGACCTGAGTGGCTGTACGGTAGTGGCACTGGATGTTGAGCCGAGCAGGCAACGTTTGACAG
CCTTTGATATCGTTGTTTTGGGGCAACATACAGCCTTGGCGGTATTTACCCTAGACGAGTCGCGAACGGTTACTAGTCAG
TTTCTGATTCCAAGGAACTTCTTGCAGGAGGATTTGCTGAAACTGAAGAGCATCATTCAGGAACGTTTCCTCGGTCACAC
CGTTTTAGATATTCACTACAAGATTCGGACGGAGATTCCGCAGATTATCCAGCGTTACTTTACAACAACGGATAATGTCA
TCGATCTCTTTGAACACATCTTTAAGGAAATGTTCAACGAAAACATTGTGATGGCGGGCAAGGTCCATCTCTTGAATTTT
GCCAATCTAGCAGCCTATCAGTTCTTTGACCAACCGCAAAAGGTGGCCTTGGAGATTCGTGAGGGGTTGCGTGAGGAACA
GATGCAAAATGTTCGTGTTGCAGACGGTCAAGAGTCCTGTTTAGCTGACCTAGCGGTGATTAGTAGTAAGTTCCTCATTC
CTTATCGGGGAGTTGGAATTCTAGCCATTATCGGTCCAGTTAATCTGGATTACCAACAGCTAATCAATCAAGTCAATGTG
GTCAACCGTGTTTTGACTATGAAGTTGACAGATTTTTACCGCTACCTCAGCAGTAATCATTATGAAGTACATTAA

Upstream 100 bases:

>100_bases
TTTTTGTCTTGACATTCTCTTCTAAGGGTGTATAATAGAATCATAAGTTAGCACTTGGATGCATTGAGTGCTAATTGATC
AGACAGAGAGGAGTGATGAG

Downstream 100 bases:

>100_bases
GATTGAAATCATTAAAGGAGGCGAACATGGCCCAAGATATAAAAAATGAAGAAGTAGAAGAAGTTCAAGAAGAGGAAGTT
GTGGAAACAGCTGAAGAAAC

Product: heat-inducible transcription repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDMAELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFD
RLAENEVYEIVKAFDQEFFKLEDILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFEHIFKEMFNENIVMAGKVHLLNF
ANLAAYQFFDQPQKVALEIREGLREEQMQNVRVADGQESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQVNV
VNRVLTMKLTDFYRYLSSNHYEVH

Sequences:

>Translated_344_residues
MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDMAELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFD
RLAENEVYEIVKAFDQEFFKLEDILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFEHIFKEMFNENIVMAGKVHLLNF
ANLAAYQFFDQPQKVALEIREGLREEQMQNVRVADGQESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQVNV
VNRVLTMKLTDFYRYLSSNHYEVH
>Mature_344_residues
MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDMAELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFD
RLAENEVYEIVKAFDQEFFKLEDILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFEHIFKEMFNENIVMAGKVHLLNF
ANLAAYQFFDQPQKVALEIREGLREEQMQNVRVADGQESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQVNV
VNRVLTMKLTDFYRYLSSNHYEVH

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons [H]

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001034
- InterPro:   IPR005104
- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991 [H]

Pfam domain/function: PF03444 DUF293; PF01628 HrcA [H]

EC number: NA

Molecular weight: Translated: 39392; Mature: 39392

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDMAELEKQGLLEKAHTSS
CCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCC
GRMPSVAGFQYYVKHSLDFDRLAENEVYEIVKAFDQEFFKLEDILQEAANLLTDLSGCTV
CCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
VALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQFLIPRNFLQEDLLKLKSIIQ
EEEECCCCHHHHHHHHEEEECCCCEEEEEEECCCCHHHHHHHCCHHHHHHHHHHHHHHHH
ERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFEHIFKEMFNENIVMAGKVHLLNF
HHHCCCEEEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEECHHHHHHH
ANLAAYQFFDQPQKVALEIREGLREEQMQNVRVADGQESCLADLAVISSKFLIPYRGVGI
HHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEE
LAIIGPVNLDYQQLINQVNVVNRVLTMKLTDFYRYLSSNHYEVH
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDMAELEKQGLLEKAHTSS
CCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCC
GRMPSVAGFQYYVKHSLDFDRLAENEVYEIVKAFDQEFFKLEDILQEAANLLTDLSGCTV
CCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
VALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQFLIPRNFLQEDLLKLKSIIQ
EEEECCCCHHHHHHHHEEEECCCCEEEEEEECCCCHHHHHHHCCHHHHHHHHHHHHHHHH
ERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFEHIFKEMFNENIVMAGKVHLLNF
HHHCCCEEEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEECHHHHHHH
ANLAAYQFFDQPQKVALEIREGLREEQMQNVRVADGQESCLADLAVISSKFLIPYRGVGI
HHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEE
LAIIGPVNLDYQQLINQVNVVNRVLTMKLTDFYRYLSSNHYEVH
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA