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The map label for this gene is tenA [H]

Identifier: 169834328

GI number: 169834328

Start: 755746

End: 756438

Strand: Direct

Name: tenA [H]

Synonym: SPH_0809

Alternate gene names: 169834328

Gene position: 755746-756438 (Clockwise)

Preceding gene: 169833801

Following gene: 169832871

Centisome position: 33.65

GC content: 39.25

Gene sequence:

>693_bases
ATGGAATTTACAGATATTGCGATGGAATTATCCAAGAAAGCTTGGCAGGCTTCCTTTCATCATCCCTTTATTTTACAATT
ACAAGAGGGGAATTTAGAACCTGCCATTTTCCGCTATTACCTGATTCAGGATGCCTACTATCTGAAGGCTTTCTCAGAAA
TCTATCATCTGTTGGCTGATAAGACTTCAAACCAAGAGATGAAAAGACTCTTGAAACAAAATGCTCAGGGTTTAGTGGAG
GGTGAGTTATTTATTCGCCAACAATTTTTCAAGGAATTGGAAATCAACGACCAGGAAATGGAGCAACATCCAATCGCTCC
AACCTGTTATCATTACATTTCTCATATTTATAGGCAATTTGCAGAACCGAACTTAGCCATAGCTTTTGCAAGCTTGCTTC
CTTGTCCTTGGTTATACCATGATATAGGCAAATCACTTAATCTTAAACCATCACCAAATCCTCTCTATCAACAATGGATT
GAAACTTATATTACGGATGAGTTAGAGCAACAGATCAGAGAGGAGGGAGCACTGGTCAATCAGCTCTATCGAGAAAGTGA
TGAGACAGATAAGCAAAAAATGCTAGATGCCTTCCACATCAGTGTTCATATGGAAGCCAAGTTTTGGGAGATGGCTTACC
AACACCAGACATGGAAGAGCGATTTACAGTCTTTAGAAAAAGGAGAAGAATAG

Upstream 100 bases:

>100_bases
AATAGCTATCGGACTTTTTATATTCCTAAAAAAACAAAATTAATCTACCTGCTTTTCTTTTTATTGCTTCAAACCAGTCT
ATTTTTATAAAGGAGTTATT

Downstream 100 bases:

>100_bases
AAACATGAGAAAGCACCAACTACAAGTTCACAAATTGACCATTTTATCTATGATGATTGCCCTTGATGTAGTCCTTACAC
CTATCTTTCGGATTGAGGGA

Product: TENA/THI-4 family protein

Products: NA

Alternate protein names: Thiaminase II; Transcriptional activator tenA [H]

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQDAYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVE
GELFIRQQFFKELEINDQEMEQHPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTWKSDLQSLEKGEE

Sequences:

>Translated_230_residues
MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQDAYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVE
GELFIRQQFFKELEINDQEMEQHPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTWKSDLQSLEKGEE
>Mature_230_residues
MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQDAYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVE
GELFIRQQFFKELEINDQEMEQHPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTWKSDLQSLEKGEE

Specific function: Stimulates the production of several extracellular degradative enzymes at the transcriptional level, probably by interfering with degS and degU, which are required for this effect. Is not an essential protein, but affects the sporulation frequency [H]

COG id: COG0819

COG function: function code K; Putative transcription activator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiaminase-2 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016084
- InterPro:   IPR004305 [H]

Pfam domain/function: PF03070 TENA_THI-4 [H]

EC number: =3.5.99.2 [H]

Molecular weight: Translated: 27371; Mature: 27371

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQDAYYLKAFSEIYHLLAD
CCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
KTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEINDQEMEQHPIAPTCYHYISHIYRQF
CCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHH
AEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWIETYITDELEQQIREEGALVN
CCCCHHHHHHHHCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTWKSDLQSLEKGEE
HHHHCCCCHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQDAYYLKAFSEIYHLLAD
CCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
KTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEINDQEMEQHPIAPTCYHYISHIYRQF
CCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHH
AEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWIETYITDELEQQIREEGALVN
CCCCHHHHHHHHCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTWKSDLQSLEKGEE
HHHHCCCCHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1898926; 9384377 [H]